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Failures of Host Defense Mechanisms
Inherited Immunodeficiencies
Acquired Immunodeficiencies
Initial infection: CCR5 co-rec. on DC, Macrophages, T cells
Late infection: CXCR4 co-rec. on activated T cells
Free virus: blood, sexual fluids, milk
![Macrophage programming and host responses to bacterial ...920447/FULLTEXT01.pdfmanipulate host defense mechanisms to benefit their own survival, replica-tion, or transmission [5].](https://static.cupdf.com/doc/110x72/60e146e593f91f764362ff8b/macrophage-programming-and-host-responses-to-bacterial-920447fulltext01pdf.jpg)
