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    Biology & BehaviorThe Brain, The Nervous System & the Glands

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    The Neurons and the Neurotransmitters

    Neurons

    the specialized cells that conduct impulses through the nervoussystem and contain three major parts "a cell body, dendrites, andan axon

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    anatomy of a neuroncell body #soma$contains the nucleus and carries out the metabolic, or life"sustaining,functions of a neuron.

    dendrites #comes from the Greek word for "tree"$and are the primary receivers of signalsfrom the neurons, they look life the leafless branches of a tree

    axon is the slender, tail"like extension of the neuron that transmits signals to thedendrites or cell body of other neurons and to muscles, glands, and other parts of thebody

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    works of neurons

    a%erent #sensory$neurons relay messages from the senseorgans and receptors "eyes, ears, nose, mouth, and skin ""tothe brain or spinal cord;

    e%erent #motor$neurons convey signals from the centralnervous to the glands and the muscles, enabling the body tomove

    interneurons #thousand of times more numerous thanmotor or sensory neurons$carry information betweenneurons in the brain and between neurons in the spinal cord

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    Glial Cells are specialized cells inthe brain and spinal cord thathold the neurons together,

    remove waste products, such asdead neurons, from the brain byengulfing and digesting them, andthey handle other manufacturing,nourishing and cleanup taskssmaller than neurons and make up

    more than one"half the volume ofthe human brain

    The Synapse is the junctionwhere the axon terminal of asending neuron communicates

    with a receiving neuron across thesynaptic cleft.

    The Myelin Sheath is a white,fatty coating, wrapped aroundsome axons that acts as insulation

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    Neurotransmitters

    Neurotransmitter isa chemical substancethat is released intothe synaptic cleftfrom the axonterminal of a sendingneuron, crosses asynapse, and bindsto appropriatereceptors sites on

    the dendrites or cellbody of a receivingneuron, influencingthe cell either to fireor not to fire

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    why synaptic vesicles can continue topour out

    the cell body of the neuron is alwaysworking to manufacture more of theneurotransmitters

    unused neurotransmitters in thesynaptic cleft may be broken down intocomponents and reclaimed by the axonterminal to be recycled and used again

    the process of REUPTAKE "the

    neurotransmitter is taken from thesynaptic cleft back into the axonterminal, intact and ready for immediateuse thus terminating theneurotransmitter's excitatory orinhibitory e%ect on the receiving neuron

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    the variety ofneurotransmitters

    acetylcholine #Ach$, a neurotransmitterthat exerts excitatory e%ects on theskeletal muscle fibers, causing them tocontract so that the body can move and

    has an inhibitory e%

    ect on the musclefibers in the heart, which keeps theheart from beating too rapidly

    Dopamine #DA$, one of fourneurotransmitters called monoamines,produces both excitatory and inhibitor

    e%ects and is involved in severalfunctions, including learning, attention,movement, and reinforcement

    Norepinephrine #NE$has an e%ect oneating habits #it stimulates the intake ofcarbohydrates$and plays a major role inalertness and wakefulness.

    Epinephrine complementsnorepinephrine by a%ecting themetabolism of glucose and causing thenutrient energy stored in muscles to be

    released during strenuous exercise

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    Serotonin plays animportant role in regulatingmood, sleep, impulsivity,

    aggression, and appetite

    Glutamate is the primaryexcitatory neurotransmitterin the brain

    GABA #gamma"aminobutyric acid$is themain inhibitoryneurotransmitter in thebrain

    Endorphins provide relieffrom pain or the stress ofvigorous exercise andproduce feelings of pleasureand well"being

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    The Nervous Systemthe Central Nervous System & the Peripheral Nervous System

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    2 divisions of the human nervous system

    Central Nervous System #CNS$"composed of brain and the spinal cord

    Peripheral Nervous System "connects the central nervous system to allother parts of the body

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    why is an intact spinal cord

    important to normal functioning?the spinal cord is anextension of the brain that

    reaches from the base of thebrain, through the neck, anddown the hollow center ofthe spinal column; it

    transmits messages betweenthe brain and the peripheralnervous system

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    the brainstem

    brainstem is part of the hindbrain that begins at the sitewhere the spinal cord enlarges as it enters the skull, and ithandles functions that are so critical to physical survival thatdamage to it is life"threatening

    medulla is the part of the brainstem that controls heartbeat,breathing, blood pressure, coughing, and swallowing

    reticular formation #reticular activating system RAS$, plays acrucial role in arousal and attention

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    theCerebellum

    important to the body's ability to execute smooth, skilled movements

    regulates muscle tone and posture

    coordinates the series of movements necessary to perform many simple activities without

    conscious e%ort

    help to heighten ability to focus attention on incoming sensory stimuli and to shiftattention

    may increase our e&ciency in acquiring sensory information and discriminating betweensensory stimuli

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    the Midbrain

    lies between the hindbrain &the forebrain

    act as relay stations throughwhich the basic physiologicalfunctions of the hindbrainare linked to the cognitivefunctions of the forebrain

    substantia nigra is located in

    the midbrain and iscomprised of darkly coverednuclei of nerve cells thatcontrol our unconsciousmotor actions.

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    the thalamus & hypothalamus

    thalamus has two egg"shaped parts, serves asrelay station for virtuallyall the information that

    flows into and out of theforebrain, includingsensory information fromall the senses except smell

    hypothalamus regulates

    hunger, thirst, sexualbehavior, and a wide

    variety of emotionalbehaviors, and internalbody temperature

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    the Limbic Systemgroup of structures in the brain,including the amygdala and thehippocampus, that arecollectively involved in emotional

    expression, memory, andmotivation.

    amygdala plays an important rolein emotion, particularly inresponse to unpleasant or

    punishing stimuli

    hippocampus is located in theinterior temporal lobes and playsa central role in the storing ofnew memories, the response tonew and unexpected stimuli, andnavigational ability

    plays a role in the brain'sinternal representationof space in the form ofneural maps

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    the cerebrum

    most essential part of the brain is the cerebrum & its cortex

    cerebrum is the largest structure in human brain. it is composed oftwo cerebral hemisphere, the left & right which control movement &feeling on the opposing side of the body

    corpus callosum connects the two hemisphere and makes possible thetransfer of information and the coordination of activity between them

    cerebral cortex is the thin gray outer covering about 1/8 inch thick. itis primarily responsible for the higher mental processes of language,

    memory & thinking

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    Cerebral cortexgray outer covering about 1/8inch thick and is primarilyresponsible for the highermental processes

    contain sensory input areaswhere vision, hearing, touchypressure, and temperatureregister

    motor areas, which control

    voluntary movement

    association areas housememories and are involved inthought, perception, andlanguage

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    4 lobes of the cerebral hemisphere

    motor cortex "a strip of tissue at the rear of thefrontal lobes that controls voluntary body

    movement

    plasticity "the brain's capacity to adopt tochanges such as brain damage "of the motorcortex is maintained throughout life

    broca's area "involved in directing the pattern of

    muscle movement required to produce speechsounds in the left hemisphere of the brain

    frontal association areas "involves thinking,motivation, planning for the future, impulsecontrol, and emotional responses

    frontal lobes "begin at the front of the brain and extend to the top center of the

    skull. they contain the motor cortex, Broca's area, and the frontal associationareas

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    the Parietal Lobes "lie

    directly behind the frontallobes, in the top middleportion of the brain andare involved in the

    reception and processingof touch stimuli

    somatosensory cortex,,the site where touch,pressure, temperature,and pain register in thecerebral cortex

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    the Occipital Lobes at

    the rear of the brain areinvolved in the receptionand interpretation ofvisual information

    at the very back ofthe occipital lobesis the primaryvisual cortex, the

    site where visionregisters in thecortex

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    the Temporal Lobes, located slightlyabove ears, are involved in thereception and interpretation ofauditory stimuli. the site in thecortex where the hearing registers isknown as the primary auditory cortex

    wernicke's area "is locatedadjacent to the primaryauditory cortex in the lefttemporal lobe. this is thelanguage area involved in

    comprehending the spokenword and in formulatingcoherent written and spokenlanguage

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    wernicke's asphasia is a type asphasia resulting from

    damage to wernicke's area

    wernicke's patient when asked how he wasfeeling, replied " i that there's an awful lot of

    mung, but i think i've a lot of net and tunged in alittle wheat duhvayden" #Buckingham & Kertesz,1974$

    auditory asphasia#word deafness

    $"the person may hearnormally but may not be able to understand spoken

    language

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    the cerebral hemisphere

    Left hemisphere "handles most of the language functions, includingspeaking, writing, reading, speech comprehension, andcomprehension of the written information

    Right Hemisphere "#controlling the left side of the body$moreadept at visual spatial relations

    auditory cortex in the right hemisphere appears to be farbetter able to process music that the left

    augments left hemisphere's language"processing activities'/#figures out what its meant and who says it$#e.g the balancing act$

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    the right hemisphere's role

    in emotionresponds to the emotional message conveyed byanother's tone of voice

    reading and interpreting nonverbal behavior

    involve in the expression of emotion through tone ofvoice and facial expression

    brain mechanisms responsible for negative emotionsare located in the right hemisphere

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    the Peripheral Nervous

    System

    PNS is made up of all the nerves that connect thecentral nervous system to the rest of the body

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    2 subdivisions of the PNS

    somatic nervous system "

    #1$compose of all the sensory nerves which transmits

    information from the sense receptors "the eyes, ears,nose, tongue, and skin ""to the central nervoussystem,

    #2$all the motor nerves, which relay messages from

    the central nervous system make it possible for youto sense your environment and to move, and they areprimarily under conscious control

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    autonomic nervous system "

    operates without any conscious control orawareness

    transmits messages between the CNS and theglands, the cardiac #heart$muscle, and thesmooth muscles #such as those in the largearteries and the gastrointestinal system$

    ANS is further divided into 2 parts "thesympathetic & the parasympatheticnervous system

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    sympathetic

    nervous systemautomaticallymobilizes thebody's resources,preparing you for

    action

    parasympatheticnervous systembrings these

    heightenedbodily functionsback to normal

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    the Endocrine System

    Endocrine system isa series of ductless

    glands located invarious parts of the

    body, thatmanufactured andsecrete the chemicalsubstances knownas hormones, andsecrete them into

    the bloodstream,thus a%ecting cellsin other parts of thebody

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