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Scabies & Miscbrown

Apr 08, 2018

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    Scabies andScabies andMiscellaneousMiscellaneous

    ParasitesParasites

    Tina Brown, MS, DVMTina Brown, MS, DVM

    Louisiana State UniversityLouisiana State University

    VMED 5365VMED 5365

    March 1, 2007March 1, 2007

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    SarcopticSarcoptic MangeMange

    The parasiteThe parasite Sarcoptes scabeiSarcoptes scabeivar.var. caniscanis

    PRURITICPRURITIC, nonseasonal,, nonseasonal,transmissibletransmissible

    Host specific but can infest man,Host specific but can infest man,cats, ferrets, and foxescats, ferrets, and foxes

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    Sarcoptes scabei var. canisSarcoptes scabei var. canis

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    Life CycleLife Cycle

    Entire life cycle on host (17Entire life cycle on host (17--21 days)21 days)

    Can live off host in correct environmentCan live off host in correct environment

    Female mite burrows into superficialFemale mite burrows into superficial

    layers of the epidermis to lay eggslayers of the epidermis to lay eggs Male mites live on skin surfaceMale mites live on skin surface

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    TransmissionTransmission

    Highly contagiousHighly contagious!!

    50% exposed dogs50% exposed dogs

    will be infectedwill be infected30% of cases,30% of cases,

    exposure unknownexposure unknown

    Mites prefer skinMites prefer skinwith little hairwith little hair

    Ears, Elbows,Ears, Elbows,Hocks,Hocks, AbdomenAbdomen

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    ZoonosisZoonosis

    24 hours to 21 days24 hours to 21 daysafter exposureafter exposure

    Papules on arms,Papules on arms,

    neck, beltlineneck, beltline

    Regress spontaneouslyRegress spontaneously.. 12 to 14 days after.. 12 to 14 days after

    contact is terminatedcontact is terminated

    Severe pruritusSevere pruritus

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    Clinical SignsClinical Signs

    Dogs and humans may haveDogs and humans may havehypersensitivity reaction to mitehypersensitivity reaction to mite

    A few mites can cause generalized pruritusA few mites can cause generalized pruritus

    3 most pruritic skin diseases in dogs3 most pruritic skin diseases in dogs1. Scabies1. Scabies

    2. Flea allergy2. Flea allergy

    3. Food allergy3. Food allergy

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    Clinical SignsClinical Signs

    Dogs of all agesDogs of all ages

    Erythematous papulesErythematous papules+/+/-- lymphadenopathylymphadenopathy

    Occult scabiesOccult scabies--no lesions, only pruritusno lesions, only pruritus

    Suspect in ALL cases of spontaneousSuspect in ALL cases of spontaneousprurituspruritus

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    Clinical Presentation:Clinical Presentation: EAR

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    Clinical Presentation:Clinical Presentation: HOCKS

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    Clinical Presentation:Clinical Presentation: ELBOWSELBOWS

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    DiagnosisDiagnosis

    MultipleMultiple broadbroad superficialsuperficial skin scrapingsskin scrapings

    ScrapeScrape pinnaepinnae, elbows, hocks, elbows, hocks

    Not areas

    of excoriati

    onN

    ot areas

    of excoriati

    on

    Only positive in 20% casesOnly positive in 20% cases

    PinnaPinna--Pedal Reflex

    Pedal Reflex

    Sensitivity as high as 90%Sensitivity as high as 90%

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    DiagnosisDiagnosis

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    DiagnosisDiagnosis

    Fecal sampleFecal sample

    HistopathologyHistopathology

    biopsy papulesbiopsy papules

    mites rarely foundmites rarely found

    Serum antibodySerum antibodytesttest

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    DiagnosisDiagnosis

    Response to treatment is diagnosticResponse to treatment is diagnostictest!!test!!

    If you suspect it treat itIf you suspect it treat itRemember occult scabiesRemember occult scabies

    Commonly misdiagnosed as allergyCommonly misdiagnosed as allergyAtopyAtopy

    Flea allergyFlea allergyFood allergyFood allergy

    Contact dermatitisContact dermatitis

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    TreatmentTreatment

    Treat all in contactTreat all in contactanimalsanimals

    Environmental cleanupEnvironmental cleanupCorticosteroids forCorticosteroids for

    prurituspruritus

    Prednisone 1mg/kg sidPrednisone 1mg/kg sidfor 3for 3--7d7d

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    TreatmentTreatment--topicalstopicals

    Lyme sulfurLyme sulfur

    Every 5Every 5--7 days for 4 to 6 treatments7 days for 4 to 6 treatments

    Amitraz (MitabanAmitraz (Mitaban))Fipronil (Frontline)SprayFipronil (Frontline)Spray

    Topical (pourTopical (pour--on) Ivermectinon) Ivermectin

    0.5mg/kg q14d0.5mg/kg q14d

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    Treatment: Systemic drugsTreatment: Systemic drugs

    Ivermectin (IvomecIvermectin (Ivomec 1%)1%) Very effectiveVery effective

    Extra label useExtra label use

    Beware in sensitive breedsBeware in sensitive breedsCheck heartworm microfilaria statusCheck heartworm microfilaria status

    prior to treatment!prior to treatment!

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    Treatment: Systemic drugsTreatment: Systemic drugs

    Milbemycin (InterceptorMilbemycin (Interceptor ))Safe in ivermectin sensitive breedsSafe in ivermectin sensitive breeds

    33--4x more expensive than Ivermectin4x more expensive than IvermectinAs effective as IvermectinAs effective as Ivermectin

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    Treatment: Systemic drugsTreatment: Systemic drugs

    ****SelamectinSelamectin ( Revolution( Revolution TMTM ))

    Topical avermectinTopical avermectin

    Systemically absorbedSystemically absorbed

    Safe in ivermectin sensitive breedsSafe in ivermectin sensitive breeds

    95.2% effective after 1 dose and95.2% effective after 1 dose and

    100% effective after 2 doses according to100% effective after 2 doses according to

    Pfizer!Pfizer!

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    Treatment: Systemic drugsTreatment: Systemic drugs

    MoxidectinMoxidectin

    Extra label useExtra label use

    Bew

    are in sensitive breedsBew

    are in sensitive breedsAdvantage Multi (Bayer)Advantage Multi (Bayer)

    DoramectinDoramectin

    Extra label useExtra label use

    Beware in sensitive breedsBeware in sensitive breeds

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    ConclusionsConclusions

    Expect to see significant reduction inExpect to see significant reduction inpruritus after twoweeks of treatmentpruritus after twoweeks of treatment

    FAQFAQHow long do you isolate from other pets?How long do you isolate from other pets?

    ??Pfizer suggest 30 days??Pfizer suggest 30 days

    Can cats get scabies?Can cats get scabies?

    Yes, treat all in contact petsYes, treat all in contact pets

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    ScabiesScabies--take home pointstake home points

    VERYVERY pruriticpruritic/papular/papular

    DdxDdx--flea allergy and food allergyflea allergy and food allergy

    Ear pinna, elb

    ows, h

    ocks

    Ear pinna, elb

    ows, h

    ocks

    Best diagnosis=Best diagnosis= response to therapyresponse to therapy

    Treatment optionsTreatment options--considerconsider breedbreed

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    Miscellaneous ParasitesMiscellaneous Parasites

    NotoedresNotoedres

    CheyletiellosisCheyletiellosis

    Otodectic mangeOtodectic mangeChiggersChiggers

    Cat fur miteCat fur mite

    PediculosisPediculosis

    CuterebriasisCuterebriasis

    MyiasisMyiasis

    Fly strikeFly strike

    TicksTicks

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    Notoedric Mange (feline scabies)Notoedric Mange (feline scabies)

    Highly contagiousHighly contagious parasitic diseaseparasitic disease

    Poor offPoor off--host survivalhost survival

    FamilyFamily SarcoptidaeSarcoptidaeCan affect dogs, foxes, rabbits, &Can affect dogs, foxes, rabbits, &

    humanshumans

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    Clinical SignsClinical Signs

    Head MangeHead Mange

    Intense pruritusIntense pruritus

    Papules, scales, crusts, alopecia,Papules, scales, crusts, alopecia,excoriationsexcoriations

    Pinnae, head, neckPinnae, head, neck

    May spread to feet and perineumMay spread to feet and perineum

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    DiagnosisDiagnosis

    SuperficialSuperficial skin scrapingsskin scrapings are usuallyare usuallypositivepositive

    Distributi

    onof lesi

    ons and intensity

    Distributi

    onof lesi

    ons and intensity

    of pruritus are highly suggestiveof pruritus are highly suggestive

    Pinnae, head, neckPinnae, head, neck

    Fecal examination may reveal mitesFecal examination may reveal mites

    HistopathologyHistopathology

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    Notoedres catiNotoedres cati

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    TreatmentTreatment

    Lime sulfur dipsLime sulfur dips

    Use E collar for catsUse E collar for cats

    Amitraz (MitabanAmitraz (Mitaban) dips) dips Ivermectin (IvomecIvermectin (Ivomec 1%)1%)

    Treat all in contact animalsTreat all in contact animals

    Corticosteroids for pruritusCorticosteroids for pruritus

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    CheyletiellosisCheyletiellosis -- WalkingWalking

    DandruffD

    andruffLive on the skin surfaceLive on the skin surface

    Produce a mild dermatitisProduce a mild dermatitis

    Mites can surviveo

    ff the ho

    st fo

    r 10Mites can surviveo

    ff the ho

    st fo

    r 10to 14 daysto 14 days

    Highly contagiousHighly contagious

    Affects cats, dogs, rabbits andAffects cats, dogs, rabbits and

    exposed humansexposed humans

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    Clinical SignsClinical Signs

    Dorsally orientedDorsally orienteddry scaling withdry scaling with

    little or no prurituslittle or no pruritus

    Increasing scaleIncreasing scale

    and pruritus asand pruritus asdisease progressesdisease progresses

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    DiagnosisDiagnosis--CheyletiellaCheyletiella

    Identification of the mite or its eggIdentification of the mite or its egg

    Direct examination with a magnifyingDirect examination with a magnifyingglassglass

    Multiple superficial skin scrapesMultiple superficial skin scrapes

    Scotch tape impressions of dorsumScotch tape impressions of dorsum

    Flea combFlea comb

    Response to treatmentResponse to treatment

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    TreatmentTreatment

    Treat all in contact animals andTreat all in contact animals andenvironmentenvironment

    Easy t

    otreat

    Easy t

    otreatLimeLime sulfursulfur

    Selamectin (Revolution)Selamectin (Revolution)

    Fipronil sprayFipronil spray

    IvermectinIvermectin

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    Otodectic MangeOtodectic Mange -- Ear MitesEar Mites

    Otodectes cynotisOtodectes cynotis Lives in external ear canalLives in external ear canal

    Does not survive in theDoes not survive in theenvironmentenvironment

    ContagiousContagious diseasedisease Affects dogs, cats, andAffects dogs, cats, and

    ferrets as 1ferrets as 1 hostshosts

    Rarely in exposed humansRarely in exposed humans

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    Clinical SignsClinical Signs

    Otitis externaOtitis externa

    Ectopic infestationsEctopic infestations occur whenoccur whenmites colonize the skinmites colonize the skin

    often cause n

    odisease

    often cause n

    odisease

    some animals have a pruritic dermatitissome animals have a pruritic dermatitis

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    DiagnosisDiagnosis

    Direct otoscopic examinationDirect otoscopic examination

    Microscopic examination ofwaxMicroscopic examination ofwax

    Skin scrapingsSkin scrapingsScotch tape impressionsScotch tape impressions

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    TreatmentTreatment

    Treat all in contactTreat all in contactanimalsanimals

    Clean ears toClean ears toremove debrisremove debris

    Miticidal earMiticidal earpreparationspreparations

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    TrombiculaTrombicula

    Diagnosis based onDiagnosis based onhistory, macroscopichistory, macroscopic

    evidenceof parasiteevidenceof parasiteand skin scrapesand skin scrapes

    Treatment withTreatment with

    parasiticidal dips orparasiticidal dips ortopical otictopical oticparasiticideparasiticide

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    Cat Fur MiteCat Fur Mite

    Salt and Pepper appearance to dullSalt and Pepper appearance to dulland dirty coatand dirty coat

    Not highly contagiousNot highly contagious

    Scrape, tape prepScrape, tape prep

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    PediculosisPediculosis -- LiceLice

    Spread by direct contact or bySpread by direct contact or bycontaminated brushes or beddingcontaminated brushes or bedding

    Eggs attached to hairs of the hostEggs attached to hairs of the host

    = nits= nits

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    PediculosisPediculosis

    Can be veryCan be verypruriticpruritic

    Diagnosis tapeDiagnosis tapeprepprep

    Treat all inTreat all in

    contact animalscontact animals

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    CuterebriasisCuterebriasis

    CuterebraCuterebra fly eggsfly eggs

    Skin lesions localized to the head,Skin lesions localized to the head,

    neck,or trunkneck,or trunk

    When larvae enlargeWhen larvae enlarge nodule withnodule withfistulafistula

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    Misc parasitesMisc parasites--take home pointstake home points

    NotoedresNotoedres (feline mange)(feline mange)

    Very pruriticVery pruritic

    Scrapes diagnosticScrapes diagnostic

    CheyletiellaCheyletiella (walking dandruff)(walking dandruff)

    Scrape, tape prep, direct examScrape, tape prep, direct exam

    OtodectesOtodectes

    Ectopic infestations head and neckEctopic infestations head and neck

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    Questions ?Questions ?