HMM for multiple sequences Pair HMM HMM for pairwise sequence alignment, which incorporates affine gap scores. “Hidden” States Match (M) Insertion in x (X) insertion…
Ch 5. Profile HMMs for sequence families Biological sequence analysis: Probabilistic models of proteins and nucleic acids Richard Durbin Sean R. Eddy Anders Krogh Graeme…
Generalized Hidden Markov Models for Eukaryotic Gene Prediction Ela Pertea Assistant Research Scientist CBCB A hidden Markov model (HMM) is a statistical model in which the…
HMM for multiple sequences Pair HMM HMM for pairwise sequence alignment, which incorporates affine gap scores. “Hidden” States Match (M) Insertion in x (X) insertion…