Arthritis Care & Research Vol. 64, No. 10, October 2012, pp 1447–1461 DOI 10.1002/acr.21773 © 2012, American College of Rheumatology SPECIAL ARTICLE 2012 American…

1. GOUT Dr. Mohanad 2. Purines Purines are natural substances found in all of the body's cells, and in virtually all foods. The reason for their widespread occurrence…

1. What is Gout? Gout is defined as a peripheral arthritis, resultingfrom the deposition of MSU crystals at one or morejoints. Characterized by Hyperuricemia Known…

and elbows. Shoulders, hips, spine and sacroiliac joints are rarely involved.5 The arthritis remits completely within few days with or without therapy and then recurs with…

Slide 1 Purine degradation & Gout (Musculoskeletal Block) Purine degradation pathway Fate of uric acid in humans Gout and hyperuricemia: Biochemistry Types Treatment…

Slide 1 Uric Acid Metabolism & Gout Slide 2 Nucleic Acids Mononucleotide Base + Sugar + Phosphoric Acid Base: Purine or Pyrimidine Polynucleotide (DNA or RNA) Mononucleotides…

Slide 1 UNIT IV: Nitrogen Metabolism Nucleotide Metabolism Part 2 Slide 2 Ribonucleases and deoxyribonucleases, secreted by the pancreas, hydrolyze RNA and DNA primarily…

Slide 1 N ON - STEROIDAL ANTI - INFLAMMATORY DRUGS Slide 2 OBJECTIVES At the end of the lecture the students should : Define NSAIDs Describe the classification of this group…

Kidney function test Functions of the kidney Regulation e.g. homeostasis ,water, acid/base Excretion e.g.uric acid, urea, creatinine Endocrine e.g. renin, erythropoietin,…

Non-steroidal anti-inflammatory drugs Non-steroidal anti-inflammatory drugs BY PROF. AZZA EL-MEDANY DR. OSAMA YOUSIF OBJECTIVES At the end of the lecture the students should…