The Effect of a Diabetes-Specific Cognitive Behavioral Treatment Program (DIAMOS) for
Patients With Diabetes and Subclinical Depression: Results of a Randomized
Controlled Trial
Featured Article:
Norbert Hermanns, Andreas Schmitt, Annika Gahr, Christian Herder, Bettina Nowotny, Michael Roden, Christian Ohmann, Johannes Kruse,
Thomas Haak, and Bernhard Kulzer
Diabetes Care Volume 38: 551-560
April, 2015
STUDY OBJECTIVE
• Subclinical depression is associated with a poorer long-term prognosis in diabetes
• Because of the lack of specific intervention concepts, DIAMOS was newly developed and evaluated in a randomized trial
Hermanns N. et al. Diabetes Care 2015;38:551-560
STUDY DESIGN AND METHODS
• DIAMOS is composed of cognitive behavioral interventions to reduce diabetes distress
• The active control group received diabetes education
• The primary outcome was depressive symptoms
• Secondary outcomes were: • Diabetes distress• Well-being• Self-care behavior• Diabetes acceptance• Diabetes treatment satisfaction• HbA1c• Subclinical inflammation
Hermanns N. et al. Diabetes Care 2015;38:551-560
RESULTS
• 214 participants were randomized
• 2-month follow-up revealed a stronger reduction of depressive symptoms in the DIAMOS group than in the control group
• The Patient Health Questionnaire-9 and Diabetes Distress Scale scores displayed significant treatment effects
• Risk of incident major depression in the DIAMOS group was significantly reduced
• Inflammatory variables were not substantially affected
Hermanns N. et al. Diabetes Care 2015;38:551-560
Hermanns N. et al. Diabetes Care 2015;38:551-560
CONCLUSIONS
• DIAMOS effectively lowers depressive symptoms and diabetes-related distress in patients with subclinical depression
• DIAMOS helps to prevent the incidence of major depression
Hermanns N. et al. Diabetes Care 2015;38:551-560
Hermanns N. et al. Diabetes Care 2015;38:551-560
Hermanns N. et al. Diabetes Care 2015;38:551-560
Hermanns N. et al. Diabetes Care 2015;38:551-560
Hermanns N. et al. Diabetes Care 2015;38:551-560
Hermanns N. et al. Diabetes Care 2015;38:551-560