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ProgramforTuesdayOctober10,2017.“IndividualizingDrugTherapyforPatients"

8:30AM–Welcome–Dr.TalaveronandDra.ManguesPartI:Techniquesforoptimalmonitoringanddosing.8:45AM–Nonparametric(NP)modelingdrugbehaviorinpopulationsofpatients.9:30AM–OptimalWeightingofLaboratoryAssayResultsforTDM–1/variance,notCV%.9:50AM-Developingtheassayerrorpolynomial.10:10AM-MultipleModelDosageDesignforMaximallyPreciseDosageRegimens.10:30AM–FindingthemostinformativesamplingtimesforTherapeuticDrugMonitoring10:50AM–Break11:20AM-UsingBestdose-MakingIndividualBayesianPKmodelsforpatients.

1-RegularNPBayesiananalysis–formostclinicalsituations.2-HybridBayesiananalysis–forunusualpatientsandthosewithoutapopulationmodelforthem.3-InteractingMultipleModel(IMM)sequentialBayesiananalysis–changingmodelparametersovertime,trackingdrugbehaviorbestinacutelyill,unstableICUpatientswithhighintra-individualvariability.

11:50AM–Managingpatientsondigoxin.12:10PM–ManagingdialysisandECMOpatients.12:40PM–LunchPartII:Whatareweworkingon?2:00PM–Meropenem:PatientsonCVVH-HospitalUniversitarideBellvitge.IDIBELL,

Barcelona.2:20PM-Antimicrobials:Criticallyillpatients-HospitalClínic,Barcelona.2:40PM–Anoverviewofthepresentcapabilitiesofindividualizingdrug

therapyatSemmelweissUniversity,Budapest-Dr.GellertKarvaly.3:00PM–EducatingPharmacystudents–preparingthemforindividualizingdosage

regimens–Dr.PascalMaire,HospicesCivilsdeLyon,Lyon.3:20PM–Biologics(InflammatoryBowelDisease,Psoriasis,Rheumatoidarthritis)-

HospitalUniversitarideBellvitge.IDIBELL,Barcelona.3:40PM–Busulfan-HospitaldeSantaCreuiSantPau,Barcelona.4:00PM–Pharmacokineticsandpharmacodynamicsinbreastcancerpatients-Dra.Irene Aquerreta,UniversityHospitaldeNavarra,Pamplona.4:20PM-EnteringpatientdataforcreatingpopulationmodelsinPmetricsusinganintuitiveMicrosoftExcelworksheet–Dr.GellertKarvaly.4:40PM-Reviewanddiscussion–allparticipants.4:30PM-Adjourn.

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Eventdetails:When:Tuesday,October10,2017-8:30AM-5:00PMWhere:Col·legiOficialdeFarmacèuticsdeBarcelona,CarrerdeGirona,64,08009Barcelona.Itistheredreverseteardropinthecenterofthemap.

Note–wellbeforetheworkshop,itisstronglyrecommendedthatparticipantsget,read,andbefamiliarwiththebook“IndividualizedDrugTherapyforPatients–BasicFoundations,RelevantSoftware,andClinicalApplications”,editedbyRogerJelliffe,MDandMichaelNeely,MD,publishedbyElsevier.Itsummarizesourcurrentworktodate.Moreinformationisavailableat

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http://store.elsevier.com/product.jsp?isbn=9780128033487&pagename=search

Thisisabookbycliniciansforclinicians.Ifyouwishtoprescribetherapeuticdrugstoeachof yourpatientswith skill, optimal precision, and consideration for eachpatient’s individualneeds,andtominimizethepoortreatmentoutcomesfromblunt,overlysimplisticlastcenturyone-size-fits-alldosingforthefictitiousaveragepatient,thenthisbookisforyou.

However, compareprices fromAmazon.Go tobooks, endenter “IindividualizedDrugTherapy”Itshouldcomeup.

Astoaccommodations,IamtoldthattheNHhotelsaregood,andagoodvalue.Alinkisbelow.Idonotknowhowfartheyarefromourvenue.

https://m.nh-hoteles.es/hoteles/barcelona?campid=8435708&ct=287135524&gclid=Cj0KEQjw_JrMBRDPx_PF9fjmgrcBEiQAKKzUfLk2rFjHin5DShZJlcTT3SfzHmE6si_zu1-eYms-ROEaAlU28P8HAQ&dclid=CK2fwY-Mw9UCFa8S0wodOIwJXg

Adescriptionofthesubwaysystemandalistofotherhotelsisalsoattached.

Verybestregards,

RogerJelliffe,MariaAntoniaMangues,andJosepTalaveron.