GANPAT UNIVERSITY
B. Pharm Semester-I Program
Structure for B. Pharm Semester-I Program
Sr. No.
Course Code
Course Title Teaching Scheme Hrs/Week Type of Course
Theory Credit Weighted
Credit Point Practical Credit Weighted
Credit Point
01 1A01ERM Elementary (Remedial) Mathematics
2 2 10 X 2 = 20 - - - Complementary
02 1A02BCA Basics of Computer Applications
2 2 10 X 2 = 20 3 1.5 10 X 1.5 = 15 Complementary
03 1A03PEN Pharmaceutical Engineering-I 3 3 10 X 3 = 30 3 1.5 10 X 1.5 = 15 Core
04 1A04PUO Pharmaceutical Unit Operations I
3 3 10 X 3 = 30 3 1.5 10 X 1.5 = 15 Core
05 1A05PIC Pharmaceutical Chemistry-I (Inorganic Chemistry)
3 3 10 X 3 = 30 3 1.5 10 X 1.5 = 15 Core
06 1A06APH Anatomy Physiology and Health Education-I
3 3 10X 3 = 30 2 1 10 X 1 = 10 Core
07 1B07ECS English Language and Communication
Skill-I
2 2 10 X 2 = 20 2 1 10 X 1= 10 Common
Total 18 18 180 16 08 80
Total Credit 18+08 = 26 and Weighted Credit Point 180 + 80 = 260
GANPAT UNIVERSITY
B. Pharm Semester-I Program
Structure for B. Pharm Semester-I Program
Sr. No.
Course Code
Course Title
Teaching Hours/week
Theory Credit Practical Credit
01 1A01ERM Elementary (Remedial) Mathematics
2 2 - -
02 1A02BCA Basics of Computer Applications
2 2 3 1.5
03 1A03PEN Pharmaceutical Engineering-I 3 3 3 1.5 04 1A04PUO Pharmaceutical Unit
Operations I 3 3 3 1.5
05 1A05PIC Pharmaceutical Chemistry-I (Inorganic Chemistry)
3 3 3 1.5
06 1A06APH Anatomy Physiology and Health Education-I
3 3 2 1
07 1B07ECS English Language and Communication
Skill-I
2 2 2 1
Total 18 18 16 08
GANPAT UNIVERSITY B.PHARM SEMESTER-I
1A01ERM ELEMENTARY (REMEDIAL) MATHEMATICS
Theory: 30 Hrs (2 Hours / Week; 2 Credit)
1. Algebra: 5 Hrs
Equation reducible to quadratic, simultaneous (linear & quadratic), Determinants, properties of solution of simultaneous equations by Cramer’s rule, matrices, definition of special kind of matrices, arithmetic operations on matrices, pharmaceutical applications of determinants & matrices, Evaluation of En1, En2 & En3 mensuration & its pharmaceutical applications.
2. Measures of dispersion: 4 Hrs Range, average deviation, standard deviation, probability & probability distribution.
3. Permutation ,combination, AP GP, Binomial theorem 4 Hrs
4. Trigonometry: 2 Hrs measurement of angle, T-ratios, addition subtraction & transformation formulae, T-ratios of multiple sub- multiple, allied & certain angles. Application of logarithm in pharmaceutical computation.
5. Analytical plans geometry: 3 Hrs Certain co-ordinates, distance between two points, areas of triangle, a locus point, straight line slope & intercept from double-intercept form, normal (perpendicular form), slope point & two point form, general equation from first degree.
6. Calculus: 12 Hrs
Differential: Limits & functions, definitions of differential coefficient differentiations of standard functions, including a function of a function (chain rule). Differentiation of implicit faction, logarithms differentiation, parametric differentiation, successive differentiation.
Integral: Integration as inverse of differentiation, indefinite integrals of standard forms, integration by parts, substitution & partial fractions, formal evaluation of definite integrals.
Differential equation of first order & first degree, V.S. method, homogeneous & linier differential equation, pharmaceutical application on differential equation.
Reference Books:
1. Remedial Mathematics by Gupta & Prabhakar ; Pragati Prakashan
2. Remedial Mathematics for Pharmacy by R.C.Kachot; Mahajan Prakashan
3. College Mathematics by Kai L. NILSON, Barnes & Noble inc.
GANPAT UNIVERSITY B.PHARM SEMESTER-I
1A02BCA BASICS OF COMPUTER APPLICATIONS
Theory: 30 Hrs (2 Hours / Week; 2 Credit)
1. Computer Fundamentals: 3hrs
Definition, characteristics, history, computer terminology, computer organization, input & output devices, storage devices (including latest devices), classifications of computers (including current computer systems), binary conversions and ASCII code, application of computers in pharmacy, introduction to computer virus.
2. Operating Systems: 3hrs a. Definition, functions of an operating system, types of operating systems
and their characteristics. b. DOS
Introduction, basic DOS commands such as creating directory, copying creating files, backup, restore, autoexec.bat file, config.sys file, etc. internal and external commands for file and directory management.
c. Windows: Desktop, start-menu, control panel, accessories, my computer, my documents, recycle bin, printer and mouse settings, maximizing, minimizing, restoring and closing of windows, windows explorer
3. MS Word: 6hrs Word Essentials, the word workplace, Parts of MS Word screen, Typing and Editing, Finding and Replacing, Autocorrect and Autotext, Reusing Text and Graphics, use of spellcheck & grammer, thesaurus and scientific symbols, viewing of document by various ways Editing Tools, Formatting Text Formatting Text Character, Formatting Paragraphs, Formatting and Sorting Lists, Page Design and Layout, Page Setup : Margins, Page Numbers, and Other Items, Newspaper -style Columns, Working with Tables Creating and formatting of tables and sorting, merging etc. of data in tables. Inserting, deleting and sizing of rows and columns in tables, Opening, Saving and Protecting Documents, Locating and Managing Documents Printing, Assembling Documents with Mail Merge,
4. MS Excel: 6hrs Introduction to EXCEL worksheet, calculations in EXCEL, preparation of templates for application in pharmaceutical chemistry, pharmaceutical technology, pharmacology and pharmacognosy (statistical treatment of data for Beers Lamberts curve, solution of problems based on physical chemistry, pharmaceutical engineering, stability study, area under the curve, bio-assay, bioequivalence study, extraction, Rf value, etc.) Special attention must be given to arithmetic expressions. Hierarchy of operation, library functions such as logarithm, squareroot, standard deviation, sum, average, t-test, ANOVA etc. Drawing graphs in EXCEL line graph, histogram, pie-chart- At least one graph for each discipline of chemistry, pharmaceutical technology, pharmacology and pharmacognosy -Editing chart features such as annotation, labeling of axis, changing legends etc.
5. MS PowerPoint 3hrs Creating and viewing a presentation, adding animations and managing slide shows etc.
6. Introduction to MS Access and Outlook 3hrs
7. Introduction to softwares for viewing pdf documents 3hrs (ADOBE reader, ACROBAT), drawing simple chemical structures (CHEMDRAW, etc.)
8. Networking & Internet: 3hrs Computer networks, networking technology, components of network. Internet – Basic terms, software and hardware requirement for internet, process of internet working, internet tools, Email- components and working, study of pharmaceutical web sites and search engines, searching through pharmaceutical data bases, study of patent websites.
BASICS OF COMPUTER APPLICATIONS PRACTICALS:
30 hours (2 hours / week; 1 credit)
Practical exercises should be based on theoretical topics. Exercise to familiarize students with the use of various DOS commands and WINDOWS environment. Exercises on word processing to execute various commands in preparing and editing documents, preparation of pharmaceutical documents and practical tables of pharmacognosy, pharmaceutical chemistry, pharmaceutics and pharmacology in MS Word. Preparing and editing worksheets in MS EXCEL, drawing graphs, inserting formulas etc. Demonstration of softwares for viewing .pdf documents (ADOBE reader, ACROBAT), drawing simple chemical structures (CHEMDRAW, etc.) Demonstration of pharmaceutical web sites including educational, government, commercial & search engines working with E-mail & e-mail software, patent Web-site.
Reference Books:
1. Windows Vista: Step by Step, Joan Preppernau and Joyce Cox, Prentice Hall of India, New Delhi, 2007.
2. Windows Vista: Plain & Simple, Jerry Joyce, and Marianne Moon, Prentice Hall of India, New Delhi, 2007.
3. DOS commands in easy steps, Harshad Kotecha, Dreamtech Press, New Delhi, 2000.
4. WORD 2000, Guy Hart Davis, BPB Publications, New Delhi, 1999.
5. WORD 2000:fast & easy, Diane Koers, BPB Publications, New Delhi, 2000. 6. Microsoft WORD 2000:Training Guide, Maria Reid, BPB Publications, New Delhi,
2000
7. Exploring Microsoft Office XP, John Breeden and Michael Cheek, BPB Publications, New Delhi, 2001.
8. MS Office by Pierce, Prentice Hall of India, New Delhi, 2007
9. MS Office: Plain & Simple, Jerry Joyce, and Marianne Moon, Prentice Hall of India, New Delhi, 2007.
10. MS Office: Step by Step, Joyce Cox, Prentice Hall of India, New Delhi, 2007.
11 Pharmaceutical Statistics, S.Bolton, Marcel Dekker Inc. – 3rd Edition – 1997.
12 Common Statistical Tests - 1st edition - M.B.Kulkarni, S.B.Ghatpande & S.D.Core, Satyajeet Prakashan, Pune.
13 Taxali R.K., P.C. Software for Windows 98 made simple – 8th Edition – 2002 – Tata Mc, New Delhi.
14 MS – Office by Ed. Bott. & Woddy Leohad, Prentice Hall of India, New Delhi, 1999
15 An Introduction to Medical Statistics – 2nd Edition – Martin Bland – Published by ELBS – Oxford University – Great Britain – 1995
16. Accessing and Analysing Data with MS EXCEL, Cornell, Prentice Hall of India, New Delhi, 2007.
17. Manuals available with the software.
GANPAT UNIVERSITY B.PHARM SEMESTER-I
1A03PEN PHARMACEUTICAL ENGINEERING
Theory: 45 hours (3 Hours / Week; 3 Credit)
1 Introduction: 3hrs
Pharma engineering and its significance, unit operations and unit processes. Unit systems, SI unit, CgS unit, gas constant and conversion of units. Physical quantities,dimensions and units, dimensional equations, dimensional analysis and dimensionless groups. Different types of graphical representation.
2 Stoichiometry: 8hrs General principles, material balance-tie substances, chemical reactions and molal units, rate process, steady, unsteady and equilibrium state, laws of combining weights, applications of gas laws, energy balance, fuels and combustion, etc., Mathematical problems.
3 Fluid Flow: 8hrs Type of steady flow, Reynold number & its significance, types of pressure, viscosity, concept of boundary layers, total energy balance and total mechanical energy balance, losses in mechanical energy of fluids, basic equations of fluid flow, valves, flow meters, manometers. Mathematical problems.
4 Material handling systems: 10hrs Solids handling- storage, conveyers, vacuum & pneumatic conveying. Liquid handling- storage, pumps Gases- Fans, blowers and compressors. Colour coding of Pipelines, use of forklifts and pallets, store design in pharmaceutical industries.
5 Heat Transfer: 10hrs Modes of heat transfer.Conduction- Fourier’s law, resistances in series and parallel, use of mean area and mean temperature difference. Convection-Concept of film, overall coefficient, heat transfer by forced convection in laminar and turbulent flow, condensing vapours, evaluation of individual film coefficients. Radiation-Black body, absorptivity & emmisivity. Heating of fluids, steam as heating medium, purified steam generator, properties and uses of steam, steam traps, study of steam table. Heat exchange equipments-Heat exchangers, condensers, boilers, extended surface scraped and surface equipments etc. applications of heat transfer in industrial processes. Mathematical problems.
6 Mass Transfer: 3hrs Principle, streams in mass-transfer operations, solid/fluid and fluid/fluid mass transfer, influence of mass transfer on unit operations.
7 Materials of Pharmaceutical Plant Construction: 3hrs General study of composition, corrosion resistance, properties, factors affecting the selection of material of pharmaceutical plant construction with special reference to stainless steel and glass. Corrosion-types, causes, theories of corrosion and its prevention.
PHARMACEUTICAL ENGINEERING PRACTICAL: 45 Hours (3 hr/week; 1.5 Credit) Practicals related to topics in pharmaceutical engineering theory should be carried out. Experiments to demonstrate stoichiometry and tie substances in chemical reactions, Study of various flowmeters and ejector pump, Experiment on Reynolds number, Determination of overall heat transfer coefficient, Demonstration of corrosion resistance of various materials. Introduction to engineering drawing – demonstration of orthographic and isometric projections, demonstration of AUTOCAD, interpretation of pharmaceutical building drawings, pharmaceutical machinery drawings. Flowcharting- drawing of simple flowcharts for pharmaceutical processes.
Reference Books:
1 Pharmacopeias like IP, BP, USP, EuP, etc.
2 Elementary Chemical Engineering - Max S. Peters, Published by McGraw Hill Book Company, New York, 1954
3 Perry’s Chemical Engineer’s Handbook - Robert H Perry, Green D.W., Maloney J.O.7th Edition, 1998, McGraw – Hill Inc., New York.
4 Tutorial Pharmacy by Cooper & Gunn, ed. S.J.Carter, CBS Publishers & Distributors, Delhi, 6th Edition, 2000.
5 Unit Operations of Chemical Engineering, 5th edition - McCabe, Smith & Harriott, McGraw – Hill Inc., New York.
6 Pharmaceutical Engineering – K.Sambamurthy, 2002 NAI (P) Ltd., Delhi.
7 Pharmaceutics : The Science of Dosage Form Design - M.E. Aulton.
8 The Theory & Practice of Industrial Pharmacy – Lachman L., Lieberman H.A. & Kanjig J.L., 3rd edition, 1990 Varghese Publishing House, Bombay.
9 Alfonso G. Remington: The Science & Practice of Pharmacy. Vol.I & II. Lippincott, Williams & Wilkins Philadelphia.
10 Pharmaceutics I (Pharmaceutical Engineering), Jani G. K., B. S. Shah Prakashan, Ahmedabad.
11 Pharmaceutical Engineering : Principles and Practice, Subramanyam C.V.S., Thimma J, Suresh S.S. et. al., 2002, Vallabh Prakashan, Delhi.
12 A Textbook of Engineering Drawing Vol. I and II, P.J.Shah,6th Edition, 2003, Ahmedabad
13 Engineering Drawing, 34th edition, N.D.Bhatt Charutar Publishing House, 1994 14 Engineering Drawing & Graphic Technology, 13th edition by Thomas E. French,
Charles J. Vierch, Rebot J. Foster, McGraw Hill International Edition, New Delhi, 1972 15 Introduction to Chemical Engineering by Walter L. Badger & Julius T. Banchero, Mc
graw Hill International edition, New Delhi, 1955.
GANPAT UNIVERSITY B.PHARM SEMESTER-I
1A04PUO PHARMACEUTICAL UNIT OPERATIONS I
THEORY: 45 hrs (3 hours / week; 3 Credit)
1. Filtration 8hrs
Theory and mechanism of filtration process, factors affecting rate of filtration, filter media, filter aids, types of filters, operation of filters, industrial filters-leaf filter, filter press, rotary filter, edge filters, cartridge filters, membrane filters, optimum cleaning cycle in batch filters, etc. Mathematical problems on filtration.
2. Centrifugation: 4hrs Principle and theory of centrifugation, industrial centrifuges-perforated basket centrifuge, sedimentation type centrifuge, continuous centrifuges etc. Applications in pharmacy.
3. Evaporation: 8hrs Basic concept of phase equilibria, factors affecting evaporation, heat transfer in evaporators, Duhring’s Rule and Raoult’s law, evaporators- natural circulation forced circulation & film evaporators, single effect and multiple effect evaporators, mathematic problems.
4. Distillation: 8hrs Physical concepts, vapour liquid equilibrium relationship, volatility & relative volatility, simple steam and flash distillations, batch and continuous distillation, rectification, distillation columns (packed, plate) and their efficiency, McCabe Thiele method for calculation of number of theoretical plates, azeotropic, molecular & steam distillation, mathematical problems.
5 Drying: 9hrs Principle, Moisture content, loss on drying, theory & mechanism of drying, drying rate and time calculations, classification of dryers, factors affecting selection of dryers, dryers used in pharmaceutical industries - tray, vacuum, fluidized bed, spray, freeze, tunnel, Microwave, Infra Red(IR), rotary dryers. Mathematical problems on drying.
6 HVAC(Humidity Ventilation and Air Conditioning): 8hrs Definitions of various terms, wet bulb and adiabatic saturation temperatures, psychrometric chart and determination of humidity, equipments for humidification and de-humidification operations, applications of humidity control in various pharmaceutical processes. Basic concepts and types of refrigeration cycles, air conditioning, applications in pharmacy. Design of HVAC systems.
PHARMACEUTICAL UNIT OPERATIONS-I PRACTICAL 45 Hours (3 Hours / Week; 1.5 Credit) Practicals related to topics in theory should be carried out. Experiments on filtration, factors affecting rate of filtration, demonstration of centrifuge, experiments on evaporation, rectification, determination of HETP, comparison of efficiency of packed and plate columns, steam distillation, experiments to determine EMC of various pharmaceutical raw materials, preparation of drying curves and calculation of rates, demonstration of tray dryer, vacuum dryer, fluid bed dryer, Experiments on determination of humidity and related parameters using DBT/WBT and Dew point methods, demonstration of sling psychrometer, dial type and digital humidity measuring instruments.
Reference Books: 1 Elementary Chemical Engineering - Max S. Peters, Published by
McGraw Hill Book Company, New York, 1954
2 Perry’s Chemical Engineer’s Handbook - Robert H Perry, Green D.W., Maloney J.O.7th Edition, 1998, McGraw – Hill Inc., New York.
3 Tutorial Pharmacy by Cooper & Gunn, ed. S.J.Carter, CBS Publishers & Distributors, Delhi, 6th Edition, 2000.
4. Unit Operations of Chemical Engineering, 5th edition – McCabe, Smith & Harriott, McGraw – Hill Inc., New York.
5 Pharmaceutical Engineering – K.Sambamurthy, 2002 NAI (P) Ltd., Delhi.
6 Pharmaceutics : The Science of Dosage Form Design - M.E. Aulton.
7 The Theory & Practice of Industrial Pharmacy – Lachman L., Lieberman H.A. & Kanjig J.L., 3rd edition, 1990 Varghese Publishing House, Bombay.
8 Alfonso G. Remington: The Science & Practice of Pharmacy. Vol.I & II. Lippincott, Williams & Wilkins Philadelphia.
9 Jani G. K., Pharmaceutics II (Unit Operations), B. S. Shah Prakashan, Ahmedabad.
10 Subramanyam C.V.S., Thimma J, Suresh S.S. et. al., Pharmaceutical Engineering : Principles and Practice, 2002, Vallabh Prakashan, Delhi.
11 Introduction to Chemical Engineering by Walter L. Badger & Julius T. Banchero, Mcgraw Hill International edition, New Delhi, 1955.
12 Filtration in Pharma. Industry by Theodore H. Meltzer, Marcel Dekker Inc.,
New York, 1987. 13 Pharmaceutical Process Engineereing. Anthony J.Hichey & David
Ganderton, Vol-112, Marcel Dekker Inc., New York.2001 14 Fundamentals of HVAC System. Robert McDowell. 5th Ed., Elsevier Inc.
2006.
GANPAT UNIVERSITY B.PHARM SEMESTER-I
1A05PIC PHARMACEUTICAL CHEMISTRY-I (INORGANIC CHEMISTRY)
Theory: 45 Hrs (3 Hours / Week; 3 Credit.)
1. Introduction to Pharmaceutical Chemistry and Pharmacopoeia 2
2. Impurities in Pharmaceuticals: Sources of impurities, tests for purity and identity, limit tests for iron, arsenic, lead, heavy metals, chloride, sulphate. 4
3. An outline of method of preparation, uses, special tests if any, of the following class of inorganic pharmaceuticals included in the current pharmacopoeia:
a) Acids, Bases, Buffers and Waters 5 b) Gastrointestinal agents: Acidifying agents, Antacids, Protective 5 and Adsorbents, Cathartics. c) Major intra and extra-cellular electrolytes: physiological ions, 4
Electrolytes used for replacement therapy, acids-base balance and combination therapy.
d) Essential and trace elements: Transition elements and their 3 compounds of pharmaceutical importance: Iron and haematinics, mineral supplements.
e) Topical agents: Protective, Astringents and Anti-infectives. 4 f) Gases and Vapors: Oxygen, Anesthetics and Respiratory 2
Stimulants. g) Dental products: Dentifrices, Anti-caries agents. 2 h) Complexing and Chelating agents used in therapy. 2 i) Miscellaneous Medicinal agents: Sclerosing agents, Expectorants, Emetics, Poisons and Anti-dotes, Sedatives and Hypnotics etc. 4 j) Pharmaceutical Aids used in pharmaceutical industry: 4
Anti-oxidants, Preservatives, Filter aids, Adsorbents, Diluents, k) Inorganic Radio pharmaceuticals: 4
Nuclear radiopharmaceuticals, reactions, Nomenclature, Methods of obtaining their standards and units of activity, measurements of activity, clinical applications and dosage, hazards and precautions.
PHARMACEUTICAL CHEMISTRY-I PRACTICAL (INORGANIC CHEMISTRY)
45 Hours ( 3 Hours /Week; 1.5 Credit)
1) The backgrounds and systematic qualitative analysis of 18
Inorganic mixture of up to 4 radicals. Six mixtures to be analyzed, Preferably by semi-micro methods.
2) All identification tests for pharmacopoeial inorganic pharmace 6 uticals and qualitative tests for cations and anions should be covered.
3) Limit tests for Cl, SO4, As, Heavy metals and Lead along with a 9 Few modifications.
4) Volumetric Analysis of few important compounds covered in 12 theory.
Reference Books: 1. Inorganic Medicinal and Pharmaceutical Chemistry : J. H. Block,
E. B. Roche, T. O. Soine, C. O. Wilson, Varghese Publishing House, First Indian Reprint, 1986.
2. Bentley and Driver’s Textbook of Pharmaceutical Chemistry: Revised by L. M. Atherden, Oxford University Press, 8th Ed. 1969.
3. The Indian Pharmacopoeia, Latest Edition, Controller of Publications, Delhi.
4. Practical Pharmaceutical Chemistry edited by A. H. Beckett, J. B. Stenlake, CBS Publishers, and First Indian edition 1987.
5. Vogel’s Qualitative Inorganic Analysis Revised by G. Svehla, Longman Gr. Ltd., 7th Ed. 1996.
6. Pharmacopoeia: IP, BP, USP, EP
7. Pharm. Inorganic Chemistry by Kasture
8. Pharm. Inorganic Chemistry by J.S.Quadri
9. Pharm. Inorganic Chemistry by N.C.Chaudhari
GANPAT UNIVERSITY B.PHARM SEMESTER-I
1A06APH ANATOMY PHYSIOLOGY AND HEALTH EDUCATION-I
Theory: 45 hours (3 Hours / Week; 3 Credit) 1. Introduction and Scope of Anatomy and Physiology.
Structural and functional organization of various organ systems. Definitions of various terms used in Anatomy. 2
2. Structure and function of cell and its components wit Special emphasis on molecular
structure of cell membrane, transporter mechanisms, mitochondria and nucleus. Cell cycle and its significance. 4
3. Elementary tissues of the body. Various elementary tissues and their subtypes: epithelial tissue, muscular tissue, connective tissue and nervous tissue. 2
4. Osseous system: Structure and function of skeleton. Histology 4 of bone Classification of joints and their function. Joint disorders.
5. Muscular system: Gross anatomy of skeletal muscles. Names, 4 position, attachments and functions of various muscles. Neuromuscular junction. Physiology of muscle contraction and its components. Properties of skeletal muscles and their significance in health disorders.
6. Haemopoietic system: Composition and functions of blood 6 and its components. Blood groups. Mechanism of blood coagulation. Haemopoiesis. Brief information regarding disorders of blood.
7. Lymph and lymphatic system: Composition, Formation, and 2 circulation of lymph. Extra-cellular, Tran-cellular and intra-cellular fluids and their composition. Basic physiology of spleen and serosal cavities. Disorders of lymphatic system. Body defense Mechanisms & Immunity: Basic principles of 3 immunity, innate immunity, adaptive immunity, immune interactions, immunotherapy, acquired immunity, Reticulo-endothelial System.
8. Local Hormones, Inflammation & Allergy: Functional 4 importance of histamine, 5-hydroxytryptamine (5-HT), Ecosanoids, Platelet-activating factors (PAF) & peptides with specific reference to their role in inflammation & allergy.
9. Digestive system; Gross Anatomy of the Gastrointestinal tract. Structure and functions of various organs of alimentary 5 canal and associated organs like Liver, pancreas and gall bladder. Physiology of digestion and absorption. Brief overview of disorders.
10. Urinary System: Various parts of urinary system and their functions, 4
Structure and functions of Nephron, Physiology of Urine formation, Brief outline of renal diseases, Acid-base balance.
11. Endocrine System: Role of Endocrine Glands in Regulation and 5 Integration of various functions of the Body, Anatomy and Physiology of pituitary gland, thyroid, parathyroid, adrenals, Pancreas, testes and ovary, their hormones and functions with brief outlines of their disorders.
ANATOMY PHYSIOLOGY AND HEALTH EDUCATION-I PRACTICAL
30 Hours (2 Hours / Week; 1 Credit)
1. Study of the human skeleton. 2
2. Study with the help of charts and models of the Digestive and Muscular System and organs 2
3. Histology of elementary tissues and organs of alimentary canal and associated organs 2
4. Hematology experiments 6
Use & Care of Microscope Study of Haemocytometry Hemoglobin estimation Total WBC count Total RBC count Differential WBC count Determination of clotting time and bleeding time of blood, Erythrocyte sedimentation rate (ESR) and Blood Groups Effect of Osmosis on RBC
5. Amphibian Experiments for Study of Properties of Skeletal 3 Muscle using either demonstrations or computer simulated experiments.
Reference Books: (Latest Editions)
1 William J. Larsen: Anatomy – Development, function, Clinical Correlations– Saunders (Elsevier Science)
2 Guyton A.C. and Hall J.E. : Textbook of Medical Physiology – 10th Edition– W.B.Saunders
3 Seeley R.R., StephensT.D. and Tate P.:Anatomy and Physiology 2000– McGraw Hill Co.
4 Waugh A. and Grant A.: Ross and Wilson’s Anatomy and Physiology in Health & illness –– Churchill Livingstone
5 Sobotta : Atlas of Human Anatomy (2 Volumes) –Edited by Putz and R. Pabst, Lippincott, Williams and Wilkins
6 Anne M.R.Agur & Ming J. Lee: Grant’s Atlas of Anatomy –Lippincott, Williams and Wilkins
7 Gosling T.A., Harris P.F., Whitmore I., William, Human Anatomy: Color Atlas and Text –– Mosby
8 Bullock B.L. & Henze R.L., Focus on Pathophysiology –Lippincott
9 Martini, F. Fundamentals of Anatomy and Physiology (Prentice Hall)
10 West, J.B. Best and Taylor’s physiological Basis of Medical Practice (Williams and Wilkins, Baltimore)
11 Tortora G.J. and Anagnodokos, N.P. Principles of Anatomy and Physiology (Harper and Colling Publishers, New York)
12 Derasari and Gandhi’s Elements of Human Anatomy, Physiology & Health Education Eds R. K. Goyal et. al. (B.S.Shah Prakashan, Ahmedabad)
13 Joshi, Vijaya D. Preparatory Manual for Undergraduates Physiology (B.I. Churchill Livingstone) –
14 Chatterjee, C.C.Human Physiology (Medical Allied Agency, Calcutta) –
15 Goyal, R.K. et al.: Practical Anatomy Physiology and Biochemistry (B.S. Shah Prakashan, Ahmedabad)
16 Garg K. et al. A Text Book of Histology (CBS Publishers, New Delhi)
17 Lesson, C.R. et al.: Text Book of Histology (W.B.Saunders Company)
GANPAT UNIVERSITY B.PHARM SEMESTER-I
1B07ECS ENGLISH AND COMMUNICATION SKILL [LEVEL – I (INTERMEDIATE ESL)]
LANGUAGE & COMMUNICATION SKILLS
30 Hours (2 Hours/Week; 2 Credit) Curriculum for Theory Class (Lecture)
The following Course Curriculum of Theory Class is designed to enable the student acquire proficiency that is at par with satisfactory accomplishment of Level – 1 (Intermediate ESL). The teacher should not rely only on teaching of course content only but, he/she also should give assignments periodically to assess progress of the students. Objective of the Course 1. To impart basic skills of communication in English through intensive practice to the first
semester UG students of Pharmacy so as to enable them to function confidently and effectively in that language in the professional sphere of their life.
2. To improve the students’ fluency in English, through a well-developed vocabulary and
enable them to listen to English spoken at normal conversational speed by educated English speakers and respond appropriately in different socio-cultural and professional contexts.
Course Contents: Unit-I Lectures:-7 Language Components: Practical Grammar, Fundamentals of Grammar and Usages, How to Improve the Command over Spoken and Written English with stress on Noun and Verb, Tenses, Adjective, Sentence Errors, Punctuation Marks. Unit-II Lectures:-7 Vocabulary Building: synonyms and antonyms, word roots, one-word substitutes, prefixes and suffixes, study of word origin, analogy, idioms and phrases to encourage the individual to communicate effectively and diplomatically, Common Errors in English. Unit-III Lectures: - 7 Introduction to Communication Skills: Basic Forms of Communication, Process of Communication, Principles of Effective Business Communication, 7 Cs. of Effective Business Communication, Media of Communication, Barriers of Communication (Practical exercise in communication) Unit-IV Lectures:-7 Reading comprehension: reading for facts, guessing meanings from context, scanning, skimming, inferring meaning, critical reading. Reading at various speeds (slow, fast, very fast); reading different kinds of texts for different purposes; reading between the lines Unit-V Lectures:-7 Oral Communication: Principles of Effective Oral Communication, Media of Oral Communication. Group Discussion: dynamics of group discussion, intervention, summarizing, modulation of voice, body language, relevance, fluency and coherence.
Text & Reference Books: 1. Wren & Martin; English grammar and composition, 2003. 2. Hand Book of Practical Comunication Skills-Chrissie Wrought,published by Jaico
Publishing House. 3. Ray, Reuben; Communication today – Understanding Creative Skills, Himalaya
Publishing House, 2001. 4. Effective Technical Communication, M. Ashraf Rizvi, Tata Mc. Graw-Hill Publishing
Company Ltd. 5. A course in English communication by Madhavi Apte, Prentice-Hall of India, 2007. 6. Communication Skills by Leena Sen, Prentice-Hall of India, 2005. 7. Kaul, Asha; Business Communication, 1998, Prentice-Hall of India Ltd, New Delhi 8. Raman, Meenakshi & Sharma Sangeeta, Technical Communication, 2006, OUP, New
Delhi
Curriculum for Laboratory (Practical) Level: I (Intermediate ESL)
30 Hours (2 Hours/Week; 1 Credit) Proficiency Development in Skills of Listening & Speaking
COURSE DESCRIPTION: • Development of listening comprehension and oral proficiency of standard spoken English
at intermediate level. • Listening focuses on note-taking and aural comprehension of standard spoken English
using information from media, discussion and academic contexts. • Speaking focuses on English fluency, proficiency and strategies for discussion and
personal interaction. STUDENT LEARNING OUTCOMES (SLO’S): By the completion of this course, students will be able to: A. Comprehend, recall, and record new information delivered orally in various scaffolded contexts. B. Demonstrate clear pronunciation and adequate speed of speech appropriate to the
intermediate level of English fluency. C. Demonstrate awareness of vocabulary unique to academic, personal and professional
realms by choosing language appropriate to the context. D. Employ strategies such as clarification, explanation and restatement of information to
facilitate discussion in a group. SPECIFIC INSTRUCTIONAL OBJECTIVES: A. Comprehend, recall, and record new information delivered orally in various scaffold
contexts.
o Employ strategies such as predicting, using context, analyzing, discussing, and problem solving to increase comprehension.
o Use note-taking, dictation, summary and methods of information recall. o Use language and content from aural activities in extended discussions, projects, and
practical applications. o Recognize vocabulary and grammatical structures and be able to respond to and use them
appropriately. o Analyze context and cultural references to aid comprehension.
B. Demonstrate clear pronunciation and adequate speed of speech appropriate to the intermediate level of English fluency.
o Demonstrate awareness of mouth, lip, and tongue positions in various segmental and suprasegmental (Morpheme & Phoneme) utterances with significant progress toward improvement of speech clarity
o Demonstrate awareness of stress, word endings, linking, and reductions with significant progress toward improvement of speech clarity.
o Be understood by most listeners with limited need for clarification. C. Demonstrate awareness of vocabulary unique to academic, personal, and professional
realms by choosing language appropriate to context.
o Analyze context and cultural references to aid comprehension. o Recognize vocabulary and grammatical structures and be able to respond to and use them
appropriately.
D. Employ strategies such as clarification, explanation, and restatement of information to facilitate discussion in a group.
o Lead and participate in group discussions. o Use clarifiers, explanation, and restatement accurately so that message is understood by
listeners. o Understand participant roles and work with others as part of a functioning discussion
group. COURSE CONTENT: The content of this course can include the following: o Aural comprehension of standard English speech such as in recorded conversations, mini-
lectures, and instructions o Strategies for taking academic notes in real time o Aural and contextual comprehension of authentic English speech such as in television,
song, radio, or film o Analysis of English speaking country. culture, body language, and behavior as it relates to
English communication o Controlled and spontaneous conversation o Register, formality vs. informality, and polite conventions o Strategies for clarifying, sustaining, facilitating, and leading discussion o Debates, mock trials, role-plays, or group presentations o Out-of-class interview strategies and practice
REPRESENTATIVE METHODS OF INSTRUCTION: Language and utterance analysis is primary to this course, as it provides students with ample opportunity to critically examine the behaviors and nature of the English language. Contrastive analysis with students’ own first language is useful and beneficial. Instruction methods may include: o Presentations of language in audio for deductive or inductive analysis o Pre-teaching of vocabulary to enhance listening activities and post-testing to ensure
retention o Use of cloze exercises, dictations, dicto-comp exercises, and oral and written story
reconstruction o Controlled and spontaneous discussion practice and fluency exercises o Regular interviews, discussions, and oral presentations demonstrating structures practiced
in class o Ample extension of controlled conversation into spontaneous conversation, role-playing,
and improvisation
o Use of listening journals to practice comprehension of English TV, film, radio, and authentic language
o Use of internet activities to deepen and broaden language exposure and acquisition ASSIGNMENTS: Assignments can include: • Exercises from recommended textbooks • Exercises from the media stored at the media center • Mini-lectures, dictations, or dicto-comps in simple language • Out-of-class interviews • Analysis of songs or recorded speeches for presentation in class • Oral presentations, debates, role-plays, and discussions • Language Games / Activities EVALUATION OF STUDENT PERFORMANCE: Typical methods of evaluation may include the following: • Cloze activities to assess critical listening comprehension and accuracy • Listening activities using authentic speech from media to measure applicability of listening
skills • Listening journals to monitor practice and effort in broadening listening skills • Voice recordings to measure accuracy of pronunciation, appropriateness of vocabulary
choice, and progress in speech development • Dictations to measure accuracy of listening comprehension • Role-plays and conversation measure proficiency in speaking and facilitating conversation • Oral projects to measure synthesis of skills in speaking and vocabulary acquisition • Group projects to assess synthesis of skills in listening and facilitating discussion • Objective assessment (objective tests) of discrete skills to measure accuracy and
proficiency • Subjective assessment (oral or written projects) of soft skills such as cultural habits and
language patterns to measure familiarity with U.S. culture • Students receive either a letter grade or credit/no credit based upon satisfactory completion
at the level of 70% or better on all assignments and participatory activities.
RECOMMENDED or REQUIRED TEXT(S): 1. Christy & Carlisi (2000). Tapestry Listening & Speaking 3, 2 ed. Heinle & Heinle: Boston.
nd083840023X
2. Handreddy & Whalley (2006) Mosaic 1 Listening & Speaking. 4th
ed. McGraw-Hill: New York.
3. Lebauer, R. (1999) Learn to Listen, Listen to Learn. 2nd
Ed. Pearson Education ESL: Boston. 0139194320
4. Lim & Smalzer (2005) Listening & Notetaking Series 2: Noteworthy. Heinle & Heinle: Boston. 1413003982.
5. Numrich, C. (2004) Consider the Issues, 3 ed. Pearson Education ESL: Boston. rd
0131115936 6. Roemer, A. (2006). College Oral Communication 2. Heinle & Heinle: Boston.
0618230173 7. Sanabria & Ferre (2003). Northstar Listening & Speaking, High-Intermediate, 2
nd ed.
Pearson Education ESL: Boston. 0201755726
Proficiency Development in Skills of Reading & Writing COURSE DESCRIPTIONS: Development of reading and writing skills at the intermediate level of English acquisition. Reading strategies, fluency, vocabulary, comprehension and paragraphwriting STUDENT LEARNING OUTCOMES (SLO’S): By the completion of this course, students will be able to: Employ strategies such as predicting, previewing, skimming and scanning to modified texts written in English. A. Apply reading and language skills to comprehending texts of increasing grammatical
complexity on familiar and unfamiliar topics B. Demonstrate ability to use new vocabulary in writing, reading, and discussion. C. Compose unified paragraphs with rich sentence variety and depth of expression. SPECIFIC INSTRUCTIONAL OBJECTIVES: A. Employ strategies such as predicting, previewing, skimming and scanning to modify
texts written in English. o Use discussion, pictures and schematic knowledge to predict content in readings. o Use jigsaw readings, timed readings, cloze readings, and other exercises to develop reading
fluency. o Demonstrate comprehension of text in exercises, discussions, quizzes, and tests. B. Apply reading and language skills to comprehend texts of increasing grammatical
complexity on familiar and unfamiliar topics o Identify main idea, support, and textual references in text. o Effectively guess vocabulary in context to facilitate reading speed and efficiency o Use prediction, skimming and scanning, and active questioning to increase comprehension
of abstract and unfamiliar texts o Demonstrate comprehension of text in exercises, discussions, quizzes, and tests. C. Demonstrate ability to use new vocabulary in writing, reading and discussion. o Use vocabulary logs, journals, word lists or other methods of dedicating focus to the
learning of vocabulary. o Use response writing to practice language learned through reading. o Expand upon readings with group discussion, debate or projects. D. Compose unified paragraphs with rich sentence variety and depth of expression. o Understand and demonstrate proficiency in writing topic sentences, support, concluding
sentences, and transitions in paragraph writing. o Recognize rhetorical functions of transitional words and phrases and use them with
accuracy. o Write letters, memos, responses, and short compositions using simple rhetorical modes on
concrete, abstract, familiar, and unfamiliar topics. o Demonstrate ability to connect ideas into composition containing a main idea and support. o Attend to common writing conventions such as punctuation, indentation, paragraphing and
margins, titles, sufficient detail, reasoning, and logical order. o Explore and use language particular to various academic, professional, and personal
communication purposes. COURSE CONTENT: The content of this course comprises a little review and focuses intensely on the mastery of intermediate grammar structures including the following: o Strategies for vocabulary acquisition, retention, and use o Guessing vocabulary from context o Topic sentences, supporting details, concluding and transitional sentences o Identification of main idea, support, inference, fact versus opinion, analysis, and tone o Reading of news and commentary items, opinion pieces, novels and stories o Supportive research using the internet and other sources to broaden and deepen reading
comprehension and writing o Elements of the paragraph and its relationship to the sentence and to the essay
o Various simple rhetorical modes that can include narrative, process, expository, description, and analysis
REPRESENTATIVE METHODS OF INSTRUCTION: Vocabulary, comprehension, and paragraph construction are primary to this course. Activities that increase self-confidence in reading are highly recommended. Contrastive analysis of English vocabulary, prose styles, and writing conventions with that of students’ own first language is useful and beneficial. Instruction methods may include: o Accompanying pre-reading discussions or expansion activities with other media (film,
song, art, etc.) o Use of scaffolding, graphic organizers, and templates to aid the understanding of texts and
writing conventions o Writing activities that include academic, professional, and personal expression o Use of language logs to record writing errors and to inform correction of them o Use of vocabulary journals to record and analyze vocabulary and aid in its retention o Searches of internet texts to broaden understanding and increase exposure to the language ASSIGNMENTS: Each grammar structure taught in the course should be demonstrated effectively by the student in speaking and in writing. Assignments can include: o Sentence and paragraph editing o Professional writing such as letters, memos, and requests o Academic writing such as paragraphs and short compositions on a central theme o Modified readings such as those from an ESL text o Authentic readings o Writing journals o Internet research o Library visits and reading leveled library books o Vocabulary analysis and Language logs EVALUATION OF STUDENT PERFORMANCE: Typical methods of evaluation may include the following: • Reading comprehension activities to gauge accuracy of reading comprehension • Vocabulary quizzes to measure attainment of vocabulary • Written responses to text to measure progress in text-based writing • Editing exercises to demonstrate knowledge of grammar and writing conventions • Group projects to demonstrate depth of understanding of texts and ability to discuss text in
an academic setting • Paragraph assignments to gauge ability to compose effective academic paragraphs • Occasional extended compositions to demonstrate ability to connect ideas and explain Students receive either a letter grade or credit/no credit based upon satisfactory completion at the level of 70% or better on all assignments and participatory activities. RECOMMENDED or REQUIRED TEXT(S): One reading and writing text, or two texts that together address reading and writing are necessary for this course. Some suggestions are the following (see combination suggestions as well): 1. English & Monahan English. (2003). NorthStar Reading & Writing High-Intermediate. 2
nd ed.
Pearson Ed./Longman: Boston. 0201755734. 2. Fellag, L. (2000). Tapestry Reading 3. Thomson/Heinle: Boston. 0838400507. 3. Folse, et al. (2003). Blueprints 1: Composition Skills for Academic Writing. Thomson/Heinle:
Boston. 0-618-14409-9. 4. Hogue & Oshima (2007) Introduction to Academic Writing 3
rd ed. Pearson Ed./Longman: Boston.
0131933957 5. Mikulecky & Jeffries (2005). Reading Power 3
rd ed. Pearson Ed/Longman: Boston. 0-13-130548-4.
6. Pike-Baky & Blass (2002). Mosaic 1 Reading 4th
ed. McGraw-Hill: New York. 7. Pike-Baky & Blass (2002) Mosaic 1 Writing 4
th ed. McGraw-Hill: New York.
8. Weidauer, M. (2000). Tapestry Writing 3. Thomson/Heinle: Boston. 0838400426. 9. Wholey & Henein. (2007). Reading Matters 3. 2nd ed. Thomson/Heinle: Boston. 0618475141
GANPAT UNIVERSITY
B. Pharm Semester-II Program
Structure for B. Pharm Semester-II Program Sr. No.
Course Code
Course Title
Teaching Scheme Hrs/Week Type of Course
Theory Credit Weighted Credit Point
Practical Credit Weighted Credit Point
01 2A01AMB Applied Mathematics (Biostatistics)
2 2 10 X 2 = 20 - - -
Complementary
02 2A02PUO Pharmaceutical Unit operations -II
3 3 10 X 3 = 30 3 1.5 10 X 1.5 = 15
Core
03 2A03PHP Physical Pharmacy 3 3 10 X 3 = 30 3 1.5 10 X 1.5 = 15
Core
04 2A04PCP Pharmaceutical Chemistry-II
(Physical Chemistry)
3 3 10 X 3 = 30 3 1.5 10 X 1.5 = 15
Core
05 2A05PCG Pharmacognosy – I
2 2 10 X 2 = 20 3 1.5 10 X 1.5 = 15
Core
06 2A06APH Anatomy Physiology and Health Education-II
3 3 10 X 3 = 30 2 1 10 X 1 = 10 Core
07 2B07ECS English Language and Communication Skill-II
2 2 10 X 2 = 20 2 1 10 X 1= 10
Common
Total 18 18 180 16 08 80
Total Credit 18+08 = 26 and Weighted Credit Point 180 + 80 = 260
GANPAT UNIVERSITY
B. Pharm Semester-II Program
Structure for B. Pharm Semester-II Program Sr. No.
Course Code
Course Title
Teaching Hours/week
Theory Credit Practical Credit
01 2A01AMB Applied Mathematics (Biostatistics)
2 2 - -
02 2A02PUO Pharmaceutical Unit operations -II
3 3 3 1.5
03 2A03PHP Physical Pharmacy 3 3 3 1.5 04 2A04PCP Pharmaceutical
Chemistry-II (Physical Chemistry)
3 3 3 1.5
05 2A05PCG Pharmacognosy – I
2 2 3 1.5
06 2A06APH Anatomy Physiology and
Health Education-II
3 3 2 1
07 2B07ECS English Language and Communication
Skill-II
2 2 2 1
Total 18 18 16 08
GANPAT UNIVERSITY B. PHARM. SEMESTER- II
2A01AMB APPLIED MATHEMATICS (BIOSTATISTICS)
Theory: 30 hours (2 hours/week; 2 Credit)
1. Sample and sampling methods 06 Introduction, sample and population, importance of sampling, sample and its characteristics. Sampling methods - Simple random sampling – lottery method and random number tables; stratified random sampling; systematic sampling; multistage sampling; cluster sampling. Sampling with and without replacement, sampling distribution, standard error. Example of – simple random sample and stratified random sampling.
2. Statistical inference – tests of hypothesis 08 Introduction, testing of hypothesis – hypothesis, statistical hypothesis, null hypothesis, alternative hypothesis, test of a hypothesis, critical region, types of errors in testing of a hypothesis, level of significance, two-tailed and one-tailed tests, degrees of freedom. Tests of significance – large sample tests; small sample tests – t-test for testing the significance of a single mean, t-test for testing the significance of difference between two means, paired t-test. T-test for testing the significance of an observed correlation coefficient, F-test for equality of two variances, Chi-square test for goodness of fit, Chi-square test for testing independence of attributes, Chi-square test for homogeneity. Example for all types of tests.
3. Correlation and Regression 04 Introduction, types of correlation – positive or negative, simple, multiple or partial. Coefficient of correlation, methods of studying correlation – scatter diagram method, karl pearson’s product moment method, spearman’s rank correlation method. Regression, lines of regression, methods of finding regression lines - scatter diagram method, method of least squares. Examples of all methods for correlation and regression.
4. Analysis of variance 04 Introduction, assumptions of analysis of variance, analysis of variance for oneway classification, analysis of variance for two-way classification. Example of one-way and two-way classifications.
5. Non-parametric tests 04 Introduction, advantages of non-parametric tests, the wilcoxon signed-rank test, the wilcoxon rank-sum test, the kruskal-wallis test. Example of all three non-parametric tests.
6. Experimental designs in clinical research 04 Introduction, types of designs – parallel design, cross-over design – two-way cross-over and three-way cross-over, Replicate design. Merits and demerits of all methods. Wash-out period, carry-over effect.
NOTE: PLEASE COVER PHARMACY APPLICATION RELATED EXAMPLES FOR ALL TOPICS.
Books recommended: 1. Business statistics - J K Sharma, PHI publication. 2. Statistical methods - S P Gupta, Sultan Chand & Sons.
GANPAT UNIVERSITY B. PHARM. SEMESTER- II
2A02PUO PHARMACEUTICAL UNIT OPERATIONS-II
Theory: 45 hours (3 hours/week; 3 Credit) 1 Size Reduction 7
Objectives, theory of size reduction, factors influencing size reduction, energy requirements in size reduction, study of various mills including ball mill, hammer mill, fluid energy mill, colloid mill, cutter mill, etc. Introduction to methods of generating nanoparticles
2 Size Separation 4 Principles of size separation, screens- types, pharmacopoeial standards, screening methods, screening equipments including shaking and vibrating screens, gyratory screens, sedimentation tank, elutriation and cyclone type separators etc. Application of size separation in pharmacy, angle of repose, carr’s index, hausner ratio.
3 Mixing 7 Theory of mixing, mixing mechanisms, solid – solid, solid – liquid and liquid – liquid mixing equipments. Importance of content uniformity in solid dosage forms.
4 Crystallization 9 Objectives, crystal lattice, types of crystal, crystal form, size and habit, formation of crystals, supersaturation theory, factors affecting crystallization process, crystal growth. Study of various types of crystallizers including Swenson walker, tanks, circulating magma, vaccum and crystal cooling crystallizer, etc. Spherical crystallization and its application in ph, brief introduction of co-crystals, polymorphism and amorphous forms of drugs.
5 Extraction 5 Principle, theory, types of extraction, solvents used for extraction, leaching and extraction equipments, small scale and large scale extraction methods, special extraction techniques, application in pharmaceutical industry.
6 Compaction and Compression 6 Objectives, theory, process of compression, effect of compressional force on powders/granules. Kawakita equations. Applications in tablet dosage forms (direct compression, etc.) Hecker and Kawakita equations.
7 Automated Process Control Systems 4 Temperature, pressure, vacuum, flow level and their measurements. Elements of automatic process control systems.
8 Industrial Hazards and Safety Precautions 3 Mechanical, Chemical, Electrical, Fire and dust hazards. Introduction to waste water treatment in industry.
PHARMACEUTICAL UNIT OPERATIONS-II PRACTICALS 45 hours (3 hours/week; 1.5 Credit)
Practicals related to topics mentioned in the theory should be carried out.
Books Recommended : 1 Elementary Chemical Engineering - Max S. Peters, Published by McGraw Hill Book
Company, New York, 1954 2 Perry’s Chemical Engineer’s Handbook - Robert H Perry, Green D.W., Maloney J.O.7th
Edition, 1998, McGraw – Hill Inc., New York. 3 Tutorial Pharmacy by Cooper & Gunn, ed. S.J.Carter, CBS Publishers & Distributors,
Delhi, 6th Edition, 2000. 4 Unit Operations of Chemical Engineering, 5th edition - McCabe, Smith & Harriott, McGraw
– Hill Inc., New York. 5 Pharmaceutics: The Science of Dosage Form Design - M.E. Aulton. 6 The Theory & Practice of Industrial Pharmacy – Lachman L., Lieberman H.A. & Kanjig
J.L., 3rd edition, 1990 Varghese Publishing House, Bombay. 7 Alfonso G. Remington: The Science & Practice of Pharmacy. Vol.I & II. Lippincott,
Williams & Wilkins Philadelphia. 8 Pharmaceutical Process Engineereing. Anthony J.Hichey & David Ganderton, Vol-112, Marcel Dekker Inc., New York.2001
GANPAT UNIVERSITY B. PHARM. SEMESTER- II
2A03PHP PHYSICAL PHARMACY
Theory: 45 hours (3 hours/week; 3 Credit)
1. States of Matter: Introduction, binding forces between molecules, states of matter-solids, liquids, gases, liquid crystals, glassy state, phase equilibrium and phase rule, condensed systems
2. Buffers: Buffer equation, buffer capacity, buffers in pharmaceuticals systems, preparation, stability, buffered, isotonic solutions, tonicity calculations, and methods of adjusting isotonicity.
3. Solubility and Distribution Phenomenon: General principles, solvent-solute interactions, solubility of gases in liquids, solubility of liquids in liquids, solubility of solids in liquids, distribution of solutes between immiscible solvents.
4. Surface and Interfacial phenomenon : Liquid interface, adsorption at liquid interfaces, adsorption at solid interface, applications of surface active agents, electrical properties of interfaces.
5. Disperse systems : a. Colloidal dispersions : Definition, types, properties of colloids, protective colloids, applications of colloids in pharmacy. b. Suspensions and Emulsions : Interfacial properties of suspended particles/globules, settling in suspensions, theory of sedimentation, effect of Brownian movement, sedimentation of flocculated particles, sedimentation parameters, wetting of particles, controlled flocculation, flocculation in structured vehicle, rheological considerations, emulsions ; types, theories, physical stability.
6. Micromeritics: Particle size and distribution, methods for determining particle size, particle shape and surface area, methods for determining surface area, derived properties of powders.
7. Rheology : Newtonian system, Non-Newtonian systems, thixotropy in formulation, determination of rheological properties, applications in pharmacy.
5
3
7
6
10
8
6
PHYSICAL PHARMACY PRACTICALS 45 hours (3 hours/week; 1.5 Credit)
Practicals demonstrating any theoretical aspects of above topics may be carried out.
Experiments on application of phase rule, two component systems, estimation of buffer capacity, preparation of various buffer solutions and their use, experiments on tonicity adjustment, Solubility determination of solids. Determination of surface / interfacial tension, HLB value and CMC of surfactants. Estimation of partition coefficient, Determination of viscosity using different viscometers, Demonstration of Brookefield viscometer, Determination particle size and surface area, derived properties of powders like density porosity, compressibility angle of repose etc. Study on polymorphs, their identification & properties. Studies of different types of colloids and their properties, Determination of sedimentation parameters for suspensions and emulsions, work done in emulsification, etc.
Reference Books : 1. Martin’s Physical pharmacy by Patrick J. Sinko, 5th edition, Lippincott Williams &
Wilkins, New York, 2006. 2. Pharmaceutics: The Science of Dosage Form Design, 2nd edition, Aulton, Michael E.,
Chrchill Livingstone, London, 2002. 3. Remington: The Science and Practice of Pharmacy, Vol-I & II, 20th edition, Gennaro,
Alfonso R.,Lippincott Williams & Wilkins, New York, 2002. 4. Physicochemical Principles of Pharmacy, 3rd edition, Florence, A. T. Atwood, D.
Macmillan Press Ltd., London 1998. 5. Pharmaceutical Dosage Forms and Drug Delivery Systems, Ansel, Howard. C., Allen,
Loyd V., Popovich, Nicholas G. Lippincott Williams & Wilkins, New York, 2002. 6. Cooper and Gunn’s Tutorial Pharmacy, ed. Carter, S. J., 6th edition, CBS Publishers &
Distributors, Delhi, 2000. 7. Bentley’s textbook of Pharmaceutics by E. A. Rawlins. 8. Encydspedia of Pharmaceutical Technology, James Swarbrick, 3rd Ed. Informa Healthcare 2007
GANPAT UNIVERSITY B. PHARM. SEMESTER- II
2A04PCP PHARMACEUTICAL CHEMISTRY-II
(PHYSICAL CHEMISTRY)
Theory: 45 hours (3 hours/week; 3 Credit)
1. Behavior of Gases: 06 Gas laws, ideal gas equation, kinetic theory of gases, deviation from ideal behavior and explanations
2. The liquid state: 06 Physical properties such as surface tension, parachor, viscosity, refractive index, optical rotation, dipole moment of chemical constituents.
3. Solutions: 08 Ideal and real solutions, solutions of gases in liquids, colligative properties, partition co-efficient, conductance and its measurement, Debye-Huckel theory.
3. Thermodynamics: 08 Basic principles, First, Second and Third laws, Zeroth Law, absolute temperature scale, thermochemical equations, phase equilibria and phase rule, One and two component systems.
4. Adsorption: 04 Basic principles, Freundlich and Gibbs adsorption isotherms, Langmuir theory of adsorption, Pharmaceutical Applications
5. Photochemistry 05 Basic principles, Consequence of light adsorption, Jablonski diagram, Lambert-Beer Law, Quantum efficiency.
6. Chemical kinetics 08 Zero, first and second orders reactions, complex reaction, theories of reaction kinetics, characteristics of homogeneous and heterogeneous catalysts, acid-base enzyme catalysis.
PHARMACEUTICAL CHEMISTRY-II PRACTICAL
(PHYSICAL CHEMISTRY) 45 hours (3 hours/week; 1.5 Credit)
Experiments on surface tension and viscosity, partition coefficient, adsorption, order of reaction (First and Second), refractive index and molar refraction.
Reference Books: 1. Text book of Physical Chemistry: Semuel Glasstone, Macmillan India Limited, 2nd
Ed. 1995. 2. Elements of physical chemistry; Peter Atkins, Julio de paula, Oxford University
Press, 4th Ed. 2007. 3. Physical Chemistry by Bahl & Tuli
GANPAT UNIVERSITY B. PHARM. SEMESTER- II
2A05PCG PHARMACOGNOSY-I
Theory; 30 hours (2 hours/week, 2 credits,)
1. Definition, history, scope and development of Pharmacognosy. 01
2. Sources of drugs: 02 Plant, biological, marine, and mineral. Tissue culture as source of drugs.
3. Classification of drugs: 02 Alphabetical, Morphological, Taxonomical, Chemical and Pharmacological.
4. Morphology: 05 Seed, root, stem, leaf, bark, wood, flower and fruit. Modification of root and stem. Histology of dicot and monocot root, stem and leaf.
5. Taxonomy: 05 Studies of family with reference to medicinally important plants such as Apocynaceae,
Solanaceae, Rutaceae, Umbeliferae, Leguminosae, Liliaceae, Labiatae, Cruciferae, Rubiaceae
6. Cultivation, collection, processing and storage of crude drugs. 03 Factors influencing cultivation of medicinal plants. Types of soils and fertilizers of common use. Plant hormones and their applications. Polyploidy, mutation and Hybridization with reference to medicinal plants.
7. Quality control of crude drugs: 03 Adulteration of crude drugs and their detection by organoleptic, microscopic, physical, chemical, biological and other method of evaluation.
8. An introduction to active constituents of drugs and their classification and properties. 01
9. Systemic pharmacognostic study of the following: 08
a) Carbohydrates and derived products: Agar, Guar gum, Acacia, Honey, Isabgol, Pectin, Starch, Stercuila, Tragacanth and sodium alginate.
b) Lipids: Beeswax, castor oil, coca butter, cod liver oil, hydnocarpus oil, seasame oil and wool fat, kokum butter, lard, linseed oil, rice bran oil, shark liver oil.
PHARMACOGNOSY-I PRACTICAL
45 hours (3 hours/week; 1.5 Credit)
1. Morphology of plant parts indicated in theory. 2. Microscopy of monocot and dicot root, stem and leaf. 3. Microscopic measurements of cell and cell contents: starch grains, calcium oxalate
crystals and phloem fibers. Measurement of leaf constants such as stomatal number, SI, vein islet number, vein termination number, palisade ratio.
4. Identification of crude drugs belonging to carbohydrates and lipids. 5. Preparation of herbarium sheets.
Reference Books: 1. Botany for degree students: A. C. Dutta, Calcutta Oxford University Press, New
Delhi, 6th Edition, 2002. 2. College botany Vol-I-III, Ganguly H.C., Das K.S., and Dutta C., New Central
Book Agency [P] Lt., 2006. 3. Pharmacognosy: C. K. Kokate, A. P. Purohit, S. B. Gokhale, Nirali Prakashan
Pune, 9th edition, 1998. 4. Pharmacognosy: V. E. Tyler, L. R. Brady, J. E. Habbers, Lea and Febiger
Philadelphia, 9th edition, 1988. 5. A Text book of pharmacognosy: C. S. Shah, J. S. Quadry, B. S. Shah Prakashan,
Ahmedabad, 13th revised edition, 2007-08. 6. Trease and Evan’s Pharmacognosy: W. C. Evans, W. B. Saunders Company,
Singapore 14th edition, 1997. 7. Textbook of Pharmacognosy: T.E. Wallis, CBS Publishers and Distributors, New
Delhi, 5th Edition, reprinted, 2003.
Practical Books: 1. Practical Pharmacognosy by C. K. Kokate, Vallabh Prakashan, Delhi, 4th edition,
1997. 2. Practical Pharmacognosy, Technique and Experiment by C. K. Kokate and S. B.
Gokhale, Nirali Prakashan, Pune, 3rd edition, 1996.
GANPAT UNIVERSITY B. PHARM. SEMESTER- II
2A06APH ANATOMY PHYSIOLOGY AND HEALTH EDUCATION-II
Theory: 45 hours (3 hours/week; 3 Credit )
1. Cardiovascular System: 09 Anatomy of the heart, Circulatory system including Arterial and Venous system with special reference to the names and positions of main arteries and veins, Properties of Cardiac muscle, Electrocardiogram (ECG), Blood pressure and its regulation, Coronary circulation, Basic understanding of Cardiac cycle and Heart sounds, Renin Angiotensin system and its significance, Cardiac output, Brief introduction to cardiovascular disorders.
2. Respiratory System: 04 Anatomy of Respiratory organs, Physiology (mechanism and regulation) of respiration, Physiology of Internal Respiration, Brief overview of measuring lung functions i.e. respiratory volumes, Vital capacity, Respiratory disorders.
3. Nervous System: 13 Neurons and Nerve Fibers, Physiology of Nerve excitation and conduction, Overview of Neurotransmitters, Divisions of Nervous System, Central Nervous System (Brain & Spinal Cord), Function of different parts of brain and spinal cord, Reflex action, Electroencephalogram (EEG), Specialized functions of the brain including Limbic system and Reticular activation and Inhibiting System, Peripheral Nervous System (PNS) (Cranial nerves & spinal nerves): Description of spinal and cranial nerves, Physiology and functions of the Autonomic Nervous System, brief introduction to CNS disorders.
4. Special Senses: 05 Basic anatomy of the Eye and the Ear, Physiology of Vision, Hearing and Equilibrium Balance. Organs of Taste (tongue), Olfaction, Touch, Pressure, etc., Structure and Functions of Skin. Regulation of Body Temperature, Disorders.
5. Reproductive System: 04 Gross Anatomy and Histology of Male and female reproductive Organs and their Functions, Physiology of Menstruation, Coitus and Fertilization, Sex differentiation, Oogenesis and spermatogenesis, implantation of embryo, pregnancy and its maintenance, parturition.
6. Physiology of Ageing 01 7. Health Education 09 a. Concepts of health & disease, disease causing agents and prevention of disease b. Classification of food requirements, balanced diet, nutrirional deficiency disorders their treatment and prevention specifications for drinking water c. Demography and family planning: Demography cycle, family planning various contraceptive methods, medical termination of pregnancy d. Brief outline of communicable disease their causative agents, mode of transmissions and
prevention (Chicken pox, measles, influenza, diphtheria, whooping cough, tuberculosis, poliomyelitis, hepatitis, cholera, typhoid, food poisoning, helmenthiasis, malaria, filarasis, rabies, trachoma, tetanus, leprosy, syphilis, gonorrhea and AIDS)
e. First Aid: Emergency treatment of shock, snack bites, burns, poisoning, fractures, resuscitation methods.
ANATOMY PHYSIOLOGY AND HEALTH EDUCATION-II PRACTICAL 45 hours (2 hours/week; 1 Credit)
1. Biochemical Analysis of Urine 02 Physical Characteristics, Normal Constituents, Abnormal Constituents
3. Study with the help of charts and models of the Anatomy of following ystems: 07 Heart, Arterial System, Venous System, Respiratory System, Urinary System, Male and Female Reproductive System, Eye and Ear, Nervous System
3. Histology of Various organs of above mentioned Systems 02 4. Determination of body temperature, pulse rate, blood pressure, listening to heart
sounds, demonstration of ECG 01 5. Determination of Lung Volumes and Vital Capacity 01 6. Study of Reflexes, Vision and Hearing capacity 02
Reference Books: (Latest Editions) : 1 William J. Larsen: Anatomy – Development, function, Clinical Correlations –
Saunders (Elsevier Science) 2 Guyton A.C. and Hall J.E. : Textbook of Medical Physiology – 10th Edition–
W.B.Saunders 3 Seeley R.R., Stephens T.D. and Tate P.: Anatomy and Physiology 2000 – McGraw
Hill Co. 4 Waugh A. and Grant A.: Ross and Wilson’s Anatomy and Physiology in Health &
illness –– Churchill Livingstone 5 Sobotta : Atlas of Human Anatomy (2 Volumes) –Edited by Putz and R. Pabst,
Lippincott, Williams and Wilkins 6 Anne M.R.Agur & Ming J. Lee: Grant’s Atlas of Anatomy –Lippincott, Williams
and Wilkins 7 Gosling T.A., Harris P.F., Whitmore I., William, Human Anatomy: Color Atlas and
Text –– Mosby 8 Bullock B.L. & Henze R.L., Focus on Pathophysiology –Lippincott 9 Martini, F. Fundamentals of Anatomy and Physiology (Prentice Hall) 10 West, J.B. Best and Taylor’s physiological Basis of Medical Practice (Williams and
Wilkins, Baltimore) 11 Tortora G.J. and Anagnodokos, N.P. Principles of Anatomy and Physiology (Harper
and Colling Publishers, New York) 12 Chatterjee, C.C.Human Physiology (Medical Allied Agency, Calcutta) 13 Lesson, C.R. et al.: Text Book of Histology (W.B.Saunders Company) 14 Health Education by Ashok K.Gupta 15 Health Education & Community Pharmacy by P.C.Dandiya 16 Health Education & Community Pharmacy by V.D.Shivare 17 Health Education by N.S.Parmar 18 Health Education by Dr.Anee & Ahmed Siddiqui
GANPAT UNIVERSITY
B. Pharm. Semester- II 2B07ECS ENGLISH AND COMMUNICATION SKILL-II
Theory: 50 Hours (2 Hours/Week; 2 Credits)
[Level – I (Advanced ESL)]
LANGUAGE & COMMUNICATION SKILLS Curriculum for Theory Class (Lecture)
The following Course Curriculum of Theory Class is designed to enable the student acquire proficiency that is at par with satisfactory accomplishment of Level – 2 (Advanced ESL). The teacher should not rely only on teaching of course content only but, he/she also should give assignments periodically to assess progress of the students. Objectives: • To develop the project writing and presentation skills of the undergraduate
students. • The students should be able to act with confidence, should be clear about their
own personality, character and future goals. Course Contents: Unit-I Lectures:-7 Project, Report and Proposal Writing – How to Write an Effective Report, Basics of Project Report Writing, Selecting material for expository, descriptive , and argumentative pieces, formal report; summarizing and abstracting ; expressing ideas within a restricted word limit; paragraph division; the introduction and the conclusion; listing reference material; use of charts, graphs and tables ; punctuation and spelling; semantics of connectives, modifiers and modals; variety in sentences and paragraphs.
Unit-II Lectures:-7 Presentation: How to Make Presentation, Presentation Tools along with Guidelines of Effective Presentation, Boredom Factors in Presentation and How to Overcome Them, Interactive Presentation & Presentation as a part of Selection Process, Art of Effective Listening.
Unit-III Lectures:-7 Resume Writing and Interview: Guidelines for Writing an Impressive Resume, How to face an Interview Board, Proper Body Posture, Importance of Gestures and Steps to Succeed in Interviews, Practice of Mock Interview in classrooms, Self introduction – highlighting positive and negative traits and Face to Face Communication. Unit-IV Lectures:-7 Official and Miscellaneous Writing: Notice, Agenda & Minutes of Meeting, Advertising, Delivery of Public Speech, Types of Application, Form & Content of an Application, Drafting of Job Application, Preparation of Resume/CV and Bio-data.
Unit-V Lectures:-7 Leadership – Quality of a Leader, Leadership Quiz with Case Study, Knowing Your Skills and Abilities. Introduction to Group Discussion Techniques with Debate and Elocution, Increase your Professionalism. Audio – Video Recording of Dialogue Sessions on Current Topics related to Economy, Education System, Environment, Politics etc. Text & Reference Books: 1. Reuben, Ray; Communication today – understanding creating skills, Himalaya
Publishing House, 2001. 2. Stephen R. Covey; The seven habits of highly effective people. 3. Rogets Thesaurus 4. Barker, Alan, Improve Your Communication Skills, 2007, Kagan Page (I) Pvt.
Ltd. New Delhi 5. Taylor, Poul J & O’Driscoll Michael P., The Handbook of interviewing, 2001,
Infinity Books, New Delhi 6. Raman, Meenakshi & Sharma Sangeeta, Technical Communication, 2006,
OUP, New Delhi 7. Academic Writing- A Practical guide for students by Stephen Bailey, Rontledge
Falmer, London & New York, 2004. 8. Body Language- Your Success Mantra by Dr. Shalini Verma, S. Chand, 2006. 9. Technical Report Writing Today by Daniel G. Riordan & Steven E. Pauley,
Biztantra Publishers, 2005. 10. Basic Communication Skills for Technology by Andra J. Rutherford, 2nd
Edition, Pearson Education, 2007. 11. Communication Skills for Engineers by Sunita Mishra & C. Muralikrishna,
Pearson Education, 2007. 12. English for Professional Students, by S S Prabhakara Rao. 13. The Oxford Guide to Writing and Speaking, John Seely, Oxford. 14. Grammar Games, Renvolucri Mario, Cambridge University Press.
Curriculum for Laboratory (Practical) Practicals: 50 Hours (2 Hours/Week; 1 Credit0
Level: II (Advanced ESL)
Proficiency Development in Skills of Listening & Speaking COURSE DESCRIPTIONS: • Development of listening comprehension and oral proficiency of standard
spoken English at the Advanced level. • Listening focuses on note-taking and aural comprehension of standard spoken
English in academic situations, media, and discussion. • Speaking focuses on fluency of English speech, proficiency in clarifying
and restating, and strategies for facilitating discussion.
STUDENT LEARNING OUTCOMES (SLO’S): By the completion of this course, students will be able to: A. Comprehend, recall, and record new information delivered orally in various
contexts. B. Demonstrate clear pronunciation and adequate speed of speech appropriate to
the high-intermediate level of English fluency. C. Demonstrate awareness of vocabulary unique to academic and professional
realms by choosing language appropriate to context. D. Employ strategies such as clarification, explanation, and restatement of
information to facilitate discussion in a group. E. Demonstrate critical thinking in discussion based on listening activities. SPECIFIC INSTRUCTIONAL OBJECTIVES: A. Comprehend, recall, and record new information delivered orally in
various contexts. o Employ strategies such as predicting, using context, analyzing, discussing, and
problem solving to increase comprehension. o Use note-taking, dictation, summary and methods of information recall. o Use language and content from aural activities in extended discussions,
projects, and practical applications. o Recognize vocabulary and grammatical structures and be able to respond to
and use them appropriately. o Analyze context and cultural references to aid comprehension. B. Demonstrate clear pronunciation and adequate speed of speech
appropriate to the high-intermediate level of English fluency. o Demonstrate awareness of mouth, lip, and tongue positions in various
segmental and suprasegmental (Morpheme & Phoneme) utterances with significant progress toward improvement of speech clarity
o Demonstrate awareness of stress, word endings, linking, and reductions with significant progress toward improvement of speech clarity.
o Be understood by most listeners with limited need for clarification. C. Demonstrate awareness of vocabulary unique to academic and
professional realms by choosing language appropriate to context. o Analyze context and cultural references to aid comprehension. o Recognize vocabulary and grammatical structures and be able to respond to
and use them appropriately. D. Employ strategies such as clarification, explanation, and restatement of
information to facilitate discussion in a group. o Lead and participate in group discussions. o Use clarifiers, explanation, and restatement accurately so that message is
understood by listeners. o Understand participant roles and work with others as part of a functioning
discussion group. E. Demonstrate critical thinking in discussion based on listening activities.
o Expand discussions to beyond surface level showing depth of understanding. o Defend a position adequately and be able to persuade someone to one’s point
of view. o Give reasons and explanations that directly respond to comments from others
COURSE CONTENT: The content of this course can include the following: o Aural comprehension of unmodified standard American speech such as in
recorded conversations, mini-lectures, and instructions o Strategies for taking academic notes in real time o Aural and contextual comprehension of authentic English speech such as in
television, song, radio, or film o Analysis of English culture, body language, and behavior as it relates to
English communication o Controlled and spontaneous conversation o Register, formality vs. informality, and polite conventions o Strategies for clarifying, sustaining, facilitating, and leading discussion o Debates, mock trials, role-plays, or group presentations o Out-of-class interview strategies and practice o Advanced Language Games and Activities REPRESENTATIVE METHODS OF INSTRUCTION: Language and utterance analysis is primary to this course, as it provides students with ample opportunity to critically examine the behaviors and nature of the English language. Contrastive analysis with students’ own first language is useful and beneficial. Instruction methods may include: o presentations of language in film or audio for deductive or inductive analysis o pre-teaching of vocabulary to enhance listening activities and post-testing to
ensure retention o use of cloze exercises, dictations, dicto-comp exercises, read and look up
exercises and oral and written story reconstruction o controlled and spontaneous discussion practice and fluency exercises o regular interviews, discussions, and oral presentations demonstrating structures
practiced in class o ample extension of controlled conversation into spontaneous conversation, role-
playing, and improvisation o use of listening journals to practice comprehension of English TV, film, radio,
and authentic language o use of internet activities to deepen and broaden language exposure and
acquisition ASSIGNMENTS: Assignments can include: • recording one’s voice on tape or digital media for grading and analysis of
speech development • exercises from the CD/tape package of the textbook • exercises from the internet or media stored at the media center • mini-lectures, dictations, or dictocomps in simple language • out-of-class interviews • film and television reviews • listening journals • analysis of songs or recorded speeches for presentation in class • oral presentations, debates, role-plays, and discussions • Language Games and activities
EVALUATION OF STUDENT PERFORMANCE: Typical methods of evaluation may include the following: Cloze activities to assess critical listening comprehension and accuracy • Listening activities using authentic speech from media to measure applicability
of listening skills • Listening journals to monitor practice and effort in broadening listening skills • Voice recordings to measure accuracy of pronunciation, appropriateness of
vocabulary choice, and progress in speech development • Dictations to measure accuracy of listening comprehension • Role-plays and conversation measure proficiency in speaking and facilitating
conversation • Oral projects to measure synthesis of skills in speaking and vocabulary
acquisition • Group projects to assess synthesis of skills in listening and facilitating
discussion • Objective assessment (objective tests) of discrete skills to measure accuracy
and proficiency • Subjective assessment (oral or written projects) of soft skills such as cultural
habits and language patterns to measure familiarity with U.S. culture Students receive either a letter grade or credit/no credit based upon satisfactory completion at the level of 70% or better on all assignments and participatory activities. RECOMMENDED or REQUIRED TEXT(S): 1. Fragiadakis & Maurer (2000). Tapestry Listening & Speaking 4, 2 ed.
Heinle & Heinle: Boston. nd
0838400299 2. Delk, C. (2006). College Oral Communication 3. Heinle & Heinle: Boston.
0618230181 3. Dunkel & Pialorsi (2005) Listening & Notetaking Series 3: Advanced
Listening Comprehension. Heinle & Heinle: Boston. 1413003966. 4. Handreddy & Whalley (2006) Mosaic 2 Listening & Speaking. McGraw-
Hill: New York. 5. Numrich, C. (2001) Raise the Issues, 2 ed. Pearson Education ESL: Boston.
nd0201621002
6. Schmidt & Solorzano (2003). Northstar Listening & Speaking, Advanced, 2
nd ed. Pearson Education ESL: Boston. 0201755742
Proficiency Development in Skills of Reading & Writing COURSE DESCRIPTION: • Development of reading and writing skills at the high-intermediate level of
English acquisition. • Reading strategies, fluency, vocabulary, comprehension, paragraph and essay
writing STUDENT LEARNING OUTCOMES (SLO’S):
By the completion of this course, students will be able to: A. Employ strategies such as predicting, previewing, skimming and scanning to
unmodified texts written in standard American English.
B. Demonstrate critical thinking in text comprehension and subsequent discussion and elaboration.
C. Demonstrate ability to use new vocabulary in writing, reading, and discussion. D. Compose essays with unified theme, strong paragraphs, and effective sentence
construction. SPECIFIC INSTRUCTIONAL OBJECTIVES: A. Employ strategies such as predicting, previewing, skimming and scanning
to unmodified texts written in standard American English.
o Use discussion, pictures, and schematic knowledge to predict content in readings.
o Use jigsaw readings, timed readings, cloze readings, and other exercises to develop reading fluency.
o Demonstrate comprehension of text in exercises, discussions, quizzes, and tests.
B. Demonstrate critical thinking in text comprehension and subsequent
discussion and elaboration o Analyze and explicate text in discussion and writing. o Use inferences, cultural references, and cues to increase comprehension. o Use prediction, skimming and scanning, and active reading strategies to
increase comprehension of abstract and unfamiliar texts. o Demonstrate comprehension of text in exercises, discussions, quizzes, and
tests. o Expand on ideas from text through discussion, response, and essay. C. Demonstrate ability to use new vocabulary in writing, reading, and
discussion. o Use vocabulary logs, journals, word lists, or other methods of dedicating focus
to the learning of vocabulary. o Use response writing to practice language learned through reading. o Expand upon readings with group discussion, debate, or projects. D. Compose essays with unified theme, strong paragraphs, and effective
sentence construction. o Understand and demonstrate proficiency in writing theses, connected support
paragraphs, transitions and rhetorical devices, and other common conventions of essay writing.
o Compose message with awareness of audience. o Write reports, responses, and essays using various rhetorical modes on
concrete, abstract, familiar, and unfamiliar topics while showing attention to common writing conventions.
o Attend to common writing conventions such as punctuation, indentation, paragraphing and margins, titles, sufficient support, detail, reasoning, and logical order.
o Explore and use language particular to various academic and professional communication purposes.
COURSE CONTENT: The content of this course comprises a little review and focuses intensely on the mastery of intermediate grammar structures including the following: o Strategies for vocabulary acquisition, retention, and use o Guessing vocabulary from context
o Topic sentences, supporting details, concluding and transitional sentences o Identification of main idea, support, inference, fact versus opinion, analysis,
and tone o Reading of news and commentary items, opinion pieces, novels and stories o Supportive research using the internet and other sources to broaden and deepen
reading comprehension and writing o Elements of the paragraph and its relationship to the sentence and to the essay o Various simple rhetorical modes that can include narrative, process, expository,
description, and analysis REPRESENTATIVE METHODS OF INSTRUCTION: Vocabulary, comprehension, and paragraph construction are primary to this course. Activities that increase self-confidence in reading are highly recommended. Contrastive analysis of English vocabulary, prose styles, and writing conventions with that of students’ own first language is useful and beneficial. Instruction methods may include:
o accompanying pre-reading discussions or expansion activities with other media
(film, song, art, etc.) o use of scaffolding, graphic organizers, and templates to aid the understanding
of texts and writing conventions o writing activities that include academic and professional expression o use of language logs to record writing errors and to inform correction of them o use of vocabulary journals to record and analyze vocabulary and aid in its
retention o searches of internet texts to broaden understanding and increase exposure to the
language ASSIGNMENTS: Each grammar structure taught in the course should be demonstrated effectively by the student in speaking and in writing. Assignments can include: • paragraph editing and peer review of essays • professional writing such as reports, research, or surveys • academic essays • readings from an ESL text • authentic readings • writing journals • internet research • library visits and reading leveled library books • vocabulary analysis • language logs (Visit the site and complete the tasks) EVALUATION OF STUDENT PERFORMANCE: Typical methods of evaluation may include the following: • Reading comprehension activities to gauge accuracy of reading comprehension • Vocabulary quizzes to measure attainment of vocabulary • Written responses to text to measure progress in text-based writing • Editing exercises to demonstrate knowledge of grammar and writing
conventions • Group projects to demonstrate depth of understanding of texts and ability to
discuss text in an academic setting
• Paragraph assignments to review ability to compose effective academic paragraphs
• Full-length compositions graded on ability to express ideas in standard English • Library activities to measure skill in research Students receive either a letter grade or credit/no credit based upon satisfactory completion at the level of 70% or better on all assignments and participatory activities. RECOMMENDED or REQUIRED TEXT(S):
One reading and writing text, or two texts that together address reading and writing are necessary for this course. Some suggestions are the following (see combination suggestions as well):
1. Blass & Pike-Baky (2002). Mosaic 2 Writing 4th
ed. McGraw-Hill: New York. 0-07-246911-0.
2. Folse, et al. (2003). Blueprints 2: Composition Skills for Academic Writing. Thomson/Heinle: Boston. 0-618-14410-2.
3. Mikulecky & Jeffries (2005). More Reading Power 2nd
. Pearson Ed/Longman: Boston. 0-13-061199-9.
4. Miller & Cohen. (2003). NorthStar Reading & Writing Advanced. 2nd
ed. Pearson Ed./Longman: Boston. 0201755750.
5. Oshima & Hogue (2007) Writing Academic English 3rd
ed. Pearson Ed./Longman: Boston. 0131523597
6. Sokolik, M. (2000). Tapestry Reading 4. Thomson/Heinle: Boston. 0838400604.
7. Sokolik, M. (2000). Tapestry Writing 4. Thomson/Heinle: Boston. 0838400450.
8. Wegmann & Knezevic (2002). Mosaic 2 Reading 4th
ed. McGraw-Hill: New York. 0-07-232964-5.
9. Wholey, M. (2007). Reading Matters 4. 2nd
ed. Thomson/Heinle: Boston. 061847515X.
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GANPAT UNIVERSITY
B. Pharm Semester-III Program Structure for B. Pharm Semester-III Program
Sr. No.
Course Code
Course Title Teaching Scheme Hrs/Week Type of Course
Theory Credit Weighted
Credit Point Practical Credit Weighted
Credit Point
01 3A01PHP Physical Pharmacy-II
3 3 10 X 3 = 30 3 1.5 10 X 1.5 = 15 Core
02 3A02PEN Pharmaceutical Engineering-II 3 3 10 X 3 = 30 2 1 10 X 1 = 10 Core
03 3A03PCO Pharmaceutical Chemistry-III (Organic Chemistry)
3 3 10 X 3 = 30 3 1.5 10 X 1.5 = 15 Core
04 3A04PAN Pharmaceutical Analysis-I
3 3 10 X 3 = 30 3 1.5 10 X 1.5 = 15 Core
05 3A05PPH Pathophysiology
2 2 10 X 2 = 20 - - - Core
06 3A06PCG Pharmacognosy-II
2 2 10X 2 = 20 3 1.5 10 X 1.5 = 15 Core
07 3B07DMG Disaster Management 3 3 10 X 3 = 30 - - - Common
Total 19 19 190 14 7 70
Total Credit 19+07 = 26 and Weighted Credit Point 190 + 70 = 260
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GANPAT UNIVERSITY
B. Pharm Semester-III Program
Teaching and Examination scheme for B. Pharm Semester-III Program
Sr. No
Course Code
Course Title
Teaching Scheme Hrs/Week
Total Hours Examination
Theory Practical Theory Practical Theory Practical Total Int Ext Int Ext 1 3A01PHP Physical Pharmacy-II
3 3 45 45 30 70 30 70 200
2 3A02PEN Pharmaceutical Engineering-II
3 2 45 30 30 70 30 70 200
3 3A03PCO Pharmaceutical Chemistry-III
(Organic Chemistry)
3 3 45 45 30 70 30 70 200
4 3A04PAN Pharmaceutical Analysis-I
3 3 45 45 30 70 30 70 200
5 3A05PPH Pathophysiology
2 - 30 - 30 70 - - 100
6 3A06PCG Pharmacognosy-II
2 3 30 45 30 70 30 70 200
7 3B07DMG Disaster Management 3 - 45 - 30 70 - - 100 Total 19 14 285 210 210 490 150 350 1200
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GANPAT UNIVERSITY B. Pharm. Semester- III
3A01PHP Physical Pharmacy-II
Theory (3 Hours / Week; 45 Hrs)
1. Solutions of nonelectrolytes 05 Concentration expressions, equivalent weights, ideal and real solutions,
colligative properties, molecular weight determination 2. Solutions of electrolytes 05 Properties of solutions of electrolytes, Arrhenius theory of electrolytic
dissociation, theory of strong electrolytes, coefficients for expressing colligative properties
3. Kinetics 10 Rates and orders of reactions, influence of temperature and other factors
on reaction rates, decompositions and stabilization of medicinal agents, accelerated stability analysis, ICH guidelines for stability study
4. Complexation and protein binding 07 Metal complexes, organic molecular complexes, Types of complexes – Inclusion
complexes, Techniques for characterization of complexes & their application protein binding
5. Polymer science 08 Clarification & fabrication technology, Pharmaceutical applications of polymers,
Characterization of polymers, polymers in drug delivery systems, general properties of polymer solutions, introduction to synthetic polymers used in pharmacy
6. Diffusion and dissolution 10 Theory of diffusions & dissolution procedure, Steady state diffusion, dissolution,
drug release
Practical (3 Hours/Week; 45 Hours) Practicals demonstrating any theoretical aspects of above topics may be carried out. Reference Books: 1. Martin’s Physical Pharmacy and Pharmaceutical Sciences by Patrick J. Sinko, 6th ed.,
Lippincott Williams & Wilkins, New York, 2010. 2. Aulton’s Pharmaceutics: The Design and Manufacture of Medicines, by Aulton,
Michael E., 3rd ed., Chrchill Livingstone, London, 2007 3. Remington: The Science and Practice of Pharmacy Remington by Remington,
21th ed., Lippincott W.W.,Philadelphia, 2009. 4. Physicochemical Principles of Pharmacy, 3rd ed., Florence, A. T. Atwood, D.
Macmillan Press Ltd., London, 1998.5. A Ansel’s Pharmaceutical Dosage forms and Drug delivery systems by Allen, Loyd V.,
9th ed., Walter Kluwer (India) Pvt. Ltd., New Delhi., 2009. 6. 7.
Cooper and Gunn’s Tutorial Pharmacy, edited by Carter, S. J., 6th ed., CBS Publishers &Distributors, New Delhi, 2000. Bentley’s textbook of Pharmaceutics by Rawlins, E.A., 8th ed., Elsevier I Pvt. Ltd., 2010.
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GANPAT UNIVERSITY B. Pharm. Semester- III
3A02PEN Pharmaceutical Engineering-II
Theory (3 Hours / Week; 45 Hrs)
1 Content uniformity 08 Importance of content uniformity, means of achieving content uniformity, Sampling
techniques, statistical treatment, requirements of regulatory agencies, (FDA, USP and European Pharmacopoeia)
2 Powder flow 09 Importance of flow in pharmacy, Factors influencing powder/granules flow
(moisture, particle size, etc.), Determination of angle of repose (AR),Hausner ratio (HR), Carr’s compressibility index (CI) , Sample calculations (examples), pharmacopoeial specifications for AR, HR and CI
3 Control charts and its applications in pharmacy 06 Elements of control charts and types of control charts, etc. 4 Extrusion and Pelletization 10 Factgors affecting pellet properties, Cold extrusion, Melt extrusion,Applications of
extrusion in pharmacy (including preparation of solid solution), selective quipments used for extrusion and pelletization, Use of polyethylene oxide and Eudragit in melt extrusion, Use of MCC in pelletization
5 Supercritical fluids 10 Introduction to supercritical fluids, Pharmaceutical applications of supercritical
fluids in extraction, size reduction, preparation of inclusion complexes, preparation of solid dispersions, equipments etc.,
Practical (3Hours/Week; 45 Hours)
Practicals related to topics in pharmaceutical engineering theory should be carried out. Note: 1. Calculations shall be performed in EXCEL
2. Graphs shall be drawn using EXCEL Reference Books:
1 Perry’s Chemical Engineer’s Handbook by Robert H Perry, Green D.W., Maloney J. O.
8th ed., McGraw – Hill Inc., New Delhi, 2007. 2 Cooper and Gunn’s Tutorial Pharmacy, edited by Carter, S. J., 6th ed., CBS Publishers &
Distributors, New Delhi, 2000. 3 Aulton’s Pharmaceutics: The Design and Manufacture of Medicines, by Aulton,
Michael E., 3rd ed., Chrchill Livingstone, London, 2007. 4 The Theory & Practice of Industrial Pharmacy by Lachman Leon, 3rd ed., CBS
Publishers & Distributors, New Delhi, 2009 5 Remington: The science and practice of pharmacy Remington by Reminston, 21th
ed., Lippincott W.W.,Philadelphia, 2009. 6 Pharmacopoeia : I.P., U. S. P., E.P
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GANPAT UNIVERSITY B. Pharm. Semester- III
3A03PCO Pharmaceutical Chemistry-III (Organic Chemistry)
Theory (3 Hours / Week; 45 Hrs)
1. Structure and Properties 12 Introduction to organic chemistry, quantitative analysis of elements, determination
of molecular weight and molecular formula, Atomic structure, atomic orbitals, wave equation, molecular orbital theory, molecular orbitals, bonding and antibonding orbitals.
2. Chemical bonding and Properties 12 Introduction, covalent bond, hybridization and hybrid orbitals, intermolecular and
intramolecular forces, bond dissociation energy, electronegativity, polarity of bonds, polarity of molecules, resonance, hyperconjugation, acids and bases
3. Reactive intermediates of carbon 04 Carbocation, carbanion, free radical, carbenes, nitrenes and nitrinium ions, reaction
involving these intermediates. 4. Structure, properties, nomenclature, preparation and reactions of the following class
of functional groups Alkanes, alkenes, alkynes, dienes, cycloalkanes, alkyl halides, alcohols, ethers, epoxides.
11
5. Electrocyclic cycloaddition and sigmatropic reactions, neighboring group effects, catalysis by transition.
06
Practicals (3 Hours/Week; 45 Hours) Systematic qualitative analysis of organic compounds and preparation of their derivatives. (Organic compounds of all types of functional groups) Reference Books: 1. Organic Chemistry, Robert T. Morrison and Robert N. Boyd, 6th ed., PH I Learning
Pvt. Ltd., New Delhi, 2008 2. Organic Chemistry by G. Marc Loudon, 4th ed., Oxford University Press, 2004. 3. Organic Chemistry, Vol I and II by I. L. Finar, 6th ed., Pearson Education, New Delhi
2000. 4. Advanced Organic Chemistry, by Jerry March, 4th ed., Wiley India, 2007. 5. Vogel’s textbook of practical organic chemistry, by Furniss, Brain S., 5th ed., Pearson
Education, Delhi, 2005. 6. Experimental Organic Chemistry by L. M. Harwood, L. J. Moody, J. M. Percy, 2nd
Edition, Blackwell Science, 2005.7. Techniques and Experiment of Organic Chemistry, Addison Ault, 6th Edition,
University Science Books, 1998. 8. Introduction to Organic Laboratory Techniques, A Microscale Approach, Donald L.
Pavia, Gary M. Lampman, 4th ed., Harcourt College Pub., 2007.
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GANPAT UNIVERSITY B. Pharm. Semester- III
3A04PAN Pharmaceutical Analysis-I
Theory (3 Hours / Week; 45 Hrs) 1 Basics of drugs and formulation analysis 06 weights, balances, importance of analysis, accuracy and precision,
analytical methods (classification), chemicals (types, purification, checking purity), glasswares (types, calibration, cleaning), sampling techniques, sampling error minimization. Units of concentrations. Errors science, errors minimization.
2 Volumetric analysis: Titrimetric analysis Acid-base titrations:
Relative strength and its effect on titration, common ion effect, pH, Henderson-Hesselbach equation, buffers, neutralization curve, acid base indicators, theory of indicators, back titrations, biphasic titrations,pharmacopoeial applications, hydrolysis of salts, ionic products of water and law of mass action. Redox titrations: Theory of redox titrations, redox indicators, types of redox titrations, iodometry, cerrimetry, mercury metry, diazotization nitrite titrations, 2,6-dichlorophenol indophenol titrations, titration curve and calculations of potentials during course of titrations. Precipitation titrations : Precipitation reactions, Solubility Products, Effect of acid, temperature and solvents upon solubility of precipitates Nonaqueous titrations : Nonaqueous solvents, titrants and indicators. Differentiating and leveling solvents. Complexometric titrations : Theory of the titrations, titrant, indicators and pharmacopoeial applications. Karl-Fischer titrations:
08
07
04
02
04 03
3 Gravimetric analysis 03 Stability, solubility products, types of precipitations, precipitation techniques,
pharmacopoeial applications. 4 Extraction techniques 5 Simple extraction, multiple extractions, separation of drugs in multicomponent
system. Effect of pH on extractability of drugs, continuous extractions. 5 Miscellaneous methods 2 Oxygen combustion flask method, Kjeldahl method and gasometric method, etc. 3
Practicals (3 Hours/Week; 45 Hours) 1. Acid-base titrations: Simple, back titrations, titrations of mixtures like NaOH + Na2CO3, borax + boric acid. 2. Redox titrations: Simple, iodometry, cerrimetry, 2,6-dichlorophenol-indophenol titrations, mixtures like Fe+2 + Fe+3, oxalic acid + sodium oxalate 3. Complexometric titrations: Replacement, back titrations 4. Nonaqueous titrations 5. Argentometric titrations 6. Gravimetric assay of one pharmacopoeial drug 7. Calibrations/cleaning of glasswares and checking precision and lower limit of quantitaiton of titrimetric method
7
Reference Books: 1. Pharmacopoeia: USP, B.P., I.P. 2. Practical Pharmaceutical Chemistry, Vol. I & II by Backett, A. H.,1st ed., CBS
Publishers & Distrubuters, New Delhi, 1997.3. Fundamentals of Analytical Chemistry by Skoog, Douglas A., 8th ed., Harcourt College
Publishers, 2004 4. Quantitative chemical analysis by Vogel A. I., 6th ed., Pearson Education, 2000 5. Text Book of Pharmaceutical Analysis by K. A. Connor, 3rd ed., John Willey &
Sons,Delhi, 2009. 6. Quantitative Chemical Analysis by Gilbert H. Ayres, 2nd Ed. Harper & Row, Ltd, New
York, 1968
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GANPAT UNIVERSITY B. Pharm. Semester- III
3A05PPH Pathophysiology
Theory (2 Hours / Week; 30 Hrs) 1 Basic principles of cell injury, cell death and adaptation 08 Causes, pathogenesis and morphology of cell injury, Apoptosis-causes and
mechanism, intracellular alteration in lipids, proteins and carbohydrates, (abnormalities of lipoproteinemia, glycogen infiltration, and glycogen storage diseases) calcification, cellular adaptations-Atrophy, hypertrophy, metaplasia and hyperplasia
2 Inflammation 03 Basic mechanism involved in the process of inflammation, pathogenesis of acute
and chronic inflammation, chemical mediators of inflammation. 3 Tissue repair processes 03 Control of cell proliferation, Growth factors and extra cellular matrix, Cell and
tissue regeneration, repairs of wound in skin, pathological aspects of repair 4 Diseases of the immune system 09 Introduction, Hypersensitivity(type I,II,III,IV with examples of diseases), allergy
due to food, chemicals, drugs; Autoimmunity (Immunological tolerance, mechanism of autoimmunity); transplantation and mechanism of allograft rejection; Autoimmune diseases (Systemic Lupus erythematosus, Rheumatoid arthritis, Systemic sclerosis, Inflammatory myopathies, Mixed connective tissue disease, polyarteritis nodosa and other vasculitides), AIDS, Amylodosis.
5 . Environmental and nutritional diseases 05 Air pollution and smoking, SO2, NO, NO2 and CO; protein calorie malnutrition,
pathogenesis of starvation, vitamins, obesity. 6 Biological effects of radiation 02
Reference Books: 1. Robbin’s Pathologic basis of disease by- Cotran, Kumar, Robbins, 7th ed.,
W.B.Saunders, 2004 2. Text book of Pathologyby Harsh Mohan, 4th ed., Jaypee Brothers, New Delhi, 2002 3. Text book of Pathology- Y. M. Bhinde
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GANPAT UNIVERSITY B. Pharm. Semester- III
3A06PCG Pharmacognosy-II Theory (2 Hours / Week; 30 Hrs) 1 Resins :
Introduction, Study of drugs containing resins and resins combination like Podophyllum, Jalap, Capsicum, Myrrh, Asafetida, Benzoin, Turmeric, Ginger.
7
2 Tannins : Introduction, Study of tannins containing drugs like Gambir, Black catechu, Myrobalan, Gall
5
3 Volatile Oils : Introduction including General methods of obtaining volatile oils from plants, Study of crude drugs and volatile oils of Fennel, Cumin, Caraway, Dill, Coriander, Cinnamon, Cassia, Cardamom, Clove, Mentha, Eucalyptus, Lemon peel, Lemon grass, Nutmeg, Chenopodium, Valerian, Sandal wood.
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4 Phytochemical Screening : 4.1 Preparation of extracts 4.2 Screening of alkaloids, saponins, cardenolides and bufadienolides, flavonoids and leucoanthocyanidins, tannins and polyphenols, anthraquinones, cynogenetic glycosides, amino acids in plant extracts
2
5 Fibres : Study of fibers used in pharmacy such as cotton, silk, wool, nylon.
3
6 Pharmaceutical aids: Study of pharmaceutical aids like talc, diatomite, gelatin and natural colors.
3
Practical (3hrs/Week; 45Hours) 1. Identification of crude drugs mentioned in theory (morphology and chemical tests.) 2. Study of fibers and pharmaceutical aids. 3. Microscopic studies of seven from nine underlined crude drugs and their powders mentioned under the category of volatile oils in theory and their chemicals tests. 4. General chemical tests for alkaloids, glycosides, steroids, flavonoids and tannins. Reference Books: 1. Trease and Evans Pharmacognosy by Evans William Charles, 16th ed., Saunders Elsevier,
Newyork, 2009. 2. Pharmacognosy by V. E. Tyler, 9th ed., Lea and Febiger, Philadelphia,, 1988. 3. A Text book of Pharmacognosy by Quadry, J. S.. 16th ed., CBS Publishers &
Distrubuters, New Delhi, 2010. 4. Textbook of Pharmacognosy by T. E. Wallis, 5th ed., CBS Publishers & Distrubuters,
New Delhi, 2005. 5. A Textbook of Pharmacognosy by T. C. Denston, 5th Edition, Pitman Medical Publishing
Co. Ltd., London. 6. Recent Progress in Medicinal Plants, Vol 4, Biotechnology and Genetic Engineering. J.
N. Govil, P. Ananda Kumar, V. K. Singh, Studium Press, LIC, Texas, 2002. 7 Modern Pharmacognosy by Egil Ramstad,: Blackiston Division, McGraw-Hill, New
York, 1959 8 The Organic Constituents of Higher Plants. Their chemistry and interrelationships. By
Trevor Robinson, Burges Publishing Company, Minneapolis, USA, 1963. 9 Pharmacognosy: Phytochemistry Medicinal Plants.by Jean Bruneton, 2nd ed., TEC &
DOC Paris, 1999
10
GANPAT UNIVERSITY B.PHARM. SEMESTER – III
3B07DMG DISASTER MANAGEMENT Theory: 45 hours (3 hours/week; 3 credit) 1 NATURAL DISASTERS 10 1.1 Types of natural disaster
a) Cyclone b) Flood c) Fire d) Desert storms e) Land slides f) Snow avalanches
1.2 Cyclone a) Introduction b) Fundamentals c) Characteristics d) Causes & effects e) Preventive and Remedial measures
1.3 Flood a) Introduction b) Fundamentals c) Causes and effects d) Preventive and Remedial measures
1.4 Fire a) Fundamentals b) Causes & effects
c)Preventive and remedial measures 2 FUNDAMENTALS OF SEISMIC ENGINEERING 06 2.1 Introduction
a) Definition b) History of earthquake c) Earth and its’ structure
2.2 Terminology a) Epicenter b) Hypocenter c) Focus d) Epicenter distance
2.3 Waves generated due to earthquake a) P waves b) S waves
2.4 Causes of earthquake 2.5 Measurement of earthquake
a) Intensity and magnitude of earthquake b) Sysmo-graph c) Sysmo-scope d) Sysmo-meter e) Richter scale
2.6 Zoning of earthquake as per I.S.
11
2.7 Effects of earthquake on a) Soil b) Low-rise and high-rise buildings c) Human psychology d) Communication e) Geology
2.8 General instructions for protection of people during earthquake 2.9 General guidelines for construction and maintenance of earthquake proof/resistant masonry structure
3 MAN MADE DISASTERS 16 a) War and Terrorism,
b) Riots and Demonstrations, c) Residential and Industrial d) Fires, e) Transportation Accidents, f) Nuclear Power Accidents, g) Hazardous Materials and Toxic Emission, h) Utility Failure.
4 Problems regarding victims and its awareness 07 a) Saving Victims – First Twenty-Four Hours,
b) Conducting Medical Relief Operations, c) Managing Relief Operations, d) Psychological Issues, e) CarryingOut Rehabilitation Work
5 Planning for disaster management 06 a) Local Disaster Management Cell,
b) How to Prepare a Business Recovery Plan?, c) Government Response in Disaster.
NOTE: It is necessary to include mock drill, field visit and expert lectures in the portion of Disaster Management. The format of the question paper in the portion of Disaster Management should be objective with short answer questions, multiple choice questions etc. References Books: 1. Disaster Management By G.K. Ghosh, A.P.H. Publishing Corporation, 2006 2. Disaster Management By R.B. Singh, Rawat Publications, 2000 3. Disaster Management: Through the New Millennium By Ayaz Ahmad, Anmol Publications 4. Emergency Medical Services and Disaster Management: A Holistic Approach By P.K. Dave
Jaypee Brothers Medical Publishers (P) Ltd, 2001 5. Disaster Management By B Narayan, A.P.H. Publishing Corporation, 2004 6. Modern Encyclopaedia of Disaster and Hazard Management By B C Bose, Rajat
Publications, 2009 7 Disaster Management By Nikuj Kumar, Alfa Publications, 2006 8 Disaster Management - Recent Approaches By Arvind Kumar, Anmol Publications, 2006 9 Tsunamis: Threats and Management by Dr. Jagbir Singh , I.K. International, 2009 10 Disaster Management Future Challenges and Opportunities by Dr. Jagbir Singh. , I.K.
International, 2007 11 Citizen’s guide to disaster management by Satish Modh Publisher:-Macmillan Publishers
India, 2006 12 Environment and Sesmic Engineering By Atul Prakashan Ahmedabad, 2008
1
GANPAT UNIVERSITY
B. Pharm Semester-IV Program
Structure for B. Pharm Semester-IV Program
Sr.
No.
Course
Code
Course Title
Teaching Scheme Hrs/Week Type of Course
Theory Credit Weighted
Credit Point
Practical Credit Weighted
Credit
Point
01 4A01DPH Dispensing Pharmacy-I
3 3 10 X 3 = 30 2 1.0 10 X 1.0 = 10
Core
02 4A02FPH Forensic Pharmacy
3 3 10 X 3 = 30 - - -
Core
03 4A03PCO Pharmaceutical Chemistry-IV (Organic Chemistry)
3 3 10 X 3 = 30 3 1.5 10 X 1.5 = 15
Core
04 4A04PAN Pharmaceutical Analysis-II
3 3 10 X 3 = 30 3 1.5 10 X 1.5 = 15 Core
05 4A05PCL Pharmacology-I
2 2 10 X 2 = 20 3 1.5 10 X 1.5 = 15 Core
06 4A06PCG Pharmacognosy-III
2 2 10X 2 = 20 3 1.5 10 X 1.5 = 15 Core
07 4B07EPC Environment and Pollution
Control
3 3 10 X 3 = 30 - - -
Common
Total 19 19 190 14 7.0 70
Total Credit 19+7.0 = 26 and Weighted Credit Point 190 + 70 = 260
2
GANPAT UNIVERSITY
B. Pharm Semester-IV Program
Teaching and Examination scheme for B. Pharm Semester-IV Program
Sr.
No
Course
Code
Course Title
Teaching Scheme
Hrs/Week
Total Hours Examination
Theory Practical Theory Practical Theory Practical Total
Int Ext Int Ext
1 4A01DPH Dispensing Pharmacy-I
3 2 45 30 30 70 30 70 200
2 4A02FPH Forensic Pharmacy
3 - 45 - 30 70 - - 100
3 4A03PCO Pharmaceutical Chemistry-
IV
(Organic Chemistry)
3 3 45 45 30 70 30 70 200
4 4A04PAN Pharmaceutical Analysis-II
3 3 45 45 30 70 30 70 200
5 4A05PCL Pharmacology-I
2 3 30 45 30 70 30 70 200
6 4A06PCG Pharmacognosy-III
2 3 30 45 30 70 30 70 200
7 4B07EPC Environment and Pollution
Control
3 - 45 - 30 70 - - 100
Total 19 14 285 210 210 490 150 350 1200
3
GANPAT UNIVERSITY B. Pharm. Semester- IV
4A01DPH Dispensing Pharmacy-I
Theory: (3 Hours / Week; 45 Hrs) Credit:3
Practical (2 Hours/week; 30 Hours) Credit: 1
The students shall be asked to perform the practical related to the topics mentioned under
theory.
Reference Books:
1. Pharmaceutical Practice by Diana M. Collett and Michale E. Aulton, ELBS
Publishers
2. Dispensing Pharmaceutical for students by Cooper and Gunn, 12th
ed. CBS
Publishers & Distrubuters,New Delhi, 2000.
3. Pharmaceutical Calculations by Ansel ,Howard C.,13th
ed., Walter Kluwer (India)
Pvt. Ltd., New Delhi., 2009.
4. Ansel’s Pharmaceutical Dosage forms and Drug delivery systems by Allen, Loyd V.,
9th
ed., Walter Kluwer (India) Pvt. Ltd., New Delhi., 2009.
5. Pharmaceutical Practice, Edited by A.J. Winfield and R.M.E. Richards, 3rd
ed.,
Edinburgh : Churchill Livingstone, 2004
6. Hospital pharmacy by Hassan, Henry, 5th
ed.,Lea & Febiger, Philadelphia, 1986
7. Hospital Organization and management by Kurt Dan and Jonathan S. Ratich, 4th
ed.
CBS Publishers
8. Remington: The science and practice of Pharmacy Remington by Reminston, 21th
ed. Lippincott W. W.,Philadelphia, 2009
1. Definition and scope, Sources of information required by pharmacist 01
2. The prescription: Handling of prescription, source of errors in prescription,
care, required in dispensing procedures including labelling at dispensed
products
04
3. Dispensing techniques: Compounding and dispensing procedures,
packaging, storage and stability of medicines, labeling of dispensed products.
05
4. Pharmaceutical calculations: Posology and metrology: Calculations of doses
for infants, adults and elderly patients, enlarging and reducing recipes,
percentage solutions, allegation, alcohol dilution, proof spirit, isotonic
solutions, displacement values, etc
15
5. Principles involved and procedures adopted in dispensing of:
Mixtures, Solutions like simple solutions, draughts, drops, linctus, syrups,
elixirs, suspensions, emulsions, etc., Powders/granules for oral use; oral unit
dosage forms like tablets, capsules, lozenges, pestilles etc., Inhalations.
20
4
GANPAT UNIVERSITY B. Pharm. Semester- IV
4A02FPH Forensic Pharmacy Theory(3 Hours / Week; 45 Hrs) Credit:3
Reference Books:
1. A text Book of Forensic Pharmacy by- N.K.Jain
2. A text Book of Forensic Pharmacy by- B.M.Mithal
3. A text Book of Forensic Pharmacy by- G.K.Jani.
4. The Drugs & Cosmetics Act 1940 & rules-1945-By Vijay Malik
5. Latest Governments Publications Regarding Specific Law
6. Drug and Cosmetic act and Rules by Vijay Malik
1. Pharmaceutical Legislation in India-brief review. 01
2. Drug & Pharmaceutical industries in India- brief review. 01
3. Pharmaceutical education in India- brief review. 01
4. Pharmaceutical Ethics:
Principles and significance of professional Ethics. Critical study of the Code of
Pharmaceutical Ethics drafted by Pharmacy Council of India. Pharmacist’s oath.
02
5. Pharmacy Act 1948: Objective of the Act , Definitions, Pharmacy Education Regulations. Working of State
and Central Councils, Constitution & functions of Councils. Registration procedures
for Pharmacist under the Act and its renewal. Offence & Penalties.
06
6. Drug and Cosmetic act 10
7. Medicinal & Toilet Preparations [Excise Duties] Act1955 Objective, definitions, licensing procedures for manufacturing of different preparation
in bonded and non-bonded laboratory, Offences & Penalties.
03
8. Narcotic Drugs & Psychotropic Substance Act 1985 & Rules
Objective, definitions, constitution and functions of narcotic and psychotropic
consultative committee, national fund for controlling the drug abuse, prohibition,
control and regulation for import, manufacture and transshipments of these drugs.
Power of Inspector. Offences and Penalties.
04
9. Drug Price Control Order 1995 General study of the order with its Objectives, Definitions, Fixation price of bulk drugs
and retail price of formulations. Powers of Central Govt. Records to be maintain.
DPEA. Offence & Penalties.
03
10. Prevention of cruelty to Animals Act 1960.
Objectives, definitions and provisions of Act like constitution of committee. Breeding
of animals, maintenance of records. Detail of forms.
03
11. States shops & Establishment Act 1960.
Introduction, objectives, definitions and provisions of Act like registration of
establishment, hours of work, wages, appointment, inspection, offences and penalties.
03
12. Factories Act 1948. Introduction, objectives, definition and provisions of Act like licensing procedure,
health, safety & welfare of workers, working hours, employment of women and young
children, leaves. Offences and Penalties.
03
13. Drug and Magic Remedy act, Medical Termination of Pregnancy 03
14. Drug Policy 2002 02
5
GANPAT UNIVERSITY
B. Pharm. Semester- IV 4A03PCO Pharmaceutical Chemistry-IV
(Organic Chemistry)
Theory: (3 Hours / Week; 45 Hrs) Credit: 3
Practical (3 hr/week; 45 Hours) Credit:1.5
1. Qualitative analysis of unknown organic compound.
2. Introduction and detailed demonstration to various synthetic techniques and
apparatus used therein. Heating and cooling methods, distillation, reaction work-up,
filtration, extraction, purification, identification.
3. Synthesis of selected organic compounds
Synthesis of selected compounds based on various reaction mechanisms like
halogenation, nitration, alkylation, hydrolysis, oxidation, condensation,
diazotization. Purification of the synthesized compound using precipitation or
recrystallization. Monitoring progress of reaction by thin layer chromatography.
4. Introduction to the use of stereomodels
Reference Books:
1. Organic Chemistry, Robert T. Morrison and Robert N. Boyd, 6th
ed., PH I Learning
Pvt. Ltd., New Delhi, 2008
2. Organic Chemistry by G. Marc Loudon, 4th
ed., Oxford University Press, 2004.
3. Organic Chemistry, Vol I and II by I. L. Finar, 6th
ed., Pearson Education, New
Delhi 2000.
4. Advanced Organic Chemistry, by Jerry March, 4th
ed., Wiley India, 2007.
5. Vogel’s textbook of practical organic chemistry, by Furniss, Brain S., 5th ed.,
Pearson Education, Delhi, 2005
6. Experimental Organic Chemistry : Standard and Microscale by L. M. Harwood, 2nd
ed., Blackwell Science, 1991.
7. Techniques and Experiment of Organic Chemistry, Addison Ault, 6th
Edition,
University Science Books, 1998.
8. Introduction to Organic Laboratory Techniques, A Microscale Approach, Donald L.
Pavia, Gary M. Lampman, George S. Kriz, 4th
ed., Thomson Books, 2006.
1. Stereochemistry 10
Chirality, optical activity, stereoisomerism, nomenclature and associated
physicochemical properties, specification of configuration, resolution of
racemic mixture, reactions involving stereoisomers, stereoselective and
stereospecific reactions, conformations – alkanes and cycloalkanes, chiral
reagents, stereochemistry of biphenyls, allenes, and spirans – specification of
their configuration
2. Structure, properties, nomenclature, preparation and reactions of the following
class of functional groups
Benzene, polynuclear aromatic compounds, arenes, amines, phenols, aldehydes
and ketones, carboxylic acids and their derivatives.
28
3. α,β-unsaturated carbonyl compounds, conservation of orbital symmetry and
rules, Nucelophilic aromatic substitution
04
4. Introduction to nanochemistry, microwave synthesis and green chemistry. 03
6
GANPAT UNIVERSITY B. Pharm. Semester- IV
4A04PAN Pharmaceutical Analysis-II
Theory: (3 Hours / Week; 45 Hrs) Credit:3.0
.
Practical (3 hr/week; 45 Hours) Credit:1.5
Quantitative analysis of different compounds involving techniques such as
Conductometry, Potentiometry, pH metry, Polarimetry, Column chromatography, Thin
layer chromatography, Paper chromatography and Karl – Fischer titration
Reference Books:
1. Pharmacopoeia: USP, B.P., I.P.
2. Practical Pharmaceutical Chemistry, Vol. I & II by Backett, A. H., 1st ed., CBS
Publishers & Distrubuters,New Delhi,1997.
3. Pharmaceutical Analysis Part I & II by J. W. Munson, International Medical Book
Dist., Mumbai, 2001
4. Fundamentals of Analytical Chemistry by Skoog, Douglas A., 8th
ed., Harcourt
College Publishers, 2004
5. Quantitative chemical analysis by Mendham,J. 6th
ed., Pearson Education, New
Delhi, 2009
6. Text Book of Pharmaceutical Analysis by K. A. Connor, 3rd
ed., John Willey &
Sons, Delhi, 2009.
7. Instrumental method of analysis by Willard Hobartb H., 7th
ed., CBS Publishers &
Distrubuters, New Delhi, 1986.
Following topics should be covered with due consideration of pharmacopoeial
applications and numerical
1. Basics of instrumental analytical methods: Advantages and limitations. 03
2. Chromatography: Classification, theories, retention mechanism, separation
efficiency, methodology and pharmacopoeial applications of column, paper
and thin layer chromatography.
12
3. Electroanalytical methods: Basics of electroanalytical methods. 03
3.1 Conductometry: Conductance, factors affecting conductance, Kohlrausch law,
conductivity cells, applications.
05
3.2 Potentio and pH metric methods: Standard reduction potentials, various
electrodes, electrodes and cell potential, applications of potentiometry and pH
metry.
06
3.3 Polarography, amperometry, biamperometry: Basics of current flow in
polarography, dropping mercury electrode, diffusion current, half wave
potential, modifications like pulsed and differential pulse polarography,
stripping voltametry, biamperometric titrations, amperometric titrations
09
4. Calorimetry: Types, thermogravimetric analysis, differential scanning
calorimetry, differential thermal analysis, melting point, etc. and their
applications.
05
5. Polarimetry: Polarimeter, qualitative and quantitative applications. 02
7
GANPAT UNIVERSITY B. Pharm. Semester- IV
4A05PCL Pharmacology-I
Theory: (2 Hours / Week; 30 Hrs) Credit: 2
Practical (3 hrs/week; 45 Hours) Credit: 1.5
1. Introduction to experimental pharmacology: preparation of different solutions for experiments.
Drug dilutions, use of molar and W/V solutions in experimental pharmacology, common
laboratory animals, Legal regulations for the use of experimental animals, anesthetics and
instruments commonly used in experimental pharmacology. Some common and standard
techniques for drug administration (intravenous injection, intra gastric administration) and
collection of blood samples. Euthanasia of laboratory animals.
2. Experiments on urinary excretion of drugs/their metabolites
3. To study the effects of various agonists (pD2) and antagonist (pA2) using isolated preparations,
To record the concentration response curve (CRC) of acetylcholine using rat ileum/chicken
preparation, To study the effect of atropine on concentration response curve (CRC) of
acetylcholine using rat/chicken ileum preparation, To record the concentration response curve
(CRC) of Histamine on guinea pig/chicken ileum, To study the effect of mepyramine on
concentration response curve (CRC) of Histamine using guinea pig /chicken ileum preparation
4. To study the effects of acetylcholine, Histamine, BaCl2, physostigmine, atropine, mepyramine
and papaverine using rat/guinea pig/chicken ileum preparation
5. Demonstration Experiments on study the effects of autonomic drugs on rabbits eye, study the
effect of hepatic microsomal enzyme inhibitors and inducers on pentobarbitone sleeping time,
study the effects of various drugs on rat fundus preparation, study the effects of various drugs on
rat anococcygeus muscle preparations and to study the effects of various drugs on rat.
Reference Books:
1. Pharmacology and pharmacotherapeutics. 21st ed., Popular Prakashan, Mumbai, 2010.
2. Rang, H.P. & Dale, M.M., Pharmacology. 6th
ed., Churchill Living stone, London, 2007
3. Goodman & Gilman’s, The Pharmacological basis of therapeutics. Mcgrawhil, New Delhi, 2005
4. Basic and clinical pharmacology by Katzung, B.G., 11th
ed., Mc graw Hill, New Delhi, 2009.
5. Fundamentals of exp pharmacology by Ghosh, M.N., 4th
ed., Hilton & Company, Kolkatta, 2008.
6. Practicals in Pharmacology by R. K. Goyal, 9th
ed., B.S. Shah Prakashan, Ahmedabad, 2010.
1. General pharmacology 16
Introduction and scope of pharmacology, Sources of drugs and nomenclature of drugs,
Dosage forms and routes of administration, Factors modifying drug action, tolerance and
dependence, Phrmacokinetics: Drug absorption and bio-avaibility of a drug Distribution,
Biological half life and its significance, drug distribution, drug metabolism, drug excretion,
Methods prolonging the duration of action of a drug, Pharmacodynamics: Mechanism of
drug action, site of drug action, drug receptors, dose response relationship, combined effects
of drugs, structure activity relationship, Adverse drug Reactions, Drug interactions, New
Drug Development: Acute, sub-acute and chronic animal Toxicity study, clinical trials
2. Pharmacology of Peripheral Nervous system 09
Neurohumoral transmission (autonomic and somatic), Parasympathomimetics, Parasym-
patholytics, Sympathomimetics, adrenergic receptor and neuron blocking agents, Ganglionic
stimulants and blocking agents Neuromuscular blocking agents, Local anesthetics
3. Autacoids 05
a. Histamine, 5-HT and their antagonists. b. Prostanglandins, thromboxane and leukotrienes.
c. Pentagastrin, cholecystokinin, Angiotensin, Bradykinin and substance P
8
GANPAT UNIVERSITY B. Pharm. Semester- IV
4A06PCG Pharmacognosy-III
Theory: (2 Hours / Week; 30 Hrs) Credit:2
Practicals (3 Hours/week; 45 Hours) Credit:1.5
1. Identification of crude drugs listed in theory.
2. Microscopic study of underlined important glycoside containing crude drugs.
Reference Books:
1. Trease and Evans Pharmacognosy by Evans William Charles, 16th
ed., Saunders
Elsevier, Newyork, 2009.
2. Pharmacognosy by V. E. Tyler, 9th
ed., Lea and Febiger, Philadelphia, 1988.
3. A Text book of Pharmacognosy by Quadry, J. S. 16th
ed., CBS Publishers &
Distrubuters, New Delhi, 2010.
4. Textbook of Pharmacognosy by T. E. Wallis, 5th
ed., CBS Publishers &
Distrubuters, New Delhi, 2005.
5. A Textbook of Pharmacognosy. by T. C. Denston, 5th
Edition, Pitman Medical
Publishing Co. Ltd., London, 1958.
6. Modern Pharmacognosy by Egil Ramstad,: Blackiston Division, McGraw-Hill, New
York, 1959
7. Text book of Pharmacogonosy by Heber W. Youngken, 6th
ed., The Blakiston
Company, Toronto, 1948
8. Pharmacognosy: Phytochemistry Medicinal Plants by Jean Bruneton, 2nd ed., TEC
& DOC Paris, 1999
9. Laboratory Handbook for the fractionationation of Nattutal extracts by Peter
Houghton and Amala Raman, Springer, 2011.
10. Cultivation and Utilization of Aromatic Plants, Handa S. S. and Kaul M. K.,
Jammu-Tawi Regional Research Laboratory, Council of Scientific & Industrial
Research, 1997
11. Cultivation and Utilization of Aromatic Plants by Atal C. K., CSIR, Jammu, 1982.
1. Study of the biological sources, cultivation, collection, commercial varieties,
chemical constituents, substitutes, adulterants, uses, diagnostic macroscopic and
microscopic features and specific chemical tests of following groups of drugs
containing glycosides:
22
Saponins: Liquorice, ginseng, dioscorea, Senega, Sarsaparila, Quillaia
Cardioactive sterols: Digitalis, squill, strophanthus, Thevetia
Anthraquinone cathartics: Aloe, senna, rhubarb, cascara, Cassia
iv. Bitter glycosides: Gentian, picrorrhiza, chirata, kalmegh, Quassia
Coumarins: Psoralea, Ammi majus, Ammi visnaga
Cyanogenetic glycosides: Almond, Linseed
Isothiocyanate glycosides:Mustard, Black mustard
Flavanoids: Rutagraveolens
2. Enzymes: Biological sources, preparation, identification test and uses of
following Diastase, Papain, Pepsin, Trypsin, Pancreatin
08
9
GANPAT UNIVERSITY
B.Pharm Semester – IV
4B07EPC Environment and Pollution Control
Theory: 45 hours (3 hours/week) Credit:3
Reference Books:
1. Handbook of industrial pollution and control vol. 1 by S.C. Bhatia CBS Publishers &
Distributors, New Delhi, 2002
2. Air Pollution by Rao and Rao, Mcgraw hill, Europe, 1989
3. Environmental Engineering by Panday and Carney TMH New Delhi
4. Introduction to Environmental Engineering and science by Gilber M Masters, 3rd
ed., Doeling
Kindersley , New delhi,2008
5. Environment and Sesmic Engineering By Atul Prakashan Ahmedabad.
1. INTRODUCTION 1
Environment & its components, Environment in India, Public awareness
2. ECOLOGICAL ASPECTS OF ENVIRONMENT 6
Ecology, Eco system, Factors affecting Eco system, Elton pyramid, Biogeochemical
cycles (Hydrologic cycle, Carbon cycle, Nitrogen cycle, Phosphorus cycle, Sulphur
cycle), Biodiversity, Future of human being
3. NATURAL RESOURCES 7
Types of natural resources, Quality of life, Population and Environment, Water
resources, Population projection methods (Arithmetic progression method, Geometric
progression method, Incremental Increase method, Logistic curve method, Declining
growth method, Water demand, Forest as resource, Forest and Environment,
Deforestation, Afforestation, Forest conservation, its methods, Land, Uses and abuses of
waste and wet land, Other resources, Oil and mineral resources, their depletion and
effects
4. GLOBAL ENVIRONMENTAL PROBLEMS 6
Major Global problems, Acid rain, Green house effect, Depletion of Ozone layer,
Human predictiments, Introduction of global warming, Measures against global
worming
5. ENVIRONMENTAL POLLUTION 12
Water pollution, Characteristics of domestic waste water, Principles of treatment, Water
treatment plant, Air pollution, Pollutants, Sources of pollution, Effect of pollutants, Air
monitoring system, Air pollution control, Noise pollution, Acoustic treatment for noise
pollution, Place of noise pollution, Effect of noise pollution, Radio active pollution,
Radiation, Adverse effects of radiation & thermal pollution
6. CLEAN TECHNOLOGIES 7
Clean technology, Types of Energy, Conventional Energy Sources, Non-conventional
Sources of Energy, Recycling pollution control, Types of Pesticides, Integrated Pest
Management.
7. Water Quality Standards for industrial use (Pharmaceutical Industry) 2
8. Pollution Control in Pharmaceutical Industries 2
9. Recycling and reuse of liquid and solid industrial waste in Pharmaceutical
industries
2
GANPAT UNIVERSITY
B. Pharm Semester-V Program
Structure for B.Pharm Semester-V Program
Sr.
No.
Course
Code Course Title
Teaching Scheme Hrs/ week Type of
Course
Theo
ry Credit
Weighted
Credit
Point
Practic
al Credit
Weighte
d Credit
Point
01 5A01
HCP
Hospital & Community
Pharmacy 2 2
10 X2 =
20 -- -- -- Core
02 5A02
PMB
Pharmaceutical Microbiology 3 3
10 X 3 =
30 2 1.0
10 X1.0
= 10 Core
03 5A03
PCB
Pharmaceutical Chemistry-V
(Biochemistry-I) 2 2
10 X 2 =
20 3 1.5
10 X1.5
=15 Core
04 5A04
PCM
Pharmaceutical Chemistry-VI
(Medicinal Chemistry-I) 3 3
10 X 3 =
30 3 1.5
10X1.5
= 15 Core
05 5A05
PCG
Pharmacognosy-IV
3 3
10 X 3 =
30 3 1.5
10 X1.5
=15 Core
06 5A06
PCL
Pharmacology- II 3 3
10 X 3 =
30 3 1.5
10X1.5
= 15 Core
07 5B07
PHM
Pharmaceutical Management-I 3 3
10 X 3 =
30 -- -- -- Common
Total 19 19 190 14 7 70
Total credit 19+7 =26 and Total weighted credit point 190+70 = 260
GANPAT UNIVERSITY B. Pharm Semester-V Program
Teaching and Examination scheme
S.
N
Course
Code
Course Title
Teaching
Scheme
Hrs/Week
Total
Hours
Examination
Th. Pra. Th. Pra. Theory Practical Total
Int Ext Int Ext
1 5A01
HCP
Hospital & Community
Pharmacy
2 - 30 - 30 70 - - 100
2 5A02
PMB
Pharmaceutical
Microbiology
3 2 45 30 30 70 30 70 200
3 5A03
PCB
Pharmaceutical
Chemistry-V
(Biochemistry-I)
2 3 30 45 30 70 30 70 200
4 5A04
PCM
Pharmaceutical
Chemistry-VI
(Medicinal Chemistry-I)
3 3 45 45 30 70 30 70 200
5 5A05
PCG
Pharmacognosy-IV
3 3 45 45 30 70 30 70 200
6 5A06
PCL
Pharmacology- II 3 3 45 45 30 70 30 70 200
7 5B07
PHM
Pharmaceutical
Management-I
3 - 45 - 30 70 - - 100
Total 19 14 285 210 210 490 150 350 1200
GANPAT UNIVERSITY
B. Pharm. Semester- V
5A01HCP Hospital & Community Pharmacy
Theory (2 Hours / Week; 30 Hrs) Credit: 2
1. Organization and Structure of Hospital and Hospital Pharmacy
a. Responsibilities of Hospital Pharmacist, Including Community Service,
b. Supportive Service, Medical Tourism and Development.
c. Pharmacy and Therapeutic Committee.
d. Establishment, Budget Preparation and Implementation.
5
2. Hospital Formulary
Format, Content, Preparation and Keeping it updated.
3
3. Drug Information Service
a. Sources, Procurement, Retrieval and Computerization of Information, Poison
Information and Services.
b. Online Services on Disease, Treatment, Dosage, Administration, Concomitant
Prescription and Medication error.
3
4. Pharmacy Management Service
Purchase, Procurement, Storage and Organization, Inactive Control
Prescription Filling, Pricing, Insurance
3
5. Records And Reports
a. Patient Historical and Medication Profile.
b. Adverse Reactions
c. Patient Treatment Records and Auxiliary Reporting.
3
6. Manufacturing of sterile and non sterile products for captive consumption and
its extensional aspects to radiopharmaceuticals and manufacturing practices 5
7. Drug dispensing and distribution service for all the sectors of hospitals 3
8. Role of pharmacist in pre-packaging services of the hospitals, CSSD services 2
9. Accreditation aspects of hospital services and the rule pertaining to it 1
10. Role of contribution of pharmacist in community towards health care,
education, health and hygiene of society in general and patient counseling
services
2
References Books:
1. Hospital Organization and Management by Kurt Dan and Jonathan S. Ratich, 4th
Edition, CBS Publishers.
2. Remington: The science and practice of Pharmacy Remington by Reminston, 21th ed.,
Lippincott W. W. Philadelphia, 2009.
3. Hospital Pharmacy: Dr. R. K. Goyal and Parikh, B. S. Shah Publication.
4. Hospital Pharmacy by Hassan, Henry, 5th ed., Lea & Febiger,Philadelphia, 1986
5. Hospital organization and management by Kurt Dan and Jonathan S. Ratich, 4th
edition, CBS Publisher.
6. Merchant & Goyal’s A Texbook of Hospital Pharmacy: Dr. R. K. Goyal and Parikh, 11th
ed., B. S. Shah prakashan, Ahmedabad, 2011.
GANPAT UNIVERSITY
B. Pharm. Semester- V
5A02PMB Pharmaceutical Microbiology
Theory(3 Hours / Week; 45 Hrs) Credit:3
1. Introduction to Scope of Microbiology 2
2. General microbiology a. Structure and Bacterial Cell, Classification and taxonomy of Actinomycetes,
Bacteria, Spirochetes,Rickettsia and Viruses
b. Identification: Electron microscopy and Staining Technique
c. Nutrition, Cultivation and Isolation of Microbes
14
3. Control of microbes
a. Disinfection: Factor affecting Disinfection
i. Dynamics of Disinfection
ii. Evaluation of Disinfection
b. Sterilization: Methods of Sterilization, Validation of Sterilization Methods and
Equipment.
15
4. Analytical microbiology
a. Bacterial Counts
b. Sterility of Pharmaceuticals
c. Microbiological Assay of Vitamins and Antibiotics and Amino acids
14
Pharmaceutical Microbiology- I, Practical (2hr\week) Credit:1
1. Preparation of Various Media
2. Subculturing techmiques of Common Bacteria (Aerobic and Anaerobic)
3. Staining of microorganism
4. Methods of isolation of microorganism
5. Study of sterilization and their validation
6. Sterility testing of Pharmaceuticals as per IP
7. Study of bacterial counts
References Books:
1. Textbook of Microbiology by Tortora.
2. Pharmaceutical Microbiology, sixth edn, edited by W. B. Hugo and A. D. Rusell
Blackwell science.
3. Principles of Microbiology, Ronald M. Atlas. Second edn. W. C. Brown Publishers.
4. Bergeys manual of Systematic Bacteriology, Williams and Wilkins-A Waverly
company.
5. Disinfection, Sterilization and Preservation. Fourth edn, Symour S. Black. Lea and
Febiger Philadelphia, London.
6. Industrial Microbiology. Fourth edn, Prescott and Dunn. CBS Publishers and
Distributors.
GANPAT UNIVERSITY
B. Pharm. Semester- V
5A03PCB Pharmaceutical Chemistry – V (Biochemistry-I)
Theory (2 Hours / Week; 30 Hrs) Credit: 2
1. Biochemical organization of the cell and Transport processes across cell membrane 02
2. Bioenergetics: The Concept of free energy, Exergonic and Endergonic reactions,
determination of change in free energy from equilibrium constant, Sources and release of
energy, ATP and its biological significance, Other energy rich phosphate compounds
03
3. Introduction to Carbohydrates 05
4. Carbohydrate Metabolism
Conversion of Polysaccharides to Glucose-1-Phosphate. Glycolysis and fermentation and
their Regulation, Gluconeogenesis, Glycogenesis and Glycogenolysis, Metabolism of
Galactose and Fructose. Role of Sugar Nucleosides in Biosynthesis and Pentose-
Phosphate Pathway. Role of hormones in maintenance of blood sugar level
The Citric Acid Cycle Significance, Reaction and Energetic of the Cycle, Amphibolic Role of the cycle and
Glyoxalic Acid Cycle, Uric Acid Cycle
10
5. Co-enzymes: Vitamins as Co-Enzymes and their Significance. 05
6. Biological oxidation: Redox potential, Electron transport OR Respiratory chain with
enzymes and inhibitors, Oxidative Phosphorylation, mechanism of oxidative
phosphorylation, inhibitors of oxidative phosphorylation, Enzymes involved in
oxidation reduction reactions
05
Pharmaceutical Chemistry – V (Biochemistry) – Practical (3hr/week) Credit: 1.5
1. Separation of Amino Acids by Paper Chromatography and TLC.
2. Analysis of Normal and Abnormal Constituents of Urine.
3. Estimation of Chlorides, Phosphates, Acidity and Ammonia, Glucose in Urine.
4. Identification of Carbohydrates and Proteins.
5. Biochemistry of Cheese, Milk, Bread.
6. Identification of Substances of Physiological Importance in urine.
7. Estimation of Diastase in Urine.
8. Achromic and Chromic Period of Salivary Amylase.
References Books:
1. E. E. Conn and P. K. Stumpf, Outlines of biochemistry, John Wiley and Sons, New York.
2. A. L. Lehninger, Principles of biochemistry, CBS Publishers and Distributors, Latest edition.
3. Harper’s Biochemistry, Prentice hall International Inc. latest edition.
4. S. C. Rastogi, Biochemistry, Tata McGraw Hill New Delhi, Latest edition.
5. M.Cohn, K.S. Roth, Biochemistry and Disease. William and Wilkins co. Baltimore.
6. U.Satyanarayan, Biochemistry, Books and allied (P) ltd. Calcutta, Latest edition.
7. G. F. Zubay, W. W. Parson, D. E. Vance, Principles of Biochemistry, WCB Publishers, England.
8. S. Ramkrishnan, K. G. Prasannan, Textbook of medical Biochemistry, Orient Longman Madras.
9. S.K. Sawhney, Randir Singh,Introductory Practical Biochemistry, Narosa Publishers,New Delhi.
10. D. T. Plummer, An Introduction to Practical Biochemistry, Tata McGraw Hill New Delhi
11. J. Jayaraman, Laboratory manual in Biochemistry, Wiley eastern Ltd. New Delhi.
12. Textbook of Biochemistry by Dr. A. C. Deb, Latest edition.
13. Textbook of Biochemistry by Dr. Ramarao, Latest edition.
GANPAT UNIVERSITY
5A04 PCM Pharmaceutical Chemistry – VI (Medicinal Chemistry-I)
Theory: (3 Hours/week; 45 Hours) Credit: 3
1. An introduction to medicinal chemistry, History and development, Drug therapy 2
2. Physiochemical properties of drug molecules influencing biological activity
10 a. Solubility, Partition coefficient, Hydrogen bonding, Complexation, Ionisation, Redox
potential, Surface activity and protein binding
b. Stereochemical features of drugs: geometric and optical isomers, Bioisosterism
3. Heterocyclic compounds: Chemistry, preparation and properties of (a) Furan, thiophene, pyrrol and pyridine (b) Pyrrazole, imidazole, oxazole, isoxazole and thiazole (c) Pyrazine, pyridazine and pyrimidine, Quinoline, isoquinoline and indole
10
4. A study history, development, structure activity relationship, mechanism of action and synthesis* of following classes of drugs (*Synthesis of drugs mentioned in each category)
i. Drugs acting on respiratory tract: a. Antiasthmatics b. Expectorants c. Antitussive d. Respiratory stimulants e. Mucolytics f. Decongestants
6
ii. Drugs acting on gastrointestinal tract : a. Antacids b Antisecretary (Ranitidine) c. Proton
pump inhibitors (Omeprazole) d. Antiemetics e. Antidiarrheals f. Laxatives g. Prokinetics h.
Antispasmodics & drug modifying intestinal motility i. Drugs for irritable bowel syndrome j.
Local colorectal preparations k. Enzymes, carminatives & hepatobiliary agent
7
iii. Autocoids a. Histamines and antihistamines, Histamine receptors, H1antagonists, H2
antagonists (histamines, diphenhydramine, tripelenamine, chlorcylclizine, trimeprazine,
chlorpheniramine, promethazine, cyproheptadiene, antazoline, cetrizine). b. Eicosanoids: history
and discovery, eicosanoids biosynthesis, drug action mediated by eicosanoids, eicosanoids
approved for human clinical use.
8
iv. Diagnostic agents: Radiopharmaceuticals,Radiological contrast media, (diphenoxylate,
diatrizoic acid, sodium iothalamate)
2
Practical (3 hr/week; 45 Hours); Credit: 1.5
1. Organic spotting of solid-solid binary mixtures including eutectic mixture.
2. Synthesis of some organic compounds including some heterocyclic compounds.
3. Workshops on stereo models using some selected drugs
References Books:
1. Wilson and Giswolds Textbook of Organic Medicinal and Pharmaceutical Chemistry, J. Lippincott
Co. Philadelphia.
2. W. C. Foye, Principles of medicinal chemistry, Lea and febiger, Philadelphia.
3. H. E. Wolff, edn, Burgers Medicinal chemistry, John Wiley and sons, New York
4. Daniel Lednicer, Strategies for organic drug synthesis and design, John Wiley and Sons USA
5. B. N. Ladu, H. G. Mandel and E. L. Way. Fundamentals of drug metabolism and disposition.
William and Willkins co. Baltimore
6. I. L. Finar. Organic chemistry Vol. I and Vol. II. ELBS/Longman, London
7. Vogels Text books practical organic chemistry, ELBS/Longman, London
8. Mann and Saunders, Practical organic chemistry, Orient Longman, UK
9. Shriner, Hermann, Morill, Curtin and Fusion. The systematic identification of organic
compounds, John Wiley and Sons
GANPAT UNIVERSITY
B. Pharm. Semester- V
5A05PCG Pharmacognosy – IV
Theor y(3 Hours / Week; 45 Hrs)Credit: 3
1. Alkaloids: Sources, cultivation, collection, processing, commercial varieties, chemical constituents,
substitutes, adulterants, uses, diagnostic macroscopic & microscopic features & Specific
chemical tests of following Alkaloidal drugs:
Pyridine & Piperidine: Tobacco, Areca, Lobelia
Tropane: Datura, Belladonna, Hyocyamus, Dubosia, Cocca
Quinoline & Isoquinoline: Cinchona, Ipecac, Opium
Indole: Ergot, Rauwolfia, Catharanthus, Nuxvomica, Physostigma
Imidazole: Pilocarpus
Steroidal: Veratrum, Kurchi, Withania
Alkaloidal Amine: Ephedra, Colchicum
Purines: Coffee, Tea, Cola
Quinazoline: Vasaka
Diterpene Alkaloids: Aconite
32
2. Poisonous plants 2
3. Biosynthetic studies & basic metabolic pathways. Brief Introduction to biogenesis of
secondary metabolites of pharmaceutical importance. 8
4. Concept of stereoisomerism taking examples of Natural Products such as sennoside,
hyoscyamine, citral, menthol, quinine, ephedrine, papaverine, LSD etc. 3
Pharmacognosy – IV– Practical (3 hr/week) Credit: 1.5
1 Morphology of crude drugs containing Alkaloids mentioned in theory.
2 Histological Study of Alkaloidal drugs mentioned in theory.
References Books:
1 Wallis T.E., Text Book of Pharmacognosy, 5th Edition, Cbs Publishers and Distributors.
2 Qadry J.S., Shah and Qadry’s Pharmacognosy, B.S.Shah Publication.
3 Trease E and Evans W.C., Pharmacognosy, Balliere Tindall. Eastbourne, U.K.
4 Tyler V.C., Brady L.R. and Robers W.E., Pharmacognosy, Lea and Febiger, Ph.
5 Ashutosh Kar, Pharmacognosy and Pharmacobiotechnology, New Age International Publication.
6 Paul M. Dewick, Medicinal Natural Products: A biosynthetic Approach, Willy Publishers.
7 Kokate C.K, Purohit A.P. and Gokhale S.B. Pharmacognosy (Degree), Nirali Prakashan, Pune.
8 Kokate C.K. Practical Pharmacognosy, Vallabh Prakashan, Delhi.
9 Ansari, Pharmacognosy Textbook of Natural Products, Latest Edition.
10 Iyengar, Text Book of Pharmacognosy, Manipal Power Press.
11 Agrawal O.P., Natural Products, Vol I & II, Goel Publishing House, Meerut, 2004.
12 C.K. Atal and B.M. Kapoor, Cultivaiton and Utilization of Medicinal Plants, CSIR, New Delhi
GANPAT UNIVERSITY
B. Pharm. Semester- V
5A06PCL Pharmacology – II
Theory (3 Hours / Week; 45 Hrs) Credit: 3
1. Drugs acting on Nervous system:
a. Neuronal transmitters in CNS b. General Anesthetics c. Ethyl and Methyl Alcohols
d. Sedatives and Hypnotics, Anxiolytic Agents and Centrally acting Muscle Relaxants
e. Antipsychotics and Drugs used in Affective Disorders f. Antiepileptic Drugs
g. Antiparkinsonian Drugs h. Analgesics, Antipyretics and Anti-Inflammatory Drugs
i. Opioids Analgesics and Antagonists j. CNS Stimulants and Psychomimetic Agents
k. Drug Dependence and Drug abuse
22
2. Drugs acting on Cardiovascular and Renal System:
a. Cardiac Glycosides and other Cardiotonics b. Antihypertensive Drugs
c. Anti-anginal Drugs d. Anti-arrhythmic Drugs e. Antihyperlipidemic Drugs
f. Diuretics and anti-Diuretics
17
3. Drugs Acting on the Hemopoietic System:
a. Haematinics and Erythropoietin b. Drugs Affecting Coagulation, Bleeding and
Thrombosis c. Plasma Expanders
3
4. Gene Based Therapy 3
Pharmacology-II Practical (3 hr/week) Credit: 1.5
1. Experiments on Central Nervous System: Recording of Spontaneous Motor Activity, Stereotype,
Analgesia, Anticonvulsant Activity and Muscle Relaxant Activity
2. Study on Analgesic and Anti-Inflammatory Activity.
3. Simulation Experiments on Cardiovascular System,Effects of Drugs on Isolated Frog Heart.
4. Demonstration on the Effects of Various Drugs on the Rat blood Pressure.
5. To find out Nature of Unknown Drugs (Acetylcholine, Histamine, Bacl2, Physostigmine,
Atropine, Mepyramine And Papaverine) using Rat/Guinea Pig/Chicken Ileum Preparation.
6. Study on the Effects of CNS Stimulant (Coffee/Tea) on Human Volunteers.
References Books:
1. Rang H.P., Dale M.M., et al- Rang and Dale’s Pharmacology (2007) 6th
Edn. Churchill
livingstone Elsevier, USA.
2. Satoskar R.S., et al- Pharmacology and Pharmacotherapeutics (2005) 20th
Edn. Popular
Prakashan, Mumbai.
3. Harvel, R.A., Champe P.C. et al —Pharmacology (1997) 2nd Edn. Lippincott-Raven Company,
Philadelphia, New York.
4. Goodman and Gilman’s- The Pharmacological basis of Therapeutics, 11th
Edn., 2005, Mc Graw
Hill Companies, Pergamon Press, Singapore.
5. Seth S.D. Text Book of pharmacology,2nd
Edn., B.I. Churchill Livingstone Pvt. Ltd., New Delhi.
6. Goyal R.K, et al- Elements of Pharmacology, 19th
Edn., B.S. Shah Prakashan, Ahmedabad
7. Goyal R.K.-Practicals in Pharmacology (2010),9th
Edn., B. S. Shah Prakashan,Ahmedabad.
8. Kulkarni S.K.- Handbook of Experimental Pharmacology (2009), 3rd
Edn. Reprint, Vallabh
Prakashan, New Delhi.
9. Ghosh M.N,Fundamentals of Experimental Pharmacology, 4th
Edn., Hilton & Company, Kolkata
10. Tripathi K.D.- Essentials of Medical Pharmacology (2008), 6th
Edn, Jaypee Brothers Medical
Publishers (P) Ltd, Ahmedabad
11. Richard Finkel- Lippincott’s Pharmacology (2010), 4th
Edn., Wolter Kluwer Pvt. Ltd., Delhi
GANPAT UNIVERSITY
B. Pharm. Semester- V
Pharmaceutical Management -I
Theory (3 Hours / Week; 45 Hrs) Credit:3
1 Basic Principle of Management: Introduction to management, Evolution of
management theories, Basic managerial function(Planning, Organizing, Leading,
Controlling)
10
2 Managerial Economics & Foreign Trade: Nature And scope, Consumer behavior
and Demand analysis, Profit maximization of firms, Monopoly, Oligopoly, National
Income, Inflation, Foreign Trade & Rate function, EXIM policy.
8
3 Organizational behavior: Concept, Nature, Characteristics, Determinants and
importance, Concept of Perception, Motivation, Group dynamic, Leadership,
Organizational conflict.
8
4 Managerial communication: Definition, Objective of communication, Forms of
communication (Written; no-verbal, oral),Business Negotiation. 5
5 Business environment: Significance and nature, Relationship with Government,
Consumer Protection Act, Public and Private sector, Technological collaboration,
Liberalization, Globalization.
7
6 Total Quality Management: Juran’s and Deming’s principles, Small group activities,
Quality circles, Suggestion scheme, Project team approach, Continuous improvement. 7
References Books:
1 Principles and practice of management by L. M. Prasad
2 Organization theory by Stephens P. Robins, 3th
edition
3 Organization behavior by Stephens P. Robins, Pearson education
4 Organization behavior by Himalaya Publishing Pvt. Ltd.
5 Contemporary Business Communication by Scot O., 2004
6 Business environment by excel books and Himalaya Publishing
7 The 5 Pillars of TQM: How to Make Total Quality Management Work for You by Bill
Creech.
GANPAT UNIVERSITY
B. Pharm Semester-VI Program
Structure for B.Pharm Semester-VI Program
Sr.
No.
Cours
e
Code
Course Title
Teaching Scheme Hrs/ week Type of
Course
The
ory
Cred
it
Weighted
Credit Point Practical Credit
Weighte
d Credit
Point
01 6A01
DPH
Dispensing Pharmacy-II 2 2
10 X2 =
20 3 1.5
10X 1.5
= 15 Core
02 6A02
PBT
Pharmaceutical Biotechnology
3 3 10 X 3 =
30 3 1.5
10X 1.5
= 15 Core
03 6A03
PCB
Pharmaceutical Chemistry-VII
(Biochemistry-II) 3 3
10 X 3 =
30 2 1.0
10 X1.0
= 10 Core
04 6A04
PCM
Pharmaceutical Chemistry-VIII
(Medicinal Chemistry-II) 3 3
10 X 3 =
30 3 1.5
10X 1.5
= 15 Core
05 6A05
PCG
Pharmacognosy-V
2 2
10 X 2 =
20 3 1.5
10X 1.5
= 15 Core
06 6A06
CLP
Clinical Pharmacy-I 3 3
10 X 3 =
30 -- -- -- Core
07 6B07
PHM
Pharmaceutical Management-II 3 3
10 X 3 =
30 -- -- -- Common
Total 19 19 190 14 7 70
Total credit 19+7 =26 and Total weighted credit point 190+70 = 260
GANPAT UNIVERSITY B. Pharm Semester-VI Program
Teaching and Examination scheme
S.
N
Course
Code
Course Title
Teaching Scheme
Hrs/Week
Total Hours Examination
Th. Pra. Th. Pra. Theory Practical Total
Int Ext Int Ext
1 6A01
DPH
Dispensing
Pharmacy-II
2 3 30 45 30 70 30 70 200
2 6A02
PBT
Pharmaceutical Biotechnology
3 3 45 45 30 70 30 70 200
3 6A03
PCB
Pharmaceutical
Chemistry-VII
(Biochemistry-
II)
3 2 45 30 30 70 30 70 200
4 6A04
PCM
Pharmaceutical
Chemistry-VIII
(Medicinal
Chemistry-II)
3 3 45 45 30 70 30 70 200
5 6A05
PCG
Pharmacognosy
-V
2 3 30 45 30 70 30 70 200
6 6A06
CLP
Clinical
Pharmacy-I
3 - 45 - 30 70 - - 100
7 6B07
PHM
Pharmaceutical
Management-II
3 - 45 - 30 70 - - 100
Total 19 14 285 210 210 490 150 350 1200
GANPAT UNIVERSITY
B. Pharm. Semester- VI
6A01DPH Dispensing Pharmacy-II
Theory (2 Hours / Week; 30 Hrs) Credit: 2
1. Dispensing of proprietary medicine 02
2. Principles involved and procedures adopted in dispensing of:
Suppositories, passaries, enema and External preparations like cream, ointment, paste,
poultice, jellies, lotion, liniment, powders, etc; Solutions like douches, mouthwashes,
gargles, throat spray, throat paint etc.
12
3. Principles involved & procedures adopted in dispensing of Ophthalmic dosage forms 04
4. Incompatibilities
Physical and chemical incompatibilities, inorganic incompatibilities including
incompatibilities of metals and their salts, nonmetals, acids, alkalis, organic
incompatibilities. Purin base, alkaloids, pyrazolone derivatives, amino acids,
quaternary ammonium compounds, carbohydrates, glycosides, anesthetics, dyes,
surface active agents, correction of incompatibilities, therapeutics incompatibilities.
06
5. Dispensing of radiopharmaceuticals and its application in medicine 04
6. Future trends in dispensing 02
Practical (3hr\week; 45 Hours) Credit:1.5
1. All the possible practical regarding the topics covered in the theory including following S/S
formulations: Ointment, Cream, Paste Eye and Ear drops, Powders for external use
2. Moulded formulations: Suppositories and Pessaries
References Books:
1. Dispensing Pharmaceutical for students by Cooper and Gunn, 12th ed. CBS
Publishers & Distributers, New Delhi, 2000.
2. Pharmaceutical Dispensing by Sharma & Jain.
3. Dispensing Pharmacy by Hausa
4. Remington: The science and practice of Pharmacy Remington by Reminston, 21th
ed. Lippincott W. W.,Philadelphia, 2009 5. Pharmaceutical Practice by Diana M. Collett and Michale E. Aulton, ELBS Publishers
6. Pharmaceutical Practice, Edited by A.J. Winfield and R.M.E. Richards, 3rd ed.,
Edinburgh : Churchill Livingstone, 2004
7. Ansel’s Pharmaceutical Dosage forms and Drug delivery systems by Allen, Loyd V.,
9th ed., Walter Kluwer (India) Pvt. Ltd., New Delhi., 2009.
8. Pharmaceutical Calculations by Ansel ,Howard C.,13th ed., Walter Kluwer (India)
Pvt. Ltd., New Delhi., 2009.
GANPAT UNIVERSITY
B. Pharm. Semester- VI
6A02 PBT Pharmaceutical Biotechnology
Theory (3 Hours / Week; 45 Hrs) Credit:3
1. Introduction to biotechnology 2
2. Microbial genetics and variation 6
3. Genetic recombination:
transformation conjugation
a. Protoplast fusion, gene cloning and their applications, monoclonal antibodies
b. Study of drug produced by biotechnology, viz. activase, humulin, Hb etc.
8
4. Immunology and Immunological Preparation:
a. Immunity, primary and secondary defense mechanism, interferon
b. Principles of immunology, antigen antibody reactions and application, preparations of
vaccines, toxoids. Standardization and storage
12
5. Fermentation Techniques:
a. Screening of organism, preparation and preservation of master culture, design of fermentor,
various parameters and media used for fermentation
b. Recovery of fermentation products Flowsheets penicillin, streptomycin, Vit. B2, Vit. B12
12
6. Immobilization of Enzymes:
a. Techniques of immoblilization b. Factors affecting enzyme kinetics c. Applications 5
Practical: (3hrs\week; 45 Hours) Credit:3
1. Microbiological assay of antibiotics
2. Preparation and standardization of vaccines
3. Preparation of mutant , a. Gradient plate method b. Velvet replicate method
4. Design of fermentor
5. Study of shake flask technique
6. Production of alcohol using Bakers yeast
7. Extraction of citric acid from fermented mass
References Books:
1. Textbook of microbiology by Tortora G.J., 8th ed., Pearson education, New Delhi, 2004
2. Pharmaceutical microbiology by Denyer Stephen, 7th ed., Blackwell science, New Delhi, 2008.
3. Principles of microbiology, Ronald M. Atlas. 2nd ed., W. C. Brown publishers, 1996
4. Bergeys manual of systematic bacteriology Vol. 1-4, Krieg, N.R. 1st ed., Williams and Wilkins, 1984
5. Disinfection, sterilization and preservation. By Block Symour, 5th ed., Philadelphia,Lippincott,
London, 2001
6. Industrial microbiology by Prescott and Dunn. 4th ed. CBS Publishers & Distrubuters,
NewDelhi,1987.
7. Principles of fermentation tehchnology. by P. F. Stanbury, A. Whiteshaker, 2nd ed. Aditya
Books Pvt Ltd., New Delhi, 1997.
8. Microbiology, by Pelczar, Michael J. 5th ed., Tata McGraw Hill, New Delhi, 2002.
9. Industrial microbiology by Casida, L.E. 8th ed., New age international publishers, New Delhi,1996.
10. Fundamental principles of bacteriology by Sale, A. J., 17th ed., Tata McGraw Hill publishing
company Ltd., New Delhi, 2000.
11. Fundamentals of microbiology by Martin Forbischer, 6th ed. W.B. Saunders, 1957
12. Remington: The science and practice of Pharmacy Remington by Reminston, 21th ed., Lippincott
W.W.,Philadelphia, 2009.
GANPAT UNIVERSITY
B. Pharm. Semester- VI
6A03PCB Pharmaceutical Chemistry-VII (Biochemistry-II)
Theory (3 Hours / Week; 45 Hrs)
1. Introduction to Lipid 5
2. Lipid Metabolism: Oxidation of fatty acids, beta-oxidation and energetic, alpha-
oxidation, omega-oxidations,biosynthesis of ketone bodies and their utilization, biosynthesis
of fatty acids, control of lipid metabolism and metabolism of cholesterol.
6
3. Introduction to Proteins/Amino acids
Definitions, classifications, biological importance, color reactions, structure of protein,
protein denaturation, properties of amino acids, separation and identification of amino acids
methods for determination of N and C terminal amino acids, methods for determination of
primary structure of protein/peptide, essential amino acids and peptides
6
4. Protein/Amino acid metabolism
General concept of amino acid metabolism, amino acid pool, Transamination, Deamination,
biosynthesis of amino acids, catabolism of amino acids with diseases involves, conversion of
amino acids to specialized products or products with biological importance with diseases,
urea cycle, metabolic disorders of urea cycle
8
5. Enzymes 5
6. Nucleic acid and Biosynthesis of nucleic acids: Biological importance, types, brief
introduction of genetic organization of the mammalian genome, alteration and
rearrangement of genetic material, biosynthesis of DNA and its replication, DNA repair
mechanism, biosynthesisof RNA, protein synthesis
7
7. Genetic code, mutation and gene expression 4
8. Techniques used in biochemistry: Colorimetry, spectrophotometry, centrifugation,
electrophoresis and chromatography
2
9. Brief introduction to water and mineral metabolism 2
Practical: (3hrs/week; 45 Hours) Credit:1.5
Practicals based on analysis of lipids, calcium in serum, colorimetric analysis of glucose,
creatinine and urea in blood, titration curve of amino acid, determination of glucose, protein,
bilirubin and cholesterol in plasma, estimation of GOD-POD, SGPT, SGOT, qualitative and
quantitative estimation of aminoacids etc.
Reference books: 1. Outlines of biochemistry by Conn, E. E., 5th ed., John Wiley and Sons, New York., 2001.
2 Principles of biochemistry by Lehninger, A., CBS Publishers & Distributers, New Delhi, 1993
3 Harpers biochemistry by Murray, R. K., 25th ed., Mcgraw hill, New Delhi, 2002.
4 M.Cohn, K. S. Roth, Biochemistry and disease. William and Wilkins co. Baltimore, 1996
5 Biochemistry by Satyanarayan,U., 3rd ed., Books and allied (P) ltd. Calcutta, 2008
6 G. Zubay, W. W. Parson, D. E. Vance, Principles of Biochemistry, WCB publishers, England
7 Introductory Practical biochemistry by Sawhney, S. K., 1st ed., Narosa Pub., New Delhi, 2008.
8 D. T. Plummer, An introduction to practical biochemistry, Tata McGraw Hill New Delhi
9 J. Jayaraman, Laboratory manual in biochemistry, 1st ed., New Age International.
10 Practical Biochemistry, by G. T. Mills, G. Leaf, John Smith and Son Ltd.
11 Textbook of Biochemistry by Dr. Ramarao, Latest edition.
12 Textbook of Biochemistry by Dr. A. C. Deb, Latest edition.
GANPAT UNIVERSITY
B. Pharm. Semester- VI
6A04PCM Pharmaceutical Chemistry-VIII (Medicinal Chemistry-II)
Theory (3 Hours / Week; 45 Hrs) Credit: 3
1 Receptors and Drug action: Types of receptors, Theory of receptors, Drug-receptor
interaction and factors affecting the drug-receptor interaction
3
2 Drug metabolism: Introduction, importance of CYP450, general pathways of
Xenobiotics metabolism (functional group based classification of both phases with
examples), site of drug metabolism, factors affecting drug metabolism
4
3 Introduction, classification, nomenclature, mechanism of action, adverse effects,
therapeutic uses, structure activity relationship (SAR) and synthetic procedures of
selected drugs and recent developments of following categories to be covered.
4 Drug Acting on ANS Cholinergics: SAR- Acetylcholine mimetics- Muscarinic agonists
Anticholinergics: SAR:-Acetylcholine , antagonists- Muscarinic antagonists
Synthesis:- Neostigmine, Dcyclomine hydrochloride
Adrenergics:SAR: Phenylethanolamines,Synthesis: Adrenaline, Dopamine, Isoprenaline,
Ephedrine Adrenergic antagonists: Synthesis: Naphazoline,Salbutamol
Neuromuscular blocking agents and ganglionic blockers:
3
3
2
2
1
5 Drugs Acting on CNS: CNS stimulants: Analeptics, Antidepressants, hallucinogens
SAR:- Tricyclic antidepressants Synthesis:- amphetamine, Nikethamine, Fluoxetine,
Imipramine, Amitriptylline
CNS Depressants: General and local anesthetics, Sedative and hypnotics, Anxiolytics,
Antiepileptics, Antipsychotics, SAR:- Benzoic acid and Anniline derivatives with
Local anesthetic activity, Barbiturates, Benzodiazepines, Phenothiazines,
Butyrophenones, Synthesis:- Halothane, Lignocaine, Procaine, Benzocaine, Thiopental
sodium, Phenobarbitone, Chlordiazepoxide, Meprobamate, Phenytoin, Sodium valproic
acid, Ethosuximide, Carbamazepine, Chlopromazine, Trifluperazine
4
12
6 Antiparkinson’s agents 1
Opiod Analgesics and Non-Opiod Analgesics; SAR: Morphine, Pethidine, Benzomorphan, Morphinan, Synthesis: Pethidine, Methadone
Non Steroidal Anti-Inflammatory Agents, Anti Gout and Dmards: Synthesis:-
Paracetamol, Aspirin, Diclofenac, Ibuprofen, Indomethacin, Allopurinol, Mefenamic
acid, Nimesulide, Naproxen
4
5
7 Cognition enhancers 1
Practical 3 hr/week, 45 Hours; Credit: 1.5
1. Separation and qualitative analysis of Organic binary mixtures containing water insoluble
components having acidic, phenolic, amphoteric, basic and neutral nature (Solid +
Solid, Solid + liquid, Liquid + liquid and Eutectic mixtures) with derivative preparations.
2. Synthesis of specified drugs: Aspirin, paracetamol, methyl salicylate, phenytoin
Reference books:
1. J. N. Delagado and W. A. R. Remers, edn, Wilson and Giswolds Textbook of
organic medicinal and pharmaceutical chemistry, J. Lippincott Co. Philadelphia
2. W. C. Foye, Principles of medicinal chemistry, Lea and Febiger, Philadelphia
3. H. E. Wolff, edn, Burgers Medicinal chemistry, John Wiley and sons, New York
Oxford University Press, Oxfords
4. Daniel Lednicer, Strategies for organic drug synthesis and design, John Wiley and Sons
USA
5. B. N. Ladu, H. G. Mandel and E. L. Way. Fundamentals of drug metabolism and
disposition.William and Willkins co. Baltimore
6. I. L. Finar. Organic chemistry Vol. I and Vol. II. ELBS/Longman, London
7. Vogel’s Text books practical organic chemistry, ELBS/Longman, London
8. Mann and Saunders, Practical organic chemistry, Orient Longman, UK
9. Shriner, Hermann, Morill, Curtin and Fusion. The systematic identification of
organic compounds, John Wiley and Sons
10. Hans Thacher Clarke, A Handbook of Organic Analysis Qualitative and Quantitative,
Fourth edition, Orient Longmans Ltd.
11. Arthur Vogel, Elementary Practical Organic Chemistry, Part-I and II, Second edition,
CBS Publisher.
GANPAT UNIVERSITY
B. Pharm. Semester- VI
6A05PCG Pharmacognosy–V
Theory (2 Hours / Week; 30 Hrs) Credit: 2
1 Traditional drugs: Common and vernacular names, Botanical sources, morphology,
chemical nature of chief constituents Pharmacology categories and common uses,
marketed formulations of following traditional drugs:
Stem: Galo
Root & Rhizome: Satavari, Chitrak, Majith, Vaj
Bark: Arjuna, Ashoka, Sirish, Kanchnar
Leaf: Karen, Adusa, Nagod, Gimnema, Tilophora, Talispatra, Neem.
Fruit: Amla, Baheda, Harde, Malkangni, Kalijiri, Vidangh, Ghokharu, Bhilama, Piper.
Seed : Chakramadu, Karanj
Flower: Dhatakipushpa, Palash,
Entire herb: Apamarg, Methi, Eclipta, Kantakari.
Underground Stem: Garlic
Unorganised: Shilajit, Gugal.
Wood: Biyo
25
2 Herbs as health food. 2
3 Natural allergens, photosensitizing agents & fungal toxins 3
Pharmacognosy – V– Practical (3 hr/week) Credit: 1.5
1. Morphological identification of Traditional drugs mentioned in theory.
2. Histological study of Traditional drugs.
References Books:
1 Mukherjee Pulok, Quality Control of Herbal Drugs: An Approach to Evaluation of
Botanicals.
2 Kalia A.N., Textbook of industrial Pharmacognosy, C.B.S. Publisher, New Delhi.
3 S.K. Jain, B.K. Sinha and R.C. Gupta, Notable Plants in Ethnomedicine of India, National
Botanical Research Institute, Lucknow, Deep Publications.
4 Kirtikar K.R., Basu B.D., Medicinal plants, Volume-III, 2edition (reprint), M/S Periodical
experts.
5 Anonymous, Wealth of India, CSIR.
6 M.G. Chauhan, Microscopy of Leaf Drugs, Jamnagar Ayurveda University.
7 M.G. Chauhan, Microscopy of Bark Drugs, Jamnagar Ayurveda University.
8 Anonymous, Quality Standards of Indian Medicinal Plants, ICMR.
9 Vaidya Bapalal, Some Controversial Drugs in Indian Medicine, Chaukhambha Orientalia,
Varanasi.
10 Review on Indian Medicinal Plants, A. K. Gupta, Neeraj Tandon, Indian Council of Medicinal
Research, New Delhi, 2004,
11 Indian Medicinal Plants A compendium of 500 species, Sangam books Vaidyaratnam P. S.
Varier’s.
12 K.M. Nadkarni, Indian Material Medica, Bombay Popular Prakashan, Reprinted 2005.
GANPAT UNIVERSITY
B. Pharm. Semester- VI
6A06 CLP Clinical Pharmacy-I
Theory (3 Hours / Week; 45 Hrs) Credit: 3
1. Introduction: Development and scope of clinical pharmacy, concept of health care team,
Role of clinical pharmacist as a member of health care team and important functions
02
2. Basic concepts of pharmacotherapy:
a. Recording of medication history, self medication, nonprescription drug usage, improving
patient compliance and providing patient counseling, Communication skills- Behavioral
and interpersonal, with patients and other professionals.
b. Drugs used in special population: children, elderly (pediatric and Geriatric
considerations) and pregnant women. c. Interpretation of clinical laboratory tests:
Hematological, pathological and biochemical investigations as markers of Major organ
damage and their effect on drug therapy decisions.
12
3. Pathophysiology, Risk Factors, Complications and Management of the Following
Diseases:
a. CNS: Epilepsy, Parkinsonism, Alzheimer, Schizophrenia, Affective disorders, Pain and
Migraine. b. Cardiovascular: Hypertension, Coronary heart disease, Thrombosis, Stroke,
Congestive heart failure, Cardiac arrhythmias and Dyslipidemia. c. Renal: Acute renal
failure, Chronic renal failure. d. Anemia e. Obesity f. Glaucoma
20
4. Clinical Toxicology:
Definition of Poison and General Principles of Treatment of Poisoning with particular
reference to Barbiturates, Opioids, Organophosphorus, Atropine and Heavy Metal.
02
5. Concept of essential drugs and Rational drug use. 02
6. Drug interactions :
Prescription monitoring, documentation and methods for minimizing clinically relevant
drug interactions
01
7. Therapeutic drug monitoring 02
8. Drug induced diseases, adverse drug reactions and Pharmacovigilance 02
9. Pharmacoeconomics 02
Reference Books:
1. Roger Walker and Clive Edwards, Clinical Pharmacy and Therapeutics (2008), 4th ed. reprint,
Churchill Livingstone, Edinburgh.
2. Russell J. Greene and Norman F. Harris, Pathology & Therapeutics for Pharmacists (1994), 1st edn.,
Chapman & Hall, London, Madras.
3. Eric T. Herfindal et al., Text Book of Therapeutics: Drug and Disease Management (2006). 8th edn.,
Williams and Wilkins, Philadelphia
4. Boon Nicholas A., Davidson’s Principle and Practice of Medicine (2006), 20th edn., Churchill
Livingstone, Edinburgh.
5. Brian S. Katcher et al., Applied Therapeutics: The Clinical Use of Drugs (2004), Applied
Therapeutics Inc.
6. George S., Melmon and Morrelli’s Clinical Pharmacology (2008), 4th edn., McGraw Hill Medical.
7. Dipiro, Joseph, Pharmacotherapy: A Pathophysiological Approach (2011), 8th edn., McGraw-Hill,
New Delhi
8. R.K. Goyal et al., Elementals of Clinical Pharmacy (2009-10), 5th Edn., B.S.Prakashan Ahmedabad.
GANPAT UNIVERSITY
B. Pharm. Semester- VI
6B07PHM Pharmaceutical Management-II
Theory (3 Hours / Week; 45 Hrs) Credit: 3
1 Financial Management: Concept, Scope and objective of finance, Concept of Gross
working capital and net working capital, Leverage analysis, Modigliani miller approach
for finance decision, Walter’s and Gordon’s model for dividend decision.
8
2 Marketing Management: Nature and scope of Marketing, Market segmentation,
Product life cycle, Pricing decision, Branding and Packaging, Sales promotion,
Channel of distribution, Market information systems.
8
3 Production & operation Management: Transformation process model, Supply chain
management, Purchase management, Technique of production control, Maintenance
policy.
7
4 Human resource Management: Nature and development of personnel management;
Purpose and process of Human resource planning; Purpose, method and issues in
training and development; Job evaluation; Job satisfaction; Nature and importance of
industrial relation and union-management relation.
8
5 Legal aspect of Pharmaceutical Business: Intellectual property rights, Definition and
function of competition act and cyber laws, Memorandum and articles of association,
Bailment.
7
6 Pharmaceutical multinational Management: Growth of international business, Role
of MNC’s in developing countries, Hechsher-Ohlin theory, Nature and importance of
International marketing, Prahalad and doz’s strategy model, Role of world bank and
WTO, Export promotion council.
7
References Books:
1 Management Accounting by Khan and Jain, 3
th edition 2000
2 Marketing management by Rajan saxena
3 Production & operation Management by Adam j revert E.R., 5th edition 2000
4 Operation Management by Mc gregor D
5 Human resource Management by Aswathappa ,3th edition 2003
6 Business law of management by Bulchandani
7 International Business by Daniels, 2004