Diare
Jan 06, 2016
-
Wika Admaja S. Farm., Apt
Page *
Pengertian DiarePenyebab DiareMekanisme Terjadinya DiareKomplikasi Diare-DEHIDRASIORSTerapi Farmakologi
Page *
When somebody was called that he/she get diarrhea???
Page *
Page *
Page *
Page *
Malnutrisi dan malabsorbsi(termasuk intoleran thd laktosa) Infeksi (bakteri, virus)KeracunanSanitasi rendahObat2anPenyakit
Page *
Kekurangan enzim laktaseMengubah disakaridamonosakaridaPenumpukan disakaridaDi lumen ususFermentasi Perub pH dan Keseimbangan osmotikHiperosmolar Cairan masuk ke lumen ususDIARE!!!
Page *
PenyebabBakteri Salmonella Shigella E. Coli Clostridium difficileVirus Rotavirus Norovirus
Page *
Page *
Page *
Berdasarkan mekanisme terjadinya :SEKRETORIK EKSUDATIFOSMOTIKPERUB MOTILITAS USUS HALUS
Page *
Diare Osmotik Meningkatnya osmolaritas luminal Malabsorbsi, ion divalen (antasida), karbohidrat yg sukar larut
Page *
Berdasarkan lama terjadinya :
Page *
Menjaga keseimbangan cairan dan elektrolit.Meringankan gejala.Mengobati/menghilangkan penyebab.Memanagemen penyakit sekunder yg menyebabkan diare.
Page *
NON FARMAKOLOGIMenjaga kebersihanBanyak minum airDiet Hindari makanan kasar Hindari produk olahan susu Hentikan obat penyebab diare Menyusuiteruskan ORS4F(Food, Feses, Fly, Finger)
Page *
FARMAKOLOGIOpioidAdsorbenLactobacillusAnti KolinergikEnzim laktase
Page *
OPIOID : bekerja pd reseptor ex : loperamidslowing intestinal transit and increasing contact timeby directly inhibiting fluid and electrolyte secretion and/or stimulating salt and water absorption. ANTIKOLINERGIK : bekerja pd reseptor muskarinik slowing the movement of fecal matter through the GI tract ex : atropin, n-hiosin butil bromida Decrease intestinal muscle tone and decrease peristalsis of GI tract
Page *
LAKTOBASILUS : Supplying missing bacteria to the GI tract Suppressing the growth of diarrhea-causing bacteria Ex : L. acidophillusADSORBEN : adsorbsi : nutrisi, toksin, obat dan serat2 yg tercerna. coating the walls of the GI tract. sifatnya : NON SPESIFIK ex : Kaolin-Pektin, Attapulgit, Bismuth subsalisilat
Page *
DEHIDRASILoss of fluids from the body Mild, Moderate, Severe Sign/Symptom???KEMATIAN
Page *
Dehydration Assessment Scale
Page *
Why diarrhea is more dangerous for children ? Dehydration Malnutrition total cairan tub > dewasa sistem pencernaan yg imatur keb. nutrisi >>> lemahnya sist. imun normal flora usus blm sempurna
Page *
If: Diarrhea + MalnutritionThe RISK of DEATH is 4 fold higher than that of well nourished children
Page *
= Oral Rehydration Solution = Larutan Rehidrasi OralTujuan : mengganti cairan tubuh yg hilangKomposisi ???Bisakah dibuat sendiri?ORALIT???
Page *
Page *
ALGORITMA
TERAPI
DIAREDIARE ???AKUTKRONIKTERAPI SIMTOMATIK:ORSadsorbent,opioid..DietADA DEMAM/GEJALA SISTEMIKTDK ADA DEMAM/GEJALA SISTEMIKTERAPI SIMTOMATIK-+CEK FESESANTIBIOTIKATERAPI SIMTOMATIK
Page *
KRONIKInfeksi GIIBDMalabsorbsiObatGx motilitasdllKULTUR FESESNO DIAGNOSISDIAGNOSISTERAPI SIMTOMATIK :ORSDietHentikan obat penyebab diareAdsorbent,opioidTERAPI U/ PENYEBAB SPESIFIKALGORITMA
TERAPI
DIARE
Page *
******************************
