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J Mol Evol (2001) 52:144–156 DOI: 10.1007/s002390010143 © Springer-Verlag New York Inc. 2001 A Survey of the Molecular Evolutionary Dynamics of Twenty-Five Multigene Families…

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Slide 1ENCODE: understanding our genome Ewan Birney The ENCODE Project Consortium Biosapiens Network of Excellence Slide 2 Slide 3 ENCODE experiments Slide 4 AreaAssayGroups…

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Re-Engineering Philosophy for Limited Beings PIECEWISE APPROXIMATIONS TO REALITY W I L L I A M C . W I M S AT T HARVARD UNIVERSITY PRESS Cambridge, Massachusetts, and London,…

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Slide 1 CS273a Lecture 14, Fall 08, Batzoglou CS273a Lecture 14, Fall 2008 Finding Conserved Elements (1) Binomial method  25-bp window in the human genome  Binomial…

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Slide 1 Evolution at the DNA level …ACGGTGCAGTTACCA… …AC----CAGTCCACCA… Mutation SEQUENCE EDITS REARRANGEMENTS Deletion Inversion Translocation Duplication Slide…

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Slide 1 CS273a Lecture 11, Aut 08, Batzoglou Multiple Sequence Alignment Slide 2 CS273a Lecture 11, Aut 08, Batzoglou CS273a Lecture 11, Fall 2008 Index-based local alignment…

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Slide 1 Building synteny maps Recommended local aligners BLASTZ  Most accurate, especially for genes  Chains local alignments WU-BLAST  Good tradeoff of efficiency/sensitivity…

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Slide 1 Short Primer on Comparative Genomics Today: Special guest lecture 12pm, Alway M108 Comparative genomics of animals and plants Adam Siepel Assistant Professor of Biological…

Documents Part VI and Chapter 20 Biology Sixth Edition Raven/Johnson (c) The McGraw-Hill Companies, Inc.

Part VI and Chapter 20 Biology Sixth Edition Raven/Johnson (c) The McGraw-Hill Companies, Inc. Practically every plant, insect, and vertebrate gene exhibits some level of…

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Diversity: alpha – beta – gamma Beta diversity is a concept that helps us to cope with the fact that not every species lives everywhere  = avg +   =  avg…