Slide 1 CS273a Lecture 14, Fall 08, Batzoglou CS273a Lecture 14, Fall 2008 Finding Conserved Elements (1) Binomial method  25-bp window in the human genome  Binomial…

Slide 1 CS273a Lecture 11, Aut 08, Batzoglou Multiple Sequence Alignment Slide 2 CS273a Lecture 11, Aut 08, Batzoglou CS273a Lecture 11, Fall 2008 Index-based local alignment…

Slide 1 CS273a Lecture 9, Aut08, Batzoglou CS273a Lecture 9, Fall 2008 Quality of assemblies—mouse N50 contig length Terminology: N50 contig length If we sort contigs from…

Slide 1 CS273a Lecture 10, Aut 08, Batzoglou Multiple Sequence Alignment Slide 2 CS273a Lecture 10, Aut 08, Batzoglou CS273a Lecture 10, Fall 2008 Evolution at the DNA level…

Slide 1 CS273a Lecture 10, Aut 08, Batzoglou CS273a Lecture 10, Fall 2008 Local Alignments Slide 2 CS273a Lecture 10, Aut 08, Batzoglou CS273a Lecture 10, Fall 2008 After…

Slide 1 CS273a Lecture 4, Autumn 08, Batzoglou Fragment Assembly (in whole-genome shotgun sequencing) CS273a Lecture 5 Slide 2 CS273a Lecture 4, Autumn 08, Batzoglou CS273a…

Slide 1 CS273a Lecture 9/10, Aut 10, Batzoglou Multiple Sequence Alignment Slide 2 CS273a Lecture 9/10, Aut 10, Batzoglou CS273a Lecture 10, Fall 2010 Evolution at the DNA…

Slide 1 $399 Personal Genome Service $2,500 Health Compass service $985 deCODEme (November 2007) (April 2008) $350,000 Whole-genome sequencing (November 2007) Genetic Information…