I NTERNATI ONAL UNI ON OF CRYSTALLOGRAPHY BOOK SERI ES I UCr BOOK SERI ES COMMI TTEE E. N. Baker, New Zealand J. Bernstein, Israel P. Coppens, USA G. R. Desiraju, India E.…

Slide 1Phasing Goal is to calculate phases using isomorphous and anomalous differences from PCMBS and GdCl 3 derivatives --MIRAS. How many phasing triangles will we have…

Slide 1 Covalent bonding Slide 2 Learning Objectives Candidates should be able to:  describe, including the use of ‘dot-and-cross’ diagrams, covalent bonding, as in…

Slide 1 Computing Protein Structures from Electron Density Maps: The Missing Loop Problem I. Lotan, H. van den Bedem, A. Beacon and J.C. Latombe Slide 2 Protein Structure:…

Slide 1 X-ray Crystallography Kalyan Das Slide 2 Electromagnetic Spectrum 10 -1 to 10 nm 400 to 700 nm 10 -4 to 10 -1 nm 10 to 400 nm 700 to 10 4 nm X-ray radiation was discovered…

1.6 Bonding Specification Students will be assessed on their ability to: Ionic bonding a. recall and interpret evidence for the existence of ions, limited to physical properties…

Slide 1 Ionic bonding –evidence for ionic bonding, electron density maps –trends in radii –Born Haber cycles explaining formulae, why AlO is incorrect –polarisation…

Slide 1 1 Slide 2 A project of David Lutje Hulsik and Tim Hulsen May 7th, 2001 2 Slide 3 What are GPCRs? Membrane-bound receptors A very large number of different domains…

Slide 1 The Protein Databank The .pdb file format, and other resources for structural information Topic 5 Chapter 10 & 11, Du and Bourne “Structural Bioinformatics”…

Single-crystal X-ray Crystallography The most common experimental means of obtaining a detailed picture of a large molecule like a protein. Allows the resolution of individual…