Slide 1 Expected accuracy sequence alignment Usman Roshan Slide 2 Optimal pairwise alignment Sum of pairs (SP) optimization: find the alignment of two sequences that maximizes…

Slide 1 Slide 2 Fa05CSE 182 CSE182-L5: Scoring matrices Dictionary Matching Slide 3 Fa05CSE 182 Scoring DNA DNA has structure. Slide 4 Fa05CSE 182 DNA scoring matrices So…

Expected accuracy sequence alignment Usman Roshan Optimal pairwise alignment Sum of pairs (SP) optimization: find the alignment of two sequences that maximizes the similarity…

CSE182-L4: Scoring matrices, Dictionary Matching Class Mailing List [email protected] To subscribe, send email to [email protected] You can subscribe from…

BNFO 602 Lecture 2 Usman Roshan Sequence Alignment Widely used in bioinformatics Proteins and genes are of different lengths due to error in sequencing and genetic variation…

CSE182-L5: Scoring matrices Dictionary Matching Scoring DNA DNA has structure. DNA scoring matrices So far, we considered a simple match/mismatch criterion. The nucleotides…

CSE182-L5: Scoring matrices Dictionary Matching Silly Quiz PAM 1 distance Two sequences are 1 PAM apart if they differ in 1 % of the residues. PAM1(a,b) = Pr[residue a substitutes…