Slide 1 CS273a Lecture 8, Win07, Batzoglou Evolution at the DNA level …ACGGTGCAGTTACCA… …AC----CAGTCCACCA… Mutation SEQUENCE EDITS REARRANGEMENTS Deletion Inversion…

Slide 1 DNA Sequencing Slide 2 CS262 Lecture 9, Win07, Batzoglou DNA sequencing How we obtain the sequence of nucleotides of a species …ACGTGACTGAGGACCGTG CGACTGAGACTGACTGGGT…

Slide 1 CS262 Lecture 11, Win06, Batzoglou Some new sequencing technologies Slide 2 CS262 Lecture 11, Win06, Batzoglou Molecular Inversion Probes Slide 3 CS262 Lecture 11,…

Slide 1 CS262 Lecture 9, Win07, Batzoglou Real-world protein aligners MUSCLE  High throughput  One of the best in accuracy ProbCons  High accuracy  Reasonable…

Slide 1 Biological Motif Discovery Concepts Motif Modeling and Motif Information EM and Gibbs Sampling Comparative Motif Prediction Applications Transcription Factor Binding…

Slide 1 The Science of Information: From Communication to DNA Sequencing TexPoint fonts used in EMF: AAAAAAAAAAAAAAAA David Tse U.C. Berkeley CUHK December 14, 2012 Research…

Slide 1 CS262 Lecture 9, Win07, Batzoglou Phylogeny Tree Reconstruction 1 4 3 2 5 1 4 2 3 5 Slide 2 CS262 Lecture 9, Win07, Batzoglou Phylogenetic Trees Nodes: species Edges:…