© 2017 Cognizant © 2017 Cognizant
AWS Meeting
January, 2017
© 2017 Cognizant 2
Agenda/Objective of today’s discussion
CHALLENGES IN LIFE SCIENCES INDUSTRY
MARKET TRENDS ACROSS INDUSTRY
CLOUD ADOPTION JOURNEY
COGNIZANT AWS READINESS & INVESTMENTS
APPLICATION IN LIFE SCIECNES AND CASE STUDIES
DISCUSSION
Slides 3 & 4
Slides 5
Slides 11 & 12
Slides 13 - 20
Slides 21 & 22
CLOUD SERVICES ACROSS PHARMA VALUE CHAIN Slides 6 - 10
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We are looking at rapid infrastructure commoditization across industry
Emerging Players &Global Competition
Increased People CostsAnd Shrinking Margins
Changing Regulations &Environmental Concerns
Need to Rapidly Reduce
Production Cycles
Supply-Chain under SevereDistress and Needs
Remodeling
Fluctuating Energy Costs
Traditional Path toPurchase Is Changing
Customers areDemanding Seamless
Experience
Customers are Embracing New Technologies Faster
Increased Need To Multiply Operational
Efficiencies
Need To Reach Global Markets
Competitors Are UsingBig Data For Advantage
Transforming Branch/Store Formats
Enabling WorkForceTo Stay Relevant
BFSI RETAIL & CG MANLOG HEALTHCARE LIFE SCIENCESTECHNOLOGYCOMMUNICATION IMET & H
© 2017 Cognizant
A cloud-based planning layer can enable the
sharing of S&OP data with key stakeholders: contract manufacturers, branded
and generic business units, distributors and retailers.
Cloud CRM
Trends in Life Sciences industry in adaption of ‘Cloud’
Enveloping Core ERP with Cloud
Improve effectiveness of the Sales force and customer complaint
handling through Cloud CRM
This approach is being embraced by leading
pharmaceuticals manufacturers to comply
with mandates around serialization, extend
compliance to partners and leverage efficiencies across the extended supply chain.
Data held in systems outside of ERP (CAPA, MES or LIMS, for example) can
be shared on the same cloud platform. This
enables effective monitoring of
manufacturing processes and can provide early
warnings of problems in internal and external
operations
Companies can use on demand analytics for more productive (R&D analysis of
genomic, proteomic and clinical data) drug discovery
and also in targeted marketing and sales effort
Cloud-based Master Data(MDM) for Tracking,
Tracing
Cloud-based collaboration systems
On-demand Big Data Analytics
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How is IT in life sciences is being challenged?
Regulatory requirements: Ensuring continued regulatory compliance for system related issues along with applicable foreign regulatory guidelines
Data explosion: The amount of data managed by life science companies almost doubles in 3 months.
Data protection:
Fragmented & Siloed data systems: Bespoke applications and Siloed business units, each with its own infrastructure
High cost of ownership: Heavy upfront(capital) investment in current IT systems Pressure to reduce budgets while meeting increasing needs from
the business for responsiveness and agility
Elasticity: Low utilization of IT systems which are heavily provisioned to manage high demand during promotions for broadcasting and studios
Partner with other Research Labs;
Target Identity and Validation; In-silo
research
Perform initial laboratory and
animal tests; Clinical data management
Process development, scale-
up, commercial production, Supply chain management
Submission & Publication
Management; Regulatory compliance
Conduct Clinical Trials
Brand Management; Collaborate with
Doctors and Pharmacies;
Market and sell finished product;
Digital engagements
Aggregate & Periodic Reporting;
Customer support & analytics.
Drug Discovery Drug Development Regulatory Manufacturing PharmacovigilanceMarketing & Sales
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Amazon’s Elastic Cloud Computing (EC2)
Many Bio-informatics tool for protein or biologic sequence analysis have been deployed on EC2. Amazon, along with
other vendors, maintains copies of many of the publicly-available data sets on genomic and sequence data and makes them available to their clients as part of their overall cloud
environment.
In silico or Virtual screening
Screening involves using an automated tool to test
thousands of compounds for a specific biological activity.
Virtual screening allow researchers to greatly increase
the pace of finding new potential compounds while reducing costs for lab work.
Protein Docking Simulations
AutoDock is a suite of automated docking tools. It is designed to predict how small molecules, such as substrates or drug candidates, bind to a
receptor of known 3D structure.
Data mining/Big-Data Analytics
Cloud Computing – a game changer in Drug Discovery
Big Data Analytics helps to assess the biological systems, improve accuracy of target binding patterns and to simulate the activity of multiple drugs simultaneously on many tissues like in a “virtual” human.
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Shared Investigator Platform
Cloud LIMS allows real time specimen tracking and enable
researchers to reserve specimens for a specified time interval. Seamless lab sample
handling from entry to disposal, improving efficiency
and reducing turnaround time.
LIMS Electronic Data Capture
Cloud based electronic data capture allows patients to use any electronic device to report their information directly into the system. It allows real time tracking of data, also reducing
clinical trial costs by maximizing data entry and
workflow efficiencies.
Clinical Data Warehouse
Accelerated Drug Development using Cloud
A clinical and scientific data warehouse is used to manage, aggregate, and analyze clinical trial data. It also includes an operational data warehouse (ODW) for trial performance
metrics and a custom-developed trial master file (TMF)
tool to keep a comprehensive record of all clinical trial
activities.
The Shared Investigator Platform facilitates interaction
with multiple clinical trial sponsors, and enable study planning, study start-up and
study conduct activities while reducing the administrative
burden on site staff.
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Regulatory Master Data & Registration Life Cycle
Management
Cloud based publishing services in combination with
BPS services
“Combining content management and publishing
capabilities in the cloud offers a credible and innovative
alternative to the architecture of the past 15 years,” said
Steve Gens, Managing Partner of Gens and Associates; a Life
Science benchmark and consultancy.
Submission
Publishing
Electronic Document
Management & Archiving
Cloud based electronic document management &
archiving solutions will implement a centralized
storage repository across all business entities for corporate and affiliate dossiers, affiliate
HA submissions correspondence, all HA
correspondence and archival requirements by replacing the existing DMS systems, as well
as other central or affiliate Document Management
systems in use. Solutions available e.g. from:
Aris Global, Assured PV, EMC D2, EXTEDO, Lorenz, Mission3, Qumas, Samarind, Veeva
Regulatory Intelligence Services
Regulatory Affairs Services in the cloud
Provide a Regulatory intelligence platform
by
gathering & analyzing publicly available regulatory information.
communicating the implications of that information,
monitoring the current regulatory environment
to
Define Regulatory Strategy
Provide guidance for individuals and projects
On hands support for individuals
Registration Tracking & IDMP
The European Medicines Agency has mandated that
organizations doing business in the EU will need to submit
product information according to the ISO-IDMP standards by
July 2016.
Cloud based master data management solutions and
services offer not only compliance to new emerging standards but also combine those data standards with
other (global & local) life Cycle management activities
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Cloud based MES
A cloud based global serialization platform creates
reusable serial number generation profiles, support global standard and country-specific formats, define serial
number creation rules, manage serialized inventory
operations and meet traceability compliance
requirements.
Serialization Quality Management System
Cloud based quality and compliance software is an end-
to-end solution that automates all quality
processes and can be accessed from any location. Quality
processes supported include audits, change control,
complaint handling, CAPA, and supplier quality management,
etc.
Supply Chain Management
Pharma Manufacturing using Cloud services
Cloud based SCM tool facilitates better co-ordination between pharma company and contract
manufacturers. It provides a holistic reporting dashboard
which can be utilized by SCM, the purchasing department,
finance, marketing and others. It also provides a harmonized
visualization across the enterprise for merged
organisations having different SCM tools.
Cloud based MES helps in coordinating all aspects of production from tracking
inventory to managing quality control and can manage
processes across multiple worldwide facilities. It
facilitates faster deployment, reduced capital investment, scalability and access from
digital devices.
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Adverse Event Reporting
It helps in proactively identifying the safety issues, continuously assessing their impact on benefit-risk profile
and effectively mitigating risks across the product's lifecycle. It allows seamless integration with any safety database and provides support for safety intelligence and Benefit risk
assessment.
Integrated Signal Detection and Benefit Risk Assessment
Safety Data Warehouse
Cloud based safety data hub solution for the safety
operations and periodic reporting. It has optimized data model, intuitive web
analytics interface and intelligent content generation
techniques, which helps organizations improve
operational efficiencies, measure compliance and reduce periodic reporting
workload
Supply Chain Management
Leveraging Cloud Technology in Pharmacovigilance
Cloud enabled Adverse Event staging platform helps to reduce the time and effort involved in processing AEs and ADRs from start to end. It helps in standardization of the intake, triage, case management, and submission process of Individual Case Safety Reports (ICSR) and allows capturing case information from any device.
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Sales and Operations Planning
A cloud based Sales and operations planning helps in collaborating with external
suppliers and vendors. It allows real time sales
monitoring and order tracking. It aids in identifying sales
opportunities with a comprehensive view of customers. It provides flexibility during M&A.
New Product Introduction
Integrated product portfolio management platform which
helps in planning new product launch globally. It helps
marketing managers to track the launch timeline, campaign planning and other marketing
spend. It also helps in comparison of actual product
market position, costs, P&L against expectations.
Patient centric services
Centralised location for all patient related information
including demographics, communications, clinical and non-clinical data, and even pertinent information from
EHR. It allows real-time interaction with patients and
family. Also facilitates monitoring cases and
prioritizing tasks based on immediate needs and level of
importance to offer personalized care.
Digital Marketing
Cloud services in Sales and Marketing
Connecting Social media, mobile applications, wireless access and evolving technologies and collaborative approaches to delivering healthcare. Integrated communication platform to deliver information on product and therapeutic area leading to
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Assessment & Plan
Migrate
Setup
Manage
Define cloud strategies and create cloud migration plan
How does cloud apply to our organization and what specific workloads can we move there?
Setup a secure cloud environmentbased on the workload requirements
How can we ensure that the cloud setup is right for us
Transition workload to Cloud environment
How can we ensure that we migrate workloads correctly and quickly to the cloud?
How do we run and operate cloud based ecosystems? Manage cloud based systems
including Service Delivery
What is a typical cloud adoption journey
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Cloud Integration Challenges - Example
STRUCTURED DATA SOURCES
Liquid Insight Manager
Documentum
ERP(SAP)
AUTOMATIKA
UNSTRUCTURED
DATA EXTRACTION
Unstructured DataReader
NLP Based Entity Extraction
Rule Based Entity Extraction
Document Classification With
ML Model
UNSTRUCTUREDDATA
SOURCES
SmPC
File Share
Share Point
Database
Publish
Publish in form of
JSON
Data Management UI (Search, View, Edit)
IDMP Hub
Global Unique ID Maintenance
IDMP Data Model
Substances Packages
Medicinal
productsPharmaceutical
ProductsMarketing Authorization
Clinical ParticularsMaterialized
View
EMA
FDA
Other
Dat
a C
on
sum
ing
Syst
ems
Oth
er S
yste
ms
SAP
Sub
mis
sio
n
AR
ISG
lob
al
DATA
COLLECTION AND
CLEANSING
Data Collection
Data Validation
Data Cleansing
RIMS
CTMS
HL7
File Extracts
Hosted On-Premise
File
Ext
ract
s
Audit Trail
Workflow
Cross Reference
Product Attributes
Hosted on AWS
Control Vocabulary Maintenance
De Duplication
Product Relationship
Business Rules
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Appendic – if needed
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Cognizant Cloud Steps - A comprehensive tool-based framework that accelerates cloud enabled transformations by 25%-40%
• Application Migration Solutions to AWS
• Engineering Optimization Solutions for AWS
• Business Innovation Solutions for AWS
• Assess & Plan
• Set Up
• Migrate
• Manage
• Cloud Assessment Engine
• Hybrid Cloud Governance Foundation
• Cloud App Migration Foundry
• Hybrid Cloud Management Platform
• Cloud @ Customer
• Cloud @ Partner (AWS)
• Cloud @ Cognizant
Cognizant Cloud Steps- simplifying your cloud journey
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• AWS’s Premier Consulting Partner• Cognizant in the top 1% of all AWS partners
globally• Cognizant internal applications run on AWS• Transformational work across industries and
geographies• Funded Center of Excellence for Cloud Services• Co- Executive sponsorship, dedicated technical and
support resources, innovation fund
Partnership
Accelerators / Toolkits
Offering
Solutions and Platforms
• Cloud Workshop & Cloud Advisory Board • AWS Suitability Assessment Transformation services End
to end offering to help enterprise IT transformation• AWS Cloud Architecture Definition
• Application Transformation & Migration• Cloud Environment Design & Provisioning
• Cloud Auditing and Optimization Service • Cloud Applications Management
• Cognizant Cloud Pattern Studio• Cognizant’ CloudStepsTM Migration framework• AWS Assessment Kit – Assessment framework for AWS
suitability • Selenium Test Automation Platform • Cognizant Cloud Audit Ready
• BigDecisions – Business Solutions Platform• Cognizant Cloud Steps: a comprehensive Cloud
transformation framework.• Cognizant Cloud360 – Enterprise-class cloud management
‘hyper platform’• Cognizant asset Serv – Digital Asset Management Solutions• Cognizant Cloud Set: Software engineering platform that
accelerates development & testing• Cognizant Video as a Service – Cloud enabled Video platform• Cognizant Social Prism- social sentiment analysis platform
Cognizant - AWS Strategic Relationship
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AWS Cognizant
Economies of scale and efficiencies. Only pay for what you use.40+ cost reductions Up to 71% on Infra Cost saving!
Technology platform with industry-recognized certifications and auditsSoX, PCI, PHI, HIPAA, FISMA , ITAR, ISO
Provision systems in minutes vs. days, weeks or monthsScale resources automaticallyVirtual unlimited compute, storage and network capacity
Reduce dependency on InfraFree internal Infra resourcesto focus on innovation
Focus on business goals and Improvements
Cognizant Cloud Steps Transformation FrameworkCognizant Assessment EngineAccelerators and libraries
Cognizant Cloud Pattern StudioCognizant Audit Equip Cognizant Trail DigestCloud PCI & PHI frameworkData masking , Data fabric
Cognizant Cloud 360 tool for provisioning, orchestration, , monitoring and reporting
Rich Domain expertise to support business demand and goals Library of Best practices and automation scripts
Client
Lower TCO
Secured and Standardized platform
Rapid Provisioning & High Availability
Time to Market Align with Business Growth
Cognizant and AWS : Joint Value Proposition
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HIPAA Fabric-Security Solution
Jump start solution to manage HIPAA
compliance requirements in cloud
infra
READY
Expedited cloud adoption Roadmap
with suitability assessment Engine for
Workloads
READY
TCO Calculator
Standardized TCO calculation suitable
across all applications
READY
PCI Compliance Fabric
Jump start solution to manage PCI(1,2,3)
compliance requirements in cloud
infra
READY
OCM framework for cloud adoption
OCM framework definition to support
enterprise plan ahead of time on new needs post cloud adoption
W I P
Cloud Suitability Framework
AWS - Cognizant Unique Initiative : Solution Accelerators Build
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CLOUD TRANSFORMATION STRATEGY
Build multi-stage cloud transformation/migration roadmap
and strategy
1. WORKLOAD ASSESSMENT*
2. TRANSFORMATION ROADMAP*
3. CLOUD GOVERNANCE MODEL
4. APPLICATION READINESS ASSESSMENT*
5. MIGRATION WAVES & EXECUTION PLAN*
* Assessment & planning work would be done for few limited
workloads
ARCHITECTURE
Build Reference Architecture
1. AWS NETWORK ARCHITECTURE*
2. AWS SECURITY ARCHITECTURE*
* Based on the workloads assessed in the previous steps
PILOTS
Launch key application workload migration pilots as evidence of enterprise value and viability
1. APPLICATIONS
2. DATABASES
CLOUD EVANGELIZATION & TRAININGS
Value analysis, trainings and business stakeholder
evangelization
1. AWS VALUE ANALYSIS*
2. AWS ESSENTIALS*
3. AWS ARCHITECTURE TRAINING*
4. AWS SYSOPS TRAINING*
* As determined by previous workloads
Transformation Program Work Streams
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Reusable Framework/accelerators availableCognizant experience
Corporate FunctionsManufacturing & Supply ChainSales & Marketing R&D
• SAP BW & Hana
• Cognos
• WordPress
• Sitecore
• Myday
• PriceRight
• QlikView
• Revitas
• SAP (G)
• Trackwise (G)
• Oracle (G)
• Maximo
• Rockwell (G)
• Lorenz Docubridge (G)
• LIMS (G)
• Wonderware (G)
• MDM Informatica
• Kronos
• Smart Source
• Hyperion
• PeopleSoft
• Safety (Argus) (G)
• LIMS (G)
• Empower (G)
• EDC (InForm/Oracle/Rave) (G)
• CTMS (G)
(G) GxP applications
Typical COTS applications landscape ( Life Sciences – Example )
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Periodic Reviews/ Mock-Audits
SLA/OLA/Metrics Reporting
VendorReassessment
Testing (Vulnerability,
Performance, Backup, BCP & DR)
Perform Cloud vendor Assessment on parameters such as quality, information
security, data privacy/ policies, procedures, standards, data
center levels and certifications
Qualify Cloud
Evaluate Information Security, Data Privacy, Compliance,
Technology Risks and arrive at Quality assurance approach
Risk Assessment &
Validation Plan
Validate to ensure that the entire system (hardware/ software) is
installed and operating correctly and meets user requirements
Ensure effective change control
Perform Validation
Verify risk-based acceptance test strategy and ensure successful
installation and operational qualification, BCP and DR testing
is conducted
Governance –
Quality Assurance
Data center/ infrastructure maintenance, Change
Management and User Access provisioning procedures
Establish Support
Procedures
Methodology
Governance
Technology
The Transformation SolutionSaaS PaaS
IaaS
Goal : Ensure regulatory, information security and data privacy compliance of cloud hosted applications in a regulated business environment through a risk based validation framework and streamlined SDLC. The desired business outcome will be a high quality, cost efficient inspection ready cloud hosted solution.
Validation Framework for Cloud Hosted Applications
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Provisioning & Orchestration
Monitoring &Auto-Remediation
Metering & Chargeback
Analytics and Advisory
Transformation Advisory, Strategy, Business Case, Architecture Planning, Transformation execution, Change Management, Program Management , ERSS Security and Compliance offerings
Transformation Services
Cloud governance Foundation, Application Migration Foundry, Cloud Management Fabric, SLAs, Monitoring & Billing, Integration with On-Premise resources
Managed Services
Framework
Cloud Steps Transformation Framework
ToolsAWS Global
Infrastructure
EC2Auto
Scaling
S3
EBS
Import/Export
Storage Gateway
DynamoDB RDS
ElastiCache
Route53
Elastic LoadBalancing
Direct ConnectVPC
IAM
CloudSearchSES
SNS
SQS
SWF
AMI
EMRKinesis
WorkSpaces
GlacierCloudFront
Elastic Beanstalk
CloudFormation
CloudWatch
Management Console
Deployment & Management
Computing & Networking
Application Services
Storage & Content Delivery
Cloud Transformation with Cognizant & AWS
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Applications ON Cloud
• Re-Host• Migrate• Build• Extend• Test
Applications on IaaS or PaaS, Hybrid, SaaS, BPaaS
Cloud Application Services
Approach TO Cloud
Cloud Strategy & Roadmap
Services
• Assess• Select• Plan
Applications, Cloud, Software
Management OF Clouds
Cloud Management Services
• Monitor• Manage• Automate
Applications, VMs, Storage
Cognizant’s AWS Transformation Services
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The applicability of Cloud
Data Centre Consolidation Reduce
TCO and improve agility for the large
R&D IT Infra
EHR, Sensors Data Archival &
Disaster Recovery with reduced TCO
through cloud containers
Account based Selling\PlanningCloud Platform to
enable account based selling
Sales & Patient Analytics
on-demand Big Data Analytics Platform on
cloud
Research Collaboration
Cloud Collaboration Platform for global
workforce and partners
HPC on Cloud
Genomics sequencing and other heavy
computing requirements on
cloud
Marketing and SalesCloud based SaaS
solutions for managing products M&S
Multi-channel Customer Engagement Services
integrate and manage new channels
on Cloud
Web Scale Apps
Cloud powered web applications ex: app for fast
and efficient drug trial analysis
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Executed/ In-Flight Cloud Engagements in LS
A multinational pharmaceutical and biologics companyCloud enabled agile
research environment
A Pharmaceutical contracting solutions
provider helped leverage a SaaS based
Purchasing portal(GPO) to widen its coverage of alliance partners-
manufacturers, buyers, alliances
A medical devices, pharmaceutical and CPG manufacturer-
Cloud Consulting services for Data
Centre Consolidation
A multinational pharmaceutical, and consumer healthcare company- migrating SharePoint to cloud
A Pharmaceutical Major
CRM application migration to Cloud
An American pharmaceuticals and health care products
company
Cloud based
Healthcare Internet of things( IoT) solution
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Thank You