Organic Chemistry (OC)By AAR
The Rules1.Organic Chemistry-class in 14 times
(including mid-test and final test)2.Your attendance the class is 80% minimum3.The Credits/scores are: A to E4.The students shall receive the
tasks/challances: - Individual & group1.Study using full spirit, enthusiastic, active
and happy.
Formula Hidup
Sukses = Talent x Usaha x Konsistensi
Why OC is important for Pharmacist?
• The drugs are chemical (generally are Organic) → Properties of Drugs
• Drug interactions: food, suplement, other drugs, the targets, etc.
• Formulations: conformity and campatibility
• Drugs design and Delivery System
Example: Paracetamol (PCT)
• Acetaminopen, Brand: Panadol, Paramex, Sanmol, etc.
• Activity: mild analgesic
• Curative: under 30 min after oral dose
• Adverse effect: Exp. hepatotoxic, stomach bleeding.
Example: Others PhACs
What are the topics ?
• Introduction for OC• Chemical Bonding and Molecule Structure• Aliphatic compounds: Alkana, Alkena,
Alkuna• Aromatic compounds: polybenzene,
polyphenols• Heterocyclic• Alcohols• Aldehydes and Ketones• Caboxylic acid• Ethers and Esthers• Halogenated Organic compounds• Spectroscopy Analysis
References/Suggested reading:
• Organic Chemistry, by rj Fessenden & js Fessenden, 6th Ed. (text book)
• Organic Chemistry,Stanley H. Pine, et.all. (text book)
• Other Ref./literatures (more update)• Internet
Short Story: Organic Chemistry
• The ancient periode using plant as medicinal.• On Early 1900: Dhalton theory and Lavoiser• On 1814 Berzelius : oxidation process• 1832 Wohler and Liebig: Isomer• 1857 finding 4 valences at Carbon• On 2000 Century: Organic synthetic teq. • ….....and NOW more than 10 Million compounds
exist.
Structure & Chemical Bonding
Its Need knowledge about:
• Atomic structure• Atomic orbital• Electron configuration• Ion/covalen bonding• Valence bond theory• Lewis structure
• Hybridization• Formal Charge• Molecular orbital
Theory
Structure & Chemical Bonding
Structure & Chemical Bonding
The Atoms
The Atoms
The Atoms (inter-action)
The Atoms
The Atom Carbon
The Atom Carbon
The Atoms (inter-action)
Chemical Bonding Possibility in OC
Formal Charge (0)
Formal Charge (+1)
Formal Charge (-1)
The Atoms (Bonding)
Representing Molecule
Thank You