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11. 22. 43. Ebola 54. 135. 176. Ebola 307. 338. 379. 41 43
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1 2557 Hes Company Limited ISBN 978-616-11-2134-1
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11 2557
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(Ebola) 23 .. 2557 (Guinea) Ebola 218 141 191 115 115 72 63 Ebola 26 16 16 Ebola 6 Conakry ( 58 24 ), Guekedou ( 127 91 ), Macenta ( 22 16 ),Kissidougou ( 6 5 ), Dabola ( 4 4 ) Djingaraye( 1 1 ) 22 2557 Medecins SansFrontieres (MSF) Control and Prevention, US.CDC) (Lib Ebola 3 Guinea Liberia
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1
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Ebola 2557 3
(Sierra Leone) 3 (Viral hemorrhagic fever, VHF) VHF 98 10 (Lassa virus) 88 Ebola Lassa virus ( 24 .. 2557) Guinea Liber Sierra Leone [1, 2]
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2
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Ebola
3.1 Ebola 1 [3]
European Centre for Disease Prevention and ( 7 ) 2 (secondary transmission) Ebola .. 2543
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1 Ebola
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) Ebola
3
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) )
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:
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3.4 Ebola 1: Ebola
Ebola
1 21
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3: Ebola
(IATA) 1 Ebola 3 :
Ebola ( 27 .. 2557 );
;
2 3 Ebola 3
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Ebola 2557 11
Ebola 1
3 1 [4]
1 Ebola
21 ( 2) [4]
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Ebola 255712
2 Ebola
21
:- +/- 1 - Index case- - Index case
EbolaMarburg
Lassa
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(Hemorrhagic fever) Ebola Marburg Ebola Marburg [5]
4.1
Ebola Ebola
21
Ebola
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)
21
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(Case definition for surveillanc4
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4.2 (Routine surveillance) (Suspected case)
Ebola ( 27 .. 2557 )
(Confirmed case) IgM (Polymerase chain reaction, PCR) (viral isolation)
1. 2. 3. / 4.
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Ebola 2557 15
4.3
4.3.1
(Suspected case)
Ebola Ebola
Ebola 3
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Ebola 255716
Ebola
Ebola
4.3.2 (Probable case)
( )
(Laboratory confirmed case) RNA viru reverse transcriptase-polymerase chain reaction (RT-P Ebola
(Non-case) RNA **
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4
4.3.2
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/
1
24
24
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1: Ebola
............/................./...............1. ........................................................................................................................... ......................................
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post-mortem skin biopsy.......................................................................... : [ ] [ ] [ ] [ ] [ ] ............................................ .................................................. ............................... ..............................................................................................................
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Ebola 255720
1
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Ebola 2557 21
3. 21 Ebola
[ ] ...................... [ ] ................. [ ] ............... .................................................................................................. ...................................................................................... ................................................................................................ ......................................................................................
Ebola [ ] .......................... [ ] ................. [ ] ......................... .................................................................................................. ................................................................................................ ........................................................................................
............................................... .................................................
Ebola [ ] .......................... [ ] ................. [ ] ......................... .................................................................................................. ................................................................................................ ........................................................................................ ...................................................................... ..............................................
( ( ) )[ ] .......................... [ ] ................. [ ] ......................... ..................................................................................................... ........................................................................................................... ......................................................................................
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5. ...................................................................................................................................................................................................................................................................................................................................................................................................
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5.2
2 1 21 38.5 2: Ebola [7] 3: Ebola [6] 2 21 42 ) 24
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Ebola 2557 23
2: Ebola
1 ....................................................................... .................................. ...................................... [ ] [ ] ......... // .....................
( ) ................................................................................................................ ( ) ........................................................................................................... ()........................................()...................................... ..........................................
2 [ ] 3[ ] 4[ ] 5[ ] 6
............................................................................................................ 3 [ ] [ ] [ ] [ ] [ ] [ ] [ ] .......................................1. [ ] [ ] [ ] PPE [ ] [ ] [ ] PPE [ ] [ ] [ ] [ ] 2. [ ] [ ] [ ] PPE [ ] [ ] [ ] PPE [ ] [ ] ........................ fit test [ ] [ ]
[ ] [ ] 3.
[ ] ................ [ ] [ ]
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Ebola 255724
4. [ ] .................................. [ ] [ ] 5. [ ] [ ] [ ] ............................................................................................................................................................................................................................................................................
...................................................................................................................................... ............................................................................................................ ........................................................ ................................................ 1- 5 = / 1 2 PPE = / 1 2 PPE 3-4-5 =
4 [ ] / / [ ] [ ] [ ] [ ] [ ] ........................................1. [ ] [ ] [ ]
( 5) 2. [ ] [ ] [ ] 3. [ ] [ ] [ ] 4. [ ] [ ] [ ] 5. [ ] [ ] [ ] 6. [ ] [ ] [ ] 7. [ ] [ ] [ ] 8. [ ] [ ] [ ] 9. [ ] [ ] [ ] 10. 8 9 [ ] [ ] [ ]
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Ebola 2557 25
PPE [ ] [ ] ........................ fit test [ ] [ ] [ ] [ ]
..................................................................................................................................................................................................................................................................
................................................................................................................................. ....................................................................................................... ...................................................... ............................................ 1 = / 2, 4, 5 7 8 = / 3 6 8, 9 10 = /
5 [ ] [ ] / [ ] / [ ] ........................ ................................................. ................................................. .......................................................... ................................................. [ ] [ ] [ ] [ ] [ ] [ ] [ ] [ ] / / [ ] 1. [ ] [ ] [ ] 2. ? [ ] [ ] [ ]
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Ebola 255726
.................................................................................................................................................................................................................................................................................................................................................................................................................. ............................................................................................................
...................................................... .................................................. = / 1 2 =
6 1.
[ ] [ ] [ ] 2. [ ] [ ] [ ] .................................................................................................................................................................................................................................................................................................................................................................................................................. ............................................................................................................ ...................................................... .................................................. = / 1 2 =
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Ebola 2557 27
7 1. [ ] [ ] [ ] 2. [ ] [ ] [ ] 3. [ ] [ ] [ ]
8 Check list: / /
1. [ ] [ ] [ ] 2. [ ] [ ] [ ] 3. [ ] [ ] [ ]
................................................................. .................................................... ......... : 21 - = ......... [ ] [ ] ...................................................................................................................................................................................................................................................................................................................................................................................... ................................................................................................ ....................................................
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Ebola 255728
3: Ebola
:...................................................................... ............................................................... / 21 1.
.............................................................................................. [ ] [ ] ...................................................................... ....................................................... ..................................................................................................................................2. 1 2 3 4 5 6 7-
- - - - - - - - /- - -
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Ebola 2557 29
1 2 3 4 5 6 7- - - -
- - - - - -
3.
..................................................................................................................................................................................................................................................................
.................................................................................................................................
.................................................................................................................................
................................................................................................ ....................................................
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Ebola 255730
6.1
Ebola Ebola Ebola Ebola (Zaire) (Gabon)
2-21
1-2: 39 C (bradycardia) 2 (diarrhea rouge)
3-6: (soft palate) (dehydration)
5-7: 15 ( (popular tomaculopapular) 24
8-16: ( ) (severe dehydratio 12 (coma)
Ebola6
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Ebola 2557 31
12 14-16 (orchitis) hepatitis) transverse myelitis uveitis [6]
6.2 Shigellosis
Ebola (Toxemia) /
(Typhoid)
(lymphadenopathy) (re
(Malaria)
, (Leptospirosis), fever), (Typhus) / mononucleosis
(early stages of infection)
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Ebola 255732
Lassa fever (Pharyngitis)
(Yellow fever) Flaviviridae
(seroinvestigation) [6]
: Ebola (person-to-person transmission) Ebola (Endemic areas)
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Ebola 2557 33
7.1
Ebola
ELISA IgG IgM antigen Ebola Ebola
US-CDC (WHO) Ebola P4 [6]
7.2 7.2.1
3 1. (acute phase) 7
2. (convalescent phase)
14 paired serum 7-20 acute blood clot (Vacutainer type)
7
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(Viral isolation) 4 C P4
3. /
7.2.2
Ebola code3.6.6.4 Dangerous Goods (IATA) [6]
( 5 6)
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Ebola 2557 35
5 Ebola
EBOLA
Sampletransport container EBOLA - / -
- /
-
EBOLA PCR ELISA for IgG Antibody
EBOLA US-CDC :
3
EBOLA
3
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6 Ebola US-CDC
EBOLA US-CDC : 3
1. BSL-3 () Deep freezer
US-CDC2. US-CDC3. IATA
US-CDC
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8.1
Ebola
[6]
8.2
8
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stethosco
()
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Ebola 2557 39
1)
(Bleach) 1:10 1:100 10
2)
3) sterilization
autoclave stream sterilizer 20
/ negative pressure
7 21
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60 C 1
21
8.3
[6]
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Ebola 2557 41
9.1
- Ebola - - -
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-
-
- -
9.2 /
- -
9
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- -
9.3
- - - - - - -
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3 Emerging and Other Communicable Dis [6]
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Ebola 2557 43
Ebola
1. Ebola
Ebola ( ) .. 2519 Ebo - -
50
2. Ebola (lipid-enveloped)
(RNA) Filoviridae IgG ELISA (convalescent) P4 4 (Zaire) (Sudan) (Ivory Coast) (Gabon)
5 (Reston) (Macacafascicularis)
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Ebola 255744
(Accidental host)
3. 2-21 ( 5-12 )
(maculopapular rash)
50- 90
Ebola ( )
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Ebola 2557 45
Ebola ( Ebola ) Ebola
4. /
3-17
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Ebola Ebola Reston
5.
(supportive) hyper-immune sera [6]
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Ebola 2557 47
Ebola
.. 2504 - 2505 (Ethiopia) Ebola Ebola (Yellow fever)
.. 2515 (Zaire) E
.. 2519 - (Sudan) 284 150 ( 52) -
318 280 ( 88) Ebola
.. 2520
.. 2522 34 22 ( 64)
.. 2532 - 2533 Reston (Virginia) (USA) Ebola Reston (Macacafascicularis)
.. 2535 (Italy) Ebola Reston (Macacafascicularis)
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Ebola 255748
.. 2537 12 1
.. 2538
315 244 ( 77) .. 2539 - 37 21 ( 57) (Texas) USA Ebola Reston
2539 2540 61 45 ( 78) 1 (South Afri Ebola 1 [6]
.. 2540 - 2556 Ebola
.. 2557 24 - 25 Guinea Ebola 4 86 59 68.5 LiberiaSierra Leone Pasteur Institute Ebola Zaire
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Ebola 2557 49
Guinea CDC U Guin 20 Guinea Ebola 208 136 112 Ebola 25 18 24 16 24 21 Liberia
34 11 Ebola Zaire ( 97) Guinea Liberia 23 2557 Liberia The International Red C(IRC), Pentecostal Mission Unlimited (PMU)-Liberia Sa Pasteur CDC 7 Guinea 3 Liberia [1, 2]
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Ebola 255750
- Ebola
Ebola Ebola
Ebola
Ebola
2-21
9
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Ebola 2557 51
Eb
Ebola
Ebola Ebola Ebola
Ebola [8]
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Ebola
21
Ebola 1) Ebola
2)
(IATA)
1) Ebola
/ Ebola
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Ebola 2557 53
( )
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2)
Ebola
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Ebola 255754
Ebola (IATA)
Ebola
Environment Protection Agency (EPA) 1%
30
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Ebola 2557 55
(compressed air)
( )
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Ebola
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( )
(
) [9]
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Ebola 255756
1. World Health Organization, Regional Office for Africa. Ebola virus diseApril 2014).[] 25 2557. [ 5 2557.]http://www.afro.whoclusters-a-programmes/dpc/epidemic-a-pandemic-alert-and-response/odisease-west-africa-25-april-2014.html
2. Centers for Disease Control and Preventions.2014: Ebola HemorrhagicLiberia. [ ] 2 2557. [ 11 2557.] http://www.cdc.gov/vresources/outbreaks.html
3. European Centre for Disease Prevention and Control.Outbreak of Ebola v2014. Stockholm: ECDC; 2014.
4. European Centre for Disease Prevention and Control.Risk assessment guon aircraft. 2nd ed. Stockholm: ECDC; 2010.
5. World Health Organization and Centers for Disease Control and PreventiIntegrated Disease Surveillance and Response in the African Region, BraAtlanta, USA,: 1-398.
6. World Health Organization (1997). WHO recommended Guidelines fResponse: Ebola Haemorrhagic Fever (EHF).Geneva, Switzerland.: 1-307. Health Protection Surveillance Centre (2012).The Management of Vira
Dublin, Ireland: 1-1178. World Health Organization, Regional Office for Africa. Frequently A
disease.[ ]. [ 5 2557.]http://www.afro.who.int/en/clustersepidemic-a-pandemic-alert-and-response/epr-highlights/3648-frequently-afever.html
9. Centers for Disease Control and Preventions.Interim Guidance about EboCrews, Cargo and Cleaning Personnel, and Personnel Interacting with A].[ 5 2557.] http://www.cdc.gov/vhf/abroad/airline-worker
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:
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:
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