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FISIOLOGI PEMBULUH DARAH
PROGRAM STUDI ILMU KEPERAWATAN UNIVERSITAS ESA UNGGUL.
PERTEMUAN 4
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• Arteri: darah dari jantung
• Kuat & Elastis
• Mengalirkan darah ke kapiler
• Kapiler: pertukaran dengan sel
• Vena
• Membawa darah kembali ke jantung
• Katup
SISTEM PEMBULUH DARAH DAN KARDIOVASKULERSISTEM PEMBULUH DARAH DAN KARDIOVASKULER
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SISTEM PEMBULUH DARAH DAN KARDIOVASKULERSISTEM PEMBULUH DARAH DAN KARDIOVASKULER
Figure 15-1: Functional model of the cardiovascular system
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
Make Up of Bllod Vessels: Arteries and ArteriolesMake Up of Bllod Vessels: Arteries and Arterioles
Figure 15-2: Blood vessels
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
• Bypass capillaries
• Large cells
• Speed flow
MetarteriolesMetarterioles
Figure 15-3: Metarterioles
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
Blood Pressure: Berasal dari kontrasi ventrikelBlood Pressure: Berasal dari kontrasi ventrikel
Figure 15-4: Elastic recoil in the arteries
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
• Pulse pressure = Systolic–Diastolic
• Mean arterial pressure (MAP) = Diastolic + 1/3 pulse pressure
More Blood Pressures: Pulse and Mean Arterial PressuresMore Blood Pressures: Pulse and Mean Arterial Pressures
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
More Blood Pressures: Pulse and Mean Arterial PressuresMore Blood Pressures: Pulse and Mean Arterial Pressures
Figure 15-5: Pressure throughout the systemic circulation
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
Faktor-faktor yang mengatur MAP Faktor-faktor yang mengatur MAP
• Volume darah
• Cardiac output
• Resistansi
• Distribusi
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Faktor-faktor yang mengatur MAPFaktor-faktor yang mengatur MAP
Figure 15-10: Factors that influence mean arterial pressure
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Distribusi Darah pada Organ TubuhDistribusi Darah pada Organ Tubuh
Figure 15-13: Distribution of blood in the body at rest
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
Pertukaran Kapiler: Tekanan Osmotik Koloid yang KonstanPertukaran Kapiler: Tekanan Osmotik Koloid yang Konstan
• Protein tetap berada di kapiler
• Airr, oxygen, glukosa – keluar
• CO2, sampah nitrogen, air – masuk
• Aliran keluar dari bagian arteri, masuk pada venous
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Pertukaran Kapiler: Tekanan Osmotik Koloid yang KonstanPertukaran Kapiler: Tekanan Osmotik Koloid yang Konstan
Figure 15-18a: Fluid exchange at the capillary
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
• Net filtration – net absorption = net out flow
• About 2 L/day collected by lymph vessels
Net Out Flow Into ECFNet Out Flow Into ECF
Figure 15-18b: Fluid exchange at the capillary
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
Regulasi Tekanan DarahRegulasi Tekanan Darah
• Pusat Kontrol Jantung di Medula
• Refleks Baroreceptor
• Carotid
• Aortic
• Ginjal: volume darah
• Hypothalamus & Corteks: stress, “blushing”, dll.
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
Regulasi Tekanan DarahRegulasi Tekanan Darah
Figure 15-22: The baroreceptor reflex: the response to increased blood pressure
