ThermoScientific XSERIES 2 ICP-MS - Thermo Fisher ….pdf · Embrace all elements ThermoScientific XSERIES 2 ICP-MS Part of Thermo Fisher Scientific elemental analysis

Embrace all elements

Thermo ScientificXSERIES 2 ICP-MS

Part of Thermo Fisher Scientific

e l e m e n t a l a n a l y s i s

XSERIES 2 ICP-MSThe most comprehensivequadrupole ICP-MS platformfor high performance acrossthe entire periodic table.

XSERIES 2 ICP-MSXSERIES 2 ICP-MSXSERIES 2 ICP-MS

XSERIES 2 ICP-MS

The Thermo Scientifc XSERIES 2Quadrupole Inductively CoupledPlasma Mass Spectrometer(ICP-MS) provides reliableinterference removal in allsample types with a singlecollision gas and Kinetic EnergyDiscrimination. It is a powerfuland precise measurement tooldesigned to maximize productivityin the laboratory across a widerange of applications.

The XSERIES 2 ICP-MS offers analyticalscientists:

• A compact, bench top ICP-MS that iseasily incorporated into any laboratory

• The highest throughput with protocolcompliance

• Maintenance free lens system and massspectrometer for routine 24 / 7 analysesin clinical, environmental, geochemicaland industrial laboratories

• ‘Plug in’ design with the highest signal-to-noise of any Quadrupole ICP-MS

• Advanced H2/He collision cell technology,licensed from Battelle, provides uncom-promised multielement analysis for allelements including Ca, Fe, As and Se

• Application tailored interface designs forno-compromise analysis

• Low learning curve software for rapidacceptance in multi-user environments

• Seamless integration as a detector fortransient signals

• Unique bi-directional control with LC,GC and Laser Ablation.

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EmbracePerformance

PlasmaScreen™ Plus TechnologyGives sensitivity enhancement with boththe standard Xt and Xs interface optionswithout compromising the instrumentbackground. It is used with the Xt interfacefor improved hot plasma detectioncapability in both standard and CCTED

measurement modes or with the Xs forenhanced cool and hot plasma performancefor ultra trace analysis of high puritymatrices, giving sub-ppt detection of Li, Na,K, Ca & Fe.

LA-ICP-MS applications alsobenefit from the improved signal-to-background with PlasmaScreenPlus Technology

Xs InterfaceFor ultra-traceperformance in theanalysis of semi-conductor reagents or othertrace determinations such as theanalysis of radionuclides or REEs ingeological materials, high sensitivityinterfaces can be fitted quickly and easily.

Peltier CoolingA Peltier cooled, low-volume conical spraychamber fitted with a fixed impact beadand a high performance glass concentricnebulizer is provided to enhance stabilityand to enable fast washout and minimumcross contamination. The Peltier block iselectronically controlled enabling differentspray chamber temperatures to be usedwithin an analytical method.

CCTED

Third-generation collision cell technologyincorporating kinetic energy discriminationefficiently eliminates matrix and argon-based spectral interferences using simplereaction gases, minimizing unwanted sidereactions in the cell without complexelectronics.

Gas Control ModulesUp to 2 additional mass flow controllers canbe fitted to improve organic matrix handlingand/or enhance the use of high-performance,low-flow nebulizers.

* This product is protected undervarious patents, including one or more ofthe following:US4760253 US6259091 GB2285170JP1778906 US5051584 EP0231131CA2045484 JP2516840 US5514868EP0407539 CA2143669 JP2922647US5767512 EP0871977 CA2241320AU0705918

No Compromise Solution

Advanced instrument design brings high performance multi-element ICP-MS capabilitiesto all laboratories

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Operator-friendlyAll functions of the PlasmaLab suite aredesigned with a low learning curve toguarantee rapid familiarization andacceptance in routine analyticalenvironments. All key instrument operationsare made using easy to follow Wizards.Extensive software automation allows theoperator to reliably perform Autotunes andassess instrument performance through theuse of Performance Reports, guaranteeingconsistent performance in all analysis modes.

Different analysis modes (Xs-/Xs+, CCTgas and/or KED) are all software defined,allowing for rapid, automated in-scanswitching for optimum productivity. All userinput is defined using a spreadsheet styleinterface with full implementation of dropdown boxes and modern click and dragmouse controls for rapid data entry. Right-click menus allow access to commonly usedfunctions, for example when copying datasets to the Windows™ clipboard for directentry into any other application.

“Designed-in” application-specific protocolsTemplates can be tailored specifically toyour application needs to make it easy evenfor inexperienced operators to achievequick, accurate results.

Integral QA/QC packageAutomated real-time data validationroutines significantly reduce the number ofsample re-runs, improve productivity andlower overall cost per analysis.

Flexible reportingAnalytical reports can be adjusted to yourlaboratory requirements, using PlasmaLab’sflexible report generation and LIMSconnectivity.

Ease of Use and Performance Combined

The dedicated Thermo Scientific PlasmaLab software suite for the XSERIES 2 provides aseamless control over all aspects of ICP-MS analyses, instrument control and quantification,reflecting over 20 years of ICP-MS experience.

Simplicity through automation

Sample list showing QC flags

Simple spreadsheet style data entry

Flexible report generation anddata export

EmbracePracticality

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Maximum Uptime … Minimum Maintenance

World’s smallest benchtop ICP-MSThermo Fisher ScientifIc has designed theworld’s smallest benchtop ICP-MS withtoday’s busy laboratories in mind. Withcovers constructed from inert compositematerials, the XSERIES 2 ICP-MS is equallyat home in either high throughputenvironmental monitoring laboratories, busyclinical analysis laboratories or demandingsemiconductor clean room environments,where space is at a premium.

DetectorAn advanced simultaneous, discrete dynodeelectron multiplier, with nine orders oflinear dynamic range, accurately measuresmajor and minor concentrations in a singleanalytical run. Intelligent over-rangeprotection and fully-automated detectorcross-calibration for superior linearity, leadsto unparalleled long term signal and cross-calibration stability between detector modes.

A unique cradle design ensures nocable connections are required inside thehigh vacuum area for improved reliabilityand easy replacement.

Careful attention to detail ensures thatboth heat dissipation and extractionrequirements are minimized, reducingenvironmental contamination and initialstart-up costs.

Future-proof technologyIntelligent modular design and a range ofunique plug-and-play performance optionsprovide flexibility and a guaranteed upgradepath to maintain future regulatorycompliance.

Maintenance-free massspectrometerBased on innovative design models used inconsumer manufacturing processes, aradical engineering approach has producedan ICP-MS solution that’s as practical as itis powerful. The maintenance-free InfinityII

Lens, quadrupole and detector systemsensure maximum productivity betweenscheduled preventive maintenance visits.

Highest signal-to-noise ratio ofany ICP-MS with collision cellcapabilityA compact, top-entry, cable-free vacuumhousing incorporating the robust InfinityII

Lens and an off-axis high-performancequadrupole mass analyzer combine todeliver the highest signal-to-noise ratio ofany quadrupole based ICP-MS, rivaling thatof Sector Field ICP-MS.

Advanced technology doesn’t have to be complicated. The XSERIES 2 ICP-MS makes eventhe most sophisticated of analytical protocols easy to implement.

Optimization for maximum running time

EmbraceProductivity

Optimized Sample InterfaceThe Xt Interface is ideally suited to routineenvironmental, clinical and geochemicalapplications. The specifically designedgeometry of the Xt skimmer cone minimizespolyatomic species in complex matricesmaking possible, for example, the detectionof iron at �g/L level. The Xt interfaceprovides an application-optimized massresponse curve, with reduced sensitivity atlower masses – enabling the measurementof over 200 mg/L of Na, Ca and other matrixelements – while, in the same scan,delivering the detection power required forultra trace analytes, such as Cd, Pb and Hg.By using the XSERIES 2 switchablequadrupole resolution, this dynamic rangecan be further extended to over 400 mg/Lfor sodium.

Optimized, accessible sampleintroductionAn efficient, stable sample introductionsystem is the foundation to maximizingsample throughput. The XSERIES 2 featuresan integrated sample introduction systemwith the nebulizer and spray chambermounted externally to the torch box for easeof access and maintenance. The openarchitecture allows for trouble-freeconnection to any sampling accessory, suchas LC, GC and Laser Ablation.

Optimized plasma conditionsA one-piece quartz ICP torch mounts intoa ‘snap-in’ holder to prevent misalignmenton installation. The torch position isadjustable in x, y, z planes under computercontrol. Optimized settings can be storedand recalled in an analytical method alongwith other instrument parameters.

Productivity packsPredefined protocols facilitate worldwideregulatory compliance reducing start-uptime and increasing productivity. Methodtemplates, optimized acquisition parametersand customized reporting options areincluded to ensure the lowest cost persample analysis.

Unique productivity enhancement toolssuch as intelligent monitored uptake/rinseand protocol optimized autotune parameterssignificantly improve throughput andoperating efficiency.

Even the simplest configuration of theXSERIES 2 ICP-MS guarantees conformanceto latest worldwide environmentalregulatory protocols including US EPA 200.8,US EPA 6020A, US ILM05.3, Japanese JISK0102, German TVO, and UK DWI NS30.

The XSERIES 2 ICP-MS is also ideallysuited to the analysis of a wide varietysamples in other market areas, whichdemand high analytical performancecoupled with high sample throughput andmaximum uptime. The XSERIES 2 handlesclinical and pharmaceutical matrices withease, facilitating toxicology, nutritional andbiomedical studies. The high signal tonoise and efficient interference removalmake the XSERIES 2 the instrument ofchoice in fields such as geology andradionuclide measurement.

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Intelligent sampling for greater throughput

Additional functionality and convenience features, as well as new and improved sampleintroduction systems, add value and even greater productivity to your XSERIES 2 ICP-MS.

ESI SC-FAST autosamplerThe SC-FAST from ESI consists of anautosampler, a 6 port switching valve,on-line mixing of diluent/internal standardand a robust, low dead volume nebulizerand peltier cooled spray chamber. A sampleloop on the injection valve takes on the roleof the sample vial. The loop is filled using ahigh flow vacuum pump. Once the loop isfilled the valve is switched and the sampleis pushed to the nebulizer by a carrier flowof dilute acid. This mode of sample transferensures that the sample does not come intocontact with the peristaltic pump tubing,removing a major cause of sample carry-over and blank contamination. Keeping thedistance from the loop to the nebulizer shortprovides a rapid rise to steady state signaland once the analysis is complete,

switching the valve produces a rapid returnto baseline, dramatically reducing bothuptake and rinse times. During sampleanalysis the autosampler sends the probe tothe rinse station for cleaning and then movesit to wait over the next sample, saving onautosampler movement time. The low deadvolume mixing T allows high ratios of dilutionto be performed, meaning sample racks canbe transferred directly from ICP-OES to ICP-MS without any further dilution.

EmbraceConnectivity

Automation and connectivity for the highest flexibilityThermo

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The XSERIES 2 has been designed from the ground up to seamlessly support fully automated analyses aswell as to partner sophisticated hyphenated techniques.

XSERIES 2 with New Wave Laser

Screen capture from the New Wave laser ablation software showinganalysis points that are automatically linked to analyses inside PlasmaLab

1 New Wave Research™, Fremont CA (a Division of ESI).

LA-ICP-MSCoupling the XSERIES 2 with a Laser Ablation system provides apowerful tool for the multi-elemental analysis of both conductingand non-conducting solids in a range of applications.

Not only can the laser and ICP-MS software run on the samePC but, uniquely, the XSERIES 2 requires no additional cabling oradditional configuration for triggered LA-ICP-MS analyses.

‘Laser Patterns’ defined in the New Wave1 laser software areautomatically assigned to analyses in PlasmaLab’s ‘Sample List’.With this level of integration, Laser Ablation analyses can be assimple to set up as an autosampler.

The data transfer between the two systems is fully bidirectionalallowing for fail-safe automated analyses, important when precioussamples (e.g. zircons etc.) would otherwise be needlessly ablated.

External calibration of 24Mg in polymers by LA-ICP-MS

GC-ICP-MSCoupling capillary GC with the XSERIES 2 offers outstandingseparation power with rapid, sensitive detection for thedetermination of ultra-trace elemental species.

The XSERIES 2 GC-ICP-MS coupling kit incorporates a uniquedual mode sample introduction system. Simultaneous introductionof a liquid in parallel to the GC gas stream allows for a moreflexible approach to optimization, quantification and internalstandardization whilst maintaining a robust wet plasma.

Volatile elemental species, separated by GC, are transferred tothe plasma using a heated transfer line with the aid of a PlasmaLabcontrolled additional gas flow.

Multi-elemental GC chromatogram of Sn and Hg species, 0.5 µg/L ofeach species. Automatic peak searching and integration performedin PlasmaLab

0.1-10 ppm calibration derived from five different sulfur species

Off the shelf, pre-defined kits for all leading LC and GC devices are available for the rapid addition ofLC- and GC-ICP-MS capabilities in any laboratory. In addition to the necessary hardware, these kitsinclude application specific software for a complete instrumental package.

HPLC chromatogram of Cr(III) and Cr(VI), 2 µg/L of each species

Cr(VI) External Calibration, 0.5, 1, 2, 5 µg/L

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HPLC-ICP-MSWith the diverse range of chromatography media and ease ofcoupling, HPLC-ICP-MS remains the preferable choice for routinespeciation and research applications in a wide variety of matrices.

The XSERIES 2 HPLC-ICP-MS coupling kit offers a fullyautomated analytical solution where HPLC introduction is easilyinterchangeable with the classic ICP-MS configuration. Automationand acquisition are controlled by scripts that are readily adaptablefor the control of third party accessories including generic HPLCpumps.

Data processing of chromatographic traces is performed usingautomatic peak searches with user definable peak integration features.Integration parameters can be applied to other isotopes offering multi-isotopic quantification as well as isotope ratio information.

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©2008 Thermo Fisher Scientific Inc. Windows is aregistered trademark of Microsoft Corporation in theUnited States and possibly other countries. SC FAST is aregistered trademark of Elemental Scientific Inc. in theUnited States and possibly other countries. All rightsreserved. All other trademarks are the property ofThermo Fisher Scientific Inc. and its subsidiaries.

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Thermo Fisher Scientific (Bremen) GmbHis certified DIN EN ISO 9001:2000

The use of an Inductively Coupled Plasmasource (ICP) is the accepted and mostpowerful technique for the analysis andquantification of trace elements in bothsolid and liquid samples. Its applicationsrange from routine environmental analysesto the materials industry, geologicalapplications to clinical research and fromthe food industry to the semiconductorindustry.

Thermo Fisher Scientific is the onlyinstrument manufacturer to offer the fullrange of Inductively Coupled PlasmaSpectrometers (ICP, Quadrupole and SectorICP-MS) to satisfy every aspect of plasmaspectrometry from routine to highlydemanding research applications.

Develop your lab from the easy-to-useiCAP ICP to the high performance XSERIES 2Quadrupole ICP-MS and up to the ultra-sophisticated ELEMENT 2/XR and NEPTUNESector Field ICP-MS instruments. Eachinstrument combines leading-edgetechnology, fit for purpose and affordabilitywith a tradition of quality, longevity,accuracy and ease of use.

Plasma Capabilities from Thermo Fisher Scientific

Thermo ScientificELEMENT 2/XR Sector Field ICP-MS

Thermo ScientificXSERIES 2 ICP-MS

Thermo ScientificiCAP ICP

Thermo ScientificNEPTUNE Multicollector ICP-MS