Thangapazham RL, Sharma A, Maheshwari RK. Links Multiple ...ummafrapp.de/krebs/Curcumin/Curcumin and Cancer-1.pdf · 2: Kamath R, Jiang Z, Sun G, Yalowich JC, Rajasekaran B. Related

: Thangapazham RL, Sharma A, Maheshwari RK. Related Articles, Links Multiple molecular targets in cancer chemoprevention by curcumin.AAPS J. 2006 Jul 7;8(3):E443-9. PMID: 17025261 [PubMed - in process]

2: Kamath R, Jiang Z, Sun G, Yalowich JC, Rajasekaran B. Related Articles, Links c-Abl kinase regulates curcumin-induced cell death through activation of JNK.Mol Pharmacol. 2006 Oct 4; [Epub ahead of print] PMID: 17021249 [PubMed - as supplied by publisher]

3: Wang X, Wang Q, Ives KL, Evers BM. Related Articles, Links Curcumin inhibits neurotensin-mediated interleukin-8 production and migration of HCT116 human colon cancer cells.Clin Cancer Res. 2006 Sep 15;12(18):5346-55. PMID: 17000667 [PubMed - in process]

4: Sharma C, Kaur J, Shishodia S, Aggarwal BB, Ralhan R. Related Articles, Links Curcumin down regulates smokeless tobacco-induced NF-kappaB activation and COX-2 expression in human oral premalignant and cancer cells.Toxicology. 2006 Aug 12; [Epub ahead of print] PMID: 16996673 [PubMed - as supplied by publisher]

5: Bemis DL, Katz AE, Buttyan R. Related Articles, Links Clinical trials of natural products as chemopreventive agents for prostate cancer.Expert Opin Investig Drugs. 2006 Oct;15(10):1191-200. PMID: 16989596 [PubMed - in process]

6: Khanbolooki S, Nawrocki ST, Arumugam T, Andtbacka R, Pino MS, Kurzrock R, Logsdon CD, Abbruzzese JL, McConkey DJ.

Related Articles, Links

Nuclear factor-kappaB maintains TRAIL resistance in human pancreatic cancer cells.Mol Cancer Ther. 2006 Sep;5(9):2251-60. PMID: 16985059 [PubMed - in process]

7: Ruiz-Torres MP, Perez-Rivero G, Diez-Marques ML, Griera M, Ortega R, Rodriguez-Puyol M, Rodriguez-Puyol D.


Role of activator protein-1 on the effect of arginine-glycine-aspartic acid containing peptides on transforming growth factor-beta1 promoter activity.Int J Biochem Cell Biol. 2006 Aug 18; [Epub ahead of print] PMID: 16978906 [PubMed - as supplied by publisher]

8: Chen J, Bai H, Wang C, Kang J. Related Articles, Links Trichostatin A improves the anticancer activity of low concentrations of curcumin in human leukemia cells.Pharmazie. 2006 Aug;61(8):710-6. PMID: 16964716 [PubMed - indexed for MEDLINE]

9: Limtrakul P, Chearwae W, Shukla S, Phisalphong C, Ambudkar SV. Related Articles, Links Modulation of function of three ABC drug transporters, P-glycoprotein (ABCB1), mitoxantrone resistance protein (ABCG2) and multidrug resistance protein 1 (ABCC1) by tetrahydrocurcumin, a major metabolite of curcumin.Mol Cell Biochem. 2006 Sep 8; [Epub ahead of print] PMID: 16960658 [PubMed - as supplied by publisher]

10: Singh RP, Agarwal R. Related Articles, Links Mechanisms of action of novel agents for prostate cancer chemoprevention.Endocr Relat Cancer. 2006 Sep;13(3):751-78. PMID: 16954429 [PubMed - in process]

11: Niture SK, Velu CS, Smith QR, Bhat GJ, Srivenugopal KS. Related Articles, Links Increased expression of the MGMT repair protein mediated by cysteine prodrugs and chemopreventative natural products in human lymphocytes and tumor cell lines.Carcinogenesis. 2006 Aug 31; [Epub ahead of print] PMID: 16950796 [PubMed - as supplied by publisher]

12: Chearwae W, Shukla S, Limtrakul P, Ambudkar SV. Related Articles, Links Modulation of the function of the multidrug resistance-linked ATP-binding cassette transporter ABCG2 by the cancer chemopreventive agent curcumin.

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Mol Cancer Ther. 2006 Aug;5(8):1995-2006. PMID: 16928820 [PubMed - in process]

13: Choi H, Chun YS, Kim SW, Kim MS, Park JW. Related Articles, Links Curcumin inhibits hypoxia-inducible factor-1 by degrading aryl hydrocarbon receptor nuclear translocator: A mechanism of tumor growth inhibition.Mol Pharmacol. 2006 Jul 31; [Epub ahead of print] PMID: 16880289 [PubMed - as supplied by publisher]

14: Wu Q, Chen Y, Li X. Related Articles, Links HDAC1 expression and effect of curcumin on proliferation of Raji cells.J Huazhong Univ Sci Technolog Med Sci. 2006;26(2):199-201, 210. PMID: 16850746 [PubMed - in process]

15: Wolanin K, Magalska A, Mosieniak G, Klinger R, McKenna S, Vejda S, Sikora E, Piwocka K.


Curcumin affects components of the chromosomal passenger complex and induces mitotic catastrophe in apoptosis-resistant Bcr-Abl-expressing cells.Mol Cancer Res. 2006 Jul;4(7):457-69. PMID: 16849521 [PubMed - indexed for MEDLINE]

16: Lang S, Picu A, Hofmann T, Andratschke M, Mack B, Moosmann A, Gires O, Tiwari S, Zeidler R.


COX-inhibitors relieve the immunosuppressive effect of tumor cells and improve functions of immune effectors.Int J Immunopathol Pharmacol. 2006 Apr-Jun;19(2):409-19. PMID: 16831307 [PubMed - indexed for MEDLINE]

17: Cui SX, Qu XJ, Xie YY, Zhou L, Nakata M, Makuuchi M, Tang W. Related Articles, Links Curcumin inhibits telomerase activity in human cancer cell lines.Int J Mol Med. 2006 Aug;18(2):227-31. PMID: 16820928 [PubMed - in process]

18: Naganuma M, Saruwatari A, Okamura S, Tamura H. Related Articles, Links Turmeric and curcumin modulate the conjugation of 1-naphthol in Caco-2 cells.Biol Pharm Bull. 2006 Jul;29(7):1476-9. PMID: 16819192 [PubMed - indexed for MEDLINE]

19: Moon DO, Jin CY, Lee JD, Choi YH, Ahn SC, Lee CM, Jeong SC, Park YM, Kim GY.


Curcumin decreases binding of Shiga-like toxin-1B on human intestinal epithelial cell line HT29 stimulated with TNF-alpha and IL-1beta: suppression of p38, JNK and NF-kappaB p65 as potential targets.Biol Pharm Bull. 2006 Jul;29(7):1470-5. PMID: 16819191 [PubMed - indexed for MEDLINE]

20: Zheng LD, Tong QS, Wu CH. Related Articles, Links Growth inhibition and apoptosis inducing mechanisms of curcumin on human ovarian cancer cell line a2780.Chin J Integr Med. 2006 Jun;12(2):126-31. PMID: 16800992 [PubMed - in process]

21: Lin L, Shi Q, Nyarko AK, Bastow KF, Wu CC, Su CY, Shih CC, Lee KH. Related Articles, Links Antitumor agents. 250. Design and synthesis of new curcumin analogues as potential anti-prostate cancer agents.J Med Chem. 2006 Jun 29;49(13):3963-72. PMID: 16789753 [PubMed - indexed for MEDLINE]

22: Marcu MG, Jung YJ, Lee S, Chung EJ, Lee MJ, Trepel J, Neckers L. Related Articles, Links Curcumin is an inhibitor of p300 histone acetylatransferase.Med Chem. 2006 Mar;2(2):169-74. PMID: 16787365 [PubMed - indexed for MEDLINE]

23: Zhang M, Deng C, Zheng J, Xia J, Sheng D. Related Articles, Links Curcumin inhibits trinitrobenzene sulphonic acid-induced colitis in rats by activation of peroxisome proliferator-activated receptor gamma.


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http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=16789753&itool=iconabstr&query_hl=1&itool=pubmed_DocSum



Int Immunopharmacol. 2006 Aug;6(8):1233-42. Epub 2006 Apr 7. PMID: 16782535 [PubMed - indexed for MEDLINE]

24: Kachadourian R, Day BJ. Related Articles, Links Flavonoid-induced glutathione depletion: potential implications for cancer treatment.Free Radic Biol Med. 2006 Jul 1;41(1):65-76. Epub 2006 Mar 31. PMID: 16781454 [PubMed - indexed for MEDLINE]

25: Belkaid A, Copland IB, Massillon D, Annabi B. Related Articles, Links Silencing of the human microsomal glucose-6-phosphate translocase induces glioma cell death: potential new anticancer target for curcumin.FEBS Lett. 2006 Jun 26;580(15):3746-52. Epub 2006 Jun 9. PMID: 16777101 [PubMed - indexed for MEDLINE]

26: Barasch A, Elad S, Altman A, Damato K, Epstein J. Related Articles, Links Antimicrobials, mucosal coating agents, anesthetics, analgesics, and nutritional supplements for alimentary tract mucositis.Support Care Cancer. 2006 Jun;14(6):528-32. Epub 2006 May 4. Review. PMID: 16775648 [PubMed - indexed for MEDLINE]

27: Cruz-Correa M, Shoskes DA, Sanchez P, Zhao R, Hylind LM, Wexner SD, Giardiello FM.


Combination treatment with curcumin and quercetin of adenomas in familial adenomatous polyposis.Clin Gastroenterol Hepatol. 2006 Aug;4(8):1035-8. Epub 2006 Jun 6. PMID: 16757216 [PubMed - in process]

28: Lev-Ari S, Maimon Y, Strier L, Kazanov D, Arber N. Related Articles, Links Down-regulation of prostaglandin E2 by curcumin is correlated with inhibition of cell growth and induction of apoptosis in human colon carcinoma cell lines.J Soc Integr Oncol. 2006 Winter;4(1):21-6. PMID: 16737669 [PubMed - indexed for MEDLINE]

29: [No authors listed] Related Articles, Links Complementary modalities for breast and gastrointestinal cancer.J Soc Integr Oncol. 2005 Dec 1;3(4):150-4. PMID: 16737655 [PubMed - in process]

30: Jankun J, Aleem AM, Malgorzewicz S, Szkudlarek M, Zavodszky MI, Dewitt DL, Feig M, Selman SH, Skrzypczak-Jankun E.


Synthetic curcuminoids modulate the arachidonic acid metabolism of human platelet 12-lipoxygenase and reduce sprout formation of human endothelial cells.Mol Cancer Ther. 2006 May;5(5):1371-82. PMID: 16731771 [PubMed - indexed for MEDLINE]

31: Sun A, Shoji M, Lu YJ, Liotta DC, Snyder JP. Related Articles, Links Synthesis of EF24-tripeptide chloromethyl ketone: a novel curcumin-related anticancer drug delivery system.J Med Chem. 2006 Jun 1;49(11):3153-8. PMID: 16722634 [PubMed - indexed for MEDLINE]

32: Magalska A, Sliwinska M, Szczepanowska J, Salvioli S, Franceschi C, Sikora E.


Resistance to apoptosis of HCW-2 cells can be overcome by curcumin- or vincristine-induced mitotic catastrophe.Int J Cancer. 2006 Oct 15;119(8):1811-8. PMID: 16721786 [PubMed - in process]

33: Wright TI, Spencer JM, Flowers FP. Related Articles, Links Chemoprevention of nonmelanoma skin cancer.J Am Acad Dermatol. 2006 Jun;54(6):933-46; quiz 947-50. Review. PMID: 16713450 [PubMed - indexed for MEDLINE]

34: Singh S, Khar A. Related Articles, Links Biological effects of curcumin and its role in cancer chemoprevention and therapy.Anticancer Agents Med Chem. 2006 May;6(3):259-70. Review. PMID: 16712454 [PubMed - indexed for MEDLINE]





































35: Schindler R, Mentlein R. Related Articles, Links Flavonoids and vitamin E reduce the release of the angiogenic peptide vascular endothelial growth factor from human tumor cells.J Nutr. 2006 Jun;136(6):1477-82. PMID: 16702307 [PubMed - indexed for MEDLINE]

36: Atsumi T, Tonosaki K, Fujisawa S. Related Articles, Links Induction of early apoptosis and ROS-generation activity in human gingival fibroblasts (HGF) and human submandibular gland carcinoma (HSG) cells treated with curcumin.Arch Oral Biol. 2006 Oct;51(10):913-21. Epub 2006 May 15. PMID: 16697971 [PubMed - in process]

37: Lu P, Tong Q, Jiang F, Zheng L, Chen F, Zeng F, Dong J, Du Y. Related Articles, Links Preparation of curcumin prodrugs and their in vitro anti-tumor activities.J Huazhong Univ Sci Technolog Med Sci. 2005;25(6):668-70, 678. PMID: 16696321 [PubMed - in process]

38: Lee J, Jung HH, Im YH, Kim JH, Park JO, Kim K, Kim WS, Ahn JS, Jung CW, Park YS, Kang WK, Park K.


Interferon-alpha resistance can be reversed by inhibition of IFN-alpha-induced COX-2 expression potentially via STAT1 activation in A549 cells.Oncol Rep. 2006 Jun;15(6):1541-9. PMID: 16685393 [PubMed - in process]

39: Chirnomas D, Taniguchi T, de la Vega M, Vaidya AP, Vasserman M, Hartman AR, Kennedy R, Foster R, Mahoney J, Seiden MV, D'Andrea AD.


Chemosensitization to cisplatin by inhibitors of the Fanconi anemia/BRCA pathway.Mol Cancer Ther. 2006 Apr;5(4):952-61. PMID: 16648566 [PubMed - indexed for MEDLINE]

40: Sikora E, Bielak-Zmijewska A, Magalska A, Piwocka K, Mosieniak G, Kalinowska M, Widlak P, Cymerman IA, Bujnicki JM.


Curcumin induces caspase-3-dependent apoptotic pathway but inhibits DNA fragmentation factor 40/caspase-activated DNase endonuclease in human Jurkat cells.Mol Cancer Ther. 2006 Apr;5(4):927-34. PMID: 16648563 [PubMed - indexed for MEDLINE]

41: Liu H, Danthi SJ, Enyeart JJ. Related Articles, Links Curcumin potently blocks Kv1.4 potassium channels.Biochem Biophys Res Commun. 2006 Jun 16;344(4):1161-5. PMID: 16647042 [PubMed - indexed for MEDLINE]

42: Kang SK, Cha SH, Jeon HG. Related Articles, Links

Curcumin-induced histone hypoacetylation enhances caspase-3-dependent glioma cell death and neurogenesis of neural progenitor cells.Stem Cells Dev. 2006 Apr;15(2):165-74. PMID: 16646663 [PubMed - indexed for MEDLINE]

43: Chakravarti N, Myers JN, Aggarwal BB. Related Articles, Links Targeting constitutive and interleukin-6-inducible signal transducers and activators of transcription 3 pathway in head and neck squamous cell carcinoma cells by curcumin (diferuloylmethane).Int J Cancer. 2006 Sep 15;119(6):1268-75. PMID: 16642480 [PubMed - indexed for MEDLINE]

44: Tomita M, Matsuda T, Kawakami H, Uchihara JN, Okudaira T, Masuda M, Ohshiro K, Mori N.


Curcumin targets Akt cell survival signaling pathway in HTLV-I-infected T-cell lines.Cancer Sci. 2006 Apr;97(4):322-7. PMID: 16630125 [PubMed - indexed for MEDLINE]

45: Wang Z, Zhang Y, Banerjee S, Li Y, Sarkar FH. Related Articles, Links





































Notch-1 down-regulation by curcumin is associated with the inhibition of cell growth and the induction of apoptosis in pancreatic cancer cells.Cancer. 2006 Jun 1;106(11):2503-13. PMID: 16628653 [PubMed - indexed for MEDLINE]

46: Su CC, Chen GW, Lin JG, Wu LT, Chung JG. Related Articles, Links Curcumin inhibits cell migration of human colon cancer colo 205 cells through the inhibition of nuclear factor kappa B /p65 and down-regulates cyclooxygenase-2 and matrix metalloproteinase-2 expressions.Anticancer Res. 2006 Mar-Apr;26(2A):1281-8. PMID: 16619535 [PubMed - indexed for MEDLINE]

47: Park C, Kim GY, Kim GD, Choi BT, Park YM, Choi YH. Related Articles, Links Induction of G2/M arrest and inhibition of cyclooxygenase-2 activity by curcumin in human bladder cancer T24 cells.Oncol Rep. 2006 May;15(5):1225-31. PMID: 16596191 [PubMed - indexed for MEDLINE]

48: Pesic M, Markovic JZ, Jankovic D, Kanazir S, Markovic ID, Rakic L, Ruzdijic S.


Induced resistance in the human non small cell lung carcinoma (NCI-H460) cell line in vitro by anticancer drugs.J Chemother. 2006 Feb;18(1):66-73. PMID: 16572896 [PubMed - indexed for MEDLINE]

49: Skommer J, Wlodkowic D, Pelkonen J. Related Articles, Links Cellular foundation of curcumin-induced apoptosis in follicular lymphoma cell lines.Exp Hematol. 2006 Apr;34(4):463-74. PMID: 16569593 [PubMed - indexed for MEDLINE]

50: Koon H, Leung AW, Yue KK, Mak NK. Related Articles, Links Photodynamic Effect of Curcumin on NPC/CNE2 Cells.J Environ Pathol Toxicol Oncol. 2006;25(1-2):205-16. PMID: 16566718 [PubMed - in process]

51: Aggarwal BB, Shishodia S. Related Articles, Links Molecular targets of dietary agents for prevention and therapy of cancer.Biochem Pharmacol. 2006 May 14;71(10):1397-421. Epub 2006 Feb 23. Review. PMID: 16563357 [PubMed - indexed for MEDLINE]

52: HemaIswarya S, Doble M. Related Articles, Links Potential synergism of natural products in the treatment of cancer.Phytother Res. 2006 Apr;20(4):239-49. Review. PMID: 16557604 [PubMed - indexed for MEDLINE]

53: Campbell FC, Collett GP. Related Articles, Links Chemopreventive properties of curcumin.Future Oncol. 2005 Jun;1(3):405-14. PMID: 16556014 [PubMed - indexed for MEDLINE]

54: Beevers CS, Li F, Liu L, Huang S. Related Articles, Links Curcumin inhibits the mammalian target of rapamycin-mediated signaling pathways in cancer cells.Int J Cancer. 2006 Aug 15;119(4):757-64. PMID: 16550606 [PubMed - indexed for MEDLINE]

55: Kwak HJ, Park MJ, Cho H, Park CM, Moon SI, Lee HC, Park IC, Kim MS, Rhee CH, Hong SI.


Transforming growth factor-beta1 induces tissue inhibitor of metalloproteinase-1 expression via activation of extracellular signal-regulated kinase and Sp1 in human fibrosarcoma cells.Mol Cancer Res. 2006 Mar;4(3):209-20. PMID: 16547158 [PubMed - indexed for MEDLINE]

56: Jiao Y, Wilkinson J 4th, Christine Pietsch E, Buss JL, Wang W, Planalp R, Torti FM, Torti SV.






































Iron chelation in the biological activity of curcumin.Free Radic Biol Med. 2006 Apr 1;40(7):1152-60. PMID: 16545682 [PubMed - indexed for MEDLINE]

57: Lao CD, Ruffin MT 4th, Normolle D, Heath DD, Murray SI, Bailey JM, Boggs ME, Crowell J, Rock CL, Brenner DE.


Dose escalation of a curcuminoid formulation.BMC Complement Altern Med. 2006 Mar 17;6:10. PMID: 16545122 [PubMed - indexed for MEDLINE]

58: Yoysungnoen P, Wirachwong P, Bhattarakosol P, Niimi H, Patumraj S. Related Articles, Links Effects of curcumin on tumor angiogenesis and biomarkers, COX-2 and VEGF, in hepatocellular carcinoma cell-implanted nude mice.Clin Hemorheol Microcirc. 2006;34(1-2):109-15. PMID: 16543625 [PubMed - indexed for MEDLINE]

59: Jones SB, Brooks JD. Related Articles, Links Modest induction of phase 2 enzyme activity in the F-344 rat prostate.BMC Cancer. 2006 Mar 15;6:62. PMID: 16539699 [PubMed - indexed for MEDLINE]

60: Indap MA, Radhika S, Motiwale L, Rao KV. Related Articles, Links Inhibitory effect of cinnamoyl compounds against human malignant cell line.Indian J Exp Biol. 2006 Mar;44(3):216-20. PMID: 16538860 [PubMed - indexed for MEDLINE]

61: Cao J, Jia L, Zhou HM, Liu Y, Zhong LF. Related Articles, Links Mitochondrial and nuclear DNA damage induced by curcumin in human hepatoma G2 cells.Toxicol Sci. 2006 Jun;91(2):476-83. Epub 2006 Mar 14. PMID: 16537656 [PubMed - indexed for MEDLINE]

62: Divya CS, Pillai MR. Related Articles, Links Antitumor action of curcumin in human papillomavirus associated cells involves downregulation of viral oncogenes, prevention of NFkB and AP-1 translocation, and modulation of apoptosis.Mol Carcinog. 2006 May;45(5):320-32. PMID: 16526022 [PubMed - indexed for MEDLINE]

63: Balcerek M, Matlawska I. Related Articles, Links [Preventive role of curcumin in lung cancer]Przegl Lek. 2005;62(10):1180-1. Review. Polish. PMID: 16521985 [PubMed - indexed for MEDLINE]

64: Tong QS, Zheng LD, Lu P, Jiang FC, Chen FM, Zeng FQ, Wang L, Dong JH.


Apoptosis-inducing effects of curcumin derivatives in human bladder cancer cells.Anticancer Drugs. 2006 Mar;17(3):279-87. PMID: 16520656 [PubMed - in process]

65: Guo H, Yu JH, Chen K, Ye ZQ, Liu GC. Related Articles, Links [Curcumin-induced apoptosis in androgen-dependent prostate cancer cell line LNCaP in vitro]Zhonghua Nan Ke Xue. 2006 Feb;12(2):141-4. Chinese. PMID: 16519151 [PubMed - in process]

66: Kukongviriyapan V, Phromsopha N, Tassaneeyakul W, Kukongviriyapan U, Sripa B, Hahnvajanawong V, Bhudhisawasdi V.


Inhibitory effects of polyphenolic compounds on human arylamine N-acetyltransferase 1 and 2.Xenobiotica. 2006 Jan;36(1):15-28. PMID: 16507510 [PubMed - indexed for MEDLINE]

67: Lev-Ari S, Zinger H, Kazanov D, Yona D, Ben-Yosef R, Starr A, Figer A, Arber N.


Curcumin synergistically potentiates the growth inhibitory and pro-apoptotic effects of




























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celecoxib in pancreatic adenocarcinoma cells.Biomed Pharmacother. 2005 Oct;59 Suppl 2:S276-80. PMID: 16507392 [PubMed - indexed for MEDLINE]

68: Moussavi M, Assi K, Gomez-Munoz A, Salh B. Related Articles, Links Curcumin mediates ceramide generation via the de novo pathway in colon cancer cells.Carcinogenesis. 2006 Aug;27(8):1636-44. Epub 2006 Feb 25. PMID: 16501251 [PubMed - indexed for MEDLINE]

69: Collett GP, Campbell FC. Related Articles, Links Overexpression of p65/RelA potentiates curcumin-induced apoptosis in HCT116 human colon cancer cells.Carcinogenesis. 2006 Jun;27(6):1285-91. Epub 2006 Feb 23. PMID: 16497702 [PubMed - indexed for MEDLINE]

70: Anuchapreeda S, Limtrakul P, Thanarattanakorn P, Sittipreechacharn S, Chanarat P.


Inhibitory effect of curcumin on WT1 gene expression in patient leukemic cells.Arch Pharm Res. 2006 Jan;29(1):80-7. PMID: 16491848 [PubMed - indexed for MEDLINE]

71: [No authors listed] Related Articles, Links Spice it up: disease-fighting flavors.Consum Rep. 2006 Jan;71(1):49. No abstract available. PMID: 16491528 [PubMed - indexed for MEDLINE]

72: Sreepriya M, Bali G. Related Articles, Links Effects of administration of Embelin and Curcumin on lipid peroxidation, hepatic glutathione antioxidant defense and hematopoietic system during N-nitrosodiethylamine/Phenobarbital-induced hepatocarcinogenesis in Wistar rats.Mol Cell Biochem. 2006 Mar;284(1-2):49-55. Epub 2006 Feb 14. PMID: 16477385 [PubMed - indexed for MEDLINE]

73: Deeb DD, Jiang H, Gao X, Divine G, Dulchavsky SA, Gautam SC. Related Articles, Links Chemosensitization of hormone-refractory prostate cancer cells by curcumin to TRAIL-induced apoptosis.J Exp Ther Oncol. 2005;5(2):81-91. PMID: 16471035 [PubMed - indexed for MEDLINE]

74: Baliga MS, Katiyar SK. Related Articles, Links Chemoprevention of photocarcinogenesis by selected dietary botanicals.Photochem Photobiol Sci. 2006 Feb;5(2):243-53. Epub 2005 Aug 12. Review. PMID: 16465310 [PubMed - indexed for MEDLINE]

75: Dikshit P, Goswami A, Mishra A, Chatterjee M, Jana NR. Related Articles, Links Curcumin induces stress response, neurite outgrowth and prevent NF-kappaB activation by inhibiting the proteasome function.Neurotox Res. 2006 Jan;9(1):29-37. PMID: 16464750 [PubMed - indexed for MEDLINE]

76: Holland ML, Panetta JA, Hoskins JM, Bebawy M, Roufogalis BD, Allen JD, Arnold JC.


The effects of cannabinoids on P-glycoprotein transport and expression in multidrug resistant cells.Biochem Pharmacol. 2006 Apr 14;71(8):1146-54. Epub 2006 Feb 2. PMID: 16458258 [PubMed - indexed for MEDLINE]

77: Chakraborty S, Ghosh U, Bhattacharyya NP, Bhattacharya RK, Roy M. Related Articles, Links Inhibition of telomerase activity and induction of apoptosis by curcumin in K-562 cells.Mutat Res. 2006 Apr 11;596(1-2):81-90. Epub 2006 Jan 30. PMID: 16445949 [PubMed - indexed for MEDLINE]

78: Fujisawa S, Kadoma Y. Related Articles, Links Anti- and pro-oxidant effects of oxidized quercetin, curcumin or curcumin-related compounds with thiols or ascorbate as measured by the induction period method.In Vivo. 2006 Jan-Feb;20(1):39-44.




























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PMID: 16433026 [PubMed - indexed for MEDLINE]79: Shen G, Xu C, Hu R, Jain MR, Gopalkrishnan A, Nair S, Huang MT, Chan

JY, Kong AN.Related Articles, Links

Modulation of nuclear factor E2-related factor 2-mediated gene expression in mice liver and small intestine by cancer chemopreventive agent curcumin.Mol Cancer Ther. 2006 Jan;5(1):39-51. PMID: 16432161 [PubMed - indexed for MEDLINE]

80: Lin L, Shi Q, Su CY, Shih CC, Lee KH. Related Articles, Links Antitumor agents 247. New 4-ethoxycarbonylethyl curcumin analogs as potential antiandrogenic agents.Bioorg Med Chem. 2006 Apr 15;14(8):2527-34. Epub 2006 Jan 19. PMID: 16427289 [PubMed - indexed for MEDLINE]

Items 61 - 80 of 599

: Khor TO, Keum YS, Lin W, Kim JH, Hu R, Shen G, Xu C, Gopalakrishnan A, Reddy B, Zheng X, Conney AH, Kong AN.


Combined inhibitory effects of curcumin and phenethyl isothiocyanate on the growth of human PC-3 prostate xenografts in immunodeficient mice.Cancer Res. 2006 Jan 15;66(2):613-21. PMID: 16423986 [PubMed - indexed for MEDLINE]

82: Gao X, Deeb D, Jiang H, Liu YB, Dulchavsky SA, Gautam SC. Related Articles, Links Curcumin differentially sensitizes malignant glioma cells to TRAIL/Apo2L-mediated apoptosis through activation of procaspases and release of cytochrome c from mitochondria.J Exp Ther Oncol. 2005;5(1):39-48. PMID: 16416600 [PubMed - indexed for MEDLINE]

83: Barta I, Smerak P, Polivkova Z, Sestakova H, Langova M, Turek B, Bartova J.


Current trends and perspectives in nutrition and cancer prevention.Neoplasma. 2006;53(1):19-25. PMID: 16416008 [PubMed - indexed for MEDLINE]

84: Maheshwari RK, Singh AK, Gaddipati J, Srimal RC. Related Articles, Links Multiple biological activities of curcumin: a short review.Life Sci. 2006 Mar 27;78(18):2081-7. Epub 2006 Jan 18. Review. PMID: 16413584 [PubMed - indexed for MEDLINE]

85: Eckert RL, Crish JF, Efimova T, Balasubramanian S. Related Articles, Links Opposing action of curcumin and green tea polyphenol in human keratinocytes.Mol Nutr Food Res. 2006 Feb;50(2):123-9. Review. PMID: 16404707 [PubMed - indexed for MEDLINE]

86: Huang YT, Huang DM, Chueh SC, Teng CM, Guh JH. Related Articles, Links Alisol B acetate, a triterpene from Alismatis rhizoma, induces Bax nuclear translocation and apoptosis in human hormone-resistant prostate cancer PC-3 cells.Cancer Lett. 2006 Jan 18;231(2):270-8. PMID: 16399228 [PubMed - indexed for MEDLINE]

87: Guo F, Xu CJ. Related Articles, Links [Progress on the study of mechanism of the direct action of TCM bioactive components on ovarian cancer]Zhongguo Zhong Xi Yi Jie He Za Zhi. 2005 Dec;25(12):1140-4. Chinese. PMID: 16398441 [PubMed - in process]

88: Hong JH, Ahn KS, Bae E, Jeon SS, Choi HY. Related Articles, Links The effects of curcumin on the invasiveness of prostate cancer in vitro and in vivo.Prostate Cancer Prostatic Dis. 2006;9(2):147-52. Epub 2006 Jan 3. PMID: 16389264 [PubMed - indexed for MEDLINE]

89: Bengmark S. Related Articles, Links Curcumin, an atoxic antioxidant and natural NFkappaB, cyclooxygenase-2, lipooxygenase, and inducible nitric oxide synthase inhibitor: a shield against acute and





































chronic diseases.JPEN J Parenter Enteral Nutr. 2006 Jan-Feb;30(1):45-51. Review. PMID: 16387899 [PubMed - indexed for MEDLINE]

90: Shishodia S, Sethi G, Aggarwal BB. Related Articles, Links Curcumin: getting back to the roots.Ann N Y Acad Sci. 2005 Nov;1056:206-17. PMID: 16387689 [PubMed - in process]

91: Tunstall RG, Sharma RA, Perkins S, Sale S, Singh R, Farmer PB, Steward WP, Gescher AJ.


Cyclooxygenase-2 expression and oxidative DNA adducts in murine intestinal adenomas: modification by dietary curcumin and implications for clinical trials.Eur J Cancer. 2006 Feb;42(3):415-21. Epub 2006 Jan 4. PMID: 16387490 [PubMed - indexed for MEDLINE]

92: Shi M, Cai Q, Yao L, Mao Y, Ming Y, Ouyang G. Related Articles, Links Antiproliferation and apoptosis induced by curcumin in human ovarian cancer cells.Cell Biol Int. 2006 Mar;30(3):221-6. Epub 2005 Dec 22. PMID: 16376585 [PubMed - indexed for MEDLINE]

93: Rajasingh J, Raikwar HP, Muthian G, Johnson C, Bright JJ. Related Articles, Links Curcumin induces growth-arrest and apoptosis in association with the inhibition of constitutively active JAK-STAT pathway in T cell leukemia.Biochem Biophys Res Commun. 2006 Feb 10;340(2):359-68. Epub 2005 Dec 13. PMID: 16364242 [PubMed - indexed for MEDLINE]

94: Kawanishi S, Oikawa S, Murata M. Related Articles, Links Evaluation for safety of antioxidant chemopreventive agents.Antioxid Redox Signal. 2005 Nov-Dec;7(11-12):1728-39. Review. PMID: 16356133 [PubMed - indexed for MEDLINE]

95: Garg AK, Buchholz TA, Aggarwal BB. Related Articles, Links Chemosensitization and radiosensitization of tumors by plant polyphenols.Antioxid Redox Signal. 2005 Nov-Dec;7(11-12):1630-47. Review. PMID: 16356126 [PubMed - indexed for MEDLINE]

96: Andreadi CK, Howells LM, Atherfold PA, Manson MM. Related Articles, Links Involvement of Nrf2, p38, B-Raf, and nuclear factor-kappaB, but not phosphatidylinositol 3-kinase, in induction of hemeoxygenase-1 by dietary polyphenols.Mol Pharmacol. 2006 Mar;69(3):1033-40. Epub 2005 Dec 14. PMID: 16354769 [PubMed - indexed for MEDLINE]

97: Eybl V, Kotyzova D, Leseticky L, Bludovska M, Koutensky J. Related Articles, Links The influence of curcumin and manganese complex of curcumin on cadmium-induced oxidative damage and trace elements status in tissues of mice.J Appl Toxicol. 2006 May-Jun;26(3):207-12. PMID: 16345010 [PubMed - indexed for MEDLINE]

98: Yang L, Zhang LY, Chen WW, Kong F, Zhang PJ, Hu XY, Zhang JY, Cui FA.


[Inhibition of the expression of prostate specific antigen by curcumin]Yao Xue Xue Bao. 2005 Sep;40(9):800-3. Chinese. PMID: 16342680 [PubMed - in process]

99: Du B, Jiang L, Xia Q, Zhong L. Related Articles, Links Synergistic inhibitory effects of curcumin and 5-fluorouracil on the growth of the human colon cancer cell line HT-29.Chemotherapy. 2006;52(1):23-8. Epub 2005 Dec 9. PMID: 16340194 [PubMed - indexed for MEDLINE]

100: Weber WM, Hunsaker LA, Roybal CN, Bobrovnikova-Marjon EV, Abcouwer SF, Royer RE, Deck LM, Vander Jagt DL.


Activation of NFkappaB is inhibited by curcumin and related enones.Bioorg Med Chem. 2006 Apr 1;14(7):2450-61. Epub 2005 Dec 7. PMID: 16338138 [PubMed - indexed for MEDLINE]





































101: Edwards T. Related Articles, Links Inflammation, pain, and chronic disease: an integrative approach to treatment and prevention.Altern Ther Health Med. 2005 Nov-Dec;11(6):20-7; quiz 28, 75. Review. PMID: 16320856 [PubMed - indexed for MEDLINE]

102: Atsumi T, Murakami Y, Shibuya K, Tonosaki K, Fujisawa S. Related Articles, Links Induction of cytotoxicity and apoptosis and inhibition of cyclooxygenase-2 gene expression, by curcumin and its analog, alpha-diisoeugenol.Anticancer Res. 2005 Nov-Dec;25(6B):4029-36. PMID: 16309195 [PubMed - indexed for MEDLINE]

103: Song G, Mao YB, Cai QF, Yao LM, Ouyang GL, Bao SD. Related Articles, Links Curcumin induces human HT-29 colon adenocarcinoma cell apoptosis by activating p53 and regulating apoptosis-related protein expression.Braz J Med Biol Res. 2005 Dec;38(12):1791-8. Epub 2005 Nov 9. PMID: 16302093 [PubMed - indexed for MEDLINE]

104: Kim JH, Xu C, Keum YS, Reddy B, Conney A, Kong AN. Related Articles, Links Inhibition of EGFR signaling in human prostate cancer PC-3 cells by combination treatment with beta-phenylethyl isothiocyanate and curcumin.Carcinogenesis. 2006 Mar;27(3):475-82. Epub 2005 Nov 19. PMID: 16299382 [PubMed - indexed for MEDLINE]

105: Valentine SP, Le Nedelec MJ, Menzies AR, Scandlyn MJ, Goodin MG, Rosengren RJ.


Curcumin modulates drug metabolizing enzymes in the female Swiss Webster mouse.Life Sci. 2006 Apr 11;78(20):2391-8. Epub 2005 Nov 16. PMID: 16297412 [PubMed - indexed for MEDLINE]

106: Wax A, Pyhtila JW, Graf RN, Nines R, Boone CW, Dasari RR, Feld MS, Steele VE, Stoner GD.


Prospective grading of neoplastic change in rat esophagus epithelium using angle-resolved low-coherence interferometry.J Biomed Opt. 2005 Sep-Oct;10(5):051604. PMID: 16292952 [PubMed - indexed for MEDLINE]

107: Hu M, Du Q, Vancurova I, Lin X, Miller EJ, Simms HH, Wang P. Related Articles, Links Proapoptotic effect of curcumin on human neutrophils: activation of the p38 mitogen-activated protein kinase pathway.Crit Care Med. 2005 Nov;33(11):2571-8. PMID: 16276182 [PubMed - indexed for MEDLINE]

108: Cole GM, Lim GP, Yang F, Teter B, Begum A, Ma Q, Harris-White ME, Frautschy SA.


Prevention of Alzheimer's disease: Omega-3 fatty acid and phenolic anti-oxidant interventions.Neurobiol Aging. 2005 Dec;26 Suppl 1:133-6. Epub 2005 Nov 2. Review. PMID: 16266772 [PubMed - indexed for MEDLINE]

109: D'Incalci M, Steward WP, Gescher AJ. Related Articles, Links Use of cancer chemopreventive phytochemicals as antineoplastic agents.Lancet Oncol. 2005 Nov;6(11):899-904. PMID: 16257798 [PubMed - indexed for MEDLINE]

110: Kim H, Park BS, Lee KG, Choi CY, Jang SS, Kim YH, Lee SE. Related Articles, Links Effects of naturally occurring compounds on fibril formation and oxidative stress of beta-amyloid.J Agric Food Chem. 2005 Nov 2;53(22):8537-41. PMID: 16248550 [PubMed - indexed for MEDLINE]

111: Aggarwal BB, Shishodia S, Takada Y, Banerjee S, Newman RA, Bueso-Ramos CE, Price JE.


Curcumin suppresses the paclitaxel-induced nuclear factor-kappaB pathway in breast cancer cells and inhibits lung metastasis of human breast cancer in nude mice.





























http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=16302093&itool=iconfft&query_hl=1&itool=pubmed_DocSum









Clin Cancer Res. 2005 Oct 15;11(20):7490-8. PMID: 16243823 [PubMed - indexed for MEDLINE]

112: Yang X, Thomas DP, Zhang X, Culver BW, Alexander BM, Murdoch WJ, Rao MN, Tulis DA, Ren J, Sreejayan N.


Curcumin inhibits platelet-derived growth factor-stimulated vascular smooth muscle cell function and injury-induced neointima formation.Arterioscler Thromb Vasc Biol. 2006 Jan;26(1):85-90. Epub 2005 Oct 20. PMID: 16239599 [PubMed - indexed for MEDLINE]

113: Aggarwal S, Ichikawa H, Takada Y, Sandur SK, Shishodia S, Aggarwal BB.


Curcumin (diferuloylmethane) down-regulates expression of cell proliferation and antiapoptotic and metastatic gene products through suppression of IkappaBalpha kinase and Akt activation.Mol Pharmacol. 2006 Jan;69(1):195-206. Epub 2005 Oct 11. PMID: 16219905 [PubMed - indexed for MEDLINE]

114: Bauvois B, Dauzonne D. Related Articles, Links Aminopeptidase-N/CD13 (EC 3.4.11.2) inhibitors: chemistry, biological evaluations, and therapeutic prospects.Med Res Rev. 2006 Jan;26(1):88-130. Review. PMID: 16216010 [PubMed - indexed for MEDLINE]

115: LoTempio MM, Veena MS, Steele HL, Ramamurthy B, Ramalingam TS, Cohen AN, Chakrabarti R, Srivatsan ES, Wang MB.


Curcumin suppresses growth of head and neck squamous cell carcinoma.Clin Cancer Res. 2005 Oct 1;11(19 Pt 1):6994-7002. PMID: 16203793 [PubMed - indexed for MEDLINE]

116: Bemis DL, Capodice JL, Anastasiadis AG, Katz AE, Buttyan R. Related Articles, Links Zyflamend, a unique herbal preparation with nonselective COX inhibitory activity, induces apoptosis of prostate cancer cells that lack COX-2 expression.Nutr Cancer. 2005;52(2):202-12. PMID: 16201851 [PubMed - indexed for MEDLINE]

117: Polytarchou C, Hatziapostolou M, Papadimitriou E. Related Articles, Links Hydrogen peroxide stimulates proliferation and migration of human prostate cancer cells through activation of activator protein-1 and up-regulation of the heparin affin regulatory peptide gene.J Biol Chem. 2005 Dec 9;280(49):40428-35. Epub 2005 Sep 30. PMID: 16199533 [PubMed - indexed for MEDLINE]

118: Kim SY, Jung SH, Kim HS. Related Articles, Links Curcumin is a potent broad spectrum inhibitor of matrix metalloproteinase gene expression in human astroglioma cells.Biochem Biophys Res Commun. 2005 Nov 18;337(2):510-6. Epub 2005 Sep 21. PMID: 16198311 [PubMed - indexed for MEDLINE]

119: Nagai S, Kurimoto M, Washiyama K, Hirashima Y, Kumanishi T, Endo S. Related Articles, Links Inhibition of cellular proliferation and induction of apoptosis by curcumin in human malignant astrocytoma cell lines.J Neurooncol. 2005 Sep;74(2):105-11. PMID: 16193380 [PubMed - indexed for MEDLINE]

120: Pal S, Bhattacharyya S, Choudhuri T, Datta GK, Das T, Sa G. Related Articles, Links Amelioration of immune cell number depletion and potentiation of depressed detoxification system of tumor-bearing mice by curcumin.Cancer Detect Prev. 2005;29(5):470-8. Epub 2005 Sep 26. PMID: 16188398 [PubMed - indexed for MEDLINE]

121: Kim K, Ryu K, Ko Y, Park C. Related Articles, Links Effects of nuclear factor-kappaB inhibitors and its implication on natural killer T-cell lymphoma cells.Br J Haematol. 2005 Oct;131(1):59-66.


































PMID: 16173963 [PubMed - indexed for MEDLINE]122: Chen A, Xu J, Johnson AC. Related Articles, Links

Curcumin inhibits human colon cancer cell growth by suppressing gene expression of epidermal growth factor receptor through reducing the activity of the transcription factor Egr-1.Oncogene. 2006 Jan 12;25(2):278-87. PMID: 16170359 [PubMed - indexed for MEDLINE]

123: Lev-Ari S, Strier L, Kazanov D, Madar-Shapiro L, Dvory-Sobol H, Pinchuk I, Marian B, Lichtenberg D, Arber N.


Celecoxib and curcumin synergistically inhibit the growth of colorectal cancer cells.Clin Cancer Res. 2005 Sep 15;11(18):6738-44. PMID: 16166455 [PubMed - indexed for MEDLINE]

124: Tomita M, Kawakami H, Uchihara JN, Okudaira T, Masuda M, Takasu N, Matsuda T, Ohta T, Tanaka Y, Mori N.


Curcumin suppresses constitutive activation of AP-1 by downregulation of JunD protein in HTLV-1-infected T-cell lines.Leuk Res. 2006 Mar;30(3):313-21. Epub 2005 Sep 12. PMID: 16157375 [PubMed - indexed for MEDLINE]

125: Yoysungnoen P, Wirachwong P, Bhattarakosol P, Niimi H, Patumraj S. Related Articles, Links Antiangiogenic activity of curcumin in hepatocellular carcinoma cells implanted nude mice.Clin Hemorheol Microcirc. 2005;33(2):127-35. PMID: 16151260 [PubMed - indexed for MEDLINE]

126: Starr AN, Vexler A, Marmor S, Konik D, Ashkenasi-Voghera M, Lev-Ari S, Greif Y, Ben-Yosef R.


Establishment and characterization of a pancreatic carcinoma cell line derived from malignant pleural effusion.Oncology. 2005;69(3):239-45. Epub 2005 Sep 2. PMID: 16141719 [PubMed - indexed for MEDLINE]

127: Shen F, Fan X, Liu B, Jia X, Du H, You B, Ye M, Huang C, Shi X. Related Articles, Links Overexpression of cyclin D1-CDK4 in silica-induced transformed cells is due to activation of ERKs, JNKs/AP-1 pathway.Toxicol Lett. 2006 Jan 25;160(3):185-95. Epub 2005 Aug 25. PMID: 16125882 [PubMed - indexed for MEDLINE]

128: Kalpana C, Rajasekharan KN, Menon VP. Related Articles, Links Modulatory effects of curcumin and curcumin analog on circulatory lipid profiles during nicotine-induced toxicity in Wistar rats.J Med Food. 2005 Summer;8(2):246-50. PMID: 16117619 [PubMed - indexed for MEDLINE]

129: Venkateswarlu S, Ramachandra MS, Subbaraju GV. Related Articles, Links Synthesis and biological evaluation of polyhydroxycurcuminoids.Bioorg Med Chem. 2005 Dec 1;13(23):6374-80. Epub 2005 Aug 19. PMID: 16112582 [PubMed - indexed for MEDLINE]

130: Tomita M, Kawakami H, Uchihara JN, Okudaira T, Masuda M, Takasu N, Matsuda T, Ohta T, Tanaka Y, Ohshiro K, Mori N.


Curcumin (diferuloylmethane) inhibits constitutive active NF-kappaB, leading to suppression of cell growth of human T-cell leukemia virus type I-infected T-cell lines and primary adult T-cell leukemia cells.Int J Cancer. 2006 Feb 1;118(3):765-72. PMID: 16106398 [PubMed - indexed for MEDLINE]

131: Woo MS, Jung SH, Kim SY, Hyun JW, Ko KH, Kim WK, Kim HS. Related Articles, Links Curcumin suppresses phorbol ester-induced matrix metalloproteinase-9 expression by inhibiting the PKC to MAPK signaling pathways in human astroglioma cells.Biochem Biophys Res Commun. 2005 Oct 7;335(4):1017-25. PMID: 16102725 [PubMed - indexed for MEDLINE]

132: Ramachandran C, Rodriguez S, Ramachandran R, Raveendran Nair PK, Related Articles, Links





































Fonseca H, Khatib Z, Escalon E, Melnick SJ.Expression profiles of apoptotic genes induced by curcumin in human breast cancer and mammary epithelial cell lines.Anticancer Res. 2005 Sep-Oct;25(5):3293-302. PMID: 16101141 [PubMed - indexed for MEDLINE]

133: Li L, Braiteh FS, Kurzrock R. Related Articles, Links Liposome-encapsulated curcumin: in vitro and in vivo effects on proliferation, apoptosis, signaling, and angiogenesis.Cancer. 2005 Sep 15;104(6):1322-31. PMID: 16092118 [PubMed - indexed for MEDLINE]

134: Manson MM. Related Articles, Links Inhibition of survival signalling by dietary polyphenols and indole-3-carbinol.Eur J Cancer. 2005 Sep;41(13):1842-53. PMID: 16087329 [PubMed - indexed for MEDLINE]

135: Kwon HJ, Kakeya H. Related Articles, Links [Chemical genomics on new angiogenesis inhibitors]Tanpakushitsu Kakusan Koso. 2005 Aug;50(9):1056-62. Review. Japanese. No abstract available. PMID: 16083043 [PubMed - indexed for MEDLINE]

136: Sharma RA, Gescher AJ, Steward WP. Related Articles, Links Curcumin: the story so far.Eur J Cancer. 2005 Sep;41(13):1955-68. Review. PMID: 16081279 [PubMed - indexed for MEDLINE]

137: Jurrmann N, Brigelius-Flohe R, Bol GF. Related Articles, Links Curcumin blocks interleukin-1 (IL-1) signaling by inhibiting the recruitment of the IL-1 receptor-associated kinase IRAK in murine thymoma EL-4 cells.J Nutr. 2005 Aug;135(8):1859-64. PMID: 16046709 [PubMed - indexed for MEDLINE]

138: Venkatraman M, Anto RJ, Nair A, Varghese M, Karunagaran D. Related Articles, Links Biological and chemical inhibitors of NF-kappaB sensitize SiHa cells to cisplatin-induced apoptosis.Mol Carcinog. 2005 Sep;44(1):51-9. PMID: 16044419 [PubMed - indexed for MEDLINE]

139: Uddin S, Hussain AR, Manogaran PS, Al-Hussein K, Platanias LC, Gutierrez MI, Bhatia KG.


Curcumin suppresses growth and induces apoptosis in primary effusion lymphoma.Oncogene. 2005 Oct 27;24(47):7022-30. PMID: 16044161 [PubMed - indexed for MEDLINE]

140: Tang XQ, Bi H, Feng JQ, Cao JG. Related Articles, Links Effect of curcumin on multidrug resistance in resistant human gastric carcinoma cell line SGC7901/VCR.Acta Pharmacol Sin. 2005 Aug;26(8):1009-16. PMID: 16038636 [PubMed - indexed for MEDLINE]

Items 121 - 140 of 599

141: Kim HT, Qiang W, Liu N, Scofield VL, Wong PK, Stoica G. Related Articles, Links Up-regulation of astrocyte cyclooxygenase-2, CCAAT/enhancer-binding protein-homology protein, glucose-related protein 78, eukaryotic initiation factor 2 alpha, and c-Jun N-terminal kinase by a neurovirulent murine retrovirus.J Neurovirol. 2005 Apr;11(2):166-79. PMID: 16036795 [PubMed - indexed for MEDLINE]

142: Shishodia S, Amin HM, Lai R, Aggarwal BB. Related Articles, Links Curcumin (diferuloylmethane) inhibits constitutive NF-kappaB activation, induces G1/S arrest, suppresses proliferation, and induces apoptosis in mantle cell lymphoma.Biochem Pharmacol. 2005 Sep 1;70(5):700-13. PMID: 16023083 [PubMed - indexed for MEDLINE]

143: Chearwae W, Wu CP, Chu HY, Lee TR, Ambudkar SV, Limtrakul P. Related Articles, Links




































Curcuminoids purified from turmeric powder modulate the function of human multidrug resistance protein 1 (ABCC1).Cancer Chemother Pharmacol. 2006 Feb;57(3):376-88. Epub 2005 Jul 14. PMID: 16021489 [PubMed - indexed for MEDLINE]

144: Belakavadi M, Salimath BP. Related Articles, Links Mechanism of inhibition of ascites tumor growth in mice by curcumin is mediated by NF-kB and caspase activated DNase.Mol Cell Biochem. 2005 May;273(1-2):57-67. PMID: 16013440 [PubMed - indexed for MEDLINE]

145: Sreepriya M, Bali G. Related Articles, Links Chemopreventive effects of embelin and curcumin against N-nitrosodiethylamine/phenobarbital-induced hepatocarcinogenesis in Wistar rats.Fitoterapia. 2005 Sep;76(6):549-55. PMID: 16009505 [PubMed - indexed for MEDLINE]

146: Siwak DR, Shishodia S, Aggarwal BB, Kurzrock R. Related Articles, Links Curcumin-induced antiproliferative and proapoptotic effects in melanoma cells are associated with suppression of IkappaB kinase and nuclear factor kappaB activity and are independent of the B-Raf/mitogen-activated/extracellular signal-regulated protein kinase pathway and the Akt pathway.Cancer. 2005 Aug 15;104(4):879-90. PMID: 16007726 [PubMed - indexed for MEDLINE]

147: Lee J, Im YH, Jung HH, Kim JH, Park JO, Kim K, Kim WS, Ahn JS, Jung CW, Park YS, Kang WK, Park K.


Curcumin inhibits interferon-alpha induced NF-kappaB and COX-2 in human A549 non-small cell lung cancer cells.Biochem Biophys Res Commun. 2005 Aug 26;334(2):313-8. PMID: 16005433 [PubMed - indexed for MEDLINE]

148: Depeille P, Cuq P, Passagne I, Evrard A, Vian L. Related Articles, Links Combined effects of GSTP1 and MRP1 in melanoma drug resistance.Br J Cancer. 2005 Jul 25;93(2):216-23. PMID: 15999103 [PubMed - indexed for MEDLINE]

149: Shimizu M, Weinstein IB. Related Articles, Links Modulation of signal transduction by tea catechins and related phytochemicals.Mutat Res. 2005 Dec 11;591(1-2):147-60. Epub 2005 Jun 29. Review. PMID: 15992833 [PubMed - indexed for MEDLINE]

150: Jung EM, Lim JH, Lee TJ, Park JW, Choi KS, Kwon TK. Related Articles, Links Curcumin sensitizes tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis through reactive oxygen species-mediated upregulation of death receptor 5 (DR5).Carcinogenesis. 2005 Nov;26(11):1905-13. Epub 2005 Jun 29. PMID: 15987718 [PubMed - indexed for MEDLINE]

151: Atsumi T, Fujisawa S, Tonosaki K. Related Articles, Links Relationship between intracellular ROS production and membrane mobility in curcumin- and tetrahydrocurcumin-treated human gingival fibroblasts and human submandibular gland carcinoma cells.Oral Dis. 2005 Jul;11(4):236-42. PMID: 15984955 [PubMed - indexed for MEDLINE]

152: Chan WH, Wu HJ, Hsuuw YD. Related Articles, Links Curcumin inhibits ROS formation and apoptosis in methylglyoxal-treated human hepatoma G2 cells.Ann N Y Acad Sci. 2005 May;1042:372-8. PMID: 15965083 [PubMed - indexed for MEDLINE]

153: Collado B, Sanchez MG, Diaz-Laviada I, Prieto JC, Carmena MJ. Related Articles, Links Vasoactive intestinal peptide (VIP) induces c-fos expression in LNCaP prostate cancer cells through a mechanism that involves Ca2+ signalling. Implications in

































angiogenesis and neuroendocrine differentiation.Biochim Biophys Acta. 2005 Jun 30;1744(2):224-33. PMID: 15921770 [PubMed - indexed for MEDLINE]

154: [No authors listed] Related Articles, Links New developments in the realm of complementary medicine.J Support Oncol. 2005 May-Jun;3(3):238-40, 245-6. No abstract available. PMID: 15915827 [PubMed - indexed for MEDLINE]

155: Bharti AC, Takada Y, Aggarwal BB. Related Articles, Links PARP cleavage and caspase activity to assess chemosensitivity.Methods Mol Med. 2005;111:69-78. PMID: 15911972 [PubMed - indexed for MEDLINE]

156: Robinson TP, Hubbard RB 4th, Ehlers TJ, Arbiser JL, Goldsmith DJ, Bowen JP.


Synthesis and biological evaluation of aromatic enones related to curcumin.Bioorg Med Chem. 2005 Jun 2;13(12):4007-13. PMID: 15911313 [PubMed - indexed for MEDLINE]

157: Notarbartolo M, Poma P, Perri D, Dusonchet L, Cervello M, D'Alessandro N.


Antitumor effects of curcumin, alone or in combination with cisplatin or doxorubicin, on human hepatic cancer cells. Analysis of their possible relationship to changes in NF-kB activation levels and in IAP gene expression.Cancer Lett. 2005 Jun 16;224(1):53-65. PMID: 15911101 [PubMed - indexed for MEDLINE]

158: Duvoix A, Blasius R, Delhalle S, Schnekenburger M, Morceau F, Henry E, Dicato M, Diederich M.


Chemopreventive and therapeutic effects of curcumin.Cancer Lett. 2005 Jun 8;223(2):181-90. Epub 2004 Nov 11. Review. PMID: 15896452 [PubMed - indexed for MEDLINE]

159: Park CH, Hahm ER, Park S, Kim HK, Yang CH. Related Articles, Links The inhibitory mechanism of curcumin and its derivative against beta-catenin/Tcf signaling.FEBS Lett. 2005 May 23;579(13):2965-71. Epub 2005 Apr 21. PMID: 15893313 [PubMed - indexed for MEDLINE]

160: Sen S, Sharma H, Singh N. Related Articles, Links Curcumin enhances Vinorelbine mediated apoptosis in NSCLC cells by the mitochondrial pathway.Biochem Biophys Res Commun. 2005 Jun 17;331(4):1245-52. PMID: 15883009 [PubMed - indexed for MEDLINE]

Items 141 - 160 of 599161: Fang J, Lu J, Holmgren A. Related Articles, Links

Thioredoxin reductase is irreversibly modified by curcumin: a novel molecular mechanism for its anticancer activity.J Biol Chem. 2005 Jul 1;280(26):25284-90. Epub 2005 May 6. PMID: 15879598 [PubMed - indexed for MEDLINE]

162: Lesniak W, Szczepanska A, Kuznicki J. Related Articles, Links Calcyclin (S100A6) expression is stimulated by agents evoking oxidative stress via the antioxidant response element.Biochim Biophys Acta. 2005 May 15;1744(1):29-37. Epub 2004 Nov 26. PMID: 15878395 [PubMed - indexed for MEDLINE]

163: Dutta S, Padhye S, Priyadarsini KI, Newton C. Related Articles, Links Antioxidant and antiproliferative activity of curcumin semicarbazone.Bioorg Med Chem Lett. 2005 Jun 2;15(11):2738-44. PMID: 15878268 [PubMed - indexed for MEDLINE]

164: Weber WM, Hunsaker LA, Abcouwer SF, Deck LM, Vander Jagt DL. Related Articles, Links Anti-oxidant activities of curcumin and related enones.Bioorg Med Chem. 2005 Jun 1;13(11):3811-20.





































PMID: 15863007 [PubMed - indexed for MEDLINE]165: Mishra S, Kapoor N, Mubarak Ali A, Pardhasaradhi BV, Kumari AL, Khar

A, Misra K.Related Articles, Links

Differential apoptotic and redox regulatory activities of curcumin and its derivatives.Free Radic Biol Med. 2005 May 15;38(10):1353-60. PMID: 15855053 [PubMed - indexed for MEDLINE]

166: Kim KH, Park HY, Nam JH, Park JE, Kim JY, Park MI, Chung KO, Park KY, Koo JY.


[The inhibitory effect of curcumin on the growth of human colon cancer cells (HT-29, WiDr) in vitro]Korean J Gastroenterol. 2005 Apr;45(4):277-84. Korean. PMID: 15843753 [PubMed - indexed for MEDLINE]

167: Liu HL, Chen Y, Cui GH, Zhou JF. Related Articles, Links Curcumin, a potent anti-tumor reagent, is a novel histone deacetylase inhibitor regulating B-NHL cell line Raji proliferation.Acta Pharmacol Sin. 2005 May;26(5):603-9. PMID: 15842781 [PubMed - indexed for MEDLINE]

168: Ferguson LR, Zhu ST, Harris PJ. Related Articles, Links Antioxidant and antigenotoxic effects of plant cell wall hydroxycinnamic acids in cultured HT-29 cells.Mol Nutr Food Res. 2005 Jun;49(6):585-93. PMID: 15841493 [PubMed - indexed for MEDLINE]

169: Volate SR, Davenport DM, Muga SJ, Wargovich MJ. Related Articles, Links Modulation of aberrant crypt foci and apoptosis by dietary herbal supplements (quercetin, curcumin, silymarin, ginseng and rutin).Carcinogenesis. 2005 Aug;26(8):1450-6. Epub 2005 Apr 14. PMID: 15831530 [PubMed - indexed for MEDLINE]

170: Karunagaran D, Rashmi R, Kumar TR. Related Articles, Links Induction of apoptosis by curcumin and its implications for cancer therapy.Curr Cancer Drug Targets. 2005 Mar;5(2):117-29. Review. PMID: 15810876 [PubMed - indexed for MEDLINE]

171: Sun M, Yang Y, Li H, Su B, Lu Y, Wei Q, Fan T. Related Articles, Links [The effect of curcumin on bladder cancer cell line EJ in vitro]Zhong Yao Cai. 2004 Nov;27(11):848-50. Chinese. PMID: 15810596 [PubMed - indexed for MEDLINE]

172: Tsvetkov P, Asher G, Reiss V, Shaul Y, Sachs L, Lotem J. Related Articles, Links Inhibition of NAD(P)H:quinone oxidoreductase 1 activity and induction of p53 degradation by the natural phenolic compound curcumin.Proc Natl Acad Sci U S A. 2005 Apr 12;102(15):5535-40. Epub 2005 Apr 4. PMID: 15809436 [PubMed - indexed for MEDLINE]

173: Zhang J, Qi H, Wu C. Related Articles, Links [Research of anti-proliferation of curcumin on A549 human lung cancer cells and its mechanism]Zhong Yao Cai. 2004 Dec;27(12):923-7. Chinese. PMID: 15807244 [PubMed - indexed for MEDLINE]

174: Ray A. Related Articles, Links Cancer preventive role of selected dietary factors.Indian J Cancer. 2005 Jan-Mar;42(1):15-24. Review. PMID: 15805687 [PubMed - indexed for MEDLINE]

175: Dulak J. Related Articles, Links Nutraceuticals as anti-angiogenic agents: hopes and reality.J Physiol Pharmacol. 2005 Mar;56 Suppl 1:51-69. PMID: 15800385 [PubMed - in process]

176: Kang J, Chen J, Shi Y, Jia J, Zhang Y. Related Articles, Links Curcumin-induced histone hypoacetylation: the role of reactive oxygen species.Biochem Pharmacol. 2005 Apr 15;69(8):1205-13.







































PMID: 15794941 [PubMed - indexed for MEDLINE]177: Tripathi YB, Tripathi P, Arjmandi BH. Related Articles, Links

Nutraceuticals and cancer management.Front Biosci. 2005 May 1;10:1607-18. Review. PMID: 15769650 [PubMed - indexed for MEDLINE]

178: Bachmeier BE, Iancu CM, Jochum M, Nerlich AG. Related Articles, Links Matrix metalloproteinases in cancer: comparison of known and novel aspects of their inhibition as a therapeutic approach.Expert Rev Anticancer Ther. 2005 Feb;5(1):149-63. Review. PMID: 15757447 [PubMed - indexed for MEDLINE]

179: Song S, Byrd JC, Koo JS, Bresalier RS. Related Articles, Links Bile acids induce MUC2 overexpression in human colon carcinoma cells.Cancer. 2005 Apr 15;103(8):1606-14. PMID: 15754327 [PubMed - indexed for MEDLINE]

180: Choudhuri T, Pal S, Das T, Sa G. Related Articles, Links Curcumin selectively induces apoptosis in deregulated cyclin D1-expressed cells at G2 phase of cell cycle in a p53-dependent manner.J Biol Chem. 2005 May 20;280(20):20059-68. Epub 2005 Feb 28. PMID: 15738001 [PubMed - indexed for MEDLINE]Items 161 - 180 of 599

181: Huang CY, Chen JH, Tsai CH, Kuo WW, Liu JY, Chang YC.


Regulation of extracellular signal-regulated protein kinase signaling in human osteosarcoma cells stimulated with nicotine.J Periodontal Res. 2005 Apr;40(2):176-81. PMID: 15733153 [PubMed - indexed for MEDLINE]

182: Furness MS, Robinson TP, Ehlers T, Hubbard RB 4th, Arbiser JL, Goldsmith DJ, Bowen JP.


Antiangiogenic agents: studies on fumagillin and curcumin analogs.Curr Pharm Des. 2005;11(3):357-73. Review. PMID: 15723631 [PubMed - indexed for MEDLINE]

183: Yan C, Jamaluddin MS, Aggarwal B, Myers J, Boyd DD. Related Articles, Links Gene expression profiling identifies activating transcription factor 3 as a novel contributor to the proapoptotic effect of curcumin.Mol Cancer Ther. 2005 Feb;4(2):233-41. PMID: 15713895 [PubMed - indexed for MEDLINE]

184: Adams BK, Cai J, Armstrong J, Herold M, Lu YJ, Sun A, Snyder JP, Liotta DC, Jones DP, Shoji M.


EF24, a novel synthetic curcumin analog, induces apoptosis in cancer cells via a redox-dependent mechanism.Anticancer Drugs. 2005 Mar;16(3):263-75. PMID: 15711178 [PubMed - indexed for MEDLINE]

185: Chen J, Wanming D, Zhang D, Liu Q, Kang J. Related Articles, Links Water-soluble antioxidants improve the antioxidant and anticancer activity of low concentrations of curcumin in human leukemia cells.Pharmazie. 2005 Jan;60(1):57-61. PMID: 15700780 [PubMed - indexed for MEDLINE]

186: Khafif A, Hurst R, Kyker K, Fliss DM, Gil Z, Medina JE. Related Articles, Links Curcumin: a new radio-sensitizer of squamous cell carcinoma cells.Otolaryngol Head Neck Surg. 2005 Feb;132(2):317-21. PMID: 15692547 [PubMed - indexed for MEDLINE]

187: Gescher A. Related Articles, Links Polyphenolic phytochemicals versus non-steroidal anti-inflammatory drugs: which are better cancer chemopreventive agents?J Chemother. 2004 Nov;16 Suppl 4:3-6. Review.





































PMID: 15688599 [PubMed - indexed for MEDLINE]188: Garcea G, Berry DP, Jones DJ, Singh R, Dennison AR, Farmer PB,

Sharma RA, Steward WP, Gescher AJ.Related Articles, Links

Consumption of the putative chemopreventive agent curcumin by cancer patients: assessment of curcumin levels in the colorectum and their pharmacodynamic consequences.Cancer Epidemiol Biomarkers Prev. 2005 Jan;14(1):120-5. PMID: 15668484 [PubMed - indexed for MEDLINE]

189: Rashmi R, Kumar S, Karunagaran D. Related Articles, Links Human colon cancer cells lacking Bax resist curcumin-induced apoptosis and Bax requirement is dispensable with ectopic expression of Smac or downregulation of Bcl-XL.Carcinogenesis. 2005 Apr;26(4):713-23. Epub 2005 Jan 20. PMID: 15661804 [PubMed - indexed for MEDLINE]

190: Aggarwal BB, Shishodia S. Related Articles, Links Suppression of the nuclear factor-kappaB activation pathway by spice-derived phytochemicals: reasoning for seasoning.Ann N Y Acad Sci. 2004 Dec;1030:434-41. Review. PMID: 15659827 [PubMed - indexed for MEDLINE]

191: Manson MM, Farmer PB, Gescher A, Steward WP. Related Articles, Links Innovative agents in cancer prevention.Recent Results Cancer Res. 2005;166:257-75. Review. PMID: 15648195 [PubMed - indexed for MEDLINE]

192: Lambert JD, Hong J, Yang GY, Liao J, Yang CS. Related Articles, Links Inhibition of carcinogenesis by polyphenols: evidence from laboratory investigations.Am J Clin Nutr. 2005 Jan;81(1 Suppl):284S-291S. Review. PMID: 15640492 [PubMed - indexed for MEDLINE]

193: Kumar Mitra A, Krishna M. Related Articles, Links In vivo modulation of signaling factors involved in cell survival.J Radiat Res (Tokyo). 2004 Dec;45(4):491-5. PMID: 15635257 [PubMed - indexed for MEDLINE]

194: Nishino H, Tokuda H, Satomi Y, Masuda M, Osaka Y, Yogosawa S, Wada S, Mou XY, Takayasu J, Murakoshi M, Jinnno K, Yano M.


Cancer prevention by antioxidants.Biofactors. 2004;22(1-4):57-61. PMID: 15630252 [PubMed - indexed for MEDLINE]

195: Sun CY, Liu XY, Chen Y, Liu F, Wang Y. Related Articles, Links [Experimental study on anticancer effect of curcumin on Raji cells in vitro]Zhongguo Zhong Xi Yi Jie He Za Zhi. 2004 Nov;24(11):1003-6. Chinese. PMID: 15609600 [PubMed - indexed for MEDLINE]

196: Liang T, Chen MJ, Zhou KY, Tang XD, Wang XG. Related Articles, Links [Induction of apoptosis in human nasopharyngeal carcinoma cell line CNE-2Z by curcumin.]Ai Zheng. 2004 Dec;23(12):1651-4. Chinese. PMID: 15601554 [PubMed - indexed for MEDLINE]

197: Choi SM, Lee BM. Related Articles, Links An alternative mode of action of endocrine-disrupting chemicals and chemoprevention.J Toxicol Environ Health B Crit Rev. 2004 Nov-Dec;7(6):451-63. Review. PMID: 15586879 [PubMed - indexed for MEDLINE]

198: Shim JS, Kwon HJ. Related Articles, Links Chemical genetics for therapeutic target mining.Expert Opin Ther Targets. 2004 Dec;8(6):653-61. Review. PMID: 15584869 [PubMed - indexed for MEDLINE]

199: Ferrari CK. Related Articles, Links






































Functional foods, herbs and nutraceuticals: towards biochemical mechanisms of healthy aging.Biogerontology. 2004;5(5):275-89. Review. PMID: 15547316 [PubMed - indexed for MEDLINE]

200: Thompson KH, Bohmerle K, Polishchuk E, Martins C, Toleikis P, Tse J, Yuen V, McNeill JH, Orvig C.


Complementary inhibition of synoviocyte, smooth muscle cell or mouse lymphoma cell proliferation by a vanadyl curcumin complex compared to curcumin alone.J Inorg Biochem. 2004 Dec;98(12):2063-70. PMID: 15541495 [PubMed - indexed for MEDLINE]

201: Atsumi T, Fujisawa S, Tonosaki K. Related Articles, Links Relationship between intracellular ROS production and membrane mobility in curcumin- and tetrahydrocurcumin-treated human gingival fibroblasts and human submandibular gland carcinoma cells.Oral Dis. 2005 Jul;11(4):236-42. PMID: 15984955 [PubMed - indexed for MEDLINE]

202: Chan WH, Wu HJ, Hsuuw YD. Related Articles, Links Curcumin inhibits ROS formation and apoptosis in methylglyoxal-treated human hepatoma G2 cells.Ann N Y Acad Sci. 2005 May;1042:372-8. PMID: 15965083 [PubMed - indexed for MEDLINE]

203: Collado B, Sanchez MG, Diaz-Laviada I, Prieto JC, Carmena MJ. Related Articles, Links Vasoactive intestinal peptide (VIP) induces c-fos expression in LNCaP prostate cancer cells through a mechanism that involves Ca2+ signalling. Implications in angiogenesis and neuroendocrine differentiation.Biochim Biophys Acta. 2005 Jun 30;1744(2):224-33. PMID: 15921770 [PubMed - indexed for MEDLINE]

204: [No authors listed] Related Articles, Links New developments in the realm of complementary medicine.J Support Oncol. 2005 May-Jun;3(3):238-40, 245-6. No abstract available. PMID: 15915827 [PubMed - indexed for MEDLINE]

205: Bharti AC, Takada Y, Aggarwal BB. Related Articles, Links PARP cleavage and caspase activity to assess chemosensitivity.Methods Mol Med. 2005;111:69-78. PMID: 15911972 [PubMed - indexed for MEDLINE]

206: Robinson TP, Hubbard RB 4th, Ehlers TJ, Arbiser JL, Goldsmith DJ, Bowen JP.


Synthesis and biological evaluation of aromatic enones related to curcumin.Bioorg Med Chem. 2005 Jun 2;13(12):4007-13. PMID: 15911313 [PubMed - indexed for MEDLINE]

207: Notarbartolo M, Poma P, Perri D, Dusonchet L, Cervello M, D'Alessandro N.


Antitumor effects of curcumin, alone or in combination with cisplatin or doxorubicin, on human hepatic cancer cells. Analysis of their possible relationship to changes in NF-kB activation levels and in IAP gene expression.Cancer Lett. 2005 Jun 16;224(1):53-65. PMID: 15911101 [PubMed - indexed for MEDLINE]

208: Duvoix A, Blasius R, Delhalle S, Schnekenburger M, Morceau F, Henry E, Dicato M, Diederich M.


Chemopreventive and therapeutic effects of curcumin.Cancer Lett. 2005 Jun 8;223(2):181-90. Epub 2004 Nov 11. Review. PMID: 15896452 [PubMed - indexed for MEDLINE]

209: Park CH, Hahm ER, Park S, Kim HK, Yang CH. Related Articles, Links The inhibitory mechanism of curcumin and its derivative against beta-catenin/Tcf signaling.




































FEBS Lett. 2005 May 23;579(13):2965-71. Epub 2005 Apr 21. PMID: 15893313 [PubMed - indexed for MEDLINE]

210: Sen S, Sharma H, Singh N. Related Articles, Links Curcumin enhances Vinorelbine mediated apoptosis in NSCLC cells by the mitochondrial pathway.Biochem Biophys Res Commun. 2005 Jun 17;331(4):1245-52. PMID: 15883009 [PubMed - indexed for MEDLINE]

211: Fang J, Lu J, Holmgren A. Related Articles, Links Thioredoxin reductase is irreversibly modified by curcumin: a novel molecular mechanism for its anticancer activity.J Biol Chem. 2005 Jul 1;280(26):25284-90. Epub 2005 May 6. PMID: 15879598 [PubMed - indexed for MEDLINE]

212: Lesniak W, Szczepanska A, Kuznicki J. Related Articles, Links Calcyclin (S100A6) expression is stimulated by agents evoking oxidative stress via the antioxidant response element.Biochim Biophys Acta. 2005 May 15;1744(1):29-37. Epub 2004 Nov 26. PMID: 15878395 [PubMed - indexed for MEDLINE]

213: Dutta S, Padhye S, Priyadarsini KI, Newton C. Related Articles, Links Antioxidant and antiproliferative activity of curcumin semicarbazone.Bioorg Med Chem Lett. 2005 Jun 2;15(11):2738-44. PMID: 15878268 [PubMed - indexed for MEDLINE]

214: Weber WM, Hunsaker LA, Abcouwer SF, Deck LM, Vander Jagt DL. Related Articles, Links Anti-oxidant activities of curcumin and related enones.Bioorg Med Chem. 2005 Jun 1;13(11):3811-20. PMID: 15863007 [PubMed - indexed for MEDLINE]

215: Mishra S, Kapoor N, Mubarak Ali A, Pardhasaradhi BV, Kumari AL, Khar A, Misra K.


Differential apoptotic and redox regulatory activities of curcumin and its derivatives.Free Radic Biol Med. 2005 May 15;38(10):1353-60. PMID: 15855053 [PubMed - indexed for MEDLINE]

216: Kim KH, Park HY, Nam JH, Park JE, Kim JY, Park MI, Chung KO, Park KY, Koo JY.


[The inhibitory effect of curcumin on the growth of human colon cancer cells (HT-29, WiDr) in vitro]Korean J Gastroenterol. 2005 Apr;45(4):277-84. Korean. PMID: 15843753 [PubMed - indexed for MEDLINE]

217: Liu HL, Chen Y, Cui GH, Zhou JF. Related Articles, Links Curcumin, a potent anti-tumor reagent, is a novel histone deacetylase inhibitor regulating B-NHL cell line Raji proliferation.Acta Pharmacol Sin. 2005 May;26(5):603-9. PMID: 15842781 [PubMed - indexed for MEDLINE]

218: Ferguson LR, Zhu ST, Harris PJ. Related Articles, Links Antioxidant and antigenotoxic effects of plant cell wall hydroxycinnamic acids in cultured HT-29 cells.Mol Nutr Food Res. 2005 Jun;49(6):585-93. PMID: 15841493 [PubMed - indexed for MEDLINE]

219: Volate SR, Davenport DM, Muga SJ, Wargovich MJ. Related Articles, Links Modulation of aberrant crypt foci and apoptosis by dietary herbal supplements (quercetin, curcumin, silymarin, ginseng and rutin).Carcinogenesis. 2005 Aug;26(8):1450-6. Epub 2005 Apr 14. PMID: 15831530 [PubMed - indexed for MEDLINE]

220: Karunagaran D, Rashmi R, Kumar TR. Related Articles, Links Induction of apoptosis by curcumin and its implications for cancer therapy.Curr Cancer Drug Targets. 2005 Mar;5(2):117-29. Review. PMID: 15810876 [PubMed - indexed for MEDLINE]

Items 201 - 220 of 649




































221: Sun M, Yang Y, Li H, Su B, Lu Y, Wei Q, Fan T. Related Articles, Links [The effect of curcumin on bladder cancer cell line EJ in vitro]Zhong Yao Cai. 2004 Nov;27(11):848-50. Chinese. PMID: 15810596 [PubMed - indexed for MEDLINE]

222: Tsvetkov P, Asher G, Reiss V, Shaul Y, Sachs L, Lotem J. Related Articles, Links Inhibition of NAD(P)H:quinone oxidoreductase 1 activity and induction of p53 degradation by the natural phenolic compound curcumin.Proc Natl Acad Sci U S A. 2005 Apr 12;102(15):5535-40. Epub 2005 Apr 4. PMID: 15809436 [PubMed - indexed for MEDLINE]

223: Zhang J, Qi H, Wu C. Related Articles, Links [Research of anti-proliferation of curcumin on A549 human lung cancer cells and its mechanism]Zhong Yao Cai. 2004 Dec;27(12):923-7. Chinese. PMID: 15807244 [PubMed - indexed for MEDLINE]

224: Ray A. Related Articles, Links Cancer preventive role of selected dietary factors.Indian J Cancer. 2005 Jan-Mar;42(1):15-24. Review. PMID: 15805687 [PubMed - indexed for MEDLINE]

225: Dulak J. Related Articles, Links Nutraceuticals as anti-angiogenic agents: hopes and reality.J Physiol Pharmacol. 2005 Mar;56 Suppl 1:51-69. PMID: 15800385 [PubMed - in process]

226: Kang J, Chen J, Shi Y, Jia J, Zhang Y. Related Articles, Links Curcumin-induced histone hypoacetylation: the role of reactive oxygen species.Biochem Pharmacol. 2005 Apr 15;69(8):1205-13. PMID: 15794941 [PubMed - indexed for MEDLINE]

227: Tripathi YB, Tripathi P, Arjmandi BH. Related Articles, Links Nutraceuticals and cancer management.Front Biosci. 2005 May 1;10:1607-18. Review. PMID: 15769650 [PubMed - indexed for MEDLINE]

228: Bachmeier BE, Iancu CM, Jochum M, Nerlich AG. Related Articles, Links Matrix metalloproteinases in cancer: comparison of known and novel aspects of their inhibition as a therapeutic approach.Expert Rev Anticancer Ther. 2005 Feb;5(1):149-63. Review. PMID: 15757447 [PubMed - indexed for MEDLINE]

229: Song S, Byrd JC, Koo JS, Bresalier RS. Related Articles, Links Bile acids induce MUC2 overexpression in human colon carcinoma cells.Cancer. 2005 Apr 15;103(8):1606-14. PMID: 15754327 [PubMed - indexed for MEDLINE]

230: Choudhuri T, Pal S, Das T, Sa G. Related Articles, Links Curcumin selectively induces apoptosis in deregulated cyclin D1-expressed cells at G2 phase of cell cycle in a p53-dependent manner.J Biol Chem. 2005 May 20;280(20):20059-68. Epub 2005 Feb 28. PMID: 15738001 [PubMed - indexed for MEDLINE]

231: Huang CY, Chen JH, Tsai CH, Kuo WW, Liu JY, Chang YC. Related Articles, Links Regulation of extracellular signal-regulated protein kinase signaling in human osteosarcoma cells stimulated with nicotine.J Periodontal Res. 2005 Apr;40(2):176-81. PMID: 15733153 [PubMed - indexed for MEDLINE]

232: Furness MS, Robinson TP, Ehlers T, Hubbard RB 4th, Arbiser JL, Goldsmith DJ, Bowen JP.


Antiangiogenic agents: studies on fumagillin and curcumin analogs.Curr Pharm Des. 2005;11(3):357-73. Review. PMID: 15723631 [PubMed - indexed for MEDLINE]

233: Yan C, Jamaluddin MS, Aggarwal B, Myers J, Boyd DD. Related Articles, Links








































Gene expression profiling identifies activating transcription factor 3 as a novel contributor to the proapoptotic effect of curcumin.Mol Cancer Ther. 2005 Feb;4(2):233-41. PMID: 15713895 [PubMed - indexed for MEDLINE]

234: Adams BK, Cai J, Armstrong J, Herold M, Lu YJ, Sun A, Snyder JP, Liotta DC, Jones DP, Shoji M.


EF24, a novel synthetic curcumin analog, induces apoptosis in cancer cells via a redox-dependent mechanism.Anticancer Drugs. 2005 Mar;16(3):263-75. PMID: 15711178 [PubMed - indexed for MEDLINE]

235: Chen J, Wanming D, Zhang D, Liu Q, Kang J. Related Articles, Links Water-soluble antioxidants improve the antioxidant and anticancer activity of low concentrations of curcumin in human leukemia cells.Pharmazie. 2005 Jan;60(1):57-61. PMID: 15700780 [PubMed - indexed for MEDLINE]

236: Khafif A, Hurst R, Kyker K, Fliss DM, Gil Z, Medina JE. Related Articles, Links Curcumin: a new radio-sensitizer of squamous cell carcinoma cells.Otolaryngol Head Neck Surg. 2005 Feb;132(2):317-21. PMID: 15692547 [PubMed - indexed for MEDLINE]

237: Gescher A. Related Articles, Links Polyphenolic phytochemicals versus non-steroidal anti-inflammatory drugs: which are better cancer chemopreventive agents?J Chemother. 2004 Nov;16 Suppl 4:3-6. Review. PMID: 15688599 [PubMed - indexed for MEDLINE]

238: Garcea G, Berry DP, Jones DJ, Singh R, Dennison AR, Farmer PB, Sharma RA, Steward WP, Gescher AJ.


Consumption of the putative chemopreventive agent curcumin by cancer patients: assessment of curcumin levels in the colorectum and their pharmacodynamic consequences.Cancer Epidemiol Biomarkers Prev. 2005 Jan;14(1):120-5. PMID: 15668484 [PubMed - indexed for MEDLINE]

239: Rashmi R, Kumar S, Karunagaran D. Related Articles, Links Human colon cancer cells lacking Bax resist curcumin-induced apoptosis and Bax requirement is dispensable with ectopic expression of Smac or downregulation of Bcl-XL.Carcinogenesis. 2005 Apr;26(4):713-23. Epub 2005 Jan 20. PMID: 15661804 [PubMed - indexed for MEDLINE]

240: Aggarwal BB, Shishodia S. Related Articles, Links Suppression of the nuclear factor-kappaB activation pathway by spice-derived phytochemicals: reasoning for seasoning.Ann N Y Acad Sci. 2004 Dec;1030:434-41. Review. PMID: 15659827 [PubMed - indexed for MEDLINE]

241: Manson MM, Farmer PB, Gescher A, Steward WP. Related Articles, Links Innovative agents in cancer prevention.Recent Results Cancer Res. 2005;166:257-75. Review. PMID: 15648195 [PubMed - indexed for MEDLINE]

242: Lambert JD, Hong J, Yang GY, Liao J, Yang CS. Related Articles, Links Inhibition of carcinogenesis by polyphenols: evidence from laboratory investigations.Am J Clin Nutr. 2005 Jan;81(1 Suppl):284S-291S. Review. PMID: 15640492 [PubMed - indexed for MEDLINE]

243: Kumar Mitra A, Krishna M. Related Articles, Links In vivo modulation of signaling factors involved in cell survival.J Radiat Res (Tokyo). 2004 Dec;45(4):491-5. PMID: 15635257 [PubMed - indexed for MEDLINE]

244: Nishino H, Tokuda H, Satomi Y, Masuda M, Osaka Y, Yogosawa S, Wada Related Articles, Links




































S, Mou XY, Takayasu J, Murakoshi M, Jinnno K, Yano M.Cancer prevention by antioxidants.Biofactors. 2004;22(1-4):57-61. PMID: 15630252 [PubMed - indexed for MEDLINE]

245: Sun CY, Liu XY, Chen Y, Liu F, Wang Y. Related Articles, Links [Experimental study on anticancer effect of curcumin on Raji cells in vitro]Zhongguo Zhong Xi Yi Jie He Za Zhi. 2004 Nov;24(11):1003-6. Chinese. PMID: 15609600 [PubMed - indexed for MEDLINE]

246: Liang T, Chen MJ, Zhou KY, Tang XD, Wang XG. Related Articles, Links [Induction of apoptosis in human nasopharyngeal carcinoma cell line CNE-2Z by curcumin.]Ai Zheng. 2004 Dec;23(12):1651-4. Chinese. PMID: 15601554 [PubMed - indexed for MEDLINE]

247: Choi SM, Lee BM. Related Articles, Links An alternative mode of action of endocrine-disrupting chemicals and chemoprevention.J Toxicol Environ Health B Crit Rev. 2004 Nov-Dec;7(6):451-63. Review. PMID: 15586879 [PubMed - indexed for MEDLINE]

248: Shim JS, Kwon HJ. Related Articles, Links Chemical genetics for therapeutic target mining.Expert Opin Ther Targets. 2004 Dec;8(6):653-61. Review. PMID: 15584869 [PubMed - indexed for MEDLINE]

249: Ferrari CK. Related Articles, Links Functional foods, herbs and nutraceuticals: towards biochemical mechanisms of healthy aging.Biogerontology. 2004;5(5):275-89. Review. PMID: 15547316 [PubMed - indexed for MEDLINE]

250: Thompson KH, Bohmerle K, Polishchuk E, Martins C, Toleikis P, Tse J, Yuen V, McNeill JH, Orvig C.


Complementary inhibition of synoviocyte, smooth muscle cell or mouse lymphoma cell proliferation by a vanadyl curcumin complex compared to curcumin alone.J Inorg Biochem. 2004 Dec;98(12):2063-70. PMID: 15541495 [PubMed - indexed for MEDLINE]

251: Hong KO, Hwang JK, Park KK, Kim SH. Related Articles, Links Phosphorylation of c-Jun N-terminal Kinases (JNKs) is involved in the preventive effect of xanthorrhizol on cisplatin-induced hepatotoxicity.Arch Toxicol. 2005 Apr;79(4):231-6. Epub 2004 Nov 9. PMID: 15536542 [PubMed - indexed for MEDLINE]

252: Prusty BK, Das BC. Related Articles, Links Constitutive activation of transcription factor AP-1 in cervical cancer and suppression of human papillomavirus (HPV) transcription and AP-1 activity in HeLa cells by curcumin.Int J Cancer. 2005 Mar 1;113(6):951-60. PMID: 15514944 [PubMed - indexed for MEDLINE]

253: Sharma RA, Euden SA, Platton SL, Cooke DN, Shafayat A, Hewitt HR, Marczylo TH, Morgan B, Hemingway D, Plummer SM, Pirmohamed M, Gescher AJ, Steward WP.


Phase I clinical trial of oral curcumin: biomarkers of systemic activity and compliance.Clin Cancer Res. 2004 Oct 15;10(20):6847-54. PMID: 15501961 [PubMed - indexed for MEDLINE]

254: Gafner S, Lee SK, Cuendet M, Barthelemy S, Vergnes L, Labidalle S, Mehta RG, Boone CW, Pezzuto JM.


Biologic evaluation of curcumin and structural derivatives in cancer chemoprevention model systems.Phytochemistry. 2004 Nov;65(21):2849-59.





































PMID: 15501252 [PubMed - indexed for MEDLINE]255: Chen WH, Chen Y, Cui GH, Gu JX, Hu D, Chen WK, Li XG. Related Articles, Links

[Effect of curcumin on STAT5 signaling pathway in primary CML cells.]Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2004 Oct;12(5):572-6. Chinese. PMID: 15498113 [PubMed - indexed for MEDLINE]

256: Shenouda NS, Zhou C, Browning JD, Ansell PJ, Sakla MS, Lubahn DB, Macdonald RS.


Phytoestrogens in common herbs regulate prostate cancer cell growth in vitro.Nutr Cancer. 2004;49(2):200-8. PMID: 15489213 [PubMed - indexed for MEDLINE]

257: Shim JS, Lee J, Park HJ, Park SJ, Kwon HJ. Related Articles, Links A new curcumin derivative, HBC, interferes with the cell cycle progression of colon cancer cells via antagonization of the Ca2+/calmodulin function.Chem Biol. 2004 Oct;11(10):1455-63. PMID: 15489172 [PubMed - indexed for MEDLINE]

258: Dorai T, Aggarwal BB. Related Articles, Links Role of chemopreventive agents in cancer therapy.Cancer Lett. 2004 Nov 25;215(2):129-40. Review. PMID: 15488631 [PubMed - indexed for MEDLINE]

259: Chen A, Xu J. Related Articles, Links Activation of PPAR{gamma} by curcumin inhibits Moser cell growth and mediates suppression of gene expression of cyclin D1 and EGFR.Am J Physiol Gastrointest Liver Physiol. 2005 Mar;288(3):G447-56. Epub 2004 Oct 14. PMID: 15486348 [PubMed - indexed for MEDLINE]

260: Zsila F, Bikadi Z, Simonyi M. Related Articles, Links Circular dichroism spectroscopic studies reveal pH dependent binding of curcumin in the minor groove of natural and synthetic nucleic acids.Org Biomol Chem. 2004 Oct 21;2(20):2902-10. Epub 2004 Sep 23. PMID: 15480453 [PubMed - indexed for MEDLINE]

261: Liu CA, Wang MJ, Chi CW, Wu CW, Chen JY. Related Articles, Links Rho/Rhotekin-mediated NF-kappaB activation confers resistance to apoptosis.Oncogene. 2004 Nov 18;23(54):8731-42. PMID: 15480428 [PubMed - indexed for MEDLINE]

262: Wyke SM, Russell ST, Tisdale MJ. Related Articles, Links Induction of proteasome expression in skeletal muscle is attenuated by inhibitors of NF-kappaB activation.Br J Cancer. 2004 Nov 1;91(9):1742-50. PMID: 15477867 [PubMed - indexed for MEDLINE]

263: Sarkar FH, Li Y. Related Articles, Links Cell signaling pathways altered by natural chemopreventive agents.Mutat Res. 2004 Nov 2;555(1-2):53-64. Review. PMID: 15476851 [PubMed - indexed for MEDLINE]

264: Chearwae W, Anuchapreeda S, Nandigama K, Ambudkar SV, Limtrakul P. Related Articles, Links Biochemical mechanism of modulation of human P-glycoprotein (ABCB1) by curcumin I, II, and III purified from Turmeric powder.Biochem Pharmacol. 2004 Nov 15;68(10):2043-52. PMID: 15476675 [PubMed - indexed for MEDLINE]

265: Li L, Aggarwal BB, Shishodia S, Abbruzzese J, Kurzrock R. Related Articles, Links Nuclear factor-kappaB and IkappaB kinase are constitutively active in human pancreatic cells, and their down-regulation by curcumin (diferuloylmethane) is associated with the suppression of proliferation and the induction of apoptosis.Cancer. 2004 Nov 15;101(10):2351-62. PMID: 15476283 [PubMed - indexed for MEDLINE]

266: Sanchez-Beato M, Sanchez E, Garcia JF, Perez-Rosado A, Montoya MC, Fraga M, Artiga MJ, Navarrete M, Abraira V, Morente M, Esteller M,







































Koseki H, Vidal M, Piris MA.Abnormal PcG protein expression in Hodgkin's lymphoma. Relation with E2F6 and NFkappaB transcription factors.J Pathol. 2004 Dec;204(5):528-37. PMID: 15470680 [PubMed - indexed for MEDLINE]

267: Aggarwal BB, Takada Y, Oommen OV. Related Articles, Links From chemoprevention to chemotherapy: common targets and common goals.Expert Opin Investig Drugs. 2004 Oct;13(10):1327-38. Review. PMID: 15461561 [PubMed - indexed for MEDLINE]

268: Kellner C, Zunino SJ. Related Articles, Links Nitric oxide is synthesized in acute leukemia cells after exposure to phenolic antioxidants and initially protects against mitochondrial membrane depolarization.Cancer Lett. 2004 Nov 8;215(1):43-52. PMID: 15374631 [PubMed - indexed for MEDLINE]

269: Teijido O, Martinez A, Pusch M, Zorzano A, Soriano E, Del Rio JA, Palacin M, Estevez R.


Localization and functional analyses of the MLC1 protein involved in megalencephalic leukoencephalopathy with subcortical cysts.Hum Mol Genet. 2004 Nov 1;13(21):2581-94. Epub 2004 Sep 14. PMID: 15367490 [PubMed - indexed for MEDLINE]

270: Hahm ER, Gho YS, Park S, Park C, Kim KW, Yang CH. Related Articles, Links Synthetic curcumin analogs inhibit activator protein-1 transcription and tumor-induced angiogenesis.Biochem Biophys Res Commun. 2004 Aug 20;321(2):337-44. PMID: 15358181 [PubMed - indexed for MEDLINE]

271: Lin JK. Related Articles, Links Suppression of protein kinase C and nuclear oncogene expression as possible action mechanisms of cancer chemoprevention by Curcumin.Arch Pharm Res. 2004 Jul;27(7):683-92. Review. PMID: 15356994 [PubMed - indexed for MEDLINE]

272: Wei SC, Lin YS, Tsao PN, Wu-Tsai JJ, Wu CH, Wong JM. Related Articles, Links Comparison of the anti-proliferation and apoptosis-induction activities of sulindac, celecoxib, curcumin, and nifedipine in mismatch repair-deficient cell lines.J Formos Med Assoc. 2004 Aug;103(8):599-606. PMID: 15340658 [PubMed - indexed for MEDLINE]

273: Narayan S. Related Articles, Links Curcumin, a multi-functional chemopreventive agent, blocks growth of colon cancer cells by targeting beta-catenin-mediated transactivation and cell-cell adhesion pathways.J Mol Histol. 2004 Mar;35(3):301-7. Review. PMID: 15339049 [PubMed - indexed for MEDLINE]

274: [No authors listed] Related Articles, Links Erratum to: Aggarwal et al., Inhibition of Growth and Survival of Human Head and Neck Squamous Cell Carcinoma Cells by Curcumin via Modulation of Nuclear Factor-kappaB Signalling. Int J Cancer 2004; 111:679-692.Int J Cancer. 2004 Aug 12; [Epub ahead of print] PMID: 15316937 [PubMed - as supplied by publisher]

275: Eckert RL, Crish JF, Efimova T, Balasubramanian S. Related Articles, Links Antioxidants regulate normal human keratinocyte differentiation.Biochem Pharmacol. 2004 Sep 15;68(6):1125-31. PMID: 15313409 [PubMed - indexed for MEDLINE]

276: Wijnands MV, van Erk MJ, Doornbos RP, Krul CA, Woutersen RA. Related Articles, Links Do aberrant crypt foci have predictive value for the occurrence of colorectal tumours? Potential of gene expression profiling in tumours.Food Chem Toxicol. 2004 Oct;42(10):1629-39.


































PMID: 15304309 [PubMed - indexed for MEDLINE]277: Koo JY, Kim HJ, Jung KO, Park KY. Related Articles, Links

Curcumin inhibits the growth of AGS human gastric carcinoma cells in vitro and shows synergism with 5-fluorouracil.J Med Food. 2004 Summer;7(2):117-21. PMID: 15298755 [PubMed - indexed for MEDLINE]

278: Pillai SP, Mitscher LA, Menon SR, Pillai CA, Shankel DM. Related Articles, Links Antimutagenic/antioxidant activity of green tea components and related compounds.J Environ Pathol Toxicol Oncol. 1999;18(3):147-58. PMID: 15281227 [PubMed - indexed for MEDLINE]

279: Surh YJ, Park KK, Chun KS, Lee LJ, Lee E, Lee SS. Related Articles, Links Anti-tumor-promoting activities of selected pungent phenolic substances present in ginger.J Environ Pathol Toxicol Oncol. 1999;18(2):131-9. PMID: 15281225 [PubMed - indexed for MEDLINE]

280: Scott DW, Loo G. Related Articles, Links Curcumin-induced GADD153 gene up-regulation in human colon cancer cells.Carcinogenesis. 2004 Nov;25(11):2155-64. Epub 2004 Jul 22. PMID: 15271854 [PubMed - in process]

281: Danilenko M, Studzinski GP. Related Articles, Links Enhancement by other compounds of the anti-cancer activity of vitamin D(3) and its analogs.Exp Cell Res. 2004 Aug 15;298(2):339-58. Review. PMID: 15265684 [PubMed - indexed for MEDLINE]

282: Collett GP, Campbell FC. Related Articles, Links Curcumin induces c-jun N-terminal kinase-dependent apoptosis in HCT116 human colon cancer cells.Carcinogenesis. 2004 Nov;25(11):2183-9. Epub 2004 Jul 15. PMID: 15256484 [PubMed - in process]

283: Bobrovnikova-Marjon EV, Marjon PL, Barbash O, Vander Jagt DL, Abcouwer SF.


Expression of angiogenic factors vascular endothelial growth factor and interleukin-8/CXCL8 is highly responsive to ambient glutamine availability: role of nuclear factor-kappaB and activating protein-1.Cancer Res. 2004 Jul 15;64(14):4858-69. PMID: 15256456 [PubMed - indexed for MEDLINE]

284: Aggarwal S, Takada Y, Singh S, Myers JN, Aggarwal BB. Related Articles, Links Inhibition of growth and survival of human head and neck squamous cell carcinoma cells by curcumin via modulation of nuclear factor-kappaB signaling.Int J Cancer. 2004 Sep 20;111(5):679-92. Erratum in: Int J Cancer. 2004 Dec 20;112(6):1086. PMID: 15252836 [PubMed - indexed for MEDLINE]

285: Deeb D, Jiang H, Gao X, Hafner MS, Wong H, Divine G, Chapman RA, Dulchavsky SA, Gautam SC.


Curcumin sensitizes prostate cancer cells to tumor necrosis factor-related apoptosis-inducing ligand/Apo2L by inhibiting nuclear factor-kappaB through suppression of IkappaBalpha phosphorylation.Mol Cancer Ther. 2004 Jul;3(7):803-12. PMID: 15252141 [PubMed - indexed for MEDLINE]

286: Indap MA, Barkume MS. Related Articles, Links Efficacies of plant phenolic compounds on sodium butyrate induced anti-tumour activity.Indian J Exp Biol. 2003 Aug;41(8):861-4. PMID: 15248485 [PubMed - indexed for MEDLINE]

287: Holy J. Related Articles, Links



































Curcumin inhibits cell motility and alters microfilament organization and function in prostate cancer cells.Cell Motil Cytoskeleton. 2004 Aug;58(4):253-68. PMID: 15236356 [PubMed - indexed for MEDLINE]

288: Odot J, Albert P, Carlier A, Tarpin M, Devy J, Madoulet C. Related Articles, Links In vitro and in vivo anti-tumoral effect of curcumin against melanoma cells.Int J Cancer. 2004 Sep 1;111(3):381-7. PMID: 15221965 [PubMed - indexed for MEDLINE]

289: Banerji A, Chakrabarti J, Mitra A, Chatterjee A. Related Articles, Links Effect of curcumin on gelatinase A (MMP-2) activity in B16F10 melanoma cells.Cancer Lett. 2004 Aug 10;211(2):235-42. PMID: 15219947 [PubMed - indexed for MEDLINE]

290: Adams BK, Ferstl EM, Davis MC, Herold M, Kurtkaya S, Camalier RF, Hollingshead MG, Kaur G, Sausville EA, Rickles FR, Snyder JP, Liotta DC, Shoji M.


Synthesis and biological evaluation of novel curcumin analogs as anti-cancer and anti-angiogenesis agents.Bioorg Med Chem. 2004 Jul 15;12(14):3871-83. PMID: 15210154 [PubMed - indexed for MEDLINE]

291: Rashmi R, Kumar S, Karunagaran D. Related Articles, Links Ectopic expression of Bcl-XL or Ku70 protects human colon cancer cells (SW480) against curcumin-induced apoptosis while their down-regulation potentiates it.Carcinogenesis. 2004 Oct;25(10):1867-77. Epub 2004 Jun 17. PMID: 15205359 [PubMed - indexed for MEDLINE]

292: Kwon Y, Malik M, Magnuson BA. Related Articles, Links Inhibition of colonic aberrant crypt foci by curcumin in rats is affected by age.Nutr Cancer. 2004;48(1):37-43. PMID: 15203376 [PubMed - indexed for MEDLINE]

293: Reddy BS. Related Articles, Links Studies with the azoxymethane-rat preclinical model for assessing colon tumor development and chemoprevention.Environ Mol Mutagen. 2004;44(1):26-35. Review. PMID: 15199544 [PubMed - indexed for MEDLINE]

294: Zheng M, Ekmekcioglu S, Walch ET, Tang CH, Grimm EA. Related Articles, Links Inhibition of nuclear factor-kappaB and nitric oxide by curcumin induces G2/M cell cycle arrest and apoptosis in human melanoma cells.Melanoma Res. 2004 Jun;14(3):165-71. PMID: 15179184 [PubMed - indexed for MEDLINE]

295: Zheng L, Tong Q, Wu C. Related Articles, Links Growth-inhibitory effects of curcumin on ovary cancer cells and its mechanisms.J Huazhong Univ Sci Technolog Med Sci. 2004;24(1):55-8. PMID: 15165116 [PubMed - indexed for MEDLINE]

296: Liontas A, Yeger H. Related Articles, Links Curcumin and resveratrol induce apoptosis and nuclear translocation and activation of p53 in human neuroblastoma.Anticancer Res. 2004 Mar-Apr;24(2B):987-98. PMID: 15161054 [PubMed - indexed for MEDLINE]

297: Nakano K, Nakayachi T, Yasumoto E, Morshed SR, Hashimoto K, Kikuchi H, Nishikawa H, Sugiyama K, Amano O, Kawase M, Sakagami H.


Induction of apoptosis by beta-diketones in human tumor cells.Anticancer Res. 2004 Mar-Apr;24(2B):711-7. PMID: 15161016 [PubMed - indexed for MEDLINE]

298: Fujisawa S, Atsumi T, Ishihara M, Kadoma Y. Related Articles, Links Cytotoxicity, ROS-generation activity and radical-scavenging activity of curcumin and related compounds.Anticancer Res. 2004 Mar-Apr;24(2B):563-9.






































PMID: 15160995 [PubMed - indexed for MEDLINE]299: Radhakrishna Pillai G, Srivastava AS, Hassanein TI, Chauhan DP, Carrier

E.Related Articles, Links

Induction of apoptosis in human lung cancer cells by curcumin.Cancer Lett. 2004 May 28;208(2):163-70. PMID: 15142674 [PubMed - indexed for MEDLINE]

300: Van Erk MJ, Teuling E, Staal YC, Huybers S, Van Bladeren PJ, Aarts JM, Van Ommen B.


Time- and dose-dependent effects of curcumin on gene expression in human colon cancer cells.J Carcinog. 2004 May 12;3(1):8. PMID: 15140256 [PubMed - as supplied by publisher]

301: Jeong WS, Kim IW, Hu R, Kong AN. Related Articles, Links Modulatory properties of various natural chemopreventive agents on the activation of NF-kappaB signaling pathway.Pharm Res. 2004 Apr;21(4):661-70. PMID: 15139523 [PubMed - indexed for MEDLINE]

302: Jeong WS, Kim IW, Hu R, Kong AN. Related Articles, Links Modulation of AP-1 by natural chemopreventive compounds in human colon HT-29 cancer cell line.Pharm Res. 2004 Apr;21(4):649-60. PMID: 15139522 [PubMed - indexed for MEDLINE]

303: Dorai T, Dutcher JP, Dempster DW, Wiernik PH. Related Articles, Links Therapeutic potential of curcumin in prostate cancer--V: Interference with the osteomimetic properties of hormone refractory C4-2B prostate cancer cells.Prostate. 2004 Jun 15;60(1):1-17. PMID: 15129424 [PubMed - indexed for MEDLINE]

304: Singh S, Bhat MK. Related Articles, Links Carboplatin induces apoptotic cell death through downregulation of constitutively active nuclear factor-kappaB in human HPV-18 E6-positive HEp-2 cells.Biochem Biophys Res Commun. 2004 May 28;318(2):346-53. PMID: 15120608 [PubMed - indexed for MEDLINE]

305: Chan WH, Wu HJ. Related Articles, Links Anti-apoptotic effects of curcumin on photosensitized human epidermal carcinoma A431 cells.J Cell Biochem. 2004 May 1;92(1):200-12. PMID: 15095415 [PubMed - indexed for MEDLINE]

306: Moos PJ, Edes K, Mullally JE, Fitzpatrick FA. Related Articles, Links Curcumin impairs tumor suppressor p53 function in colon cancer cells.Carcinogenesis. 2004 Sep;25(9):1611-7. Epub 2004 Apr 16. PMID: 15090465 [PubMed - indexed for MEDLINE]

307: Limtrakul P, Anuchapreeda S, Buddhasukh D. Related Articles, Links Modulation of human multidrug-resistance MDR-1 gene by natural curcuminoids.BMC Cancer. 2004 Apr 17;4:13. PMID: 15090070 [PubMed - indexed for MEDLINE]

308: Zheng LD, Tong QS, Tao KX, Wang L, Zhang B. Related Articles, Links [Effects of Smac gene overexpression on chemotherapeutic sensitivity of gastric cancer cell line MKN-45]Ai Zheng. 2004 Apr;23(4):361-6. Chinese. PMID: 15087019 [PubMed - indexed for MEDLINE]

309: Ambegaokar SS, Wu L, Alamshahi K, Lau J, Jazayeri L, Chan S, Khanna P, Hsieh E, Timiras PS.


Curcumin inhibits dose-dependently and time-dependently neuroglial cell proliferation and growth.Neuro Endocrinol Lett. 2003 Dec;24(6):469-73.





































PMID: 15073579 [PubMed - indexed for MEDLINE]310: Hong J, Bose M, Ju J, Ryu JH, Chen X, Sang S, Lee MJ, Yang CS. Related Articles, Links

Modulation of arachidonic acid metabolism by curcumin and related beta-diketone derivatives: effects on cytosolic phospholipase A(2), cyclooxygenases and 5-lipoxygenase.Carcinogenesis. 2004 Sep;25(9):1671-9. Epub 2004 Apr 8. PMID: 15073046 [PubMed - indexed for MEDLINE]

311: Bharti AC, Shishodia S, Reuben JM, Weber D, Alexanian R, Raj-Vadhan S, Estrov Z, Talpaz M, Aggarwal BB.


Nuclear factor-kappaB and STAT3 are constitutively active in CD138+ cells derived from multiple myeloma patients, and suppression of these transcription factors leads to apoptosis.Blood. 2004 Apr 15;103(8):3175-84. Epub 2003 Dec 18. PMID: 15070700 [PubMed - indexed for MEDLINE]

312: Depeille P, Cuq P, Mary S, Passagne I, Evrard A, Cupissol D, Vian L. Related Articles, Links Glutathione S-transferase M1 and multidrug resistance protein 1 act in synergy to protect melanoma cells from vincristine effects.Mol Pharmacol. 2004 Apr;65(4):897-905. PMID: 15044619 [PubMed - indexed for MEDLINE]

313: Dickinson DA, Iles KE, Wigley AF, Forman HJ. Related Articles, Links Analysis of transcription factor remodeling in phase II gene expression with curcumin.Methods Enzymol. 2004;378:302-18. Review. No abstract available. PMID: 15038977 [PubMed - indexed for MEDLINE]

314: Martin-Cordero C, Lopez-Lazaro M, Galvez M, Ayuso MJ. Related Articles, Links Curcumin as a DNA topoisomerase II poison.J Enzyme Inhib Med Chem. 2003 Dec;18(6):505-9. PMID: 15008515 [PubMed - indexed for MEDLINE]

315: Garcea G, Jones DJ, Singh R, Dennison AR, Farmer PB, Sharma RA, Steward WP, Gescher AJ, Berry DP.


Detection of curcumin and its metabolites in hepatic tissue and portal blood of patients following oral administration.Br J Cancer. 2004 Mar 8;90(5):1011-5. PMID: 14997198 [PubMed - indexed for MEDLINE]

316: Chendil D, Ranga RS, Meigooni D, Sathishkumar S, Ahmed MM. Related Articles, Links Curcumin confers radiosensitizing effect in prostate cancer cell line PC-3.Oncogene. 2004 Feb 26;23(8):1599-607. PMID: 14985701 [PubMed - indexed for MEDLINE]

317: Park S, Chung S, Kim KM, Jung KC, Park C, Hahm ER, Yang CH. Related Articles, Links Determination of binding constant of transcription factor myc-max/max-max and E-box DNA: the effect of inhibitors on the binding.Biochim Biophys Acta. 2004 Feb 24;1670(3):217-28. PMID: 14980448 [PubMed - indexed for MEDLINE]

318: Youssef KM, El-Sherbeny MA, El-Shafie FS, Farag HA, Al-Deeb OA, Awadalla SA.


Synthesis of curcumin analogues as potential antioxidant, cancer chemopreventive agents.Arch Pharm (Weinheim). 2004 Jan;337(1):42-54. PMID: 14760627 [PubMed - indexed for MEDLINE]

319: Agarwal B, Swaroop P, Protiva P, Raj SV, Shirin H, Holt PR. Related Articles, Links Cox-2 is needed but not sufficient for apoptosis induced by Cox-2 selective inhibitors in colon cancer cells.Apoptosis. 2003 Dec;8(6):649-54. PMID: 14739610 [PubMed - indexed for MEDLINE]

320: Polasa K, Naidu AN, Ravindranath I, Krishnaswamy K. Related Articles, Links




































Inhibition of B(a)P induced strand breaks in presence of curcumin.Mutat Res. 2004 Feb 14;557(2):203-13. PMID: 14729375 [PubMed - indexed for MEDLINE]

321: Wang Q, Wieder R. Related Articles, Links All-trans retinoic acid potentiates Taxotere-induced cell death mediated by Jun N-terminal kinase in breast cancer cells.Oncogene. 2004 Jan 15;23(2):426-33. PMID: 14724571 [PubMed - indexed for MEDLINE]

322: Chen HW, Yu SL, Chen JJ, Li HN, Lin YC, Yao PL, Chou HY, Chien CT, Chen WJ, Lee YT, Yang PC.


Anti-invasive gene expression profile of curcumin in lung adenocarcinoma based on a high throughput microarray analysis.Mol Pharmacol. 2004 Jan;65(1):99-110. PMID: 14722241 [PubMed - indexed for MEDLINE]

323: Shigeoka Y, Igishi T, Matsumoto S, Nakanishi H, Kodani M, Yasuda K, Hitsuda Y, Shimizu E.


Sulindac sulfide and caffeic acid phenethyl ester suppress the motility of lung adenocarcinoma cells promoted by transforming growth factor-beta through Akt inhibition.J Cancer Res Clin Oncol. 2004 Mar;130(3):146-52. Epub 2003 Dec 23. PMID: 14691717 [PubMed - indexed for MEDLINE]

324: Tanaka Y, Kobayashi H, Suzuki M, Kanayama N, Terao T. Related Articles, Links Transforming growth factor-beta1-dependent urokinase up-regulation and promotion of invasion are involved in Src-MAPK-dependent signaling in human ovarian cancer cells.J Biol Chem. 2004 Mar 5;279(10):8567-76. Epub 2003 Dec 15. PMID: 14676209 [PubMed - indexed for MEDLINE]

325: Tokunaga T, Morshed SR, Otsuki S, Takayama F, Satoh T, Hashimoto K, Yasui T, Ogawa S, Kanegae H, Yokote Y, Akahane K, Kashimata M, Satoh K, Sakagami H.


Effect of antioxidants, oxidants, metals and saliva on cytotoxicity induction by sodium fluoride.Anticancer Res. 2003 Sep-Oct;23(5A):3719-26. PMID: 14666669 [PubMed - indexed for MEDLINE]

326: Wallace JM. Related Articles, Links Nutritional and botanical modulation of the inflammatory cascade--eicosanoids, cyclooxygenases, and lipoxygenases--as an adjunct in cancer therapy.Integr Cancer Ther. 2002 Mar;1(1):7-37; discussion 37. Review. PMID: 14664746 [PubMed - indexed for MEDLINE]

327: Ohashi Y, Tsuchiya Y, Koizumi K, Sakurai H, Saiki I. Related Articles, Links Prevention of intrahepatic metastasis by curcumin in an orthotopic implantation model.Oncology. 2003;65(3):250-8. PMID: 14657599 [PubMed - indexed for MEDLINE]

328: Ferguson LR, Lim IF, Pearson AE, Ralph J, Harris PJ. Related Articles, Links Bacterial antimutagenesis by hydroxycinnamic acids from plant cell walls.Mutat Res. 2003 Dec 9;542(1-2):49-58. PMID: 14644353 [PubMed - indexed for MEDLINE]

329: Gao C, Ding Z, Liang B, Chen N, Cheng D. Related Articles, Links [Study on the effects of curcumin on angiogenesis]Zhong Yao Cai. 2003 Jul;26(7):499-502. Chinese. PMID: 14650061 [PubMed - indexed for MEDLINE]

330: Di GH, Li HC, Shen ZZ, Shao ZM. Related Articles, Links [Analysis of anti-proliferation of curcumin on human breast cancer cells and its mechanism]




































Zhonghua Yi Xue Za Zhi. 2003 Oct 25;83(20):1764-8. Chinese. PMID: 14642080 [PubMed - indexed for MEDLINE]

331: Baek OS, Kang OH, Choi YA, Choi SC, Kim TH, Nah YH, Kwon DY, Kim YK, Kim YH, Bae KH, Lim JP, Lee YM.


Curcumin inhibits protease-activated receptor-2 and -4-mediated mast cell activation.Clin Chim Acta. 2003 Dec;338(1-2):135-41. PMID: 14637278 [PubMed - indexed for MEDLINE]

332: Conney AH. Related Articles, Links Enzyme induction and dietary chemicals as approaches to cancer chemoprevention: the Seventh DeWitt S. Goodman Lecture.Cancer Res. 2003 Nov 1;63(21):7005-31. PMID: 14612489 [PubMed - indexed for MEDLINE]

333: Teng LS, Fahey TJ 3rd. Related Articles, Links Can inhibition of telomerase increase pancreatic cancer cell's susceptibility to chemotherapeutic reagents?Hepatobiliary Pancreat Dis Int. 2002 Feb;1(1):155-60. PMID: 14607648 [PubMed - indexed for MEDLINE]

334: Rashmi R, Kumar S, Karunagaran D. Related Articles, Links Ectopic expression of Hsp70 confers resistance and silencing its expression sensitizes human colon cancer cells to curcumin-induced apoptosis.Carcinogenesis. 2004 Feb;25(2):179-87. Epub 2003 Nov 6. PMID: 14604899 [PubMed - indexed for MEDLINE]

335: Mizushina Y, Hirota M, Murakami C, Ishidoh T, Kamisuki S, Shimazaki N, Takemura M, Perpelescu M, Suzuki M, Yoshida H, Sugawara F, Koiwai O, Sakaguchi K.


Some anti-chronic inflammatory compounds are DNA polymerase lambda-specific inhibitors.Biochem Pharmacol. 2003 Nov 15;66(10):1935-44. PMID: 14599551 [PubMed - indexed for MEDLINE]

336: Sinha R, Anderson DE, McDonald SS, Greenwald P. Related Articles, Links Cancer risk and diet in India.J Postgrad Med. 2003 Jul-Sep;49(3):222-8. Review. PMID: 14597785 [PubMed - indexed for MEDLINE]

337: Adlerz L, Beckman M, Holback S, Tehranian R, Cortes Toro V, Iverfeldt K.


Accumulation of the amyloid precursor-like protein APLP2 and reduction of APLP1 in retinoic acid-differentiated human neuroblastoma cells upon curcumin-induced neurite retraction.Brain Res Mol Brain Res. 2003 Nov 6;119(1):62-72. PMID: 14597230 [PubMed - indexed for MEDLINE]

338: Basu NK, Ciotti M, Hwang MS, Kole L, Mitra PS, Cho JW, Owens IS. Related Articles, Links Differential and special properties of the major human UGT1-encoded gastrointestinal UDP-glucuronosyltransferases enhance potential to control chemical uptake.J Biol Chem. 2004 Jan 9;279(2):1429-41. Epub 2003 Oct 13. PMID: 14557274 [PubMed - indexed for MEDLINE]

339: Duvoix A, Morceau F, Delhalle S, Schmitz M, Schnekenburger M, Galteau MM, Dicato M, Diederich M.


Induction of apoptosis by curcumin: mediation by glutathione S-transferase P1-1 inhibition.Biochem Pharmacol. 2003 Oct 15;66(8):1475-83. PMID: 14555224 [PubMed - indexed for MEDLINE]

340: Bielak-Mijewska A, Piwocka K, Magalska A, Sikora E. Related Articles, Links P-glycoprotein expression does not change the apoptotic pathway induced by curcumin in HL-60 cells.Cancer Chemother Pharmacol. 2004 Feb;53(2):179-85. Epub 2003 Oct 3.




































PMID: 14530869 [PubMed - indexed for MEDLINE]

341: Verma SP, Goldin BR. Related Articles, Links Copper modulates activities of genistein, nitric oxide, and curcumin in breast tumor cells.Biochem Biophys Res Commun. 2003 Oct 10;310(1):104-8. PMID: 14511655 [PubMed - indexed for MEDLINE]

342: Chan WH, Wu CC, Yu JS. Related Articles, Links Curcumin inhibits UV irradiation-induced oxidative stress and apoptotic biochemical changes in human epidermoid carcinoma A431 cells.J Cell Biochem. 2003 Oct 1;90(2):327-38. PMID: 14505349 [PubMed - indexed for MEDLINE]

343: Bharti AC, Donato N, Aggarwal BB. Related Articles, Links Curcumin (diferuloylmethane) inhibits constitutive and IL-6-inducible STAT3 phosphorylation in human multiple myeloma cells.J Immunol. 2003 Oct 1;171(7):3863-71. PMID: 14500688 [PubMed - indexed for MEDLINE]

344: Shishu, Singla AK, Kaur IP. Related Articles, Links Inhibitory effect of dibenzoylmethane on mutagenicity of food-derived heterocyclic amine mutagens.Phytomedicine. 2003;10(6-7):575-82. PMID: 13678246 [PubMed - indexed for MEDLINE]

345: Chen YN, Cheng CC, Chen JC, Tsauer W, Hsu SL. Related Articles, Links Norcantharidin-induced apoptosis is via the extracellular signal-regulated kinase and c-Jun-NH2-terminal kinase signaling pathways in human hepatoma HepG2 cells.Br J Pharmacol. 2003 Oct;140(3):461-70. Epub 2003 Sep 1. PMID: 12970086 [PubMed - indexed for MEDLINE]

346: Garcea G, Dennison AR, Steward WP, Berry DP. Related Articles, Links Chemoprevention of gastrointestinal malignancies.ANZ J Surg. 2003 Sep;73(9):680-6. Review. PMID: 12956781 [PubMed - indexed for MEDLINE]

347: Mitchell TM. Related Articles, Links Correspondence re: Somasundaram et al., Dietary curcumin inhibits chemotherapy-induced apoptosis in models of human breast cancer. Cancer Res., 62: 3868-3875, 2002.Cancer Res. 2003 Aug 15;63(16):5165-6; author reply 5166-7. No abstract available. PMID: 12941849 [PubMed - indexed for MEDLINE]

348: Chen JC, Hwang JM, Chen GW, Tsou MF, Hsia TC, Chung JG. Related Articles, Links Curcumin decreases the DNA adduct formation, arylamines N-acetyltransferase activity and gene expression in human colon tumor cells (colo 205).In Vivo. 2003 May-Jun;17(3):301-9. PMID: 12929584 [PubMed - indexed for MEDLINE]

349: Kirana C, McIntosh GH, Record IR, Jones GP. Related Articles, Links Antitumor activity of extract of Zingiber aromaticum and its bioactive sesquiterpenoid zerumbone.Nutr Cancer. 2003;45(2):218-25. PMID: 12881017 [PubMed - indexed for MEDLINE]

350: van der Logt EM, Roelofs HM, Nagengast FM, Peters WH. Related Articles, Links Induction of rat hepatic and intestinal UDP-glucuronosyltransferases by naturally occurring dietary anticarcinogens.Carcinogenesis. 2003 Oct;24(10):1651-6. Epub 2003 Jul 17. PMID: 12869420 [PubMed - indexed for MEDLINE]

351: Kumar AP, Garcia GE, Ghosh R, Rajnarayanan RV, Alworth WL, Slaga TJ.


4-Hydroxy-3-methoxybenzoic acid methyl ester: a curcumin derivative targets Akt/NF kappa B cell survival signaling pathway: potential for prostate cancer



































management.Neoplasia. 2003 May-Jun;5(3):255-66. PMID: 12869308 [PubMed - indexed for MEDLINE]

352: Ghosh J. Related Articles, Links Inhibition of arachidonate 5-lipoxygenase triggers prostate cancer cell death through rapid activation of c-Jun N-terminal kinase.Biochem Biophys Res Commun. 2003 Jul 25;307(2):342-9. PMID: 12859962 [PubMed - indexed for MEDLINE]

353: Park JI, Lee MG, Cho K, Park BJ, Chae KS, Byun DS, Ryu BK, Park YK, Chi SG.


Transforming growth factor-beta1 activates interleukin-6 expression in prostate cancer cells through the synergistic collaboration of the Smad2, p38-NF-kappaB, JNK, and Ras signaling pathways.Oncogene. 2003 Jul 10;22(28):4314-32. PMID: 12853969 [PubMed - indexed for MEDLINE]

354: Kumar S, Misra A, Tripathi S, Misra K. Related Articles, Links Study on curcumin-oligonucleotide conjugate as a probable anticancer agent: its hybridisation with telomere target sequence 5'-GGGATTGGGATT-3'.Nucleic Acids Res Suppl. 2001;(1):137-8. PMID: 12836302 [PubMed - indexed for MEDLINE]

355: Woo JH, Kim YH, Choi YJ, Kim DG, Lee KS, Bae JH, Min DS, Chang JS, Jeong YJ, Lee YH, Park JW, Kwon TK.


Molecular mechanisms of curcumin-induced cytotoxicity: induction of apoptosis through generation of reactive oxygen species, down-regulation of Bcl-XL and IAP, the release of cytochrome c and inhibition of Akt.Carcinogenesis. 2003 Jul;24(7):1199-208. Epub 2003 May 9. PMID: 12807727 [PubMed - indexed for MEDLINE]

356: Shishodia S, Potdar P, Gairola CG, Aggarwal BB. Related Articles, Links Curcumin (diferuloylmethane) down-regulates cigarette smoke-induced NF-kappaB activation through inhibition of IkappaBalpha kinase in human lung epithelial cells: correlation with suppression of COX-2, MMP-9 and cyclin D1.Carcinogenesis. 2003 Jul;24(7):1269-79. Epub 2003 May 9. PMID: 12807725 [PubMed - indexed for MEDLINE]

357: Cheng Y, Li HL, Wang HF, Sun HF, Liu YF, Peng SX, Liu KX, Guo ZY. Related Articles, Links Inhibition of nicotine-DNA adduct formation in mice by six dietary constituents.Food Chem Toxicol. 2003 Jul;41(7):1045-50. PMID: 12804663 [PubMed - indexed for MEDLINE]

358: Skrzypczak-Jankun E, Zhou K, McCabe NP, Selman SH, Jankun J. Related Articles, Links Structure of curcumin in complex with lipoxygenase and its significance in cancer.Int J Mol Med. 2003 Jul;12(1):17-24. PMID: 12792803 [PubMed - indexed for MEDLINE]

359: Shukla Y, Arora A. Related Articles, Links Suppression of altered hepatic foci development by curcumin in wistar rats.Nutr Cancer. 2003;45(1):53-9. PMID: 12791505 [PubMed - indexed for MEDLINE]

360: Chen YS, Ho CC, Cheng KC, Tyan YS, Hung CF, Tan TW, Chung JG. Related Articles, Links Curcumin inhibited the arylamines N-acetyltransferase activity, gene expression and DNA adduct formation in human lung cancer cells (A549).Toxicol In Vitro. 2003 Jun;17(3):323-33. PMID: 12781211 [PubMed - indexed for MEDLINE]

361: Perkins S, Clarke AR, Steward W, Gescher A. Related Articles, Links Age-related difference in susceptibility of Apc(Min/+) mice towards the chemopreventive efficacy of dietary aspirin and curcumin.Br J Cancer. 2003 May 6;88(9):1480-3. PMID: 12778080 [PubMed - indexed for MEDLINE]

































362: Das R, Mahabeleshwar GH, Kundu GC. Related Articles, Links Osteopontin stimulates cell motility and nuclear factor kappaB-mediated secretion of urokinase type plasminogen activator through phosphatidylinositol 3-kinase/Akt signaling pathways in breast cancer cells.J Biol Chem. 2003 Aug 1;278(31):28593-606. Epub 2003 May 27. PMID: 12771144 [PubMed - indexed for MEDLINE]

363: Corpet DE, Pierre F. Related Articles, Links Point: From animal models to prevention of colon cancer. Systematic review of chemoprevention in min mice and choice of the model system.Cancer Epidemiol Biomarkers Prev. 2003 May;12(5):391-400. Review. PMID: 12750232 [PubMed - indexed for MEDLINE]

364: Vietri M, Pietrabissa A, Mosca F, Spisni R, Pacifici GM. Related Articles, Links Curcumin is a potent inhibitor of phenol sulfotransferase (SULT1A1) in human liver and extrahepatic tissues.Xenobiotica. 2003 Apr;33(4):357-63. PMID: 12745871 [PubMed - indexed for MEDLINE]

365: Leyon PV, Kuttan G. Related Articles, Links Studies on the role of some synthetic curcuminoid derivatives in the inhibition of tumour specific angiogenesis.J Exp Clin Cancer Res. 2003 Mar;22(1):77-83. PMID: 12725326 [PubMed - indexed for MEDLINE]

366: Roy M, Chakraborty S, Siddiqi M, Bhattacharya RK. Related Articles, Links Induction of Apoptosis in Tumor Cells by Natural Phenolic Compounds.Asian Pac J Cancer Prev. 2002;3(1):61-67. PMID: 12718610 [PubMed - as supplied by publisher]

367: Iqbal M, Sharma SD, Okazaki Y, Fujisawa M, Okada S. Related Articles, Links Dietary supplementation of curcumin enhances antioxidant and phase II metabolizing enzymes in ddY male mice: possible role in protection against chemical carcinogenesis and toxicity.Pharmacol Toxicol. 2003 Jan;92(1):33-8. PMID: 12710595 [PubMed - indexed for MEDLINE]

368: Caughey B, Raymond LD, Raymond GJ, Maxson L, Silveira J, Baron GS. Related Articles, Links Inhibition of protease-resistant prion protein accumulation in vitro by curcumin.J Virol. 2003 May;77(9):5499-502. PMID: 12692251 [PubMed - indexed for MEDLINE]

369: Chaudhary LR, Hruska KA. Related Articles, Links Inhibition of cell survival signal protein kinase B/Akt by curcumin in human prostate cancer cells.J Cell Biochem. 2003 May 1;89(1):1-5. PMID: 12682902 [PubMed - indexed for MEDLINE]

370: Aggarwal BB, Kumar A, Bharti AC. Related Articles, Links Anticancer potential of curcumin: preclinical and clinical studies.Anticancer Res. 2003 Jan-Feb;23(1A):363-98. Review. PMID: 12680238 [PubMed - indexed for MEDLINE]

371: Gajate C, An F, Mollinedo F. Related Articles, Links Rapid and selective apoptosis in human leukemic cells induced by Aplidine through a Fas/CD95- and mitochondrial-mediated mechanism.Clin Cancer Res. 2003 Apr;9(4):1535-45. PMID: 12684430 [PubMed - indexed for MEDLINE]

372: Leu TH, Maa MC. Related Articles, Links The molecular mechanisms for the antitumorigenic effect of curcumin.Curr Med Chem Anticancer Agents. 2002 May;2(3):357-70. Review. PMID: 12678737 [PubMed - indexed for MEDLINE]

373: Ray S, Chattopadhyay N, Mitra A, Siddiqi M, Chatterjee A. Related Articles, Links




































Curcumin exhibits antimetastatic properties by modulating integrin receptors, collagenase activity, and expression of Nm23 and E-cadherin.J Environ Pathol Toxicol Oncol. 2003;22(1):49-58. PMID: 12678405 [PubMed - indexed for MEDLINE]

374: Chen Y, Wu Y, He J, Chen W. Related Articles, Links The experimental and clinical study on the effect of curcumin on cell cycle proteins and regulating proteins of apoptosis in acute myelogenous leukemia.J Huazhong Univ Sci Technolog Med Sci. 2002;22(4):295-8. PMID: 12674762 [PubMed - indexed for MEDLINE]

375: Sah NK, Munshi A, Kurland JF, McDonnell TJ, Su B, Meyn RE. Related Articles, Links Translation inhibitors sensitize prostate cancer cells to apoptosis induced by tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) by activating c-Jun N-terminal kinase.J Biol Chem. 2003 Jun 6;278(23):20593-602. Epub 2003 Mar 27. PMID: 12663665 [PubMed - indexed for MEDLINE]

376: Danilenko M, Wang Q, Wang X, Levy J, Sharoni Y, Studzinski GP. Related Articles, Links Carnosic acid potentiates the antioxidant and prodifferentiation effects of 1alpha,25-dihydroxyvitamin D3 in leukemia cells but does not promote elevation of basal levels of intracellular calcium.Cancer Res. 2003 Mar 15;63(6):1325-32. PMID: 12649194 [PubMed - indexed for MEDLINE]

377: Rashmi R, Santhosh Kumar TR, Karunagaran D. Related Articles, Links Human colon cancer cells differ in their sensitivity to curcumin-induced apoptosis and heat shock protects them by inhibiting the release of apoptosis-inducing factor and caspases.FEBS Lett. 2003 Mar 13;538(1-3):19-24. PMID: 12633846 [PubMed - indexed for MEDLINE]

378: Gerhauser C, Klimo K, Heiss E, Neumann I, Gamal-Eldeen A, Knauft J, Liu GY, Sitthimonchai S, Frank N.


Mechanism-based in vitro screening of potential cancer chemopreventive agents.Mutat Res. 2003 Feb-Mar;523-524:163-72. PMID: 12628514 [PubMed - indexed for MEDLINE]

379: Frank N, Knauft J, Amelung F, Nair J, Wesch H, Bartsch H. Related Articles, Links No prevention of liver and kidney tumors in Long-Evans Cinnamon rats by dietary curcumin, but inhibition at other sites and of metastases.Mutat Res. 2003 Feb-Mar;523-524:127-35. PMID: 12628510 [PubMed - indexed for MEDLINE]

380: Keum YS, Han SS, Chun KS, Park KK, Park JH, Lee SK, Surh YJ. Related Articles, Links Inhibitory effects of the ginsenoside Rg3 on phorbol ester-induced cyclooxygenase-2 expression, NF-kappaB activation and tumor promotion.Mutat Res. 2003 Feb-Mar;523-524:75-85. PMID: 12628505 [PubMed - indexed for MEDLINE]

381: Iqbal M, Okazaki Y, Okada S. Related Articles, Links In vitro curcumin modulates ferric nitrilotriacetate (Fe-NTA) and hydrogen peroxide (H2O2)-induced peroxidation of microsomal membrane lipids and DNA damage.Teratog Carcinog Mutagen. 2003;Suppl 1:151-60. PMID: 12616605 [PubMed - indexed for MEDLINE]

382: Li H, Cheng Y, Wang H, Sun H, Liu Y, Liu K, Peng S. Related Articles, Links Inhibition of nitrobenzene-induced DNA and hemoglobin adductions by dietary constituents.Appl Radiat Isot. 2003 Mar;58(3):291-8. PMID: 12595006 [PubMed - indexed for MEDLINE]

383: Li N, Chen X, Han C, Chen J. Related Articles, Links
































[Chemopreventive effect of tea and curcumin on DMBA-induced oral carcinogenesis in hamsters]Wei Sheng Yan Jiu. 2002 Oct;31(5):354-7. Chinese. PMID: 12572355 [PubMed - indexed for MEDLINE]

384: Mahady GB, Pendland SL, Yun G, Lu ZZ. Related Articles, Links Turmeric (Curcuma longa) and curcumin inhibit the growth of Helicobacter pylori, a group 1 carcinogen.Anticancer Res. 2002 Nov-Dec;22(6C):4179-81. PMID: 12553052 [PubMed - indexed for MEDLINE]

385: Greenwald P, Milner JA, Anderson DE, McDonald SS. Related Articles, Links Micronutrients in cancer chemoprevention.Cancer Metastasis Rev. 2002;21(3-4):217-30. Review. PMID: 12549762 [PubMed - indexed for MEDLINE]

386: Devasena T, Rajasekaran KN, Gunasekaran G, Viswanathan P, Menon VP. Related Articles, Links Anticarcinogenic effect of bis-1,7-(2-hydroxyphenyl)-hepta-1,6-diene-3,5-dione a curcumin analog on DMH-induced colon cancer model.Pharmacol Res. 2003 Feb;47(2):133-40. PMID: 12543061 [PubMed - indexed for MEDLINE]

387: Dashwood RH. Related Articles, Links Use of transgenic and mutant animal models in the study of heterocyclic amine-induced mutagenesis and carcinogenesis.J Biochem Mol Biol. 2003 Jan 31;36(1):35-42. Review. PMID: 12542973 [PubMed - indexed for MEDLINE]

388: Deeb D, Xu YX, Jiang H, Gao X, Janakiraman N, Chapman RA, Gautam SC.


Curcumin (diferuloyl-methane) enhances tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in LNCaP prostate cancer cells.Mol Cancer Ther. 2003 Jan;2(1):95-103. PMID: 12533677 [PubMed - indexed for MEDLINE]

389: Zheng LD, Tong QS, Wu CH. Related Articles, Links [Inhibitory effects of curcumin on apoptosis of human ovary cancer cell line A2780 and its molecular mechanism]Ai Zheng. 2002 Dec;21(12):1296-300. Chinese. PMID: 12520734 [PubMed - indexed for MEDLINE]

390: Li H, Che Y, Tang W. Related Articles, Links [Effects of curcumin on proliferation and apoptosis in human hepatic cells]Zhonghua Gan Zang Bing Za Zhi. 2002 Dec;10(6):449-51. Chinese. PMID: 12502450 [PubMed - indexed for MEDLINE]

391: Dorai T, Gehani N, Katz A. Related Articles, Links Therapeutic potential of curcumin in human prostate cancer-I. curcumin induces apoptosis in both androgen-dependent and androgen-independent prostate cancer cells.Prostate Cancer Prostatic Dis. 2000 Aug;3(2):84-93. PMID: 12497104 [PubMed - as supplied by publisher]

392: Kim JH, Shim JS, Lee SK, Kim KW, Rha SY, Chung HC, Kwon HJ. Related Articles, Links Microarray-based analysis of anti-angiogenic activity of demethoxycurcumin on human umbilical vein endothelial cells: crucial involvement of the down-regulation of matrix metalloproteinase.Jpn J Cancer Res. 2002 Dec;93(12):1378-85. PMID: 12495478 [PubMed - indexed for MEDLINE]

393: Gukovsky I, Reyes CN, Vaquero EC, Gukovskaya AS, Pandol SJ. Related Articles, Links Curcumin ameliorates ethanol and nonethanol experimental pancreatitis.Am J Physiol Gastrointest Liver Physiol. 2003 Jan;284(1):G85-95. PMID: 12488237 [PubMed - indexed for MEDLINE]

394: Mukhopadhyay A, Banerjee S, Stafford LJ, Xia C, Liu M, Aggarwal BB. Related Articles, Links



































Curcumin-induced suppression of cell proliferation correlates with down-regulation of cyclin D1 expression and CDK4-mediated retinoblastoma protein phosphorylation.Oncogene. 2002 Dec 12;21(57):8852-61. PMID: 12483537 [PubMed - indexed for MEDLINE]

395: Gopalakrishna R, Gundimeda U. Related Articles, Links Antioxidant regulation of protein kinase C in cancer prevention.J Nutr. 2002 Dec;132(12):3819S-3823S. PMID: 12468631 [PubMed - indexed for MEDLINE]

396: Robinson TP, Ehlers T, Hubbard IV RB, Bai X, Arbiser JL, Goldsmith DJ, Bowen JP.


Design, synthesis, and biological evaluation of angiogenesis inhibitors: aromatic enone and dienone analogues of curcumin.Bioorg Med Chem Lett. 2003 Jan 6;13(1):115-7. PMID: 12467629 [PubMed - indexed for MEDLINE]

397: Jaiswal AS, Marlow BP, Gupta N, Narayan S. Related Articles, Links Beta-catenin-mediated transactivation and cell-cell adhesion pathways are important in curcumin (diferuylmethane)-induced growth arrest and apoptosis in colon cancer cells.Oncogene. 2002 Dec 5;21(55):8414-27. PMID: 12466962 [PubMed - indexed for MEDLINE]

398: Heath DD, Pruitt MA, Brenner DE, Rock CL. Related Articles, Links Curcumin in plasma and urine: quantitation by high-performance liquid chromatography.J Chromatogr B Analyt Technol Biomed Life Sci. 2003 Jan 5;783(1):287-95. PMID: 12450549 [PubMed - indexed for MEDLINE]

399: Chan MM, Fong D, Soprano KJ, Holmes WF, Heverling H. Related Articles, Links Inhibition of growth and sensitization to cisplatin-mediated killing of ovarian cancer cells by polyphenolic chemopreventive agents.J Cell Physiol. 2003 Jan;194(1):63-70. PMID: 12447990 [PubMed - indexed for MEDLINE]

400: Ozen N, Uslu E, Ozen M, Aydin S, Altug T, Belce A, Kokoglu E. Related Articles, Links Curcumin's effects on sialic acid level and sialidase activity in Ehrlich ascites tumor bearing mice.Tohoku J Exp Med. 2002 Aug;197(4):221-7. PMID: 12434997 [PubMed - indexed for MEDLINE]

Items 381 - 400 of 649

401: Steriti R. Related Articles, Links Nutritional support for chronic myelogenous and other leukemias: a review of the scientific literature.Altern Med Rev. 2002 Oct;7(5):404-9. Review. PMID: 12410624 [PubMed - indexed for MEDLINE]

402: Kawabe S, Nishikawa T, Munshi A, Roth JA, Chada S, Meyn RE. Related Articles, Links Adenovirus-mediated mda-7 gene expression radiosensitizes non-small cell lung cancer cells via TP53-independent mechanisms.Mol Ther. 2002 Nov;6(5):637-44. PMID: 12409262 [PubMed - indexed for MEDLINE]

403: Bouma M, Nuijen B, Jansen MT, Sava G, Bult A, Beijnen JH. Related Articles, Links Photostability profiles of the experimental antimetastatic ruthenium complex NAMI-A.J Pharm Biomed Anal. 2002 Nov 7;30(4):1287-96. PMID: 12408919 [PubMed - indexed for MEDLINE]

404: Wu Y, Chen Y, Xu J, Lu L. Related Articles, Links Anticancer activities of curcumin on human Burkitt's lymphoma.Zhonghua Zhong Liu Za Zhi. 2002 Jul;24(4):348-52.

































PMID: 12408761 [PubMed - indexed for MEDLINE]405: Ohtsu H, Xiao Z, Ishida J, Nagai M, Wang HK, Itokawa H, Su CY, Shih C,

Chiang T, Chang E, Lee Y, Tsai MY, Chang C, Lee KH.Related Articles, Links

Antitumor agents. 217. Curcumin analogues as novel androgen receptor antagonists with potential as anti-prostate cancer agents.J Med Chem. 2002 Nov 7;45(23):5037-42. PMID: 12408714 [PubMed - indexed for MEDLINE]

406: Chen Z, Clark S, Birkeland M, Sung CM, Lago A, Liu R, Kirkpatrick R, Johanson K, Winkler JD, Hu E.


Induction and superinduction of growth arrest and DNA damage gene 45 (GADD45) alpha and beta messenger RNAs by histone deacetylase inhibitors trichostatin A (TSA) and butyrate in SW620 human colon carcinoma cells.Cancer Lett. 2002 Dec 15;188(1-2):127-40. PMID: 12406558 [PubMed - indexed for MEDLINE]

407: Bharti AC, Donato N, Singh S, Aggarwal BB. Related Articles, Links Curcumin (diferuloylmethane) down-regulates the constitutive activation of nuclear factor-kappa B and IkappaBalpha kinase in human multiple myeloma cells, leading to suppression of proliferation and induction of apoptosis.Blood. 2003 Feb 1;101(3):1053-62. Epub 2002 Sep 5. PMID: 12393461 [PubMed - indexed for MEDLINE]

408: Dinkova-Kostova AT. Related Articles, Links Protection against cancer by plant phenylpropenoids: induction of mammalian anticarcinogenic enzymes.Mini Rev Med Chem. 2002 Dec;2(6):595-610. Review. PMID: 12370043 [PubMed - indexed for MEDLINE]

409: Rinaldi AL, Morse MA, Fields HW, Rothas DA, Pei P, Rodrigo KA, Renner RJ, Mallery SR.


Curcumin activates the aryl hydrocarbon receptor yet significantly inhibits (-)-benzo(a)pyrene-7R-trans-7,8-dihydrodiol bioactivation in oral squamous cell carcinoma cells and oral mucosa.Cancer Res. 2002 Oct 1;62(19):5451-6. PMID: 12359752 [PubMed - indexed for MEDLINE]

410: Gururaj AE, Belakavadi M, Venkatesh DA, Marme D, Salimath BP. Related Articles, Links Molecular mechanisms of anti-angiogenic effect of curcumin.Biochem Biophys Res Commun. 2002 Oct 4;297(4):934-42. PMID: 12359244 [PubMed - indexed for MEDLINE]

411: Han SS, Keum YS, Seo HJ, Surh YJ. Related Articles, Links Curcumin suppresses activation of NF-kappaB and AP-1 induced by phorbol ester in cultured human promyelocytic leukemia cells.J Biochem Mol Biol. 2002 May 31;35(3):337-42. PMID: 12297018 [PubMed - indexed for MEDLINE]

412: Nakamura K, Yasunaga Y, Segawa T, Ko D, Moul JW, Srivastava S, Rhim JS.


Curcumin down-regulates AR gene expression and activation in prostate cancer cell lines.Int J Oncol. 2002 Oct;21(4):825-30. PMID: 12239622 [PubMed - indexed for MEDLINE]

413: Sakano K, Kawanishi S. Related Articles, Links Metal-mediated DNA damage induced by curcumin in the presence of human cytochrome P450 isozymes.Arch Biochem Biophys. 2002 Sep 15;405(2):223-30. PMID: 12220536 [PubMed - indexed for MEDLINE]

414: Hidaka H, Ishiko T, Furuhashi T, Kamohara H, Suzuki S, Miyazaki M, Ikeda O, Mita S, Setoguchi T, Ogawa M.


Curcumin inhibits interleukin 8 production and enhances interleukin 8 receptor expression on the cell surface:impact on human pancreatic carcinoma cell growth by




































autocrine regulation.Cancer. 2002 Sep 15;95(6):1206-14. PMID: 12216086 [PubMed - indexed for MEDLINE]

415: Ishida J, Ohtsu H, Tachibana Y, Nakanishi Y, Bastow KF, Nagai M, Wang HK, Itokawa H, Lee KH.


Antitumor agents. Part 214: synthesis and evaluation of curcumin analogues as cytotoxic agents.Bioorg Med Chem. 2002 Nov;10(11):3481-7. PMID: 12213462 [PubMed - indexed for MEDLINE]

416: Jiang DZ, Xie QY, Wang QR. Related Articles, Links [Effect of curcumin on the proliferation of murine CFU-GM and WEHI-3B cells]Hunan Yi Ke Da Xue Xue Bao. 2000 Jun 28;25(3):216-8. Chinese. PMID: 12212145 [PubMed - indexed for MEDLINE]

417: Devasena T, Rajasekaran KN, Menon VP. Related Articles, Links Bis-1,7-(2-hydroxyphenyl)-hepta-1,6-diene-3,5-dione (a curcumin analog) ameliorates DMH-induced hepatic oxidative stress during colon carcinogenesis.Pharmacol Res. 2002 Jul;46(1):39-45. PMID: 12208119 [PubMed - indexed for MEDLINE]

418: Chun KS, Park KK, Lee J, Kang M, Surh YJ. Related Articles, Links Inhibition of mouse skin tumor promotion by anti-inflammatory diarylheptanoids derived from Alpinia oxyphylla Miquel (Zingiberaceae).Oncol Res. 2002;13(1):37-45. PMID: 12201673 [PubMed - indexed for MEDLINE]

419: Chauhan DP. Related Articles, Links Chemotherapeutic potential of curcumin for colorectal cancer.Curr Pharm Des. 2002;8(19):1695-706. Review. PMID: 12171541 [PubMed - indexed for MEDLINE]

420: Anuchapreeda S, Leechanachai P, Smith MM, Ambudkar SV, Limtrakul PN.


Modulation of P-glycoprotein expression and function by curcumin in multidrug-resistant human KB cells.Biochem Pharmacol. 2002 Aug 15;64(4):573-82. PMID: 12167476 [PubMed - indexed for MEDLINE]

421: Santibanez JF, Guerrero J, Quintanilla M, Fabra A, Martinez J. Related Articles, Links Transforming growth factor-beta1 modulates matrix metalloproteinase-9 production through the Ras/MAPK signaling pathway in transformed keratinocytes.Biochem Biophys Res Commun. 2002 Aug 16;296(2):267-73. PMID: 12163012 [PubMed - indexed for MEDLINE]

422: Li N, Chen X, Liao J, Yang G, Wang S, Josephson Y, Han C, Chen J, Huang MT, Yang CS.


Inhibition of 7,12-dimethylbenz[a]anthracene (DMBA)-induced oral carcinogenesis in hamsters by tea and curcumin.Carcinogenesis. 2002 Aug;23(8):1307-13. PMID: 12151348 [PubMed - indexed for MEDLINE]

423: Yoshida S, Kawaguchi H, Sato S, Ueda R, Furukawa K. Related Articles, Links An anti-GD2 monoclonal antibody enhances apoptotic effects of anti-cancer drugs against small cell lung cancer cells via JNK (c-Jun terminal kinase) activation.Jpn J Cancer Res. 2002 Jul;93(7):816-24. PMID: 12149148 [PubMed - indexed for MEDLINE]

424: John VD, Kuttan G, Krishnankutty K. Related Articles, Links Anti-tumour studies of metal chelates of synthetic curcuminoids.J Exp Clin Cancer Res. 2002 Jun;21(2):219-24. PMID: 12148581 [PubMed - indexed for MEDLINE]

425: Mullally JE, Fitzpatrick FA. Related Articles, Links




































Pharmacophore model for novel inhibitors of ubiquitin isopeptidases that induce p53-independent cell death.Mol Pharmacol. 2002 Aug;62(2):351-8. PMID: 12130688 [PubMed - indexed for MEDLINE]

426: [No authors listed] Related Articles, Links Anti-cancer agents. Curry for cancer?TreatmentUpdate. 2000 Jan;11(10):9. No abstract available. PMID: 12125639 [PubMed - indexed for MEDLINE]

427: Li D, Zimmerman TL, Thevananther S, Lee HY, Kurie JM, Karpen SJ. Related Articles, Links Interleukin-1 beta-mediated suppression of RXR:RAR transactivation of the Ntcp promoter is JNK-dependent.J Biol Chem. 2002 Aug 30;277(35):31416-22. Epub 2002 Jun 24. PMID: 12105223 [PubMed - indexed for MEDLINE]

428: Ramachandran C, Fonseca HB, Jhabvala P, Escalon EA, Melnick SJ. Related Articles, Links Curcumin inhibits telomerase activity through human telomerase reverse transcritpase in MCF-7 breast cancer cell line.Cancer Lett. 2002 Oct 8;184(1):1-6. PMID: 12104041 [PubMed - indexed for MEDLINE]

429: Somasundaram S, Edmund NA, Moore DT, Small GW, Shi YY, Orlowski RZ.


Dietary curcumin inhibits chemotherapy-induced apoptosis in models of human breast cancer.Cancer Res. 2002 Jul 1;62(13):3868-75. PMID: 12097302 [PubMed - indexed for MEDLINE]

430: Reddy BS, Rao CV. Related Articles, Links Novel approaches for colon cancer prevention by cyclooxygenase-2 inhibitors.J Environ Pathol Toxicol Oncol. 2002;21(2):155-64. Review. PMID: 12086402 [PubMed - indexed for MEDLINE]

431: Fenton JI, Wolff MS, Orth MW, Hord NG. Related Articles, Links Membrane-type matrix metalloproteinases mediate curcumin-induced cell migration in non-tumorigenic colon epithelial cells differing in Apc genotype.Carcinogenesis. 2002 Jun;23(6):1065-70. PMID: 12082030 [PubMed - indexed for MEDLINE]

432: Surh YJ. Related Articles, Links Anti-tumor promoting potential of selected spice ingredients with antioxidative and anti-inflammatory activities: a short review.Food Chem Toxicol. 2002 Aug;40(8):1091-7. Review. PMID: 12067569 [PubMed - indexed for MEDLINE]

433: Holy JM. Related Articles, Links Curcumin disrupts mitotic spindle structure and induces micronucleation in MCF-7 breast cancer cells.Mutat Res. 2002 Jun 27;518(1):71-84. PMID: 12063069 [PubMed - indexed for MEDLINE]

434: Inano H, Onoda M. Related Articles, Links Radioprotective action of curcumin extracted from Curcuma longa LINN: inhibitory effect on formation of urinary 8-hydroxy-2'-deoxyguanosine, tumorigenesis, but not mortality, induced by gamma-ray irradiation.Int J Radiat Oncol Biol Phys. 2002 Jul 1;53(3):735-43. PMID: 12062620 [PubMed - indexed for MEDLINE]

435: Perkins S, Verschoyle RD, Hill K, Parveen I, Threadgill MD, Sharma RA, Williams ML, Steward WP, Gescher AJ.


Chemopreventive efficacy and pharmacokinetics of curcumin in the min/+ mouse, a model of familial adenomatous polyposis.Cancer Epidemiol Biomarkers Prev. 2002 Jun;11(6):535-40. PMID: 12050094 [PubMed - indexed for MEDLINE]

436: Chuang SE, Yeh PY, Lu YS, Lai GM, Liao CM, Gao M, Cheng AL. Related Articles, Links




































Basal levels and patterns of anticancer drug-induced activation of nuclear factor-kappaB (NF-kappaB), and its attenuation by tamoxifen, dexamethasone, and curcumin in carcinoma cells.Biochem Pharmacol. 2002 May 1;63(9):1709-16. PMID: 12007574 [PubMed - indexed for MEDLINE]

437: Kim DS, Kim DS, Oppel MN. Related Articles, Links Shogaols from Zingiber officinale protect IMR32 human neuroblastoma and normal human umbilical vein endothelial cells from beta-amyloid(25-35) insult.Planta Med. 2002 Apr;68(4):375-6. PMID: 11988870 [PubMed - indexed for MEDLINE]

438: Hour TC, Chen J, Huang CY, Guan JY, Lu SH, Pu YS. Related Articles, Links Curcumin enhances cytotoxicity of chemotherapeutic agents in prostate cancer cells by inducing p21(WAF1/CIP1) and C/EBPbeta expressions and suppressing NF-kappaB activation.Prostate. 2002 May 15;51(3):211-8. PMID: 11967955 [PubMed - indexed for MEDLINE]

439: Gescher AJ, Sharma RA, Steward WP. Related Articles, Links Cancer chemoprevention by dietary constituents: a tale of failure and promise.Lancet Oncol. 2001 Jun;2(6):371-9. Review. PMID: 11905754 [PubMed - indexed for MEDLINE]

440: Afaq F, Adhami VM, Ahmad N, Mukhtar H. Related Articles, Links Botanical antioxidants for chemoprevention of photocarcinogenesis.Front Biosci. 2002 Apr 1;7:d784-92. Review. PMID: 11897547 [PubMed - indexed for MEDLINE]

441: Hsu CH, Chuang SE, Hergenhahn M, Kuo ML, Lin JK, Hsieh CY, Cheng AL.


Pre-clinical and early-phase clinical studies of curcumin as chemopreventive agent for endemic cancers in Taiwan.Gan To Kagaku Ryoho. 2002 Feb;29 Suppl 1:194-200. No abstract available. PMID: 11890105 [PubMed - indexed for MEDLINE]

442: Shao ZM, Shen ZZ, Liu CH, Sartippour MR, Go VL, Heber D, Nguyen M. Related Articles, Links Curcumin exerts multiple suppressive effects on human breast carcinoma cells.Int J Cancer. 2002 Mar 10;98(2):234-40. PMID: 11857414 [PubMed - indexed for MEDLINE]

443: Choudhuri T, Pal S, Agwarwal ML, Das T, Sa G. Related Articles, Links Curcumin induces apoptosis in human breast cancer cells through p53-dependent Bax induction.FEBS Lett. 2002 Feb 13;512(1-3):334-40. PMID: 11852106 [PubMed - indexed for MEDLINE]

444: Ikezaki S, Nishikawa A, Furukawa F, Kudo K, Nakamura H, Tamura K, Mori H.


Chemopreventive effects of curcumin on glandular stomach carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine and sodium chloride in rats.Anticancer Res. 2001 Sep-Oct;21(5):3407-11. PMID: 11848501 [PubMed - indexed for MEDLINE]

445: Ireson CR, Jones DJ, Orr S, Coughtrie MW, Boocock DJ, Williams ML, Farmer PB, Steward WP, Gescher AJ.


Metabolism of the cancer chemopreventive agent curcumin in human and rat intestine.Cancer Epidemiol Biomarkers Prev. 2002 Jan;11(1):105-11. PMID: 11815407 [PubMed - indexed for MEDLINE]

446: Khar A, Ali AM, Pardhasaradhi BV, Varalakshmi CH, Anjum R, Kumari AL.


Induction of stress response renders human tumor cell lines resistant to curcumin-mediated apoptosis: role of reactive oxygen intermediates.




































Cell Stress Chaperones. 2001 Oct;6(4):368-76. PMID: 11795474 [PubMed - indexed for MEDLINE]

447: Inano H, Onoda M. Related Articles, Links Prevention of radiation-induced mammary tumors.Int J Radiat Oncol Biol Phys. 2002 Jan 1;52(1):212-23. PMID: 11777641 [PubMed - indexed for MEDLINE]

448: Yan C, Li C, Tian F. Related Articles, Links [Fibronectin induces matrix metalloproteinase-2 expression in ovarian cancer cells]Zhonghua Zhong Liu Za Zhi. 2000 Mar;22(2):109-12. Chinese. PMID: 11776634 [PubMed - indexed for MEDLINE]

449: Mukhopadhyay A, Bueso-Ramos C, Chatterjee D, Pantazis P, Aggarwal BB.


Curcumin downregulates cell survival mechanisms in human prostate cancer cell lines.Oncogene. 2001 Nov 15;20(52):7597-609. PMID: 11753638 [PubMed - indexed for MEDLINE]

450: Plummer SM, Hill KA, Festing MF, Steward WP, Gescher AJ, Sharma RA.


Clinical development of leukocyte cyclooxygenase 2 activity as a systemic biomarker for cancer chemopreventive agents.Cancer Epidemiol Biomarkers Prev. 2001 Dec;10(12):1295-9. PMID: 11751448 [PubMed - indexed for MEDLINE]

451: Wargovich MJ. Related Articles, Links Colon cancer chemoprevention with ginseng and other botanicals.J Korean Med Sci. 2001 Dec;16 Suppl:S81-6. Review. PMID: 11748382 [PubMed - indexed for MEDLINE]

452: Kondo A, Koshihara Y, Togari A. Related Articles, Links Signal transduction system for interleukin-6 synthesis stimulated by lipopolysaccharide in human osteoblasts.J Interferon Cytokine Res. 2001 Nov;21(11):943-50. PMID: 11747626 [PubMed - indexed for MEDLINE]

453: Bush JA, Cheung KJ Jr, Li G. Related Articles, Links Curcumin induces apoptosis in human melanoma cells through a Fas receptor/caspase-8 pathway independent of p53.Exp Cell Res. 2001 Dec 10;271(2):305-14. PMID: 11716543 [PubMed - indexed for MEDLINE]

454: Cheng AL, Hsu CH, Lin JK, Hsu MM, Ho YF, Shen TS, Ko JY, Lin JT, Lin BR, Ming-Shiang W, Yu HS, Jee SH, Chen GS, Chen TM, Chen CA, Lai MK, Pu YS, Pan MH, Wang YJ, Tsai CC, Hsieh CY.


Phase I clinical trial of curcumin, a chemopreventive agent, in patients with high-risk or pre-malignant lesions.Anticancer Res. 2001 Jul-Aug;21(4B):2895-900. PMID: 11712783 [PubMed - indexed for MEDLINE]

455: Ichiki K, Mitani N, Doki Y, Hara H, Misaki T, Saiki I. Related Articles, Links Regulation of activator protein-1 activity in the mediastinal lymph node metastasis of lung cancer.Clin Exp Metastasis. 2000;18(7):539-45. PMID: 11688958 [PubMed - indexed for MEDLINE]

456: Batth BK, Tripathi R, Srinivas UK. Related Articles, Links Curcumin-induced differentiation of mouse embryonal carcinoma PCC4 cells.Differentiation. 2001 Sep;68(2-3):133-40. PMID: 11686235 [PubMed - indexed for MEDLINE]

457: Pal S, Choudhuri T, Chattopadhyay S, Bhattacharya A, Datta GK, Das T, Sa G.


Mechanisms of curcumin-induced apoptosis of Ehrlich's ascites carcinoma cells.Biochem Biophys Res Commun. 2001 Nov 2;288(3):658-65. PMID: 11676493 [PubMed - indexed for MEDLINE]







































458: Goel A, Boland CR, Chauhan DP. Related Articles, Links Specific inhibition of cyclooxygenase-2 (COX-2) expression by dietary curcumin in HT-29 human colon cancer cells.Cancer Lett. 2001 Oct 30;172(2):111-8. PMID: 11566484 [PubMed - indexed for MEDLINE]

459: Levi MS, Borne RF, Williamson JS. Related Articles, Links A review of cancer chemopreventive agents.Curr Med Chem. 2001 Sep;8(11):1349-62. Review. PMID: 11562271 [PubMed - indexed for MEDLINE]

460: Sindhwani P, Hampton JA, Baig MM, Keck R, Selman SH. Related Articles, Links Curcumin prevents intravesical tumor implantation of the MBT-2 tumor cell line in C3H mice.J Urol. 2001 Oct;166(4):1498-501. PMID: 11547120 [PubMed - indexed for MEDLINE]

461: Piwocka K, Jaruga E, Skierski J, Gradzka I, Sikora E. Related Articles, Links Effect of glutathione depletion on caspase-3 independent apoptosis pathway induced by curcumin in Jurkat cells.Free Radic Biol Med. 2001 Sep 1;31(5):670-8. PMID: 11522452 [PubMed - indexed for MEDLINE]

462: Surh YJ, Chun KS, Cha HH, Han SS, Keum YS, Park KK, Lee SS. Related Articles, Links Molecular mechanisms underlying chemopreventive activities of anti-inflammatory phytochemicals: down-regulation of COX-2 and iNOS through suppression of NF-kappa B activation.Mutat Res. 2001 Sep 1;480-481:243-68. Review. PMID: 11506818 [PubMed - indexed for MEDLINE]

463: Mori H, Niwa K, Zheng Q, Yamada Y, Sakata K, Yoshimi N. Related Articles, Links Cell proliferation in cancer prevention; effects of preventive agents on estrogen-related endometrial carcinogenesis model and on an in vitro model in human colorectal cells.Mutat Res. 2001 Sep 1;480-481:201-7. PMID: 11506814 [PubMed - indexed for MEDLINE]

464: Smith WA, Freeman JW, Gupta RC. Related Articles, Links Effect of chemopreventive agents on DNA adduction induced by the potent mammary carcinogen dibenzo[a,l]pyrene in the human breast cells MCF-7.Mutat Res. 2001 Sep 1;480-481:97-108. PMID: 11506803 [PubMed - indexed for MEDLINE]

465: Araujo CC, Leon LL. Related Articles, Links Biological activities of Curcuma longa L.Mem Inst Oswaldo Cruz. 2001 Jul;96(5):723-8. Review. PMID: 11500779 [PubMed - indexed for MEDLINE]

466: Lin CC, Ho CT, Huang MT. Related Articles, Links Mechanistic studies on the inhibitory action of dietary dibenzoylmethane, a beta-diketone analogue of curcumin, on 7,12-dimethylbenz[a]anthracene-induced mammary tumorigenesis.Proc Natl Sci Counc Repub China B. 2001 Jul;25(3):158-65. PMID: 11480771 [PubMed - indexed for MEDLINE]

467: Jaga K, Duvvi H. Related Articles, Links Risk reduction for DDT toxicity and carcinogenesis through dietary modification.J R Soc Health. 2001 Jun;121(2):107-13. Review. PMID: 11467202 [PubMed - indexed for MEDLINE]

468: Jovanovic SV, Boone CW, Steenken S, Trinoga M, Kaskey RB. Related Articles, Links How curcumin works preferentially with water soluble antioxidants.J Am Chem Soc. 2001 Apr 4;123(13):3064-8. PMID: 11457017 [PubMed - indexed for MEDLINE]


































469: Sharma RA, McLelland HR, Hill KA, Ireson CR, Euden SA, Manson MM, Pirmohamed M, Marnett LJ, Gescher AJ, Steward WP.


Pharmacodynamic and pharmacokinetic study of oral Curcuma extract in patients with colorectal cancer.Clin Cancer Res. 2001 Jul;7(7):1894-900. PMID: 11448902 [PubMed - indexed for MEDLINE]

470: Lin CC, Lu YP, Lou YR, Ho CT, Newmark HH, MacDonald C, Singletary KW, Huang MT.


Inhibition by dietary dibenzoylmethane of mammary gland proliferation, formation of DMBA-DNA adducts in mammary glands, and mammary tumorigenesis in Sencar mice.Cancer Lett. 2001 Jul 26;168(2):125-32. PMID: 11403916 [PubMed - indexed for MEDLINE]

471: Dorai T, Cao YC, Dorai B, Buttyan R, Katz AE. Related Articles, Links Therapeutic potential of curcumin in human prostate cancer. III. Curcumin inhibits proliferation, induces apoptosis, and inhibits angiogenesis of LNCaP prostate cancer cells in vivo.Prostate. 2001 Jun 1;47(4):293-303. PMID: 11398177 [PubMed - indexed for MEDLINE]

472: Jiang Y, Satoh K, Aratsu C, Kobayashi N, Unten S, Kakuta H, Kikuchi H, Nishikawa H, Ochiai K, Sakagami H.


Combination effect of lignin F and natural products.Anticancer Res. 2001 Mar-Apr;21(2A):965-70. PMID: 11396189 [PubMed - indexed for MEDLINE]

473: Moragoda L, Jaszewski R, Majumdar AP. Related Articles, Links Curcumin induced modulation of cell cycle and apoptosis in gastric and colon cancer cells.Anticancer Res. 2001 Mar-Apr;21(2A):873-8. PMID: 11396178 [PubMed - indexed for MEDLINE]

474: Lin JK, Lin-Shiau SY. Related Articles, Links Mechanisms of cancer chemoprevention by curcumin.Proc Natl Sci Counc Repub China B. 2001 Apr;25(2):59-66. Review. PMID: 11370761 [PubMed - indexed for MEDLINE]

475: Sharma RA, Ireson CR, Verschoyle RD, Hill KA, Williams ML, Leuratti C, Manson MM, Marnett LJ, Steward WP, Gescher A.


Effects of dietary curcumin on glutathione S-transferase and malondialdehyde-DNA adducts in rat liver and colon mucosa: relationship with drug levels.Clin Cancer Res. 2001 May;7(5):1452-8. PMID: 11350917 [PubMed - indexed for MEDLINE]

476: Collett GP, Robson CN, Mathers JC, Campbell FC. Related Articles, Links Curcumin modifies Apc(min) apoptosis resistance and inhibits 2-amino 1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) induced tumour formation in Apc(min) mice.Carcinogenesis. 2001 May;22(5):821-5. PMID: 11323404 [PubMed - indexed for MEDLINE]

477: Busquets S, Carbo N, Almendro V, Quiles MT, Lopez-Soriano FJ, Argiles JM.


Curcumin, a natural product present in turmeric, decreases tumor growth but does not behave as an anticachectic compound in a rat model.Cancer Lett. 2001 Jun 10;167(1):33-8. PMID: 11323096 [PubMed - indexed for MEDLINE]

478: Chen YC, Tsai SH, Shen SC, Lin JK, Lee WR. Related Articles, Links Alternative activation of extracellular signal-regulated protein kinases in curcumin and arsenite-induced HSP70 gene expression in human colorectal carcinoma cells.Eur J Cell Biol. 2001 Mar;80(3):213-21. PMID: 11322385 [PubMed - indexed for MEDLINE]

479: Pan MH, Chang WL, Lin-Shiau SY, Ho CT, Lin JK. Related Articles, Links






































Induction of apoptosis by garcinol and curcumin through cytochrome c release and activation of caspases in human leukemia HL-60 cells.J Agric Food Chem. 2001 Mar;49(3):1464-74. PMID: 11312881 [PubMed - indexed for MEDLINE]

480: Imaida K, Tamano S, Kato K, Ikeda Y, Asamoto M, Takahashi S, Nir Z, Murakoshi M, Nishino H, Shirai T.


Lack of chemopreventive effects of lycopene and curcumin on experimental rat prostate carcinogenesis.Carcinogenesis. 2001 Mar;22(3):467-72. PMID: 11238188 [PubMed - indexed for MEDLINE]

481: Xu K, Thornalley PJ. Related Articles, Links Signal transduction activated by the cancer chemopreventive isothiocyanates: cleavage of BID protein, tyrosine phosphorylation and activation of JNK.Br J Cancer. 2001 Mar 2;84(5):670-3. PMID: 11237388 [PubMed - indexed for MEDLINE]

482: Lin JK, Pan MH, Lin-Shiau SY. Related Articles, Links Recent studies on the biofunctions and biotransformations of curcumin.Biofactors. 2000;13(1-4):153-8. Review. PMID: 11237176 [PubMed - indexed for MEDLINE]

483: Limtrakul P, Anuchapreeda S, Lipigorngoson S, Dunn FW. Related Articles, Links Inhibition of carcinogen induced c-Ha-ras and c-fos proto-oncogenes expression by dietary curcumin.BMC Cancer. 2001;1:1. Epub 2001 Jan 17. PMID: 11231886 [PubMed - indexed for MEDLINE]

484: Ahmad N, Katiyar SK, Mukhtar H. Related Articles, Links Antioxidants in chemoprevention of skin cancer.Curr Probl Dermatol. 2001;29:128-39. Review. No abstract available. PMID: 11225193 [PubMed - indexed for MEDLINE]

485: Ireson C, Orr S, Jones DJ, Verschoyle R, Lim CK, Luo JL, Howells L, Plummer S, Jukes R, Williams M, Steward WP, Gescher A.


Characterization of metabolites of the chemopreventive agent curcumin in human and rat hepatocytes and in the rat in vivo, and evaluation of their ability to inhibit phorbol ester-induced prostaglandin E2 production.Cancer Res. 2001 Feb 1;61(3):1058-64. PMID: 11221833 [PubMed - indexed for MEDLINE]

486: Surh YJ, Han SS, Keum YS, Seo HJ, Lee SS. Related Articles, Links Inhibitory effects of curcumin and capsaicin on phorbol ester-induced activation of eukaryotic transcription factors, NF-kappaB and AP-1.Biofactors. 2000;12(1-4):107-12. PMID: 11216470 [PubMed - indexed for MEDLINE]

487: Cuendet M, Pezzuto JM. Related Articles, Links The role of cyclooxygenase and lipoxygenase in cancer chemoprevention.Drug Metabol Drug Interact. 2000;17(1-4):109-57. Review. PMID: 11201293 [PubMed - indexed for MEDLINE]

488: Kondo A, Mogi M, Koshihara Y, Togari A. Related Articles, Links Signal transduction system for interleukin-6 and interleukin-11 synthesis stimulated by epinephrine in human osteoblasts and human osteogenic sarcoma cells.Biochem Pharmacol. 2001 Feb 1;61(3):319-26. PMID: 11172736 [PubMed - indexed for MEDLINE]

489: Xu K, Thornalley PJ. Related Articles, Links Involvement of glutathione metabolism in the cytotoxicity of the phenethyl isothiocyanate and its cysteine conjugate to human leukaemia cells in vitro.Biochem Pharmacol. 2001 Jan 15;61(2):165-77. PMID: 11163331 [PubMed - indexed for MEDLINE]

490: Hadi SM, Asad SF, Singh S, Ahmad A. Related Articles, Links




































Putative mechanism for anticancer and apoptosis-inducing properties of plant-derived polyphenolic compounds.IUBMB Life. 2000 Sep;50(3):167-71. Review. PMID: 11142343 [PubMed - indexed for MEDLINE]

491: Sakagami T, Satoh K, Ishihara M, Sakagami H, Takeda F, Kochi M, Takeda M.


Effect of cobalt ion on radical intensity and cytotoxic activity of antioxidants.Anticancer Res. 2000 Sep-Oct;20(5A):3143-50. PMID: 11062735 [PubMed - indexed for MEDLINE]

492: Chuang SE, Cheng AL, Lin JK, Kuo ML. Related Articles, Links Inhibition by curcumin of diethylnitrosamine-induced hepatic hyperplasia, inflammation, cellular gene products and cell-cycle-related proteins in rats.Food Chem Toxicol. 2000 Nov;38(11):991-5. PMID: 11038236 [PubMed - indexed for MEDLINE]

493: Hossain K, Akhand AA, Kato M, Du J, Takeda K, Wu J, Takeuchi K, Liu W, Suzuki H, Nakashima I.


Arsenite induces apoptosis of murine T lymphocytes through membrane raft-linked signaling for activation of c-Jun amino-terminal kinase.J Immunol. 2000 Oct 15;165(8):4290-7. PMID: 11035063 [PubMed - indexed for MEDLINE]

494: Bhaumik S, Jyothi MD, Khar A. Related Articles, Links Differential modulation of nitric oxide production by curcumin in host macrophages and NK cells.FEBS Lett. 2000 Oct 13;483(1):78-82. PMID: 11033360 [PubMed - indexed for MEDLINE]

495: Skrzypczak-Jankun E, McCabe NP, Selman SH, Jankun J. Related Articles, Links Curcumin inhibits lipoxygenase by binding to its central cavity: theoretical and X-ray evidence.Int J Mol Med. 2000 Nov;6(5):521-6. PMID: 11029517 [PubMed - indexed for MEDLINE]

496: Inano H, Onoda M, Inafuku N, Kubota M, Kamada Y, Osawa T, Kobayashi H, Wakabayashi K.


Potent preventive action of curcumin on radiation-induced initiation of mammary tumorigenesis in rats.Carcinogenesis. 2000 Oct;21(10):1835-41. PMID: 11023541 [PubMed - indexed for MEDLINE]

497: Ushida J, Sugie S, Kawabata K, Pham QV, Tanaka T, Fujii K, Takeuchi H, Ito Y, Mori H.


Chemopreventive effect of curcumin on N-nitrosomethylbenzylamine-induced esophageal carcinogenesis in rats.Jpn J Cancer Res. 2000 Sep;91(9):893-8. PMID: 11011116 [PubMed - indexed for MEDLINE]

498: Awasthi S, Pandya U, Singhal SS, Lin JT, Thiviyanathan V, Seifert WE Jr, Awasthi YC, Ansari GA.


Curcumin-glutathione interactions and the role of human glutathione S-transferase P1-1.Chem Biol Interact. 2000 Aug 15;128(1):19-38. PMID: 10996298 [PubMed - indexed for MEDLINE]

499: Mariadason JM, Corner GA, Augenlicht LH. Related Articles, Links Genetic reprogramming in pathways of colonic cell maturation induced by short chain fatty acids: comparison with trichostatin A, sulindac, and curcumin and implications for chemoprevention of colon cancer.Cancer Res. 2000 Aug 15;60(16):4561-72. PMID: 10969808 [PubMed - indexed for MEDLINE]

500: Ramsewak RS, DeWitt DL, Nair MG. Related Articles, Links Cytotoxicity, antioxidant and anti-inflammatory activities of curcumins I-III from





































Curcuma longa.Phytomedicine. 2000 Jul;7(4):303-8. PMID: 10969724 [PubMed - indexed for MEDLINE]

Thangapazham RL, Sharma A, Maheshwari RK. Links Multiple ...ummafrapp.de/krebs/Curcumin/Curcumin and Cancer-1.pdf · 2: Kamath R, Jiang Z, Sun G, Yalowich JC, Rajasekaran B. Related

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