Department of Neglected Tropical Disease Control (NTD) Neglected Tropical Diseases New challenges for prequalification Neglected Tropical Diseases New challenges for prequalification Dr Lorenzo Savioli Director NTD department Dr Lorenzo Savioli Director NTD department
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Department of Neglected Tropical Disease Control (NTD)
Neglected Tropical DiseasesNew challenges for prequalification
Neglected Tropical DiseasesNew challenges for prequalification
Dr Lorenzo SavioliDirector NTD department
Dr Lorenzo SavioliDirector NTD department
Department of Neglected Tropical Disease Control (NTD)
Outline of the presentationOutline of the presentation
� Characteristics of NTDs. Public health interventions
� List of NTDs targeted by WHO and TDR
� Existing partnerships for access and for R&D
� Assessment of current interventions and needs
� Possible way forward for discussion
Department of Neglected Tropical Disease Control (NTD)
NTDs NTDs -- the characteristics the characteristics
Group of circa 15 tropical infectious diseases which cause immense suffering:
• life-long disabilities
• impair childhood growth and development• promote poverty, impair education and economic development
• do not receive attention and funding as do “the
big three” (AIDS, TB, malaria)
• Evidence that they increase morbidity and transmission of “the big three”
• The “bottom billion” are most at risk affecting the poorest of the poor in rural and urban areas of low-income countries
Department of Neglected Tropical Disease Control (NTD)
The Neglected Tropical Diseases The Neglected Tropical Diseases
Deaths DALYs
Neglected Diseases20%
Other infectiousdiseases29%
HIV/TB/Malaria51%
Neglected Diseases24%
Other infectiousdiseases30%
HIV/TB/Malaria46%
530,000 Deaths Annually 57 Million DALYs
Diseases of Poverty with High Disease Burden
Department of Neglected Tropical Disease Control (NTD)
African trypanosomiasis
Leishmaniasis
Dengue
Chagas Disease
Rabies
Buruli ulcer
Yaws
Leprosy
LF
Schistosomiasis
Trachoma
Soil-transmitted helminths
Schistosomiasis
Lymphatic filariasis
Onchocerciasis
Trachoma
FBTs, cysticercosis, …
Transmission control
Water & Environmental sanitation
Integrated Vector Management
Access tocase management,
surgery and chronic care
Education for behavioural change
Veterinary Public Health
Preventive chemotherapy
Public health interventions
Link with other large scale interventions
and their delivery channels
Department of Neglected Tropical Disease Control (NTD)