MB304 Industrial & Environmental Biotechnology Module 1 Industrial Microbiology 1 Prepared by: Ms. Lim Yin Sze.

MB304 MB304 Industrial & Environmental Industrial & Environmental

BiotechnologyBiotechnology

Module 1Industrial Microbiology

1Prepared by: Ms. Lim Yin Sze

Chapter 1Chapter 1

Introduction Introduction to to

Industrial MicrobiologyIndustrial Microbiology

History of Industrial Microbiology

Properties of a Useful Industrial Microorganism

Major Products of Industrial Microorganism

2

Industrial MicrobiologyIndustrial Microbiology

Industrial Microbiology refers to bulk production of any organic compound derived from microorganisms.

3

History History of Industrial Microbiologyof Industrial Microbiology Industrial microbiology originated

with alcoholic fermentation processes, e.g. beer, wine.

Subsequently, microbial processes were developed for the production of pharmaceuticals, food additive, enzymes and chemicals.

Currently, methods for gene manipulation have given rise to new microbial products, most of it which are not naturally produced by the microb, e.g. human insulin.

4

Stages Products of FermentationPre -1900 Alcohol (yeast)

Vinegar1900 - 1940 Baker’s yeast

Glycerol, citric acid, lactic acid, and acetone/butanol

1940 - today Pharmaceutical products

e.g. penicillin, streptomycin1960 – today Single cell protein (SCP)1979 - today Genetically engineered products

e.g. insulin

History History of Industrial Microbiologyof Industrial Microbiology

5