Inaugural Meeting of the European ALCL Study Group June 11 th – 12 th 2010 Salzburg, Austria Laboratory for Immunological and Molecular Cancer Research IIIrd Medical Department with Hematology, Medical Oncology, Hemostaseology, Rheumatology and Infectiology of the Paracelsus Medical University Salzburg Prof. Richard Greil
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Inaugural Meeting of the European
ALCL Study Group
June 11th – 12th 2010
Salzburg, Austria
Laboratory for Immunological and Molecular Cancer ResearchIIIrd Medical Department with Hematology, Medical Oncology, Hemostaseology, Rheumatology
and Infectiology of the Paracelsus Medical University Salzburg
Prof. Richard Greil
SCIENTIFIC PROGRAM
FRIDAY, JUNE 11TH
2:00 Arrival and coffee
2:30 Introductory remarks
Plenary Talk
3:00 Giorgio Inghirami - overview
Session 1 – origins of the t(2;5) and early events in oncogenesis
3:45 Stephan Mathas – ALCL depends on NPM-ALK – or not?
4:10 Suzanne Turner – NPM-ALK induced senescence: The role of p53
4:35 Emanuela Colombo – NPM-ALK induced senescence: The role of p16
5:00 Closing remarks with coffee
5:30 Finish
6:45 Reception in at the Bibliotheksaula
7:00 Concert in the Bibliotheksaula
8:00 Dinner
SATURDAY, JUNE 12TH
9:00 Opening comments
Session 2 – Mouse models of ALK-induced malignancies
9:05 Sylivie Giuriato – Development of a conditional model for ALK-induced
lymphomagenesis
9:30 Suzanne Turner – NPM haploinsufficiency does not contribute to t(2;5)
induced lymphomagenesis
9:55 Justus Duyster – The significance of BCL-3 expression for the pathogenesis of
ALK positive ALCL
10:20 coffee
Session 3 – ALCL potential targets for therapeutic intervention
10:40 Olaf Merkel – NPM-ALK and miRNAs
11:05 Lukas Kenner – NPM-ALK and JNK
11:30 Roberto Chiarle - New insights on the role of morphology, phenotype and
angiogenesis in ALK-mediated cell transformation
11:55 Karen Pulford – immune response to ALK
12:20 Round table discussion over lunch
Funding opportunities – European framework/Marie Curie/European Science
Foundation
Exchange Programs
Collaborations
Material sharing/repository
Where should future research be directed
How often should we meet/ next venue/host
Website
Afternoon Sight seeing
Evening Meeting in the garden of the Augustine monastery who have a