Development of measurement procedure for the application of magnetic nanoparticles in surgery Datz Dániel Tutor: Antal Gasparics PhD Pázmány Péter Catholic.

Development of measurement procedure for the application of magnetic nanoparticles in

surgery

Datz DánielTutor: Antal Gasparics PhD

Pázmány Péter Catholic UniversityFaculty of Information Technology

Radiopharmaceuticals

NANOMAGDYE: The marker

• Phosphonate coupling agent stabilizes pH at 4.7 -> blood.• Simple experiment for biocompatibility• Synthesis with microbubbles -> ultrasound

contranst agent

NANOMAGDYE: The probe• Magnetic and optical sensor built together• Fluxset sensor: soft magnetic core, two coils: driving and pickup coil

• No intrinsic magnetic field: excited with a third coil: excitation coil• Nanoparticles need very strong excitation: differential excitation

Measurements on low velocities

Measurements on hand movement speed

Conclusion• At low velocities there are no significant distorting effects• At higher velocities the distorting effects are at most 10-15% of the maximum

amplitude

• The probe is completely capable of the measurements it was designed to do

• Simulation of the measurements• Algorithm for signal source localization

E-mail: [email protected]

Thank you for your attention!