10.12.15 - Gastro+ Gastrolyzer Manual Gastro+ Gastrolyzer Manual... · 3 10. To repeat breath test, press and repeat steps 5-8. 11. To return to the home screen, press. 12. To save

Gastro+ Gastrolyzer®

Scientific contributions to health.

User manual

0086

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ContentsIntendedUse......................................................................................................................................2

Introduction........................................................................................................................................2

Takingabreathtest............................................................................................................................2

Takingafacemasktest.......................................................................................................................3

Addingapatientprofile......................................................................................................................3

ConductingAutomaticPatientBreathTests......................................................................................4

ProtocolPre-setTimings.....................................................................................................................6

EditProtocolTimings..........................................................................................................................6

EditProtocolNames...........................................................................................................................6

ProtocolPre-setThresholds...............................................................................................................7

EditProtocolPre-setPositiveThresholds...........................................................................................8

TechnicalSpecification.......................................................................................................................8

SafetyInformationandDeviceSymbols...........................................................................................10

Environment.....................................................................................................................................10

InstrumentLayout............................................................................................................................11

DisplaySymbols................................................................................................................................12

WarningsandMaintenance.............................................................................................................14

Cleaning............................................................................................................................................15

Reviewinghistory.............................................................................................................................15

Changingdateandtime...................................................................................................................15

RoutineMaintenance.......................................................................................................................15

Calibration........................................................................................................................................16

Troubleshooting...............................................................................................................................16

GastroCHART™Software–ConnectingtothePC............................................................................16

ReturnsProcedure............................................................................................................................16

Spares...............................................................................................................................................17

Warranty..........................................................................................................................................17

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IntendedUseTheGastro+™Gastrolyzer® is a breathhydrogen (H2)monitor used tomeasurehydrogen levels inexpired breath. It is intended for multi-patient use by healthcare professionals in a clinicalenvironment.IntroductionH2 is generated in the intestinal lumen by bacterial action on carbohydrates in the small or largeintestine.OncetheresultantH2isdiffusedintothebloodstreamitistransportedtothealveoliandthen can be detected in expiratory air. Levitt1 demonstrated the correlation between intestinallumenH2production andH2 excretion in expiratory air. AccuratemeasurementofH2 in parts permillion (ppm) in expiratory air reveals intolerance and/or malabsorption of carbohydrates; orbacterialovergrowth.Operationofthemonitorisstraightforward.AD-piecesamplingsystemenablesend-expiredbreathto be sampled easily and hygienically, using single-use disposable SteriBreath™mouthpieces anddisposablefacemasks.TheGastro+™canbeusedtoaidinthediagnosisofthefollowingdisorders:

• Carbohydrateintolerance• Carbohydratemalabsorption• Intestinalbacterialovergrowth• Investigationofintestinaltransittime

Takingabreathtest

1. AttachabreathsamplingD-pieceandanewSteriBreath™mouthpiece.

2. Turnonthemonitorbypressingthepowerbuttononce.

3. Press .

4. If isshown,thesensorisstillstabilising.

5. Inhaleandholdbreathforthepre-set15secondcountdown,asshownonscreen.Ifunabletoholdbreathforfull15seconds,thetimercanbeadjustedinthesettings.

6. Abeepwillsoundduringthelastthreesecondsofthecountdown.

7. Blowslowlyintomouthpiece,aimingtoemptylungscompletely.

8. Theppmlevelswillriseandholdon-screen.

9. Whenthetestisfinished willappearatthebottomofthescreen.

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10. Torepeatbreathtest,press andrepeatsteps5-8.

11. Toreturntothehomescreen,press .

12. Tosavethereading,press andselecttherelevantpatientprofile.

13. RemovetheD-piecebetweenteststopurgesensorwithfreshair.

14. Toswitchoff,pressandholdthepowerbuttonfor3seconds,unitwillalsopoweroffafter45minutesofinactivitytosavepower.

Takingafacemasktest

1. Attachanewfacemasksamplingsystem.

2. Turnonthemonitorbypressingthepowerbuttononce.

3. Press .

4. If isshown,thesensorisstillstabilising.

5. Inhaleandexhaleintothefacemask,thedevicewilltakethereadinginreal-time.

6. Theppmlevelswillriseandholdatthepeaklevel,whenthishasstoppedrisingforaperiodof5consecutivesecondsthetestresultcanberecordedandtheteststopped.

7. Whenthetestisfinished willappearatthebottomofthescreen.

8. Torepeatbreathtest,press andrepeatsteps3-8.

9. Removethefacemasksamplingsystembetweenteststopurgesensorwithfreshair.

10. Toswitchoff,pressandholdthepowerbuttonfor3seconds,unitwillalsopoweroffafter45minutesofinactivitytosavepower.

AddingapatientprofileTheGastro+™Gastrolyzer®allowsup to10patientprofiles tobe set-upon thedevice inorder torecord readings toa specificpatientprofileand thendownloaded laterusingGastroCHART™.Thiscanbedonebyfollowingthestepsbelow:

1. Press onthemainscreen.

2. Pressapatientprofileslot togototheeditscreen.

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3. Press the patient profile slot again to enter the name for thepatientusingthekeyboardprovided.

4. OnceyouarehappywiththenameorID,press .

5. Youhavenowsuccessfullyset-upapatientprofile;morecanbeset-upbypressing toreturntothepatientprofilesscreenandrepeatingsteps2-4.

6. Alternativelyyoucanreturntothehomescreenbypressing .ConductingAutomaticPatientBreathTestsWarning:EnsurebatteriesarefullordeviceisconnectedtocomputerUSBport(itwillbepoweredby theUSB). If the device loses power during the automatic testingmode only saved resultswillremainonthedeviceandtheprotocoltimingswillbelost.The Gastro+™ Gastrolyzer® allows you to set up automatic testing for up to 10 patients in onesession,whichcanbeverytime-savinginabusyclinic.Thiscanbedonebyfollowingthesesteps:

1. Press onthemainscreen;thiswilltakeyoutothepatientdatabasescreenwhereyoucanselectpatientsthathavebeenpreviouslyadded.Toaddpatientsfollowsinstructionsin‘Addingapatientprofile’sectionofthismanual.

2. Hereyoucan selectup to10patients to test simplybypressing theirnameslot. Selected

patientswillchangefrompinktogreenwhenselected,todeselectthempressthenameslotagainanditwillreturntopink.

3. Oncethedesiredpatientshavebeenselected,press at thebottomofthescreentoprogresstotheprotocolscreen.

4. Hereyouareaskedtoselecttheprotocolyouwishtouseforeachpatient;theirnamewill

beshownat the topof thescreen.Select theprotocolbypressing theprotocolname, forexample ‘Lactose’, when selected the protocol will change to green. To edit the protocoltimingspleasesee‘EdittestingProtocols’sectionofthismanual.

5. Press atthebottomofthescreentoprogresstothenextpatient.

6. Whenthefinalprotocolhasbeenselectedandwhenselectingapatientduringtesting,you

willbepresentedbythreeoptions forthefirstpatient.Theirnamewillbeshownatthetopofthescreen.

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7. Toperformabreathtest(pleasenote. Ifthis isthebasesamplenosubstrate/sugarshould

begiventopatientbeforethispoint)press andfollowsteps4-8ofthe‘TakingaBreathtest’sectionofthismanual.

8. Toperformafacemasktest(pleasenote.Ifthisisthebasesamplenosubstrate/sugarshould

be given to patient before this point) press and follow steps 3-6 of the ‘Taking aFacemasktest’sectionofthismanual.

9. If thetest isunsuccessful inanywayyoucantakethetestagainbypressing ontheresultscreen,thiswilloverwritethepreviousresult.

10. Onceyouaresatisfiedwiththeresultyoucansavethistothepatientprofilebypressingthe

.

11. Ifthisisthebasesample,onceyouhavesavedtheresultyouwillbepromptedtogivethe

patienttherelevantsubstrate/sugar.Oncetheyhavedonethispress tocontinuewiththenextpatient,thiswillalsostartthenextbreathtesttimerforthepreviouspatient.

12. Youwillthenbepromptedtotestthenextpatientinthesameway.

13. When the finalpatienthasprovideda sampleand taken the substrate/sugara screenwill

showall thepatients in the testingsessionwithcountdowntimings foreachpatientuntiltheirnexttest.

14. When the timer for apatient reaches zero, analarmwill sound indicating thenext test is

readytobetakenandthepatientnamewillturngreen.

15. Takethenextreadingforthatpatientbypressingtheirnameandfollowingsteps6-10.

16. Once each patient has finished their testing protocol, their name slotwill turn green andtheirreadingswillbesavedintheirprofile.

17. You can see howmany tests have been performed and howmany are left for any given

patientbyselectingtheirnameinthesessionscreenandreferring .

18. Ifyouaresatisfiedwiththeresultsbeforetheprotocolsessionhasfinishedyoucanendthe

sessionearlybyselectingtheirnameinthesessionscreenandpressing .Youwillbeasked

toconfirmtheactionbypressing againinthenextscreen.

19. Once thecompletepatient sessionhas finishedallnameslotswill showasgreenandyou

canreturntothepatientprofilesscreeninordertoviewresultsbypressing .

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20. Results can be downloaded to GastroCHART™ for future reference or printing, followinstructionsin‘GastroCHART™Software’sectionofthismanual.

ProtocolPre-setTimingsTheGastro+™Gastrolyzer®ispre-setwithtestingprotocolsthatfollowtimeintervalsrecommendedbyclinicalresearch.Theseareshownbelow:

Test Dosage TestFrequency(minutes) Samples

Lactose3 25gofLactosein250mlofwater 0,15,30,60,90,120 6

Lactulose2 10gofLactulosein200mlofwater 0,20,40,60,80,100,120,140,160,180 10

Fructose3 25gofFructosein250mlofwater 0,15,30,60,90,120 6

Sorbitol3 12.5gofSorbitolin250mlofwater 0,15,30,60,90,120 6

Xylitol3 25gofXylitolin250mlofwater 0,15,30,60,90,120 6

Glucose3 50gofglucosein250mlofwater 0,15,30,45,60 5

EditProtocolTimingsThetestingprotocolstimingscanbeeditedwithdifferenttimingsbyfollowingthesesteps:

1. Press onthemainscreen.

2. Pressthe .

3. Selecttheprotocoltobechanged;thiswillchangetogreenwhenselected.

4. Press .

5. Selectupto10timeintervalsbypressingtheintervalslotandincreasing/decreasingthe

timingbypressing or .Thebasesamplecannotbechangedandwillshowas‘Base’,activeintervalswillshowingreen.

6. Onceyouhavefinishededitingtheprotocolpress tosave,youwillthengobacktothesettingsscreen.

EditProtocolNamesThetestingprotocolnamescanbeeditedbyfollowingthesesteps:

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1. Press onthemainscreen.

2. Pressthe .

3. Selecttheprotocoltobechanged;thiswillchangetogreenwhenselected.

4. Press .

5. Presstheprotocolnameatthetopofthescreenforexample .

6. Entertheneworpreferredprotocolnameusingthekeyboardprovided.

7. Press tosave;youwillthengobacktothepreviousscreen.

ProtocolPre-setThresholdsBelowisaninterpretationtableforgeneralguidanceoninterpretingtheH2valuesforsupportingadiagnosisofconditions.Otherfactorsthroughqualified judgementneedtobetaken inaccountbylooking at the patient history, ongoing symptoms and symptoms during test. H2 readings can beinterpreted as positive or negative using the following pre-set thresholds (this is the increase inreadingcomparedtothebasesample):

Test PositiveInterpretation

Lactose2,3 H2>20ppmCH4>12ppmcomparedtobasesample

Lactulose4 H2&CH4>20ppmcomparedtobasesamplewithin90minutesoflactuloseingestion

Lactulose2SIBO* a)Earlyincreaseofatleast20ppmforthesumofthetwogasesb)Increase>20ppmcorrespondingtotheappearanceoflactuloseinthecolon

Lactulose2IITT** Fast>20ppmpeakisdetectedat60minutesNormal>20ppmpeakisdetectedat80minutesSlow>20ppmpeakisdetected100minutesorlater

Fructose2 H2>20ppmCH4>12ppmcomparedtobasesample

Sorbitol3 H2>20ppmcomparedtobasesample

Xylitol3 H2>20ppmcomparedtobasesample

Glucose3 H2>10ppmCH4>10ppmcomparedwithbasesample

*SIBO=SmallIntestinalBacterialOvergrowth**IITT=ImpairedIntestinalTransitTime

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EditProtocolPre-setPositiveThresholdsThepre-setthresholdscanbeeditedbyfollowingthesesteps:

1. Press onthemainscreen.

2. Pressthe .

3. Selecttheprotocoltobechanged;thiswillchangetogreenwhenselected.

4. Press .

5. Press .

6. Press or toincreaseanddecreasethethreshold.

7. Press tosave;youwillthengobacktothesettingsscreen

TechnicalSpecification

Gastro+™Gastrolyzer®ConcentrationRange(H2) 0-500ppmDisplay FullcolourtouchscreenDetectionPrinciple ElectrochemicalsensorRepeatability <10%onconsecutivereadingsCarbonMonoxideCross-sensitivity <1%Power 3xAA(LR6orEquivalent)

1xCR2032LithiumcoincellApprox.3xAABatteryLife 1,000minutesApprox.1xCR2032BatteryLife 175,000hoursT90ResponseTime ≤45secondsOperatingTemperatureRange 15-35°C(Storage/Transport0-50°C)Operating/Transport/StoragePressure 800-1200mbarOperatingHumidity 10-90%non-condensing(Storage&

Transport0%-95%)SensorOperatingLife 2yearsSensorSensitivity 1ppmSensorDrift <2%permonth

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Dimensions Approx.34x75x140mmWeight Approx.200g(includingbatteries)MonitorConstruction Case:Polycarbonate/ABSblend

SteriTouchanti-microbialadditiveD-Piece:Polypropylene

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SafetyInformationandDeviceSymbolsDegreeofprotectionagainstelectricshock TypeBFappliedpartTypeofprotectionagainstelectricshock InternallypoweredequipmentDegreeofprotectionagainstingressofliquid IPXO-notprotectedagainstwater

ingressDegreeofsafetyapplicationinthepresenceofaflammableanaestheticmixturewithair,oxygenornitrousoxide

Equipmentnotsuitableforuseinthepresenceofflammablemixtures.

RefertoManual

DirectCurrent

CEMark

TypeBFappliedpart

DisposeofaccordingtoWEEE

SerialNumber

ManufacturebyandDate

BedfontLogo

EnvironmentTheGastro+™Gastrolyzer®product

complieswiththedirectiveEN60601-1-2electromagnetic

compatibilitybutcanbeaffectedbycellularphonesandbyelectromagneticinterferenceexceedingthelevelsspecifiedinEN50082:1.Thisequipmentshouldbemovedifnecessarytoavoidinterference.

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InstrumentLayout

1. Display2. Powerbutton3. BreathsamplingD-Piece™4. D-Piece™aperture5. Exhaustportforbreathsample6. USBconnector(forusewithCOdataSoftware)7. Single-useSteriBreath™mouthpiece8. Batterycompartment119. Batterycompartmentclip10. Resetbutton11. Programmingswitch

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DisplaySymbolsDescription Gastro+™Gastrolyzer®Batterycondition:Full

Batterycondition:Low

Batterycondition:Empty

BreathTest

FacemaskTest

AutomaticPatientBreathTest

Inhale

HoldBreath

EditCountdown(breathhold)Timer

Countdown(breathhold)

Exhale

ppmReading

Save

Settings

Home

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Description Gastro+™Gastrolyzer®PatientProfiles

PatientprofileSlot

PatientResultsChart

DeletePatientRecord

TimeUntilNextBreathSample

FinishandSave

ChangeD-Piece

NextStep

PreviousStep

SensorChangeDueSoon

SensorChangeOverdue

CalibrationDueDate

CalibrateDevice

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Description Gastro+™Gastrolyzer®AttachFlowMetertoGasCanister

AttachCalibrationAdaptortoD-Piece

AttachD-PiecetoMonitorandTurnonGasFlow

SystemProcessing

CalibrationSuccessful

CalibrationFailed

RetryCalibration

3MonthCalibrationReminder

DeviceReadingHistory

EditDate/Time

FirmwareVersion

SerialNumber WarningsandMaintenance

1. SteriBreath™mouthpiecesshouldbereplacedaftereveryuse.2. Handsshouldbewashedregularlyinaccordancewithinfectioncontrolpractice.3. Pleasedonotattempttomodifytheequipmentinanywayoruseaccessoriesnotspecified

by the manufacturer. Any attempt to do so will invalidate the warranty and maycompromisethesafetyofthedevice.

4. Bedfontwillmakeavailableuponrequestservicetrainingtoappropriatelyqualifiedpersons.

V2.23SN: HG000001

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5. Holdingtheresetbuttondownfor30secondswillperformcompletedevicereset,thiswillclearanysaveddataandrevertallsettingstothefactorydefaults.Afterperformingaresetthedevicewillneedtohavethedate/timesetandbecalibratedbeforeitcanbeused.

Cleaning

1. TheGastro+™Gastrolyzer® ismouldedwith SteriTouch® technology foroptimum infectioncontrolandhasprovenbacterialprotectionefficacy.HoweverBedfont recommendwipingthe instrumentandD-pieceexternalsurfaceswithaproductspecificallydevelopedforthispurpose.Bedfontprovidesinstrumentcleaningwipes.TheD-Piececannotbesterilised.

2. NEVERusealcoholor cleaningagents containingalcoholorotherorganic solvents as longtermexposuretothesevapourswilldamagetheH2sensorinside.

3. Under no circumstances should the instrument be immersed in liquid or splashed withliquid.

ReviewinghistoryTheGastro+™Gastrolyzer®willrecordeveryreadingtakeninitshistoryupto150readings,toaccess

thispress andthen thehistorywillthenbeshown.Changingdateandtime

Press andthen youcanthenselecteitherd-m-yorm-d-yforthedateformatand12hor24hforthetimeformat.Datesandtimesarethenadjustedbyselectingthenumberyouwishto

changeandpressing or toincreaseanddecrease.Press tosaveyoursettings.RoutineMaintenance

1. Replacebatterieswhenindicatedbytheemptysymbol .2. Bedfont recommend removal of the batterieswhen the device is not used for prolonged

periodsoftimetopreventleakage. 3. Replace breath sampling D-piece every 30 days or if visibly soiled or contaminated. The

Gastro+™ will give a reminder during start-up when the D-piece should be replaced, see‘ChangeD-Piece’symbol.

4. Thedevicemustbecalibratedonceevery3monthswithaBedfontsuppliedcalibrationkitandassociatedgas,see‘Calibration’.

5. Bedfont recommend an annual service in order to check sensor and component partsperformance.

6. Thesensorshouldbereplacedeverytwoyears.

7. Themonitorwill providedaily reminders, via the reminder screen , after turningontheGastro+™for2monthsleadinguptothesensorchangeduedate.

8. Additionaltechnical informationcanbemadeavailableonrequest;pleasecontactBedfontoritsdistributor.

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CalibrationThe Gastro+™ Gastrolyzer® is calibrated at 21°C (±4°C) before leaving Bedfont. The instrumentshouldbe calibratedat21°C (±4°C)as this is the temperatureatwhichwe recommend it is tobeused.TheGastro+™Gastrolyzer®shouldbecalibratedeverythreemonthsandwillgiveareminderduringstart-upwhencalibrationisdue.Thecalibrationgasrequiredis100ppmhydrogeninair.

1. Turnonthemonitorbypressingthepowerbuttononce.

2. Press .

3. Startthecalibrationprocessbypressing .

4. Firstthemonitormustbezeroedandthiswillhappenautomatically,showingthissymbol oncethecalibrationprocesshasstarted,donotconnectgasatthisstage.

5. Once thishasbeensuccessfully carriedout the first stepof thecalibrationprocesswillbe

shownonscreen.Followtheonscreeninstructionstofinishthecalibrationprocess.

6. Gasflowshouldbesetto0.5litresperminute.

7. Asuccessfulcalibrationwillbeindicatedbythe ,press toreturntothehomescreen.

8. Afailedcalibrationwillbe indicatedby ,press toattemptcalibrationagain. If theproblempersistssee‘Troubleshooting’orcallyourlocalsupplierofBedfontproducts.

9. Returntothehomescreenbypressing .

TroubleshootingIftheunitfailstoturnonproperly,iftheloworemptybatterysymbolsareshown, or ,replacethebatteries.Ensurethatthebatteriesare insertedthecorrectwayaround,matchingthesymbolsmouldedintotheplastic.GastroCHART™Software–ConnectingtothePCPlaceoneendoftheconnectionleadintotheUSBsocketonthetopoftheGastro+™Gastrolyzer®,connectingtheotherendtotheUSBportonthePC.Beforestartingthesoftware,ensurethattheGastro+™Gastrolyzer®isconnectedtothePCandswitchedon.DoubleclicktheGastroCHART™iconon the PC to start the programme. Refer to the supplied documentation for how to operateGastroCHART™.(GastroCHART™availabletodownloadforFREEatwww.bedfont.com)ReturnsProcedure

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If your equipment requires servicing, please contact your local Bedfont Customer ServiceDepartment,distributororsupplierbeforereturninganygoods.

1. WhenyouhavesuppliedtheCustomerRepairsDepartmentwiththemonitorserialnumberanddescriptionof the fault,youwillbe issuedwitha returns/ ticketnumber.Pleasestatethe returns/ticket number on the outside of the box when returning the monitor, andensurethatyourfulldetails,telephone,faxnumbersandreturnaddressareclearlystated.

2. The product must also be decontaminated before it is returned according to your localregulations.Bedfontcanprovideyouwithadecontaminationcertificatetocomplete,whichalsoneedstobeattachedtotheoutsideofthebox.FailuretodosowillresultintheproductbeingsubjecttoBedfontdecontaminationprocedureandwilldelayyourservice/repairandmayincurcoststoyourself.

3. Bedfontadvisethatyouuseacourierservicewhenreturningmonitors.Thisenablesyoutoinsuregoodsfor lossordamageintransit.Whenyourgoodsarereceived,youwillbesentanemailstatingso.

4. Ifthedevicehasbeenreturnedforrepair itwillthenbeexaminedandyouwillbesentan‘Engineer’sReport’andaquotationfortherepair,whichwillincludeanauthorisationform.Completetheauthorisationform,andensurethatyou includethe ‘OfficialPurchaseOrderNumber’.Pleasecontact theCustomerRepairsDepartment if youareunable to supplyan‘OfficialPurchaseOrderNumber’.

5. If your monitor is still in warranty and the fault is covered by warranty, see ‘Warranty’sectionofthismanual,Bedfontwillrepairitandreturnittoyouwithan‘Engineer’sReport’,freeofcharge.

6. Ifyouchoosenottoproceedwiththerepair,ahandlingfeewillbecharged.Ensurethatyoureturnthecompletedauthorisationformwithan‘OfficialPurchaseOrderNumber’.

7. The equipment will be returned to you as soon as Bedfont has received all relevantpaperwork.Acarriagefeewillbechargedifthemonitorisnolongerinwarranty.

SparesD-PIECE-2 Boxof12D-Pieces(non-sterile)STERIBREATH Boxof250SteriBreathMouthpieces(non-sterile)012-14-12010K-V 12Litre100ppmCalibrationKit012-14-12010-V 12Litre100ppmReplacementCalibrationCanister034-14-12010K-V 34Litre100ppmCalibrationKit034-14-12010-V 34Litre100ppmReplacementCalibrationCanisterWIPE-V Packof50CleaningWipesBAT017 AABatteryFXS397 USBCableWarrantyBedfont Scientific Limitedwarrants theGastro+™Gastrolyzer®product (excludingbatteries andH2

sensor)tobefreeofdefectsinmaterialsandworkmanshipforaperiodoftwoyearsfromthedateof shipment. The H2 sensor is warranted for 12 months. Bedfont’s sole obligation under thiswarranty is limited to repairing or replacing, at its choice, any item covered under this warrantywhen such an item is returned, intact and prepaid, to Bedfont Scientific Limited or the localrepresentative.

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Thiswarrantyisautomaticallyinvalidatediftheproductsarerepaired;altered,voidlabelsremovedorotherwisetamperedwithbyunauthorisedpersonnel,orhavebeensubjecttomisuse,neglectoraccident.Never dispose of any electronic instrument or batteries in domestic waste. At the end of theproduct’slife,contactBedfontoritsdistributorfordisposalinstructions.Single use consumables and accessories should be disposed of in line with local clinical wasteguidelines.References

1. Levitt,M.D.(1969):Productionandexcretionofhydrogengasinman.NewEngl.J.Med.281:122-127

2. BiolabMedicalUnit;NutritionalandEnvironmentalMedicine;LondonEngland.BreathHydrogenandMethaneFebruary2012.Availableathttp://www.biolab.co.uk/docs/bhydro.pdf

3. LedochowskiM.LedochowskiE.HydrogenBreathTests2008;AvailablefromBedfontScientificLtd

4. PimentalM.etalMethaneProductionduringLactuloseBreathTestisAssociatedwithGastrointestinalDiseasePresentation.DigestiveDiseasesandSciences.Vol.48No.12003

Station Road, Harrietsham, Maidstone, Kent, ME17 1JA EnglandTel: +44 (0)1622 851122 Fax: +44 (0)1622 854860 Email: [email protected] www.bedfont.com

Issue 3- August 2016, Part No: LAB678 Bedfont Scientific Limited reserves the right to change or update this literature without prior notice.Registered in: England and Wales. Registered No: 1289798

© Bedfont Scientific Limited 2016

Contact Bedfont or one of our worldwide Gastrolyzer® distributors for a free demonstration

www.bedfont.comTel:+44 (0)1622 851122

Email: [email protected]

A full list of our worldwide distributors can be found at http://www.bedfont.com/uk/english/distributors

Scientific contributions to health.