Slide 1Heterochromatin silencing at p53 target genes by a small viral protein. Slide 2 p53  Revealed character as a tumor suppressor gene in 1989.  Tumor suppressor…

Slide 1NF2/Merlin and Neurofibromatosis 2 March 25, 2003 By: Caroline Clendenin Slide 2 Neurofibromatosis: An Overview NF is the most common neurological disorder caused…

Slide 1 Cancer Etiology 1. Introduction 2. Chemical Factors in Carcinogenesis 3. Physical Factors in Carcinogenesis 4. Viral Oncogenesis 5. Genetic Predisposition 邵吉民，教授，病理学与病理生理学系…

Slide 1Notes - Cancer and Cell Division FACT: Each minute your body needs to make about 300 MILLION NEW CELLS! Slide 2 I. Why Do Cells Divide? A cell spends a good part of…

Slide 1 A few thoughts on cancer and cancer family syndromes Pamela McGrann, MD. Department of Medical Genetics Slide 2 Family cancer syndromes Family cancer syndromes There…

Slide 1 Chapter 8 Cancer Genetics Slide 2 Introduction Chromosomal changes in cancer cells were recognized early in the 20th century, and it was later found that environmental…

Slide 1 Immunity to tumors Tumor antigens Immune system’s reaction to tumor antigens How tumors evade the immune system Immunologic approaches to treatment of cancer Slide…

Slide 1 Smad4 (DPC4) A tumor suppressor gene Slide 2 Smad4 (DPC4) Smad4: Mothers against decapentaplegic (dpp) homolog 4Smad4: Mothers against decapentaplegic (dpp) homolog…

Slide 1 Opener A “Smart Drug” Slide 2 Figure 17.1 One Gene, One Enzyme (Part 1) Slide 3 Figure 17.1 One Gene, One Enzyme (Part 2) Slide 4 Figure 17.2 Hemoglobin Polymorphism…

Slide 1 Cancer II Slide 2 Six ways of losing the remaining good copy of a tumor suppressor gene Slide 3 When proto-oncogene becomes overactive it becomes an oncogene Slide…