Slide 1SHINING A LIGHT ON THE GENOME’S ‘DARK MATTER’ NON-CODING RNAs (nc RNAs) : MICRORNAs AND CANCER SHINING A LIGHT ON THE GENOME’S ‘DARK MATTER’ NON-CODING…

Slide 1Trends in Biotechnology Revision Questions Slide 2 In 2005, ES-like cells were generated using four factors. The resulting cells were called iPS cells. What does iPS…

Slide 1 Concepts of Neoplasia OBJECTIVES/RATIONALE A neoplasm is an abnormal growth of tissue that may be benign or malignant. The student will identify terms related to…

Slide 1 The Story of Bcl-2 Linking cell apoptosis to tumor metastasis Crystal structure of Bcl-2 complex By Yaming Wang Slide 2 History Bcl-2 was first isolated in B Cell…

Slide 1 Ras and Cancer Back to where we began: Protein structure combining Bioinformatics, protein structure with Kinemage, and the Map kinase path page 776-780 Slide 2 Ras…

Slide 1 Cancer II Slide 2 Six ways of losing the remaining good copy of a tumor suppressor gene Slide 3 When proto-oncogene becomes overactive it becomes an oncogene Slide…

Slide 1 Generation of Oncogenes The major ways of generating oncogenes: Proliferation stimulating gene acquired by a virus. Proviral insertional mutagenesis places growth…

Slide 1 i=1,2,...N data points = vertices of graph neighbors i,j connected by edges 5 1 8 J i,j – weight associated with edge i,j J 5,8 J i,j depends on distance D i,j…

Slide 1 Slide 2 Cancer and the Immune System Amar Bhatt Shirley Masand Jaime Warmkessel Immunology Chapter 22 April 22, 2003 Slide 3 A Look Ahead Tumors and Metastasis Oncogenes…

Slide 1 Molecular Biology of Cancer What are the environmental influences that are cancer-causing? What is the difference between an oncogene and a proto-oncogene? What genetic…