Slide 1Bioinformatics & Algorithmics. www.stats.ox.ac.uk/hein/lectures. Strings. Trees. Trees & Recombination. Structures: RNA. A Mad Algorithm Open Problems. Questions…

Slide 1 Finding Orthologous Groups René van der Heijden Slide 2 What is this lecture about? What is ‘orthology’? Why do we study gene-ancestry/gene-trees (phylogenies)?…

Slide 1 FOG: High-Resolution Fungal Orthologous Groups René van der Heijden Project 5.10: Comparative genomics for the prediction of protein function and pathways in Saccharomyces…

Slide 1 My wish for the project-examination It is expected to be 3 days worth of work. You will be given this in week 8 I would expect 7-10 pages You will be given 2-4 key…

Terminal node (terminal) (=interior branch) Outgroups Most Recent Common Ancestor of B+C MRCA of A+B+C MRCA of N+A+B+C âbasalâ to the ingroup Monophyly (monophyletic) Paraphyly…

Phylogenetic Inference Involves an attempt to estimate the evolutionary history of a collection of organisms (taxa) or a family of genes Two major components Estimation of…