Slide 1 Extra office hours:Thurs, Feb 8 11am-12 Fri, Feb 9 2-4pm I WILL NOT BE HOLDING OFFICE HOURS ON TUESDAY Feb 13!! Dina, Tim, and I encourage all confused students to…

Slide 1 Antigen presentation in a nutshell Slide 2 ANTIGEN-SPECIFIC T – CELL ACTIVATION PARTNERS Antigen presenting cell carrying antigenic peptides bound to MHC – pre-formed…

ANTIGEN-SPECIFIC T – CELL ACTIVATION PARTNERS Antigen presenting cell carrying antigenic peptides bound to MHC – pre-formed MHC – peptide complexes Self MHC with captured…

MOLECULES, CELLS AND DISEASE – Introduction to cells Lecture 1: Introduction to immunology 1) Explain the importance of immunology for human health 2) Outline the basic…

Engagement of the TCR causes an early rise in [Ca2+]i Negulescu et al, 1996 The [Ca2+]i rise is necessary for T cell activation I. Pharmacological evidence Chung et al, 1994…