Slide 1Figure 1. Characterization of Human U2OS 2- 6-3 Cells(A) Schematic representation of the gene expression plasmid, p3216PECMS2. The plasmid is composed of 256 copies…

Slide 1Protein Folding and Processing  The classic principle of protein folding is that all the information required for a protein to adopt the correct three-dimensional…

Slide 1Transcriptome Profiling of Human Cardiac Tissues in Hypoplastic Left Heart Syndrome Karl D. Stamm, MS Donna K. Mahnke, MS; Mary A. Goetsch, MS; D. Woodrow Benson,…

Slide 1 Molecular Chaperones The Hsp70 Super-family Slide 2 Pathways For Protein Folding Slide 3 Protein Folding in Cells Occurs in a Crowded Environment where Misfolding…

Slide 1 Bio 402/502 Section II, Lecture 5 mRNA export, RNA surveillance, and Transport of proteins in and out of the nucleus Dr. Michael C. Yu Slide 2 mRNA export - formation…

Slide 1 Mural at NASA Ames Research Center Homing Endonucleases Slide 2 Sequence nearly identical to the carrot vma1 gene – except for central region of about 1200 nucleotides.…

Slide 1 1 Mutations and the code Frameshift mutations A single base-pair deletion or insertion results in a change in the reading frame AUG UUU AGC UUU AGC UUU AGCWT Met…

Nonsense-Mediated mRNA Decay (NMD) Nonsense mediated decay of mRNAs. The monitoring of mRNAs for premature termination codons (PTCs) is mediated by ribosomes during the “pioneering…

Simplify the display Show only alpha carbons Turn off show backbone oxygen Colour secondary structure Turn 3 D display on 1HEW Backbone as alpha carbons Sidechains only Tyr62…

Mural at NASA Ames Research Center Homing Endonucleases Sequence nearly identical to the carrot vma1 gene â except for central region of about 1200 nucleotides. Homing Self…