Pathology CELLULAR AGEING 1 Ageing: âProgressive time related loss of structural and functional capacity of cells leading to deathâ Senescence, Senility, Senile changes.…

Slide 1 Molecular Biology of CML Overview: Research into chronic myeloid leukemia (CML) over the last 40 years has lent insight into the role of altered cellular biochemistry…

RNA INTERFERENCE Accidental Discovery Nobel Prize for Medicine-2006 Fire and Mello mex-3, highly expressed in C. elegans embryos RNA Interference The phenomenon where double…

Epigenetics Heritable characteristics of the genome other than the DNA sequence Heritable during cell-division (mitosis) To a lesser extent also over generations (meiosis)…

1. RNA Interference (RNAi) Ryan DuvalEndodontics 2. Discovery of RNAi First observed in petunias Napoli et al 1990 Observed “cosuppression” Occurring at post-transcriptional…

RNA INTERFERENCE Accidental Discovery Nobel Prize for Medicine-2006 Fire and Mello mex-3, highly expressed in C. elegans embryos RNA Interference The phenomenon where double…