Slide 1 Initiation of rDNA transcription Two transcription factors, UBF and SL1, bind cooperatively to the rDNA promoter and recruit RNA polymerase I to form an initiation…
Slide 1 Three types of RNA polymerase in eukaryotic nuclei TypeLocationRNA synthesizedEffect of -amanitin INucleolusPre-rRNA for 18, 5.8 and 28S rRNAsInsensitive IINucleoplasmPre-mRNA,…
Slide 1 RNA processing #1 Making ends of RNA Slide 2 Types of RNA processing A) Cutting and trimming to generate ends: –rRNA, tRNA and mRNA B) Covalent modification: –Add…
Chapter 14: The Mechanism of Translation We can do experiments on rRNAs today that are far more powerful than anything we ever attempted with ribosomal proteins in the past.…
MATISSE - Modular Analysis for Topology of Interactions and Similarity SEts http://acgt.cs.tau.ac.il/matisse Igor Ulitsky and Ron Shamir Identification of Functional Modules…