Organization of DNA • DNA reassociation kinetics – Allow DNA for a given species to denature (usually by heat) – Time how long it takes for the DNA to renature –…

Slide 1Repetitive elements Significance Evolutionary signposts Passive markers for mutation assays Actively reorganise gene organisation by creating, shuffling or modifying…

1.Definition• Biotechnology is theintegration of naturalscience and organisms,cells, parts thereof andmolecular analogues forproducts and services.2. Oldest form of biotechnology…

1.Thomas Keane, WTSI 14th May, 2011 Assessing the impact of transposable element variation on mouse phenotypes and traits Thomas Keane Vertebrate Resequencing Informatics…

1.Molecular Genetics Part II From Gene to Protein2. HistoryArchibald Garrod – 1909 First to suggest that genes dictate phenotype through production of proteins Believed…

1.Molecular Genetics Part II From Gene to Protein2. History• Archibald Garrod – 1909• First to suggest that genes dictatephenotype through production ofproteins•…

1.TransposonsImage courtesy of Lauren Solomon, Broad Communications The reddish streaks on these corn grains are caused by transposons. Submitted to:Zaahir Salam Dr. S.Kannan2.…

Slide 1Chap. 6 Problem 2 Protein coding genes are grouped into the classes known as solitary (single) genes, and duplicated or diverged genes in gene families (Table 6.1).…

Slide 1 Retroviruses and Retroposons Chapter 22 Slide 2 2 22.1 Introduction Figure 22.1 Slide 3 3 22.2 The Retrovirus Life Cycle Involves Transposition-Like Events A retrovirus…

Slide 1 31 Gene regulation in bacteria Slide 2 Lecture Outline 11/18/05 Finish up from last time: Transposable elements (“jumping genes”) Gene Regulation in Bacteria…