Carcinogenesis Characteristics of Cancer Disorder of altered cell differentiation and growth  Results in neoplasia (“new growth”) Growth is uncoordinated and relatively…

1. WELCOME 2. Cell cycle and its checkpoints 2 PRESENTED BY: MISS SAYANTI SAU I M. PHARM DEPT. OF PHARMACOLOGY PESCP, BANGALORE FACILIATED TO: Mr. Mukund handral Asst. professor…

Slide 1Lecture 25. Transformation and Oncogenesis. Flint et al, Chapter 18 Cancer: a genetic disease Results from growth of successive populations of cells in which mutations…

Slide 1 Biological Gene and Protein Networks Xin Zhang Department of Computer Science and Engineering Slide 2 Biological Networks  Gene regulatory network: two genes are…

Slide 1 Chapter 18 PART IV: Molecular Pathology of Human Disease Molecular Basis of Pulmonary Disease Companion site for Molecular Pathology Author: William B. Coleman and…

Slide 1 Types of Carcinogens Clinical aspects of neoplasia Paraneoplastic syndromes Grading & staging Slide 2 Carcinogens cause genetic damage and induce neoplastic transformation…

23.1 Cancer Is a Group of Diseases Characterized by Cell Proliferation Tumor Formation: A Distinct Mass of Abnormal Cells Benign tumor: the tumor remains localized. Malignant…

There are intracellular and extra cellular signals that control the cell cycle and apoptosis. * * Intracellular Controls Intracellular controls may either be “negative”…

HALLMARKS OF CANCER - Together dictate the malignant phenotype. 1. Self-sufficiency in growth signals 2. Insensitivity to growth inhibitory signals 3. Evasion of cell death…

Chap. 19 Problem 1 Passage through the cell cycle is unidirectional and irreversible due to the degradation of critical regulators by proteasome complexes at specific points…