1. Sci Transl Med 3, 111ra121 (2011); DOI: 10.1126/scitranslmed.3003161 Raunak Shrestha 30th October 2012 1 2. • Pair-end Whole Genome Sequencing (5X – 15 X) • Targeted…
Sensitivity and resistance profiles over 240 cell lines Resistant Sensitive IC 50 GI50 PLX-4032 analog (BRAF inhibitor) PD0325901 (MEK inhibitor) Sorafenib (RAF, PDGFR, cKIT,…