Slide 1DNA nucleus double helix cytoplasm Base pairs copy gene amino acid protein A,G,C,T Ribosome Write the ledger for this diagram – include these words Slide 2 Learning…

p53 and Cancer Karina Espinoza Biochemistry 118Q What is p53? What is p53?  A protein found inside cells  A stress sensor of signals: -DNA damage -hypoxia -oncogene…

Slide 1p53 The Master Guardian of the Genome Slide 2 p53 gene mutations in human tumors Greenblatt et al. (1995) Cancer Res. 54:4855 50% Slide 3 p53 (low) p53 (high) Cell…

Slide 1 Computational Systems Biology Prepared by: Rhia Trogo Rafael Cabredo Levi Jones Monteverde Slide 2 What are Biological Systems? Popular Notion: It is a complex system…

Slide 1 Slide 2 Cell Cycle, Cancer, and the Biology Student Workbench An intro to what BSW can do 2002 Steve Moore & Kathy Gabric Slide 3 p53 p53 is a tumor suppressor…

p53 Mutant Mice with Altered Cancer and Aging Phenotypes Larry Donehower Baylor College of Medicine Houston, Texas 77030 p53 - A Major Node in the Cellular Stress Response…