Metabolism of purine nucleotides A- De Novo synthesis: of AMP and GMP Sources of the atoms in purine ring: N1: derived from NH2 group of aspartate C2 and C8: from formate…
Metabolism of purine nucleotides 1- Biosynthesis of purine nucleoetides A- De novo biosynthesis (10 % in liver mainly) B- Salvage pathway (90 % in other tissues) 2- Degradation…