1. Pan-genomics: theory & practice Michael Schatz Sept 20, 2014 GRC Assembly Workshop #gi2014 / @mike_schatz 2. Part 1:Theory 3. Advances in Assembly! First PacBio RS…

BLAST- Basic Local Alignment Search Tool · Similarity search program developed at NCBI · Available as free service over the Internet · Provides very fast, accurate,…

Slide 1The genome of prokaryotes and eukaryotes- nuclear and extranuclear genetic organization Slide 2 Genomics, Genetics and Biochemistry Genetics: study of inherited phenotypes.…

Slide 1 Please feel free to chat amongst yourselves until we begin at the top of the hour. 1 Slide 2 Seminar Agenda The Reproductive System Questions & Answers 2 Slide…

Slide 1 Protein Targeting by Functional Linkage of Non-Homologous Proteins with examples from M. tuberculosis Genome-wide functional linkage map Structural Genomics of Complexes:…

Slide 1 1 (c) Mark Gerstein, 1999, Yale, bioinfo.mbb.yale.edu BIOINFORMATICS Databases Mark Gerstein, Yale University bioinfo.mbb.yale.edu/mbb452a Slide 2 2 (c) Mark Gerstein,…

Slide 1 Sequence and structure databanks can be divided into many different categories. One of the most important is Supervised databanks with gatekeeper. Examples: Swissprot…

Slide 1 Description of Group B Streptococcus Pan-genome Genome comparisons of 8 closely related GBS strains Tettelin, Fraser et al., PNAS 2005 Sep 27;102(39) Slide 2 Method…

Slide 1 Analyses of ORFans in microbial and viral genomes Journal club presentation on Mar. 14 Albert Yu Slide 2 ORFan Defenition: an ORF with no detectable sequence similarity…

Slide 1 Scale of the ‘unknown’ gene problem Scale of the ‘unknown’ gene problem Principles of comparative genomics Shared plant-prokaryote genes Shared plant-prokaryote…