Using Genomics in the Design of Phase III Clinical Trials Richard Simon, D.Sc. Chief, Biometric Research Branch National Cancer Institute http://linus.nci.nih.gov Nothing…

Validation of Predictive Classifiers Richard Simon, D.Sc. Chief, Biometric Research Branch National Cancer Institute http://linus.nci.nih.gov/brb Biomarker =Biological Measurement…

Developing Predictive Classifiers and their Use in the Design of Pivotal Clinical Trials Richard Simon, D.Sc. Chief, Biometric Research Branch National Cancer Institute http://linus.nci.nih.gov/brb…

New Approaches to Clinical Trial Design Development of New Drugs & Predictive Biomarkers Richard Simon, D.Sc. Chief, Biometric Research Branch National Cancer Institute…

New Approaches to Clinical Trial Design Development of New Drugs & Predictive Biomarkers Richard Simon, D.Sc. Chief, Biometric Research Branch National Cancer Institute…

Using Predictive Classifiers in the Design of Phase III Clinical Trials Richard Simon, D.Sc. Chief, Biometric Research Branch National Cancer Institute http://linus.nci.nih.gov/brb…

Targeted (Enrichment) Design Prospective Co-Development of Drugs and Companion Diagnostics Develop a completely specified genomic classifier of the patients likely to benefit…

When is Small Beautiful? Richard Simon, D.Sc. Chief, Biometric Research Branch National Cancer Institute http://brb.nci.nih.gov For Demonstrating a Large Treatment Effect…

Using Predictive Classifiers in the Design of Phase III Clinical Trials Richard Simon, D.Sc. Chief, Biometric Research Branch National Cancer Institute http://linus.nci.nih.gov/brb…