Slide 1Microarray and functional genomics Wenjing Tao University of Missouri Slide 2 Microarray: high through-put whole genome approach Microarray is a tool for analyzing…

Slide 1 Slide 2 SNARE complex and Ca 2+ sensor Slide 3 Endocytic invagination 1.Bar-domain containing protein such as amphiphysin which inducing membrane curvature 2.Clathrin,…

Page 1 1 Le nucléosome ADN et chromosome Page 2 2 Solomon,D 2004, Nat cell Biol : Heterochromatic domains in a mouse nucleus Dimethylated Lys 9 of Histone H3 is shown in…

Présentation PowerPoint Clotilde Théry, PhD, team « Exosomes and tumor growth » Institut Curie, INSERM U932, « Immunity and Cancer », Paris Molecular mechanisms…

Slide 1 Techniques for synaptic vesicle recycling 1.Electrophysiology 2.Imaging 3.Electron microscopy FM dyes SynaptopHluorin Quantum dots Slide 2 Sankaranarayanan et al,…

Slide 1 Multiple Wnt Signaling Pathways Converge to Orient the Mitotic Spindle in Early C. elegans Embryos Walston T. et al. Developmental Cell, Vol. 7, 831–841, December,…

Uromodulin and kidney disease: a new entry for an old molecule MCKD/FJHN Italian Consortium Gian Marco Ghiggeri Lyon ESPN 2008 Uromodulin Most abundant protein in human urine…

Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment Schafer ZT, Grassian AR, Song L, Jiang Z, Gerhart-Hines Z, Irie HY, Gao S, Puigserver…

Mechanisms? Mechanisms? How does actomyosin contractility influences gene transcription? 1 de Lanerolle & Serebryannyy (2011) Nat Cell Biol 13: 1282-1288 a) Pol II -…

Holinger JBC 274, 13298-304, 1999 Stapled alpha-helix of BCL-2 domains (SAHB) Walensky Science 305, 1466-70, 2004 Proposed mechanism of bcl-2 pore formation Gottlob et al.,…