1. Dr. Alan Teh , 2012 2. Sarah Newbury, the first reported patient with multiple myeloma. A) Bone destruction in the sternum. (B) The patient with fractured femurs and right…

Slide 1Electrophoresis and its Application for diagnosis Ratchada Cressey, PhD Clin. Chem 202 Slide 2 Principal of electrophoresis Electrophoresis is the process of moving…

1. Paraproteinemia John Matthews 2. Definition of a paraprotein Amonoclonalimmunoglobulin or immunoglobulin light chain in the blood or urine resulting from a clonal proliferation…

1. What is the diagnosis? 2. • Second most common (10-15% of all) hematological cancer. • Responsible for 15-20% of deaths from hematological cancer and about 2% of all…

Approach to Patients with Monoclonal Immunoglobulin Disorders Approach to Patients with Monoclonal Immunoglobulin Disorders Ig abnormalities can be classified as one of three…

Slide 1 Hyperimmunoglobulinemia Abnormally high blood levels of immunoglobulins. Abnormally high blood levels of immunoglobulins. Polyclonal immunoglobulins Polyclonal immunoglobulins…

Slide 1 Multiple myeloma (MM) The second most common adult haematological malignancy. MM is a clonal malignancy of terminally differentiated plasma cells. Slide 2 Multiple…

Multiple myeloma (MM) The second most common adult haematological malignancy. MM is a clonal malignancy of terminally differentiated plasma cells. Multiple myeloma: Epidemiology…

Abstract Plasma cell dyscrasias, most commonly associated with paraproteinemia, are a diverse group of diseases. Monoclonal gammopathy of undefined significance (MGUS) can…

Multiple myeloma (MM) The second most common adult haematological malignancy. MM is a clonal malignancy of terminally differentiated plasma cells. Multiple myeloma: Epidemiology…