Eular On-line Course on Rheumatic Diseases – module n°5 Prof. Tore K Kvien, Dr. Hans Ulrich Scherer and Prof. Gerd-Rüdiger Burmester PATHOGENESIS AND CLINICAL ASPECTS…

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1. Dr. Suhail Qureshi Monoclonal Antibodies 2. Journey so far…  1st generation of MAbs : limited effectiveness in trials  Concerns : Imunogenicity & inefficient…

1. Is Ofatumumab Better than Rituximab? Ofatumumab is a fully human antibody produced in transgenic mice immunized with CD20 • UK-based GlaxoSmithKline and Danish biotech…

Application Note Background Macrophages are tissue-resident profes- sional phagocytes and antigen-presen- ting cells (APC), which differentiate from circulating peripheral…

Toxicity and Monitoring of Immunosuppressive Therapy Used in Systemic Autoimmune However, other agents may be more effective in achieving remission and stability of the disease…

Slide 1Sea Urchin Genome Slide 2 Origin The sea urchins (Class Echinoidea) are one of five extant classes within the phylum Echinodermata. S. purpuratus belongs to a complex…

Slide 1 02.21.11 Lecture 14 - The cell cycle and cell death Slide 2 The cell cycle: cells duplicate their contents and divide Slide 3 The cell cycle may be divided into 4…

Slide 1 Monoclonal antibodies Anticancer therapy Weihua Wu Slide 2 What is an antibody? An antibody is a protein used by the immune system to identify and neutralize foreign…

Anti-viral Immunity Distinct features of viruses Viruses are intracellular pathogens Viruses cause changes in infected cells. Infected cells bear stress signals. These changes…