1. Central Dogma Information storage in molecules DNA RNA Protein transcription translation replication 2. Proteins Carbon-Nitrogen backbone amino acid side chains 3. The…

Slide 1Scoring Matrices Slide 2 Slide 3 Limitations to Needleman-Wunsch The problem with Needleman-Wunsch is the amount of processor memory resources it requires. Because…

1.Inleiding tot de bio-informatica encomputationele biologie2. Lab for Bioinformatics andcomputational genomics 10 “genome hackers” mostly engineers (statistics) 42 scientists…

PowerPoint Presentation FBW 08-10-2012 Wim Van Criekinge 2 Inhoud Lessen: Bioinformatica GEEN LES Overview Introduction Short recap on databases Definitions Scoring Matrices…

Lecture 3, 4 and 5: Homology, similarity and identity · Homology: share a common evolutionary ancestry · No degree of homology, yes or no · Share significant homology…

Slide 1 Collagen by Kati Feken Crystal structure of collagen which has three identical helices shown in blue, green, and purple. Each helix consists of 18 residues. View…

Supplementary Figure 1 Supplementary Figures Supplementary Fig. 1 Amino acid sequence alignment of DUF724 domain in plants. Black boxes indicate the identical amino acids,…

Database Searching BLAST Database Searching Sequence Alignment Scoring Matrices Significance of an alignment BLAST, algorithm BLAST, parameters BLAST, output Alignment significance…

Sequence Alignment Sequence Alignment Why: To match a new sequence to others with known functions To search for ESTs and other signs of gene expression To understand population…

PowerPoint Presentation PfDGAT1-1 PfDGAT1-2 AtDGAT1 RcDGAT1 PfDGAT1-1 PfDGAT1-2 AtDGAT1 RcDGAT1 PfDGAT1-1 PfDGAT1-2 AtDGAT1 RcDGAT1 PfDGAT1-1 PfDGAT1-2 AtDGAT1 RcDGAT1 PfDGAT1-1…