1. THAT IS THE JOB SAVING LIVES 2. MINISTRY OF HEALTH OF UKRAINE LUGANSK STATE MEDICAL UNIVERSITY DEPARTMENT OF PEDIATRICS REPORT PRESENTED BY RUBEN GOMBALANDI . SUPERVISED…

Slide 1 Psychopharmacology What you should know to survive the LMCC and Internship Kate Huntington, MD April 2008 Slide 2 Objectives To review: indications for mechanism…

Slide 1 Slide 2 Location of Serotonin Neurons in the Raphe Nuclei Slide 3 Slide 4 IN HUMANS: 90% OF TOTAL BODY SEROTONIN IS FOUND IN GUT. 8% OF TOTAL FOUND IN PLATELETS AND…

Lecture 3 Stimulants of central nervous system 5-Hydroxytryptamine (5-HT) in the CNS 5-Hydroxytryptamine (5-HT) in the CNS The processes of synthesis, storage, release, reuptake…

Psychopharmacology What you should know to survive the LMCC and Internship Kate Huntington, MD April 2008 Objectives To review: indications for mechanism of action side effects…

Triad of systems mediate response to stress Color-enhanced image of the expression of mRNA encoding (a) glucocorticoid receptor (GR) and (b) mineralocorticoid receptor (MR)…

OCD Neurochemical dysfunction (abnormalities in serotonin (5-HT), dopamine (DA), and glutamatergic transmitter systems) Drug Therapy in OCD Strategies targeting these systems…

WHEEL RUNNING ALTERS SEROTONIN (5-HT) TRANSPORTER, 5-HT1A, 5-HT1B, AND ALPHA1B-ADRENERGIC RECEPTOR MRNA IN THE RAT RAPHE NUCLEI Greenwood et al 2005 DEPRESSION Thought to…

Location of Serotonin Neurons in the Raphe Nuclei IN HUMANS: 90% OF TOTAL BODY SEROTONIN IS FOUND IN GUT. 8% OF TOTAL FOUND IN PLATELETS AND MAST CELLS. 1-2% OF TOTAL FOUND…