Slide 1"Towards a Cure”: HIV Reservoirs and Strategies to Control Them IAS WORKSHOP, 16 & 17 JULY 2010 Purging the HIV-1 Reservoir Through the Disruption of the…

2014 “Towards an HIV Cure” symposium Melbourne Synergistic activation of HIV-1 expression by compounds targeting the positive transcription elongation factor b (P-TEFb)…

PowerPoint Presentation Cell- and Tissue-based Measures of Viral Persistence Are Associated with Immune Activation and PD-1-Expressing CD4+ T cells H Hatano1, V Jain1, PW…

Mechanisms of HIV Latency in CD4 T cells Preintegration vs. Postintegration latency t1/2=1-2 weeks t1/2=44 months The HIV Life Cycle What is Latency? The HIV Life Cycle DNA…

Slide 1 The HDAC inhibitor romidepsin is safe and effectively reverses HIV-1 latency in vivo as measured by standard clinical assays Ole Schmeltz Søgaard, MD PhD Department…

Slide 1 "Towards a Cure”: HIV Reservoirs and Strategies to Control Them IAS WORKSHOP, 16 & 17 JULY 2010 Purging the HIV-1 Reservoir Through the Disruption of the…

PowerPoint Presentation Cell- and Tissue-based Measures of Viral Persistence Are Associated with Immune Activation and PD-1-Expressing CD4+ T cells H Hatano1, V Jain1, PW…

MOLECULAR MECHANISMS OF HIV POSTINTEGRATION LATENCY: STRATEGIES FOR ERADICATION How is HIV transcribed? What is latency/reservoir? When is it established? How best to eradicate…