1. Hemoglobin and Insulin 2. Hemoglobin is composed of4 globin molecules.2 alpha globins2 beta globins4 Heme moleculesStructure of Hemoglobin2 3. 3 4. Molecular structure…

Slide 1Hemoglobin Structure & Function Slide 2 Objectives of the Lecture structuralfunctional 1- Understanding the main structural & functional details of hemoglobin…

Slide 1 Red Blood Cells & Anemias Andrew D. Leavitt, MD Departments of Laboratory Medicine & Medicine March 26, 2012 RBC: ~5 x 10 6 /  l; Generate ~ 8,000,000,000/hour…

Slide 1 Hemoglobin Structure & Function HMIM224 Slide 2 Objectives of the Lecture structuralfunctional 1- Understanding the main structural & functional details of…

Slide 1 1 Slide 2 2 Slide 3 Myoglobin Heme 3 Slide 4 4 Slide 5 Hemoglobin (Hb) functions to transport oxygen in the blood of all warm-blooded animals. It is a multimeric…

Slide 1 Oxygen Binding Proteins Slide 2 Oxygen binding proteins (myoglobin and hemoglobin) are hemoproteinsOxygen binding proteins (myoglobin and hemoglobin) are hemoproteins…

Slide 1 Structures of Myoglobin and Hemoglobin Myoglobin (Mb) - monomeric protein that facilitates the diffusion of oxygen in vertebrates Hemoglobin (Hb) - tetrameric protein…

Slide 1EBI is an Outstation of the European Molecular Biology Laboratory. Quaternary Structure Slide 2 What is Quaternary Structure ? Form in which units of tertiary structure…

Slide 1 Hemoglobin Tetramer [Hb(O 2 )] [Hb]P O 2 K 2 = [Hb(O 2 )] [Hb]P O 2 K 3 = [Hb(O 2 )] [Hb]P O 2 K 4 = [Hb(O 2 )] [Hb]P O 2 K 1 = = 4.88 = 15.4 = 6.49 = 1750 Whole…

Slide 1 V. Evolution of Protein Structure and Function Protein structure classification Structural relationships among homologous proteins Changes in proteins during evolution…