Slide 1 Regulatory T cells Slide 2 Control of potential T cell self-reactivity: tolerance Random generation of an immense T-cell repertoire (~ 10 15 different TCRs ): Great…
Doctoral Seminar Title: The Interleukin 12 Family of Cytokines Presented by: M. Sh. Mojadadi Advisor: Dr. M. Ebtekar Outline Overview of the Interleukin 12 family of cytokines…
Christina Ziegler Feb 15th 2010 Mechanisms of tolerance induction Clonal deletion negative selection of thymocytes with high affinity TCR for MHC:self-antigen (central tolerance)…