Slide 1DNA, genes and chromosomes Revise your BI1505/7 notes Textbook - Purves chapters on Chromosomes… and DNA…, Lehninger chapter 24 These 3 lectures will cover the…

Slide 1Lecture 37 Prof Duncan Shaw Slide 2 Textbooks in the library Emery's Elements of Medical Genetics by RF Mueller & ID Young, or PD Turnpenny for latest edition…

1. THE ORGANIZATION OF DNA IN CHROMOSOMES Prokaryotes have a single type of chromosome while most eukaryotes have diploid number of chromosomes in somatic cells and each…

Slide 1 Single Supercoiled DNAs Slide 2 DNA Supercoiling in vivo In most organisms, DNA is negatively supercoiled (  ~ -0.06) Actively regulated by topoisomerases,…

Single Supercoiled DNAs DNA Supercoiling in vivo In most organisms, DNA is negatively supercoiled (s ~ -0.06) Actively regulated by topoisomerases, ubiquitous and essential…