Slide 1A global genetic analysis of nematode spliced-leader trans-splicing Jonathan Pettitt Berndt Mueller Bernadette Connolly Slide 2 Spliced-leader trans-splicing ‘Slintron’…

Slide 1 Working with gene lists: Finding data using GEO & BioMart June 5, 2014 Slide 2 Analyzing a gene list  With hundreds of genes but a limited budget and lab personnel,…

Slide 1 Biochemistry 412 2004 9 April Lecture RNA Interference (RNAi) (see also siRNA, micRNA, stRNA, etc.) Slide 2 The Discovery of the RNA Interference (RNAi) Phenomenon…

Slide 1 Origins of recently gained introns in Caenorhabditis Avril Coghlan and Kenneth H. Wolfe Department of Genetics, Trinity College Dublin, Ireland Slide 2 Rate of intron…

ASSIGNING GENE FUNCTION BY EXPERIMENTAL ANALYSIS Gene inactivation (loss-of-function) - mutate gene (âknock-outâ) and observe change in phenotype Deletion mutagenesis -…

IB404 - Caenorhabditis elegans 1 â Feb 8 1. C. elegans was being studied by a few UK naturalists in the 1960s when South African Sydney Brenner at Cambridge, England decided…

Model Organisms Model Organism Important features of all model organisms Short lifespan Small, easy and inexpensive to maintain Produce large numbers of offspring Development…

Lecture V. Cell Birth and Death Bio 3411 Wednesday September 15, 2010 September 15, 2010 * Lecture V. Cell Birth & Death Lecture V. Cell Birth & Death Readings NEUROSCIENCE:…

ASSIGNING GENE FUNCTION BY EXPERIMENTAL ANALYSIS Gene inactivation (loss-of-function) - mutate gene (âknock-outâ) and observe change in phenotype Deletion mutagenesis -…

Slide 1 A single gene network accurately predicts phenotypic effects of gene perturbation in Caenorhabditis elegans Insuk Lee1,4, Ben Lehner2,3,4, Catriona Crombie2, Wendy…