1.Drug Metabolism Most metabolic products areless pharmacologically active Important exceptions : Where the metabolite is more active(Prodrugs, e.g. Erythromycin-succinate…
Slide 1 POLYPHARMACY Pio L. Oliverio, MD Fellow, Geriatrics SVCMC, Jamaica, NY February 27, 2006 Slide 2 Definition POLYPHARMACY Use of several drugs or medicines together…
Introduction to drug metabolism Phase-II Drug Metabolism Phase-II Drug Metabolism Reactions which conjugate the drug or its phase-I metabolite with a hydrophilic, endogenous…
DRUG ELIMINATION DRUG ELIMINATION LECTURE 5 PHARMACOLOGY Drug Elimination PLASMA Sites of Action Absorption Tissue Depots Unbound Drug Bound Drug Excretion Metabolism 2 Drug…